Go Pro

Palvella Therapeutics (PVLA) Competitors

Palvella Therapeutics logo
$157.77 +2.84 (+1.83%)
Closing price 08/7/2026 04:00 PM Eastern
Extended Trading
$157.78 +0.01 (+0.01%)
As of 08/7/2026 07:34 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PVLA vs. KYMR, PCVX, APGE, IMVT, and RYTM

Should you buy Palvella Therapeutics stock or one of its competitors? MarketBeat compares Palvella Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Palvella Therapeutics include Kymera Therapeutics (KYMR), Vaxcyte (PCVX), Apogee Therapeutics (APGE), Immunovant (IMVT), and Rhythm Pharmaceuticals (RYTM). These companies are all part of the "biotechnology" industry.

How does Palvella Therapeutics compare to Kymera Therapeutics?

Kymera Therapeutics (NASDAQ:KYMR) and Palvella Therapeutics (NASDAQ:PVLA) are both mid-cap healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their profitability, earnings, dividends, media sentiment, risk, valuation, institutional ownership and analyst recommendations.

Kymera Therapeutics has a beta of 1.95, meaning that its share price is 95% more volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.17, meaning that its share price is 117% less volatile than the broader market.

Palvella Therapeutics has a net margin of 0.00% compared to Kymera Therapeutics' net margin of -285.33%. Kymera Therapeutics' return on equity of -21.82% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Kymera Therapeutics-285.33% -21.82% -19.66%
Palvella Therapeutics N/A -47.84%-38.33%

In the previous week, Kymera Therapeutics had 6 more articles in the media than Palvella Therapeutics. MarketBeat recorded 27 mentions for Kymera Therapeutics and 21 mentions for Palvella Therapeutics. Kymera Therapeutics' average media sentiment score of -0.13 beat Palvella Therapeutics' score of -0.34 indicating that Kymera Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Kymera Therapeutics
3 Very Positive mention(s)
2 Positive mention(s)
5 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral
Palvella Therapeutics
3 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Palvella Therapeutics has lower revenue, but higher earnings than Kymera Therapeutics. Kymera Therapeutics is trading at a lower price-to-earnings ratio than Palvella Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Kymera Therapeutics$105M85.15-$311.35M-$3.24N/A
Palvella Therapeutics$42.81M53.11-$41.72M-$4.83N/A

40.1% of Palvella Therapeutics shares are held by institutional investors. 16.0% of Kymera Therapeutics shares are held by company insiders. Comparatively, 17.2% of Palvella Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Kymera Therapeutics currently has a consensus price target of $125.65, suggesting a potential upside of 16.86%. Palvella Therapeutics has a consensus price target of $209.14, suggesting a potential upside of 32.56%. Given Palvella Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Palvella Therapeutics is more favorable than Kymera Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Kymera Therapeutics
1 Sell rating(s)
2 Hold rating(s)
20 Buy rating(s)
0 Strong Buy rating(s)
2.83
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00

Summary

Kymera Therapeutics beats Palvella Therapeutics on 9 of the 17 factors compared between the two stocks.

How does Palvella Therapeutics compare to Vaxcyte?

Vaxcyte (NASDAQ:PCVX) and Palvella Therapeutics (NASDAQ:PVLA) are both mid-cap healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their profitability, earnings, risk, institutional ownership, valuation, analyst recommendations, dividends and media sentiment.

Vaxcyte has a beta of 1.23, meaning that its share price is 23% more volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.17, meaning that its share price is 117% less volatile than the broader market.

96.8% of Vaxcyte shares are held by institutional investors. Comparatively, 40.1% of Palvella Therapeutics shares are held by institutional investors. 3.3% of Vaxcyte shares are held by company insiders. Comparatively, 17.2% of Palvella Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Palvella Therapeutics has higher revenue and earnings than Vaxcyte. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Vaxcyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
VaxcyteN/AN/A-$766.63M-$7.63N/A
Palvella Therapeutics$42.81M53.11-$41.72M-$4.83N/A

Vaxcyte presently has a consensus target price of $86.00, suggesting a potential upside of 48.10%. Palvella Therapeutics has a consensus target price of $209.14, suggesting a potential upside of 32.56%. Given Vaxcyte's higher probable upside, equities research analysts clearly believe Vaxcyte is more favorable than Palvella Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Vaxcyte
2 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.38
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00

Vaxcyte's return on equity of -37.56% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
VaxcyteN/A -37.56% -33.62%
Palvella Therapeutics N/A -47.84%-38.33%

In the previous week, Palvella Therapeutics had 2 more articles in the media than Vaxcyte. MarketBeat recorded 21 mentions for Palvella Therapeutics and 19 mentions for Vaxcyte. Vaxcyte's average media sentiment score of 0.78 beat Palvella Therapeutics' score of -0.34 indicating that Vaxcyte is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Vaxcyte
9 Very Positive mention(s)
2 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Palvella Therapeutics
3 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Palvella Therapeutics beats Vaxcyte on 8 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Apogee Therapeutics?

Apogee Therapeutics (NASDAQ:APGE) and Palvella Therapeutics (NASDAQ:PVLA) are both mid-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their risk, media sentiment, profitability, analyst recommendations, institutional ownership, earnings, valuation and dividends.

Apogee Therapeutics' return on equity of -32.64% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Apogee TherapeuticsN/A -32.64% -31.25%
Palvella Therapeutics N/A -47.84%-38.33%

In the previous week, Palvella Therapeutics had 11 more articles in the media than Apogee Therapeutics. MarketBeat recorded 21 mentions for Palvella Therapeutics and 10 mentions for Apogee Therapeutics. Apogee Therapeutics' average media sentiment score of 0.83 beat Palvella Therapeutics' score of -0.34 indicating that Apogee Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Apogee Therapeutics
5 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Palvella Therapeutics
3 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Apogee Therapeutics has a beta of 0.34, indicating that its stock price is 66% less volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.17, indicating that its stock price is 117% less volatile than the broader market.

79.0% of Apogee Therapeutics shares are owned by institutional investors. Comparatively, 40.1% of Palvella Therapeutics shares are owned by institutional investors. 24.3% of Apogee Therapeutics shares are owned by company insiders. Comparatively, 17.2% of Palvella Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Palvella Therapeutics has higher revenue and earnings than Apogee Therapeutics. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Apogee Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Apogee TherapeuticsN/AN/A-$255.84M-$4.33N/A
Palvella Therapeutics$42.81M53.11-$41.72M-$4.83N/A

Apogee Therapeutics currently has a consensus target price of $121.25, suggesting a potential downside of 10.08%. Palvella Therapeutics has a consensus target price of $209.14, suggesting a potential upside of 32.56%. Given Palvella Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Palvella Therapeutics is more favorable than Apogee Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Apogee Therapeutics
1 Sell rating(s)
15 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.24
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00

Summary

Apogee Therapeutics beats Palvella Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Immunovant?

Immunovant (NASDAQ:IMVT) and Palvella Therapeutics (NASDAQ:PVLA) are both mid-cap healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their dividends, risk, valuation, earnings, institutional ownership, analyst recommendations, profitability and media sentiment.

Immunovant has a beta of 0.77, meaning that its stock price is 23% less volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.17, meaning that its stock price is 117% less volatile than the broader market.

In the previous week, Palvella Therapeutics had 12 more articles in the media than Immunovant. MarketBeat recorded 21 mentions for Palvella Therapeutics and 9 mentions for Immunovant. Immunovant's average media sentiment score of 0.39 beat Palvella Therapeutics' score of -0.34 indicating that Immunovant is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Immunovant
3 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Palvella Therapeutics
3 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Palvella Therapeutics' return on equity of -47.84% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunovantN/A -68.46% -62.28%
Palvella Therapeutics N/A -47.84%-38.33%

Immunovant currently has a consensus target price of $44.00, suggesting a potential upside of 10.14%. Palvella Therapeutics has a consensus target price of $209.14, suggesting a potential upside of 32.56%. Given Palvella Therapeutics' stronger consensus rating and higher possible upside, analysts clearly believe Palvella Therapeutics is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Immunovant
1 Sell rating(s)
3 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.50
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00

47.1% of Immunovant shares are held by institutional investors. Comparatively, 40.1% of Palvella Therapeutics shares are held by institutional investors. 1.9% of Immunovant shares are held by company insiders. Comparatively, 17.2% of Palvella Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Palvella Therapeutics has higher revenue and earnings than Immunovant. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Immunovant, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ImmunovantN/AN/A-$505.61M-$2.82N/A
Palvella Therapeutics$42.81M53.11-$41.72M-$4.83N/A

Summary

Palvella Therapeutics beats Immunovant on 10 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Palvella Therapeutics (NASDAQ:PVLA) are both mid-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their analyst recommendations, valuation, institutional ownership, dividends, media sentiment, profitability, earnings and risk.

Rhythm Pharmaceuticals presently has a consensus price target of $142.44, indicating a potential upside of 23.18%. Palvella Therapeutics has a consensus price target of $209.14, indicating a potential upside of 32.56%. Given Palvella Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Palvella Therapeutics is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
15 Buy rating(s)
0 Strong Buy rating(s)
2.78
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00

Rhythm Pharmaceuticals has a beta of 1.92, indicating that its share price is 92% more volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.17, indicating that its share price is 117% less volatile than the broader market.

In the previous week, Rhythm Pharmaceuticals had 3 more articles in the media than Palvella Therapeutics. MarketBeat recorded 24 mentions for Rhythm Pharmaceuticals and 21 mentions for Palvella Therapeutics. Rhythm Pharmaceuticals' average media sentiment score of 0.53 beat Palvella Therapeutics' score of -0.34 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
5 Very Positive mention(s)
1 Positive mention(s)
12 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive
Palvella Therapeutics
3 Very Positive mention(s)
4 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Palvella Therapeutics has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -85.59%. Palvella Therapeutics' return on equity of -47.84% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
Palvella Therapeutics N/A -47.84%-38.33%

Palvella Therapeutics has lower revenue, but higher earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Palvella Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$239.92M33.03-$196.54M-$3.11N/A
Palvella Therapeutics$42.81M53.11-$41.72M-$4.83N/A

40.1% of Palvella Therapeutics shares are held by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are held by company insiders. Comparatively, 17.2% of Palvella Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Summary

Palvella Therapeutics beats Rhythm Pharmaceuticals on 11 of the 17 factors compared between the two stocks.

Get Palvella Therapeutics News Delivered to You Automatically

Sign up to receive the latest news and ratings for PVLA and its competitors with MarketBeat's FREE daily newsletter.

Subscribe Now
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.

New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PVLA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Skip Chart

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Skip Chart

PVLA vs. The Competition

MetricPalvella TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$2.27B$3.69B$7.02B$13.01B
Dividend YieldN/A3.76%2.58%10.20%
P/E Ratio-32.669.02271.1125.19
Price / Sales53.111,255.27581.1376.02
Price / CashN/A102.3571.8150.72
Price / Book10.4818.1013.256.22
Net Income-$41.72M-$13.25M$3.45B$342.66M
7 Day Performance13.47%6.24%4.67%4.41%
1 Month Performance4.46%-3.50%-1.28%-1.10%
1 Year Performance285.75%61.28%77.33%23.99%

Palvella Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PVLA
Palvella Therapeutics
2.9938 of 5 stars
$157.77
+1.8%
$209.14
+32.6%
+285.7%$2.27B$42.81MN/AN/A
KYMR
Kymera Therapeutics
1.6934 of 5 stars
$106.41
+0.9%
$125.65
+18.1%
+164.7%$8.75B$51.48MN/A170
PCVX
Vaxcyte
2.7413 of 5 stars
$58.89
+5.3%
$86.00
+46.0%
+94.2%$8.50BN/AN/A160
APGE
Apogee Therapeutics
1.87 of 5 stars
$134.49
+0.2%
$121.25
-9.8%
+281.0%$8.32BN/AN/A91
IMVT
Immunovant
1.7246 of 5 stars
$39.74
+1.2%
$44.00
+10.7%
+158.4%$8.20BN/AN/A120

Related Companies and Tools


This page (NASDAQ:PVLA) was last updated on 8/9/2026 by MarketBeat.com Staff.
From Our Partners