NASDAQ:PVLA Palvella Therapeutics (PVLA) Stock Price, News & Analysis $154.84 +6.63 (+4.47%) Closing price 06/29/2026 04:00 PM EasternExtended Trading$154.51 -0.33 (-0.21%) As of 06/29/2026 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Palvella Therapeutics Stock (NASDAQ:PVLA) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Palvella Therapeutics alerts:Sign Up Key Stats Today's Range$143.53▼$155.0050-Day Range$102.19▼$154.8452-Week Range$21.55▼$155.00Volume324,487 shsAverage Volume325,553 shsMarket Capitalization$2.22 billionP/E RatioN/ADividend YieldN/APrice Target$199.53Consensus RatingModerate Buy Company Overview Palvella Therapeutics, Inc. (NASDAQ: PVLA) is a clinical‐stage biopharmaceutical company devoted to the discovery and development of innovative therapies for immunological and inflammatory diseases. The company employs a proprietary small‐molecule and biologics platform to identify and modulate key molecular pathways that drive neutrophil‐ and complement‐mediated inflammation, aiming to deliver targeted treatment options for patients with significant unmet medical needs. Palvella’s pipeline comprises several preclinical assets designed to address both prevalent chronic inflammatory conditions and rare autoinflammatory syndromes. Utilizing its integrated chemistry and biology capabilities, the company seeks to optimize drug candidates for favorable pharmacokinetics, safety, and efficacy profiles. Palvella has also established strategic partnerships with academic institutions and industry collaborators to accelerate its research and development efforts. Headquartered in the United States, Palvella Therapeutics operates a dedicated research and development center where its multidisciplinary team of experts in immunology, medicinal chemistry, and clinical sciences drives program advancement. Since its inception, the company has demonstrated a commitment to expanding its pipeline through both internal discovery and external collaborations, with the ultimate goal of bringing new treatment options to patients suffering from debilitating inflammatory diseases.AI Generated. May Contain Errors. Read More Palvella Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks60th Percentile Overall ScorePVLA MarketRank™: Palvella Therapeutics scored higher than 60% of companies evaluated by MarketBeat, and ranked 367th out of 851 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.9 / 5Analyst RatingModerate Buy Consensus RatingPalvella Therapeutics has received a consensus rating of Moderate Buy. The company's average rating score is 2.94, and is based on 1 strong buy rating, 14 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialPalvella Therapeutics has a consensus price target of $199.53, representing about 28.9% upside from its current price of $154.84.Amount of Analyst CoveragePalvella Therapeutics has only been the subject of 2 research reports in the past 90 days.Read more about Palvella Therapeutics' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Palvella Therapeutics are expected to decrease in the coming year, from ($5.26) to ($6.60) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Palvella Therapeutics is -37.13, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Palvella Therapeutics is -37.13, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioPalvella Therapeutics has a P/B Ratio of 65.61. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Palvella Therapeutics' valuation and earnings. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted17.49% of the float of Palvella Therapeutics has been sold short.Short Interest Ratio / Days to CoverPalvella Therapeutics has a short interest ratio ("days to cover") of 6.53.Change versus previous monthShort interest in Palvella Therapeutics has recently decreased by 1.95%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldPalvella Therapeutics does not currently pay a dividend.Dividend GrowthPalvella Therapeutics does not have a long track record of dividend growth. News and Social Media3.5 / 5News Sentiment0.61 News SentimentPalvella Therapeutics has a news sentiment score of 0.61. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.86 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 7 news articles for Palvella Therapeutics this week, compared to 5 articles on an average week.Search Interest1 people have searched for PVLA on MarketBeat in the last 30 days. MarketBeat Follows5 people have added Palvella Therapeutics to their MarketBeat watchlist in the last 30 days. Company Ownership1.8 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Palvella Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $476,360.00 in company stock.Percentage Held by Insiders17.20% of the stock of Palvella Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions40.11% of the stock of Palvella Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Palvella Therapeutics' insider trading history. Receive PVLA Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Palvella Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. PVLA Stock News HeadlinesPalvella Therapeutics Submits First Rolling NDA Module for QTORIN Rapamycin in Microcystic Lymphatic MalformationsJune 29 at 7:50 AM | quiverquant.comQPalvella Therapeutics Submits First Module of Rolling New Drug Application to FDA for QTORIN™ Rapamycin for the Treatment of Microcystic Lymphatic MalformationsJune 29 at 7:30 AM | globenewswire.comThey proved it worked in '76. Then buried it.In 1976, Chevron, Unocal, and Texaco each confirmed the same energy technology worked - no fuel costs, no carbon, no supply chain. All three killed their projects because it threatened their core business. Now one company has spent sixty years developing what Big Oil refused to touch. Google just signed a 15-year contract, Bill Gates wrote a $100 million check, and on July 4th the government hands it a competitive edge no other energy source receives. | Behind the Markets (Ad)What to Know About This $476,000 Palvella Therapeutics Insider Sale After a 620% Stock RallyJune 27 at 12:11 PM | fool.comAnalysts Offer Insights on Healthcare Companies: Palvella Therapeutics (PVLA), Tyra Bioscience (TYRA) and Revolution Medicines (RVMD)June 27 at 7:23 AM | theglobeandmail.comBrokerages Set Palvella Therapeutics, Inc. (NASDAQ:PVLA) Target Price at $199.53June 23, 2026 | americanbankingnews.comKathleen Goin Sells 4,302 Shares of Palvella Therapeutics (NASDAQ:PVLA) StockJune 23, 2026 | insidertrades.comFDA Grants Rolling Review of Palvella’s QTORIN™ Rapamycin NDA for Microcystic Lymphatic MalformationsJune 22, 2026 | markets.businessinsider.comSee More Headlines PVLA Stock Analysis - Frequently Asked Questions How have PVLA shares performed this year? Palvella Therapeutics' stock was trading at $104.67 on January 1st, 2026. Since then, PVLA shares have increased by 47.9% and is now trading at $154.84. How were Palvella Therapeutics' earnings last quarter? Palvella Therapeutics, Inc. (NASDAQ:PVLA) announced its earnings results on Thursday, May, 7th. The company reported ($1.20) EPS for the quarter, missing the consensus estimate of ($0.90) by $0.30. Read the conference call transcript. Who are Palvella Therapeutics' major shareholders? Top institutional investors of Palvella Therapeutics include First Light Asset Management LLC (6.84%), Jennison Associates LLC (4.47%), Siren L.L.C. (1.80%) and Emerald Advisers LLC (1.13%). Insiders that own company stock include George M Jenkins, Elaine J Heron and Kathleen Goin. View institutional ownership trends. How do I buy shares of Palvella Therapeutics? Shares of PVLA stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. Company Calendar Last Earnings5/07/2026Today6/29/2026Next Earnings (Estimated)8/13/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (18m+) 1-Year History Jun 25 Sep 25 Dec 25 Mar 26 Jun 26 PVLA's financial health is in the Green zone, according to TradeSmith. PVLA has been in this zone for over 18 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:PVLA Previous SymbolNASDAQ:PVLA CIK1583648 Webwww.pieris.com Phone857-246-8998Fax49-8161-141-1444EmployeesN/AYear Founded2015Price Target and Rating Average Price Target for Palvella Therapeutics$199.53 High Price Target$270.00 Low Price Target$90.00 Potential Upside/Downside+28.9%Consensus RatingModerate Buy Rating Score (0-4)2.94 Research Coverage16 Analysts Profitability EPS (Trailing Twelve Months)($4.17) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$41.72 million Net MarginsN/A Pretax MarginN/A Return on Equity-56.87% Return on Assets-42.50% Debt Debt-to-Equity RatioN/A Current Ratio28.88 Quick Ratio28.88 Sales & Book Value Annual Sales$42.81 million Price / Sales51.87 Cash FlowN/A Price / Cash FlowN/A Book Value$2.36 per share Price / Book65.61Miscellaneous Outstanding Shares14,340,000Free Float11,876,000Market Cap$2.22 billion OptionableN/A Beta-0.14 Social Links 7 Energy Stocks to Buy and Hold ForeverWith the proliferation of data centers and electric vehicles, the electric grid will only get more strained. 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