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Palvella Therapeutics (PVLA) Competitors

Palvella Therapeutics logo
$151.69 +3.48 (+2.35%)
As of 03:29 PM Eastern
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PVLA vs. PCVX, SYRE, RYTM, ABVX, and MIRM

Should you buy Palvella Therapeutics stock or one of its competitors? MarketBeat compares Palvella Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Palvella Therapeutics include Vaxcyte (PCVX), Spyre Therapeutics (SYRE), Rhythm Pharmaceuticals (RYTM), Abivax (ABVX), and Mirum Pharmaceuticals (MIRM). These companies are all part of the "pharmaceutical products" industry.

How does Palvella Therapeutics compare to Vaxcyte?

Vaxcyte (NASDAQ:PCVX) and Palvella Therapeutics (NASDAQ:PVLA) are both mid-cap medical companies, but which is the superior investment? We will compare the two companies based on the strength of their dividends, earnings, profitability, analyst recommendations, risk, media sentiment, institutional ownership and valuation.

In the previous week, Palvella Therapeutics had 1 more articles in the media than Vaxcyte. MarketBeat recorded 8 mentions for Palvella Therapeutics and 7 mentions for Vaxcyte. Palvella Therapeutics' average media sentiment score of 0.61 beat Vaxcyte's score of -0.25 indicating that Palvella Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vaxcyte
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Palvella Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Vaxcyte has a beta of 1.24, indicating that its share price is 24% more volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.14, indicating that its share price is 114% less volatile than the broader market.

Palvella Therapeutics has higher revenue and earnings than Vaxcyte. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Vaxcyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
VaxcyteN/AN/A-$766.63M-$6.88N/A
Palvella Therapeutics$42.81M50.81-$41.72M-$4.17N/A

Vaxcyte's return on equity of -32.51% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
VaxcyteN/A -32.51% -29.51%
Palvella Therapeutics N/A -56.87%-42.50%

Vaxcyte presently has a consensus target price of $86.00, indicating a potential upside of 50.17%. Palvella Therapeutics has a consensus target price of $199.53, indicating a potential upside of 31.54%. Given Vaxcyte's higher possible upside, research analysts plainly believe Vaxcyte is more favorable than Palvella Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vaxcyte
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.63
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

96.8% of Vaxcyte shares are held by institutional investors. Comparatively, 40.1% of Palvella Therapeutics shares are held by institutional investors. 3.3% of Vaxcyte shares are held by insiders. Comparatively, 17.2% of Palvella Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Summary

Palvella Therapeutics beats Vaxcyte on 9 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Spyre Therapeutics?

Spyre Therapeutics (NASDAQ:SYRE) and Palvella Therapeutics (NASDAQ:PVLA) are both mid-cap medical companies, but which is the better stock? We will contrast the two companies based on the strength of their earnings, institutional ownership, valuation, risk, dividends, profitability, media sentiment and analyst recommendations.

Spyre Therapeutics presently has a consensus price target of $95.83, suggesting a potential upside of 6.52%. Palvella Therapeutics has a consensus price target of $199.53, suggesting a potential upside of 31.54%. Given Palvella Therapeutics' higher possible upside, analysts plainly believe Palvella Therapeutics is more favorable than Spyre Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Spyre Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
2 Strong Buy rating(s)
3.00
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

Palvella Therapeutics has higher revenue and earnings than Spyre Therapeutics. Spyre Therapeutics is trading at a lower price-to-earnings ratio than Palvella Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Spyre Therapeutics$890K8,778.74-$155.20M-$2.08N/A
Palvella Therapeutics$42.81M50.81-$41.72M-$4.17N/A

Spyre Therapeutics' return on equity of -42.88% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Spyre TherapeuticsN/A -42.88% -27.76%
Palvella Therapeutics N/A -56.87%-42.50%

Spyre Therapeutics has a beta of 3.05, indicating that its share price is 205% more volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.14, indicating that its share price is 114% less volatile than the broader market.

80.4% of Spyre Therapeutics shares are owned by institutional investors. Comparatively, 40.1% of Palvella Therapeutics shares are owned by institutional investors. 15.7% of Spyre Therapeutics shares are owned by company insiders. Comparatively, 17.2% of Palvella Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

In the previous week, Spyre Therapeutics had 2 more articles in the media than Palvella Therapeutics. MarketBeat recorded 10 mentions for Spyre Therapeutics and 8 mentions for Palvella Therapeutics. Palvella Therapeutics' average media sentiment score of 0.61 beat Spyre Therapeutics' score of 0.44 indicating that Palvella Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Spyre Therapeutics
2 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Palvella Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Spyre Therapeutics beats Palvella Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Palvella Therapeutics compare to Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Palvella Therapeutics (NASDAQ:PVLA) are both mid-cap medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their media sentiment, earnings, profitability, risk, analyst recommendations, valuation, institutional ownership and dividends.

Palvella Therapeutics has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -93.33%. Palvella Therapeutics' return on equity of -56.87% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-93.33% -203.25% -44.99%
Palvella Therapeutics N/A -56.87%-42.50%

Palvella Therapeutics has lower revenue, but higher earnings than Rhythm Pharmaceuticals. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Rhythm Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$217.17M34.31-$196.54M-$3.13N/A
Palvella Therapeutics$42.81M50.81-$41.72M-$4.17N/A

40.1% of Palvella Therapeutics shares are held by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are held by company insiders. Comparatively, 17.2% of Palvella Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

In the previous week, Palvella Therapeutics had 3 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 8 mentions for Palvella Therapeutics and 5 mentions for Rhythm Pharmaceuticals. Palvella Therapeutics' average media sentiment score of 0.61 beat Rhythm Pharmaceuticals' score of 0.61 indicating that Palvella Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Palvella Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Rhythm Pharmaceuticals currently has a consensus price target of $133.13, indicating a potential upside of 22.44%. Palvella Therapeutics has a consensus price target of $199.53, indicating a potential upside of 31.54%. Given Palvella Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Palvella Therapeutics is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.83
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

Rhythm Pharmaceuticals has a beta of 1.92, indicating that its stock price is 92% more volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.14, indicating that its stock price is 114% less volatile than the broader market.

Summary

Palvella Therapeutics beats Rhythm Pharmaceuticals on 11 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Abivax?

Palvella Therapeutics (NASDAQ:PVLA) and Abivax (NASDAQ:ABVX) are both mid-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their profitability, media sentiment, valuation, earnings, analyst recommendations, dividends, institutional ownership and risk.

40.1% of Palvella Therapeutics shares are owned by institutional investors. Comparatively, 47.9% of Abivax shares are owned by institutional investors. 17.2% of Palvella Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Palvella Therapeutics' return on equity of -56.87% beat Abivax's return on equity.

Company Net Margins Return on Equity Return on Assets
Palvella TherapeuticsN/A -56.87% -42.50%
Abivax N/A -99.02%-70.26%

Palvella Therapeutics has higher revenue and earnings than Abivax. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Abivax, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Palvella Therapeutics$42.81M50.81-$41.72M-$4.17N/A
AbivaxN/AN/A-$380.27M-$5.21N/A

Palvella Therapeutics has a beta of -0.14, suggesting that its share price is 114% less volatile than the broader market. Comparatively, Abivax has a beta of 0.69, suggesting that its share price is 31% less volatile than the broader market.

In the previous week, Palvella Therapeutics had 6 more articles in the media than Abivax. MarketBeat recorded 8 mentions for Palvella Therapeutics and 2 mentions for Abivax. Abivax's average media sentiment score of 0.84 beat Palvella Therapeutics' score of 0.61 indicating that Abivax is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Palvella Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Abivax
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Palvella Therapeutics currently has a consensus target price of $199.53, indicating a potential upside of 31.54%. Abivax has a consensus target price of $130.08, indicating a potential upside of 35.69%. Given Abivax's higher possible upside, analysts clearly believe Abivax is more favorable than Palvella Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
Abivax
1 Sell rating(s)
2 Hold rating(s)
12 Buy rating(s)
0 Strong Buy rating(s)
2.73

Summary

Palvella Therapeutics beats Abivax on 10 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Mirum Pharmaceuticals?

Palvella Therapeutics (NASDAQ:PVLA) and Mirum Pharmaceuticals (NASDAQ:MIRM) are both mid-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, dividends, media sentiment, institutional ownership, earnings, profitability, valuation and risk.

In the previous week, Palvella Therapeutics had 4 more articles in the media than Mirum Pharmaceuticals. MarketBeat recorded 8 mentions for Palvella Therapeutics and 4 mentions for Mirum Pharmaceuticals. Mirum Pharmaceuticals' average media sentiment score of 1.18 beat Palvella Therapeutics' score of 0.61 indicating that Mirum Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Palvella Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Mirum Pharmaceuticals
1 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Palvella Therapeutics has a beta of -0.14, meaning that its stock price is 114% less volatile than the broader market. Comparatively, Mirum Pharmaceuticals has a beta of 0.5, meaning that its stock price is 50% less volatile than the broader market.

40.1% of Palvella Therapeutics shares are held by institutional investors. 17.2% of Palvella Therapeutics shares are held by insiders. Comparatively, 8.3% of Mirum Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Palvella Therapeutics presently has a consensus price target of $199.53, suggesting a potential upside of 31.54%. Mirum Pharmaceuticals has a consensus price target of $139.80, suggesting a potential upside of 13.54%. Given Palvella Therapeutics' stronger consensus rating and higher possible upside, equities analysts clearly believe Palvella Therapeutics is more favorable than Mirum Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
Mirum Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.93

Mirum Pharmaceuticals has higher revenue and earnings than Palvella Therapeutics. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Mirum Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Palvella Therapeutics$42.81M50.81-$41.72M-$4.17N/A
Mirum Pharmaceuticals$521.31M14.40-$23.36M-$13.61N/A

Palvella Therapeutics has a net margin of 0.00% compared to Mirum Pharmaceuticals' net margin of -140.24%. Mirum Pharmaceuticals' return on equity of -11.28% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Palvella TherapeuticsN/A -56.87% -42.50%
Mirum Pharmaceuticals -140.24%-11.28%-3.84%

Summary

Palvella Therapeutics beats Mirum Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PVLA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PVLA vs. The Competition

MetricPalvella TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$2.17B$3.65B$6.84B$12.43B
Dividend YieldN/A2.22%2.67%6.11%
P/E Ratio-36.2921.2125.8224.32
Price / Sales50.81343.70549.62102.11
Price / CashN/A62.1029.0936.93
Price / Book64.288.6610.986.49
Net Income-$41.72M$23.92M$3.58B$336.61M
7 Day Performance27.64%3.71%2.85%0.76%
1 Month Performance28.05%1.20%0.52%-0.48%
1 Year Performance587.00%68.53%36.24%30.79%

Palvella Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PVLA
Palvella Therapeutics
3.0177 of 5 stars
$151.69
+2.3%
$199.53
+31.5%
+571.2%$2.17B$42.81MN/AN/A
PCVX
Vaxcyte
2.0222 of 5 stars
$53.62
-0.5%
$86.00
+60.4%
+73.5%$7.74BN/AN/A160
SYRE
Spyre Therapeutics
1.6779 of 5 stars
$88.67
+2.8%
$95.83
+8.1%
+477.5%$7.70B$890KN/A73
RYTM
Rhythm Pharmaceuticals
2.5856 of 5 stars
$108.39
+0.8%
$133.13
+22.8%
+75.1%$7.43B$189.76MN/A140
ABVX
Abivax
2.947 of 5 stars
$92.26
-0.3%
$130.08
+41.0%
+1,217.6%$7.36BN/AN/A61

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This page (NASDAQ:PVLA) was last updated on 6/29/2026 by MarketBeat.com Staff.
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