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XBiotech (XBIT) Competitors

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$2.20 +0.01 (+0.46%)
As of 09/3/2026 04:00 PM Eastern

XBIT vs. ANIK, TRDA, SION, PYXS, and ACIU

Should you buy XBiotech stock or one of its competitors? XBiotech's main competitors and comparable companies include Anika Therapeutics (ANIK), Entrada Therapeutics (TRDA), Sionna Therapeutics (SION), Pyxis Oncology (PYXS), and AC Immune (ACIU). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does XBiotech compare to Anika Therapeutics?

XBiotech (NASDAQ:XBIT) and Anika Therapeutics (NASDAQ:ANIK) are both small-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their profitability, media sentiment, earnings, institutional ownership, dividends, analyst recommendations, valuation and risk.

XBiotech has a net margin of 0.00% compared to Anika Therapeutics' net margin of -3.14%. Anika Therapeutics' return on equity of 0.20% beat XBiotech's return on equity.

Company Net Margins Return on Equity Return on Assets
XBiotechN/A -31.62% -30.29%
Anika Therapeutics -3.14%0.20%0.15%

Anika Therapeutics has higher revenue and earnings than XBiotech. Anika Therapeutics is trading at a lower price-to-earnings ratio than XBiotech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
XBiotechN/AN/A-$45.54M-$1.48N/A
Anika Therapeutics$112.82M2.49-$10.88M-$0.27N/A

55.7% of XBiotech shares are owned by institutional investors. Comparatively, 91.5% of Anika Therapeutics shares are owned by institutional investors. 30.8% of XBiotech shares are owned by company insiders. Comparatively, 12.1% of Anika Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

In the previous week, Anika Therapeutics had 1 more articles in the media than XBiotech. MarketBeat recorded 3 mentions for Anika Therapeutics and 2 mentions for XBiotech. Anika Therapeutics' average media sentiment score of 1.73 beat XBiotech's score of 0.58 indicating that Anika Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
XBiotech
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Anika Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Anika Therapeutics has a consensus price target of $21.00, indicating a potential upside of 0.00%. Given Anika Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Anika Therapeutics is more favorable than XBiotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
XBiotech
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Anika Therapeutics
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.75

XBiotech has a beta of 0.85, suggesting that its share price is 15% less volatile than the broader market. Comparatively, Anika Therapeutics has a beta of 0.2, suggesting that its share price is 80% less volatile than the broader market.

Summary

Anika Therapeutics beats XBiotech on 12 of the 16 factors compared between the two stocks.

How does XBiotech compare to Entrada Therapeutics?

XBiotech (NASDAQ:XBIT) and Entrada Therapeutics (NASDAQ:TRDA) are both small-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their institutional ownership, analyst recommendations, dividends, profitability, media sentiment, earnings, risk and valuation.

XBiotech has a net margin of 0.00% compared to Entrada Therapeutics' net margin of -3,537.73%. XBiotech's return on equity of -31.62% beat Entrada Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
XBiotechN/A -31.62% -30.29%
Entrada Therapeutics -3,537.73%-57.61%-46.54%

55.7% of XBiotech shares are owned by institutional investors. Comparatively, 86.4% of Entrada Therapeutics shares are owned by institutional investors. 30.8% of XBiotech shares are owned by company insiders. Comparatively, 9.5% of Entrada Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

XBiotech has a beta of 0.85, suggesting that its share price is 15% less volatile than the broader market. Comparatively, Entrada Therapeutics has a beta of -0.25, suggesting that its share price is 125% less volatile than the broader market.

In the previous week, Entrada Therapeutics had 14 more articles in the media than XBiotech. MarketBeat recorded 16 mentions for Entrada Therapeutics and 2 mentions for XBiotech. Entrada Therapeutics' average media sentiment score of 0.67 beat XBiotech's score of 0.58 indicating that Entrada Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
XBiotech
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Entrada Therapeutics
9 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Entrada Therapeutics has a consensus target price of $17.75, indicating a potential upside of 147.56%. Given Entrada Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Entrada Therapeutics is more favorable than XBiotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
XBiotech
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Entrada Therapeutics
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.50

XBiotech has higher earnings, but lower revenue than Entrada Therapeutics. Entrada Therapeutics is trading at a lower price-to-earnings ratio than XBiotech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
XBiotechN/AN/A-$45.54M-$1.48N/A
Entrada Therapeutics$25.42M10.98-$143.75M-$3.96N/A

Summary

XBiotech beats Entrada Therapeutics on 8 of the 15 factors compared between the two stocks.

How does XBiotech compare to Sionna Therapeutics?

XBiotech (NASDAQ:XBIT) and Sionna Therapeutics (NASDAQ:SION) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their media sentiment, analyst recommendations, dividends, earnings, profitability, valuation, institutional ownership and risk.

Sionna Therapeutics has a consensus target price of $42.22, indicating a potential upside of 525.51%. Given Sionna Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Sionna Therapeutics is more favorable than XBiotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
XBiotech
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Sionna Therapeutics
1 Sell rating(s)
11 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Sionna Therapeutics is trading at a lower price-to-earnings ratio than XBiotech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
XBiotechN/AN/A-$45.54M-$1.48N/A
Sionna TherapeuticsN/AN/A-$75.27M-$2.18N/A

In the previous week, Sionna Therapeutics had 4 more articles in the media than XBiotech. MarketBeat recorded 6 mentions for Sionna Therapeutics and 2 mentions for XBiotech. XBiotech's average media sentiment score of 0.58 beat Sionna Therapeutics' score of 0.23 indicating that XBiotech is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
XBiotech
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Sionna Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

55.7% of XBiotech shares are held by institutional investors. 30.8% of XBiotech shares are held by company insiders. Comparatively, 5.1% of Sionna Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

XBiotech has a beta of 0.85, indicating that its share price is 15% less volatile than the broader market. Comparatively, Sionna Therapeutics has a beta of 0.89, indicating that its share price is 11% less volatile than the broader market.

XBiotech's return on equity of -31.62% beat Sionna Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
XBiotechN/A -31.62% -30.29%
Sionna Therapeutics N/A -32.94%-31.08%

Summary

XBiotech beats Sionna Therapeutics on 8 of the 13 factors compared between the two stocks.

How does XBiotech compare to Pyxis Oncology?

XBiotech (NASDAQ:XBIT) and Pyxis Oncology (NASDAQ:PYXS) are both small-cap healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their earnings, valuation, analyst recommendations, media sentiment, risk, dividends, profitability and institutional ownership.

55.7% of XBiotech shares are held by institutional investors. Comparatively, 39.1% of Pyxis Oncology shares are held by institutional investors. 30.8% of XBiotech shares are held by insiders. Comparatively, 5.7% of Pyxis Oncology shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

In the previous week, XBiotech had 1 more articles in the media than Pyxis Oncology. MarketBeat recorded 2 mentions for XBiotech and 1 mentions for Pyxis Oncology. XBiotech's average media sentiment score of 0.58 beat Pyxis Oncology's score of 0.00 indicating that XBiotech is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
XBiotech
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pyxis Oncology
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

XBiotech has higher earnings, but lower revenue than Pyxis Oncology. Pyxis Oncology is trading at a lower price-to-earnings ratio than XBiotech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
XBiotechN/AN/A-$45.54M-$1.48N/A
Pyxis Oncology$13.86M21.48-$79.62M-$1.41N/A

Pyxis Oncology has a consensus price target of $7.50, indicating a potential upside of 110.08%. Given Pyxis Oncology's stronger consensus rating and higher probable upside, analysts clearly believe Pyxis Oncology is more favorable than XBiotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
XBiotech
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Pyxis Oncology
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.70

XBiotech has a beta of 0.85, suggesting that its share price is 15% less volatile than the broader market. Comparatively, Pyxis Oncology has a beta of 1.34, suggesting that its share price is 34% more volatile than the broader market.

XBiotech's return on equity of -31.62% beat Pyxis Oncology's return on equity.

Company Net Margins Return on Equity Return on Assets
XBiotechN/A -31.62% -30.29%
Pyxis Oncology N/A -215.23%-112.19%

Summary

XBiotech beats Pyxis Oncology on 8 of the 14 factors compared between the two stocks.

How does XBiotech compare to AC Immune?

XBiotech (NASDAQ:XBIT) and AC Immune (NASDAQ:ACIU) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their valuation, dividends, profitability, institutional ownership, risk, analyst recommendations, earnings and media sentiment.

55.7% of XBiotech shares are owned by institutional investors. Comparatively, 51.4% of AC Immune shares are owned by institutional investors. 30.8% of XBiotech shares are owned by company insiders. Comparatively, 4.6% of AC Immune shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

AC Immune has a consensus target price of $7.50, suggesting a potential upside of 155.97%. Given AC Immune's stronger consensus rating and higher possible upside, analysts clearly believe AC Immune is more favorable than XBiotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
XBiotech
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
AC Immune
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

XBiotech has higher earnings, but lower revenue than AC Immune. AC Immune is trading at a lower price-to-earnings ratio than XBiotech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
XBiotechN/AN/A-$45.54M-$1.48N/A
AC Immune$4.31M69.18-$85.03M-$0.54N/A

XBiotech has a net margin of 0.00% compared to AC Immune's net margin of -245.32%. XBiotech's return on equity of -31.62% beat AC Immune's return on equity.

Company Net Margins Return on Equity Return on Assets
XBiotechN/A -31.62% -30.29%
AC Immune -245.32%-100.17%-28.36%

In the previous week, XBiotech and XBiotech both had 2 articles in the media. AC Immune's average media sentiment score of 1.25 beat XBiotech's score of 0.58 indicating that AC Immune is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
XBiotech
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
AC Immune
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

XBiotech has a beta of 0.85, meaning that its stock price is 15% less volatile than the broader market. Comparatively, AC Immune has a beta of 1.6, meaning that its stock price is 60% more volatile than the broader market.

Summary

AC Immune beats XBiotech on 8 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding XBIT and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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XBIT vs. The Competition

MetricXBiotechBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$66.77M$4.03B$7.26B$12.73B
Dividend YieldN/A3.60%2.53%8.86%
P/E Ratio-1.4912.66273.2825.38
Price / SalesN/A1,309.16613.4892.60
Price / CashN/A106.8777.8252.26
Price / Book0.5216.2912.896.14
Net Income-$45.54M-$22.72M$3.47B$349.01M
7 Day Performance-3.08%0.34%0.61%-0.27%
1 Month Performance-1.79%8.52%5.73%0.68%
1 Year Performance-26.17%52.66%25.37%14.84%

XBiotech Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
XBIT
XBiotech
0.4326 of 5 stars
$2.20
+0.5%
N/A-26.2%$66.77MN/AN/A100
ANIK
Anika Therapeutics
3.1176 of 5 stars
$21.11
+1.1%
$21.00
-0.5%
+133.1%$279.30M$112.82MN/A300
TRDA
Entrada Therapeutics
2.4624 of 5 stars
$7.07
+0.3%
$17.75
+151.1%
+34.8%$274.50M$25.42MN/A110
SION
Sionna Therapeutics
2.7358 of 5 stars
$6.46
+7.1%
$42.22
+553.6%
-72.5%$272.63MN/AN/A35
PYXS
Pyxis Oncology
2.3886 of 5 stars
$3.44
+6.2%
$7.50
+118.0%
+142.9%$270.24M$13.86MN/A60

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This page (NASDAQ:XBIT) was last updated on 9/4/2026 by MarketBeat.com Staff.
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