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Prothena (PRTA) Competitors

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$8.33 -0.13 (-1.54%)
As of 11:27 AM Eastern
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PRTA vs. VIR, KLRA, RXRX, DMRA, and FBRX

Should you buy Prothena stock or one of its competitors? Prothena's main competitors and comparable companies include Vir Biotechnology (VIR), Kailera Therapeutics (KLRA), Recursion Pharmaceuticals (RXRX), Damora Therapeutics, Inc. Common Stock (DMRA), and Forte Biosciences (FBRX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Prothena compare to Vir Biotechnology?

Prothena (NASDAQ:PRTA) and Vir Biotechnology (NASDAQ:VIR) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their valuation, dividends, profitability, institutional ownership, risk, analyst recommendations, earnings and media sentiment.

97.1% of Prothena shares are owned by institutional investors. Comparatively, 65.3% of Vir Biotechnology shares are owned by institutional investors. 10.4% of Prothena shares are owned by company insiders. Comparatively, 2.9% of Vir Biotechnology shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Prothena presently has a consensus target price of $24.57, suggesting a potential upside of 194.98%. Vir Biotechnology has a consensus target price of $21.57, suggesting a potential upside of 102.57%. Given Prothena's higher possible upside, research analysts clearly believe Prothena is more favorable than Vir Biotechnology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.75
Vir Biotechnology
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

Prothena has a net margin of -80.68% compared to Vir Biotechnology's net margin of -638.88%. Prothena's return on equity of -16.45% beat Vir Biotechnology's return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-80.68% -16.45% -14.51%
Vir Biotechnology -638.88%-29.99%-23.62%

Prothena has a beta of -0.33, meaning that its stock price is 133% less volatile than the broader market. Comparatively, Vir Biotechnology has a beta of 1.63, meaning that its stock price is 63% more volatile than the broader market.

In the previous week, Vir Biotechnology had 2 more articles in the media than Prothena. MarketBeat recorded 3 mentions for Vir Biotechnology and 1 mentions for Prothena. Prothena's average media sentiment score of 1.87 beat Vir Biotechnology's score of 1.27 indicating that Prothena is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prothena
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Vir Biotechnology
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Prothena has higher earnings, but lower revenue than Vir Biotechnology. Prothena is trading at a lower price-to-earnings ratio than Vir Biotechnology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$9.68M45.05-$244.09M-$0.84N/A
Vir Biotechnology$302.59M5.96-$437.99M-$1.86N/A

Summary

Prothena beats Vir Biotechnology on 10 of the 16 factors compared between the two stocks.

How does Prothena compare to Kailera Therapeutics?

Prothena (NASDAQ:PRTA) and Kailera Therapeutics (NASDAQ:KLRA) are both small-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their valuation, risk, earnings, dividends, analyst recommendations, institutional ownership, profitability and media sentiment.

Kailera Therapeutics has lower revenue, but higher earnings than Prothena. Prothena is trading at a lower price-to-earnings ratio than Kailera Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$9.68M45.05-$244.09M-$0.84N/A
Kailera TherapeuticsN/AN/A-$148.96M-$3.65 thousandN/A

97.1% of Prothena shares are held by institutional investors. 10.4% of Prothena shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Kailera Therapeutics has a net margin of 0.00% compared to Prothena's net margin of -80.68%. Kailera Therapeutics' return on equity of 0.00% beat Prothena's return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-80.68% -16.45% -14.51%
Kailera Therapeutics N/A N/A N/A

In the previous week, Kailera Therapeutics had 8 more articles in the media than Prothena. MarketBeat recorded 9 mentions for Kailera Therapeutics and 1 mentions for Prothena. Prothena's average media sentiment score of 1.87 beat Kailera Therapeutics' score of 0.13 indicating that Prothena is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prothena
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Kailera Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral

Prothena currently has a consensus target price of $24.57, suggesting a potential upside of 194.98%. Kailera Therapeutics has a consensus target price of $42.75, suggesting a potential upside of 243.65%. Given Kailera Therapeutics' higher probable upside, analysts clearly believe Kailera Therapeutics is more favorable than Prothena.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.75
Kailera Therapeutics
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.75

Summary

Kailera Therapeutics beats Prothena on 7 of the 12 factors compared between the two stocks.

How does Prothena compare to Recursion Pharmaceuticals?

Prothena (NASDAQ:PRTA) and Recursion Pharmaceuticals (NASDAQ:RXRX) are both small-cap healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their media sentiment, risk, earnings, institutional ownership, dividends, analyst recommendations, valuation and profitability.

97.1% of Prothena shares are held by institutional investors. Comparatively, 89.1% of Recursion Pharmaceuticals shares are held by institutional investors. 10.4% of Prothena shares are held by insiders. Comparatively, 6.7% of Recursion Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Prothena currently has a consensus price target of $24.57, suggesting a potential upside of 194.98%. Recursion Pharmaceuticals has a consensus price target of $8.06, suggesting a potential upside of 120.52%. Given Prothena's stronger consensus rating and higher probable upside, equities analysts plainly believe Prothena is more favorable than Recursion Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.75
Recursion Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.20

Prothena has higher earnings, but lower revenue than Recursion Pharmaceuticals. Prothena is trading at a lower price-to-earnings ratio than Recursion Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$9.68M45.05-$244.09M-$0.84N/A
Recursion Pharmaceuticals$53.94M36.28-$644.76M-$1.04N/A

In the previous week, Recursion Pharmaceuticals had 8 more articles in the media than Prothena. MarketBeat recorded 9 mentions for Recursion Pharmaceuticals and 1 mentions for Prothena. Prothena's average media sentiment score of 1.87 beat Recursion Pharmaceuticals' score of 0.44 indicating that Prothena is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prothena
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Recursion Pharmaceuticals
3 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Prothena has a net margin of -80.68% compared to Recursion Pharmaceuticals' net margin of -945.94%. Prothena's return on equity of -16.45% beat Recursion Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-80.68% -16.45% -14.51%
Recursion Pharmaceuticals -945.94%-50.41%-38.25%

Prothena has a beta of -0.33, indicating that its stock price is 133% less volatile than the broader market. Comparatively, Recursion Pharmaceuticals has a beta of 1.07, indicating that its stock price is 7% more volatile than the broader market.

Summary

Prothena beats Recursion Pharmaceuticals on 13 of the 17 factors compared between the two stocks.

How does Prothena compare to Damora Therapeutics, Inc. Common Stock?

Prothena (NASDAQ:PRTA) and Damora Therapeutics, Inc. Common Stock (NASDAQ:DMRA) are both small-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their media sentiment, institutional ownership, risk, analyst recommendations, dividends, valuation, earnings and profitability.

97.1% of Prothena shares are held by institutional investors. Comparatively, 14.2% of Damora Therapeutics, Inc. Common Stock shares are held by institutional investors. 10.4% of Prothena shares are held by insiders. Comparatively, 0.4% of Damora Therapeutics, Inc. Common Stock shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

In the previous week, Damora Therapeutics, Inc. Common Stock had 2 more articles in the media than Prothena. MarketBeat recorded 3 mentions for Damora Therapeutics, Inc. Common Stock and 1 mentions for Prothena. Prothena's average media sentiment score of 1.87 beat Damora Therapeutics, Inc. Common Stock's score of 0.51 indicating that Prothena is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prothena
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Damora Therapeutics, Inc. Common Stock
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Damora Therapeutics, Inc. Common Stock has lower revenue, but higher earnings than Prothena. Prothena is trading at a lower price-to-earnings ratio than Damora Therapeutics, Inc. Common Stock, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$9.68M45.05-$244.09M-$0.84N/A
Damora Therapeutics, Inc. Common StockN/AN/A-$209.84M-$3.37N/A

Prothena presently has a consensus target price of $24.57, suggesting a potential upside of 194.98%. Damora Therapeutics, Inc. Common Stock has a consensus target price of $44.00, suggesting a potential upside of 89.74%. Given Prothena's higher possible upside, analysts clearly believe Prothena is more favorable than Damora Therapeutics, Inc. Common Stock.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.75
Damora Therapeutics, Inc. Common Stock
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
3.00

Damora Therapeutics, Inc. Common Stock has a net margin of 0.00% compared to Prothena's net margin of -80.68%. Prothena's return on equity of -16.45% beat Damora Therapeutics, Inc. Common Stock's return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-80.68% -16.45% -14.51%
Damora Therapeutics, Inc. Common Stock N/A -176.39%-77.86%

Prothena has a beta of -0.33, suggesting that its stock price is 133% less volatile than the broader market. Comparatively, Damora Therapeutics, Inc. Common Stock has a beta of 1.46, suggesting that its stock price is 46% more volatile than the broader market.

Summary

Prothena and Damora Therapeutics, Inc. Common Stock tied by winning 8 of the 16 factors compared between the two stocks.

How does Prothena compare to Forte Biosciences?

Prothena (NASDAQ:PRTA) and Forte Biosciences (NASDAQ:FBRX) are both small-cap healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their analyst recommendations, risk, profitability, valuation, dividends, institutional ownership, earnings and media sentiment.

Forte Biosciences has a net margin of 0.00% compared to Prothena's net margin of -80.68%. Prothena's return on equity of -16.45% beat Forte Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-80.68% -16.45% -14.51%
Forte Biosciences N/A -94.82%-77.68%

Prothena presently has a consensus price target of $24.57, indicating a potential upside of 194.98%. Forte Biosciences has a consensus price target of $71.67, indicating a potential downside of 6.91%. Given Prothena's stronger consensus rating and higher possible upside, equities research analysts plainly believe Prothena is more favorable than Forte Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.75
Forte Biosciences
1 Sell rating(s)
4 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

97.1% of Prothena shares are owned by institutional investors. Comparatively, 77.6% of Forte Biosciences shares are owned by institutional investors. 10.4% of Prothena shares are owned by company insiders. Comparatively, 4.4% of Forte Biosciences shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Forte Biosciences has lower revenue, but higher earnings than Prothena. Forte Biosciences is trading at a lower price-to-earnings ratio than Prothena, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$9.68M45.05-$244.09M-$0.84N/A
Forte BiosciencesN/AN/A-$69.38M-$4.65N/A

In the previous week, Prothena had 1 more articles in the media than Forte Biosciences. MarketBeat recorded 1 mentions for Prothena and 0 mentions for Forte Biosciences. Prothena's average media sentiment score of 1.87 beat Forte Biosciences' score of 0.00 indicating that Prothena is being referred to more favorably in the media.

Company Overall Sentiment
Prothena Very Positive
Forte Biosciences Neutral

Prothena has a beta of -0.33, suggesting that its share price is 133% less volatile than the broader market. Comparatively, Forte Biosciences has a beta of 2.62, suggesting that its share price is 162% more volatile than the broader market.

Summary

Prothena beats Forte Biosciences on 13 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PRTA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PRTA vs. The Competition

MetricProthenaBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$436.08M$3.88B$7.20B$13.99B
Dividend YieldN/A3.65%2.57%12.64%
P/E Ratio-9.9214.02274.3625.47
Price / Sales45.051,544.64684.04100.00
Price / CashN/A109.1477.0151.20
Price / Book1.6015.4410.476.28
Net Income-$244.09M-$22.78M$3.48B$358.12M
7 Day Performance-6.72%-1.10%0.94%1.24%
1 Month Performance-4.36%-1.58%-0.03%-2.10%
1 Year Performance1.83%35.91%18.28%5.07%

Prothena Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PRTA
Prothena
3.4889 of 5 stars
$8.33
-1.5%
$24.57
+195.0%
+5.0%$436.08M$9.68MN/A67
VIR
Vir Biotechnology
1.8837 of 5 stars
$10.27
-4.6%
$21.57
+110.0%
+127.5%$1.74B$302.59MN/A367
KLRA
Kailera Therapeutics
3.156 of 5 stars
$13.39
-2.6%
$42.75
+219.3%
N/A$1.74BN/AN/A145
RXRX
Recursion Pharmaceuticals
1.5821 of 5 stars
$3.24
-5.1%
$8.06
+149.1%
-24.8%$1.73B$53.94MN/A600
DMRA
Damora Therapeutics, Inc. Common Stock
2.7196 of 5 stars
$26.65
-6.1%
$44.00
+65.1%
+699.3%$1.65BN/AN/A40

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This page (NASDAQ:PRTA) was last updated on 9/18/2026 by MarketBeat.com Staff.
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