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Palvella Therapeutics (PVLA) Competitors

Palvella Therapeutics logo
$157.24 0.00 (0.00%)
Closing price 07/17/2026 04:00 PM Eastern
Extended Trading
$156.96 -0.28 (-0.18%)
As of 07/17/2026 07:52 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PVLA vs. TGTX, APGE, SYRE, PCVX, and IMVT

Should you buy Palvella Therapeutics stock or one of its competitors? MarketBeat compares Palvella Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Palvella Therapeutics include TG Therapeutics (TGTX), Apogee Therapeutics (APGE), Spyre Therapeutics (SYRE), Vaxcyte (PCVX), and Immunovant (IMVT). These companies are all part of the "pharmaceutical products" industry.

How does Palvella Therapeutics compare to TG Therapeutics?

Palvella Therapeutics (NASDAQ:PVLA) and TG Therapeutics (NASDAQ:TGTX) are both mid-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their analyst recommendations, profitability, valuation, risk, earnings, media sentiment, institutional ownership and dividends.

TG Therapeutics has higher revenue and earnings than Palvella Therapeutics. Palvella Therapeutics is trading at a lower price-to-earnings ratio than TG Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Palvella Therapeutics$42.81M52.67-$41.72M-$4.17N/A
TG Therapeutics$616.29M13.63$447.18M$2.8619.19

Palvella Therapeutics has a beta of -0.2, indicating that its stock price is 120% less volatile than the broader market. Comparatively, TG Therapeutics has a beta of 1.6, indicating that its stock price is 60% more volatile than the broader market.

40.1% of Palvella Therapeutics shares are held by institutional investors. Comparatively, 58.6% of TG Therapeutics shares are held by institutional investors. 17.2% of Palvella Therapeutics shares are held by company insiders. Comparatively, 8.9% of TG Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

TG Therapeutics has a net margin of 65.95% compared to Palvella Therapeutics' net margin of 0.00%. TG Therapeutics' return on equity of 88.73% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Palvella TherapeuticsN/A -56.87% -42.50%
TG Therapeutics 65.95%88.73%43.44%

In the previous week, TG Therapeutics had 9 more articles in the media than Palvella Therapeutics. MarketBeat recorded 18 mentions for TG Therapeutics and 9 mentions for Palvella Therapeutics. Palvella Therapeutics' average media sentiment score of 0.92 beat TG Therapeutics' score of 0.37 indicating that Palvella Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Palvella Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
TG Therapeutics
4 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Palvella Therapeutics currently has a consensus price target of $199.53, suggesting a potential upside of 26.90%. TG Therapeutics has a consensus price target of $53.33, suggesting a potential downside of 2.80%. Given Palvella Therapeutics' stronger consensus rating and higher probable upside, research analysts clearly believe Palvella Therapeutics is more favorable than TG Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
TG Therapeutics
1 Sell rating(s)
3 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.56

Summary

TG Therapeutics beats Palvella Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Palvella Therapeutics compare to Apogee Therapeutics?

Palvella Therapeutics (NASDAQ:PVLA) and Apogee Therapeutics (NASDAQ:APGE) are both mid-cap medical companies, but which is the better investment? We will compare the two businesses based on the strength of their institutional ownership, media sentiment, dividends, valuation, risk, profitability, earnings and analyst recommendations.

In the previous week, Palvella Therapeutics had 4 more articles in the media than Apogee Therapeutics. MarketBeat recorded 9 mentions for Palvella Therapeutics and 5 mentions for Apogee Therapeutics. Apogee Therapeutics' average media sentiment score of 1.06 beat Palvella Therapeutics' score of 0.92 indicating that Apogee Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Palvella Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Apogee Therapeutics
3 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

40.1% of Palvella Therapeutics shares are owned by institutional investors. Comparatively, 79.0% of Apogee Therapeutics shares are owned by institutional investors. 17.2% of Palvella Therapeutics shares are owned by company insiders. Comparatively, 24.3% of Apogee Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Palvella Therapeutics has higher revenue and earnings than Apogee Therapeutics. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Apogee Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Palvella Therapeutics$42.81M52.67-$41.72M-$4.17N/A
Apogee TherapeuticsN/AN/A-$255.84M-$4.33N/A

Palvella Therapeutics has a beta of -0.2, meaning that its stock price is 120% less volatile than the broader market. Comparatively, Apogee Therapeutics has a beta of 0.32, meaning that its stock price is 68% less volatile than the broader market.

Apogee Therapeutics' return on equity of -32.64% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Palvella TherapeuticsN/A -56.87% -42.50%
Apogee Therapeutics N/A -32.64%-31.25%

Palvella Therapeutics presently has a consensus price target of $199.53, suggesting a potential upside of 26.90%. Apogee Therapeutics has a consensus price target of $121.25, suggesting a potential downside of 9.51%. Given Palvella Therapeutics' stronger consensus rating and higher probable upside, equities research analysts plainly believe Palvella Therapeutics is more favorable than Apogee Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
Apogee Therapeutics
1 Sell rating(s)
15 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.24

Summary

Palvella Therapeutics and Apogee Therapeutics tied by winning 7 of the 14 factors compared between the two stocks.

How does Palvella Therapeutics compare to Spyre Therapeutics?

Palvella Therapeutics (NASDAQ:PVLA) and Spyre Therapeutics (NASDAQ:SYRE) are both mid-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their earnings, analyst recommendations, institutional ownership, profitability, valuation, media sentiment, dividends and risk.

40.1% of Palvella Therapeutics shares are owned by institutional investors. Comparatively, 80.4% of Spyre Therapeutics shares are owned by institutional investors. 17.2% of Palvella Therapeutics shares are owned by insiders. Comparatively, 15.7% of Spyre Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Palvella Therapeutics has a beta of -0.2, meaning that its share price is 120% less volatile than the broader market. Comparatively, Spyre Therapeutics has a beta of 3.02, meaning that its share price is 202% more volatile than the broader market.

In the previous week, Palvella Therapeutics had 3 more articles in the media than Spyre Therapeutics. MarketBeat recorded 9 mentions for Palvella Therapeutics and 6 mentions for Spyre Therapeutics. Palvella Therapeutics' average media sentiment score of 0.92 beat Spyre Therapeutics' score of 0.62 indicating that Palvella Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Palvella Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Spyre Therapeutics
1 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Spyre Therapeutics' return on equity of -42.88% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Palvella TherapeuticsN/A -56.87% -42.50%
Spyre Therapeutics N/A -42.88%-27.76%

Palvella Therapeutics presently has a consensus price target of $199.53, suggesting a potential upside of 26.90%. Spyre Therapeutics has a consensus price target of $101.42, suggesting a potential upside of 1.18%. Given Palvella Therapeutics' stronger consensus rating and higher probable upside, equities analysts plainly believe Palvella Therapeutics is more favorable than Spyre Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
Spyre Therapeutics
1 Sell rating(s)
0 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.92

Palvella Therapeutics has higher revenue and earnings than Spyre Therapeutics. Spyre Therapeutics is trading at a lower price-to-earnings ratio than Palvella Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Palvella Therapeutics$42.81M52.67-$41.72M-$4.17N/A
Spyre Therapeutics$890K9,903.62-$155.20M-$2.08N/A

Summary

Palvella Therapeutics beats Spyre Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Vaxcyte?

Palvella Therapeutics (NASDAQ:PVLA) and Vaxcyte (NASDAQ:PCVX) are both mid-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their dividends, risk, analyst recommendations, valuation, institutional ownership, profitability, media sentiment and earnings.

Vaxcyte's return on equity of -32.51% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Palvella TherapeuticsN/A -56.87% -42.50%
Vaxcyte N/A -32.51%-29.51%

Palvella Therapeutics has higher revenue and earnings than Vaxcyte. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Vaxcyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Palvella Therapeutics$42.81M52.67-$41.72M-$4.17N/A
VaxcyteN/AN/A-$766.63M-$6.88N/A

40.1% of Palvella Therapeutics shares are owned by institutional investors. Comparatively, 96.8% of Vaxcyte shares are owned by institutional investors. 17.2% of Palvella Therapeutics shares are owned by insiders. Comparatively, 3.3% of Vaxcyte shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Palvella Therapeutics has a beta of -0.2, suggesting that its share price is 120% less volatile than the broader market. Comparatively, Vaxcyte has a beta of 1.22, suggesting that its share price is 22% more volatile than the broader market.

Palvella Therapeutics currently has a consensus target price of $199.53, suggesting a potential upside of 26.90%. Vaxcyte has a consensus target price of $86.00, suggesting a potential upside of 53.02%. Given Vaxcyte's higher possible upside, analysts clearly believe Vaxcyte is more favorable than Palvella Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
Vaxcyte
2 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.44

In the previous week, Palvella Therapeutics had 5 more articles in the media than Vaxcyte. MarketBeat recorded 9 mentions for Palvella Therapeutics and 4 mentions for Vaxcyte. Vaxcyte's average media sentiment score of 0.95 beat Palvella Therapeutics' score of 0.92 indicating that Vaxcyte is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Palvella Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vaxcyte
3 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Palvella Therapeutics beats Vaxcyte on 8 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Immunovant?

Immunovant (NASDAQ:IMVT) and Palvella Therapeutics (NASDAQ:PVLA) are both mid-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their profitability, valuation, risk, dividends, institutional ownership, media sentiment, analyst recommendations and earnings.

In the previous week, Palvella Therapeutics had 7 more articles in the media than Immunovant. MarketBeat recorded 9 mentions for Palvella Therapeutics and 2 mentions for Immunovant. Immunovant's average media sentiment score of 0.99 beat Palvella Therapeutics' score of 0.92 indicating that Immunovant is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Immunovant
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Palvella Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Immunovant presently has a consensus target price of $39.70, indicating a potential downside of 1.39%. Palvella Therapeutics has a consensus target price of $199.53, indicating a potential upside of 26.90%. Given Palvella Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Palvella Therapeutics is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Immunovant
1 Sell rating(s)
4 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.45
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

Palvella Therapeutics has higher revenue and earnings than Immunovant. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Immunovant, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ImmunovantN/AN/A-$505.61M-$2.78N/A
Palvella Therapeutics$42.81M52.67-$41.72M-$4.17N/A

Palvella Therapeutics' return on equity of -56.87% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunovantN/A -65.66% -59.88%
Palvella Therapeutics N/A -56.87%-42.50%

Immunovant has a beta of 0.76, indicating that its stock price is 24% less volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.2, indicating that its stock price is 120% less volatile than the broader market.

47.1% of Immunovant shares are held by institutional investors. Comparatively, 40.1% of Palvella Therapeutics shares are held by institutional investors. 1.8% of Immunovant shares are held by company insiders. Comparatively, 17.2% of Palvella Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Summary

Palvella Therapeutics beats Immunovant on 10 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PVLA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PVLA vs. The Competition

MetricPalvella TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$2.25B$3.69B$6.86B$12.27B
Dividend YieldN/A2.17%2.67%9.36%
P/E Ratio-37.7121.2127.2523.92
Price / Sales52.67304.52584.48113.62
Price / CashN/A60.3129.0548.09
Price / Book66.638.2810.706.18
Net Income-$41.72M$23.81M$3.59B$331.89M
7 Day Performance7.68%-1.34%-1.00%-1.22%
1 Month Performance39.03%2.68%1.66%-1.30%
1 Year Performance432.84%45.93%25.64%17.74%

Palvella Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PVLA
Palvella Therapeutics
2.8405 of 5 stars
$157.24
flat
$199.53
+26.9%
+432.8%$2.25B$42.81MN/AN/A
TGTX
TG Therapeutics
3.065 of 5 stars
$54.93
-2.6%
$53.33
-2.9%
+44.7%$8.41B$616.29M19.21290
APGE
Apogee Therapeutics
1.8971 of 5 stars
$134.08
-0.2%
$121.25
-9.6%
+240.9%$8.30BN/AN/A91
SYRE
Spyre Therapeutics
1.4324 of 5 stars
$94.12
-7.8%
$101.42
+7.8%
+515.3%$8.28BN/AN/A73
PCVX
Vaxcyte
2.7271 of 5 stars
$56.04
-1.2%
$86.00
+53.5%
+55.2%$8.09BN/AN/A160

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This page (NASDAQ:PVLA) was last updated on 7/20/2026 by MarketBeat.com Staff.
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