Free Trial

Prothena (PRTA) Competitors

Prothena logo
$8.79 0.00 (0.00%)
Closing price 06/5/2026 04:00 PM Eastern
Extended Trading
$8.82 +0.03 (+0.32%)
As of 06:37 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PRTA vs. BHC, TRVI, NBTX, MESO, and AAPG

Should you buy Prothena stock or one of its competitors? MarketBeat compares Prothena with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Prothena include Bausch Health Cos (BHC), Trevi Therapeutics (TRVI), Nanobiotix (NBTX), Mesoblast (MESO), and Ascentage Pharma Group International (AAPG). These companies are all part of the "pharmaceutical products" industry.

How does Prothena compare to Bausch Health Cos?

Prothena (NASDAQ:PRTA) and Bausch Health Cos (NYSE:BHC) are both medical companies, but which is the superior investment? We will contrast the two companies based on the strength of their risk, earnings, valuation, media sentiment, analyst recommendations, institutional ownership, profitability and dividends.

Prothena has a beta of -0.25, indicating that its share price is 125% less volatile than the broader market. Comparatively, Bausch Health Cos has a beta of 0.4, indicating that its share price is 60% less volatile than the broader market.

Bausch Health Cos has a net margin of -11.47% compared to Prothena's net margin of -260.92%. Prothena's return on equity of -43.44% beat Bausch Health Cos' return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-260.92% -43.44% -36.87%
Bausch Health Cos -11.47%-2,922.77%5.63%

In the previous week, Prothena had 5 more articles in the media than Bausch Health Cos. MarketBeat recorded 6 mentions for Prothena and 1 mentions for Bausch Health Cos. Prothena's average media sentiment score of 1.56 beat Bausch Health Cos' score of 0.90 indicating that Prothena is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prothena
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Bausch Health Cos
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Prothena presently has a consensus price target of $23.75, suggesting a potential upside of 170.19%. Bausch Health Cos has a consensus price target of $8.00, suggesting a potential upside of 48.84%. Given Prothena's stronger consensus rating and higher possible upside, analysts clearly believe Prothena is more favorable than Bausch Health Cos.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
2 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.63
Bausch Health Cos
1 Sell rating(s)
4 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.80

Bausch Health Cos has higher revenue and earnings than Prothena. Prothena is trading at a lower price-to-earnings ratio than Bausch Health Cos, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$9.68M47.54-$244.09M-$2.82N/A
Bausch Health Cos$10.53B0.19$157M-$3.24N/A

97.1% of Prothena shares are held by institutional investors. Comparatively, 78.7% of Bausch Health Cos shares are held by institutional investors. 10.4% of Prothena shares are held by company insiders. Comparatively, 20.7% of Bausch Health Cos shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Summary

Prothena beats Bausch Health Cos on 10 of the 17 factors compared between the two stocks.

How does Prothena compare to Trevi Therapeutics?

Prothena (NASDAQ:PRTA) and Trevi Therapeutics (NASDAQ:TRVI) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their dividends, earnings, media sentiment, analyst recommendations, institutional ownership, profitability, valuation and risk.

Prothena has a beta of -0.25, suggesting that its stock price is 125% less volatile than the broader market. Comparatively, Trevi Therapeutics has a beta of 1.04, suggesting that its stock price is 4% more volatile than the broader market.

Prothena presently has a consensus price target of $23.75, suggesting a potential upside of 170.19%. Trevi Therapeutics has a consensus price target of $22.90, suggesting a potential upside of 71.79%. Given Prothena's higher probable upside, equities research analysts clearly believe Prothena is more favorable than Trevi Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
2 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.63
Trevi Therapeutics
1 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
2 Strong Buy rating(s)
3.00

Trevi Therapeutics has a net margin of 0.00% compared to Prothena's net margin of -260.92%. Trevi Therapeutics' return on equity of -24.53% beat Prothena's return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-260.92% -43.44% -36.87%
Trevi Therapeutics N/A -24.53%-23.37%

In the previous week, Prothena had 5 more articles in the media than Trevi Therapeutics. MarketBeat recorded 6 mentions for Prothena and 1 mentions for Trevi Therapeutics. Prothena's average media sentiment score of 1.56 beat Trevi Therapeutics' score of 0.46 indicating that Prothena is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prothena
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Trevi Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

97.1% of Prothena shares are held by institutional investors. Comparatively, 95.8% of Trevi Therapeutics shares are held by institutional investors. 10.4% of Prothena shares are held by company insiders. Comparatively, 18.3% of Trevi Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Trevi Therapeutics has lower revenue, but higher earnings than Prothena. Trevi Therapeutics is trading at a lower price-to-earnings ratio than Prothena, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$9.68M47.54-$244.09M-$2.82N/A
Trevi TherapeuticsN/AN/A-$42.76M-$0.32N/A

Summary

Trevi Therapeutics beats Prothena on 10 of the 16 factors compared between the two stocks.

How does Prothena compare to Nanobiotix?

Prothena (NASDAQ:PRTA) and Nanobiotix (NASDAQ:NBTX) are both small-cap medical companies, but which is the better stock? We will compare the two businesses based on the strength of their valuation, earnings, analyst recommendations, institutional ownership, profitability, dividends, risk and media sentiment.

Prothena currently has a consensus target price of $23.75, suggesting a potential upside of 170.19%. Nanobiotix has a consensus target price of $37.33, suggesting a potential upside of 5.28%. Given Prothena's stronger consensus rating and higher possible upside, equities research analysts plainly believe Prothena is more favorable than Nanobiotix.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
2 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.63
Nanobiotix
1 Sell rating(s)
1 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.50

In the previous week, Prothena had 3 more articles in the media than Nanobiotix. MarketBeat recorded 6 mentions for Prothena and 3 mentions for Nanobiotix. Prothena's average media sentiment score of 1.56 beat Nanobiotix's score of 0.00 indicating that Prothena is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prothena
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Nanobiotix
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Nanobiotix has a net margin of 0.00% compared to Prothena's net margin of -260.92%. Nanobiotix's return on equity of 0.00% beat Prothena's return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-260.92% -43.44% -36.87%
Nanobiotix N/A N/A N/A

Prothena has a beta of -0.25, suggesting that its share price is 125% less volatile than the broader market. Comparatively, Nanobiotix has a beta of 0.73, suggesting that its share price is 27% less volatile than the broader market.

Nanobiotix has higher revenue and earnings than Prothena.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$9.68M47.54-$244.09M-$2.82N/A
Nanobiotix$36.87M46.66-$27.11MN/AN/A

97.1% of Prothena shares are held by institutional investors. Comparatively, 38.8% of Nanobiotix shares are held by institutional investors. 10.4% of Prothena shares are held by company insiders. Comparatively, 3.5% of Nanobiotix shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Summary

Prothena beats Nanobiotix on 8 of the 14 factors compared between the two stocks.

How does Prothena compare to Mesoblast?

Mesoblast (NASDAQ:MESO) and Prothena (NASDAQ:PRTA) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, media sentiment, dividends, profitability, valuation, earnings, risk and institutional ownership.

In the previous week, Prothena had 4 more articles in the media than Mesoblast. MarketBeat recorded 6 mentions for Prothena and 2 mentions for Mesoblast. Prothena's average media sentiment score of 1.56 beat Mesoblast's score of 0.18 indicating that Prothena is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mesoblast
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
Prothena
2 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Mesoblast has a beta of 2.05, indicating that its share price is 105% more volatile than the broader market. Comparatively, Prothena has a beta of -0.25, indicating that its share price is 125% less volatile than the broader market.

Mesoblast has a net margin of 0.00% compared to Prothena's net margin of -260.92%. Mesoblast's return on equity of 0.00% beat Prothena's return on equity.

Company Net Margins Return on Equity Return on Assets
MesoblastN/A N/A N/A
Prothena -260.92%-43.44%-36.87%

Mesoblast has higher revenue and earnings than Prothena. Mesoblast is trading at a lower price-to-earnings ratio than Prothena, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mesoblast$65.38M27.62-$102.14M-$0.54N/A
Prothena$9.68M47.54-$244.09M-$2.82N/A

1.4% of Mesoblast shares are held by institutional investors. Comparatively, 97.1% of Prothena shares are held by institutional investors. 18.8% of Mesoblast shares are held by company insiders. Comparatively, 10.4% of Prothena shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth.

Prothena has a consensus price target of $23.75, indicating a potential upside of 170.19%. Given Prothena's stronger consensus rating and higher possible upside, analysts clearly believe Prothena is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mesoblast
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33
Prothena
1 Sell rating(s)
2 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.63

Summary

Mesoblast and Prothena tied by winning 8 of the 16 factors compared between the two stocks.

How does Prothena compare to Ascentage Pharma Group International?

Prothena (NASDAQ:PRTA) and Ascentage Pharma Group International (NASDAQ:AAPG) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their risk, media sentiment, valuation, institutional ownership, earnings, dividends, analyst recommendations and profitability.

Prothena has a beta of -0.25, indicating that its share price is 125% less volatile than the broader market. Comparatively, Ascentage Pharma Group International has a beta of -0.04, indicating that its share price is 104% less volatile than the broader market.

97.1% of Prothena shares are held by institutional investors. 10.4% of Prothena shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

In the previous week, Prothena had 6 more articles in the media than Ascentage Pharma Group International. MarketBeat recorded 6 mentions for Prothena and 0 mentions for Ascentage Pharma Group International. Prothena's average media sentiment score of 1.56 beat Ascentage Pharma Group International's score of 0.00 indicating that Prothena is being referred to more favorably in the media.

Company Overall Sentiment
Prothena Very Positive
Ascentage Pharma Group International Neutral

Ascentage Pharma Group International has a net margin of 0.00% compared to Prothena's net margin of -260.92%. Ascentage Pharma Group International's return on equity of 0.00% beat Prothena's return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-260.92% -43.44% -36.87%
Ascentage Pharma Group International N/A N/A N/A

Prothena currently has a consensus price target of $23.75, suggesting a potential upside of 170.19%. Ascentage Pharma Group International has a consensus price target of $46.67, suggesting a potential upside of 166.99%. Given Prothena's higher possible upside, research analysts plainly believe Prothena is more favorable than Ascentage Pharma Group International.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
2 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.63
Ascentage Pharma Group International
0 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
2 Strong Buy rating(s)
3.25

Ascentage Pharma Group International has higher revenue and earnings than Prothena.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$9.68M47.54-$244.09M-$2.82N/A
Ascentage Pharma Group International$82.10M19.87-$177.71MN/AN/A

Summary

Ascentage Pharma Group International beats Prothena on 9 of the 15 factors compared between the two stocks.

Get Prothena News Delivered to You Automatically

Sign up to receive the latest news and ratings for PRTA and its competitors with MarketBeat's FREE daily newsletter.

Subscribe Now
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.

New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PRTA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Skip Chart

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Skip Chart

PRTA vs. The Competition

MetricProthenaMED IndustryMedical SectorNASDAQ Exchange
Market Cap$460.16M$3.33B$6.46B$11.98B
Dividend YieldN/A2.30%2.67%5.55%
P/E Ratio-3.1219.0223.8523.62
Price / Sales47.54297.09512.48110.29
Price / CashN/A51.4526.9937.25
Price / Book1.697.9710.276.66
Net Income-$244.09M$23.89M$3.57B$337.72M
7 Day Performance-8.34%-5.14%-0.94%-3.74%
1 Month Performance-18.08%2.54%3.53%0.95%
1 Year Performance62.48%36.80%23.78%25.35%

Prothena Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PRTA
Prothena
3.0234 of 5 stars
$8.79
flat
$23.75
+170.2%
+62.5%$460.16M$9.68MN/A130
BHC
Bausch Health Cos
3.4602 of 5 stars
$5.47
-0.1%
$8.00
+46.4%
+13.2%$2.04B$10.27BN/A20,300
TRVI
Trevi Therapeutics
3.2798 of 5 stars
$14.13
flat
$22.90
+62.1%
+88.8%$2.01BN/AN/A20
NBTX
Nanobiotix
2.2428 of 5 stars
$41.01
flat
$26.67
-35.0%
+652.9%$1.99B$36.87MN/A100
MESO
Mesoblast
1.0861 of 5 stars
$15.20
flat
N/A+18.3%$1.97B$17.20MN/A80

Related Companies and Tools


This page (NASDAQ:PRTA) was last updated on 6/8/2026 by MarketBeat.com Staff.
From Our Partners