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Palvella Therapeutics (PVLA) Competitors

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$105.25 -3.42 (-3.15%)
Closing price 04:00 PM Eastern
Extended Trading
$105.24 -0.01 (-0.01%)
As of 04:10 PM Eastern
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PVLA vs. LNTH, PTGX, RYTM, SYRE, and COGT

Should you buy Palvella Therapeutics stock or one of its competitors? MarketBeat compares Palvella Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Palvella Therapeutics include Lantheus (LNTH), Protagonist Therapeutics (PTGX), Rhythm Pharmaceuticals (RYTM), Spyre Therapeutics (SYRE), and Cogent Biosciences (COGT). These companies are all part of the "pharmaceutical products" industry.

How does Palvella Therapeutics compare to Lantheus?

Lantheus (NASDAQ:LNTH) and Palvella Therapeutics (NASDAQ:PVLA) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their earnings, risk, media sentiment, analyst recommendations, institutional ownership, dividends, valuation and profitability.

99.1% of Lantheus shares are held by institutional investors. Comparatively, 40.1% of Palvella Therapeutics shares are held by institutional investors. 1.7% of Lantheus shares are held by company insiders. Comparatively, 20.5% of Palvella Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Lantheus has higher revenue and earnings than Palvella Therapeutics. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Lantheus, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lantheus$1.55B4.21$233.56M$4.1524.10
Palvella Therapeutics$42.81M35.26-$41.72M-$4.17N/A

Lantheus has a beta of -0.03, indicating that its stock price is 103% less volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.14, indicating that its stock price is 114% less volatile than the broader market.

Lantheus has a net margin of 18.05% compared to Palvella Therapeutics' net margin of 0.00%. Lantheus' return on equity of 29.32% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Lantheus18.05% 29.32% 15.00%
Palvella Therapeutics N/A -56.87%-42.50%

In the previous week, Palvella Therapeutics had 3 more articles in the media than Lantheus. MarketBeat recorded 7 mentions for Palvella Therapeutics and 4 mentions for Lantheus. Lantheus' average media sentiment score of 0.54 beat Palvella Therapeutics' score of 0.53 indicating that Lantheus is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lantheus
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Palvella Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Lantheus currently has a consensus price target of $101.86, suggesting a potential upside of 1.85%. Palvella Therapeutics has a consensus price target of $199.53, suggesting a potential upside of 89.58%. Given Palvella Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Palvella Therapeutics is more favorable than Lantheus.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lantheus
0 Sell rating(s)
3 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.73
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

Summary

Lantheus beats Palvella Therapeutics on 10 of the 17 factors compared between the two stocks.

How does Palvella Therapeutics compare to Protagonist Therapeutics?

Palvella Therapeutics (NASDAQ:PVLA) and Protagonist Therapeutics (NASDAQ:PTGX) are both medical companies, but which is the superior business? We will compare the two businesses based on the strength of their risk, profitability, dividends, institutional ownership, valuation, analyst recommendations, earnings and media sentiment.

Palvella Therapeutics has a net margin of 0.00% compared to Protagonist Therapeutics' net margin of -154.88%. Protagonist Therapeutics' return on equity of -17.76% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Palvella TherapeuticsN/A -56.87% -42.50%
Protagonist Therapeutics -154.88%-17.76%-16.47%

40.1% of Palvella Therapeutics shares are owned by institutional investors. Comparatively, 98.6% of Protagonist Therapeutics shares are owned by institutional investors. 20.5% of Palvella Therapeutics shares are owned by company insiders. Comparatively, 5.2% of Protagonist Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

In the previous week, Palvella Therapeutics had 3 more articles in the media than Protagonist Therapeutics. MarketBeat recorded 7 mentions for Palvella Therapeutics and 4 mentions for Protagonist Therapeutics. Palvella Therapeutics' average media sentiment score of 0.53 beat Protagonist Therapeutics' score of 0.43 indicating that Palvella Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Palvella Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Protagonist Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Palvella Therapeutics has a beta of -0.14, indicating that its share price is 114% less volatile than the broader market. Comparatively, Protagonist Therapeutics has a beta of 1.85, indicating that its share price is 85% more volatile than the broader market.

Palvella Therapeutics presently has a consensus target price of $199.53, suggesting a potential upside of 89.58%. Protagonist Therapeutics has a consensus target price of $115.21, suggesting a potential upside of 17.53%. Given Palvella Therapeutics' stronger consensus rating and higher possible upside, equities analysts plainly believe Palvella Therapeutics is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
Protagonist Therapeutics
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.88

Palvella Therapeutics has higher earnings, but lower revenue than Protagonist Therapeutics. Protagonist Therapeutics is trading at a lower price-to-earnings ratio than Palvella Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Palvella Therapeutics$42.81M35.26-$41.72M-$4.17N/A
Protagonist Therapeutics$74.06M85.12-$130.15M-$1.81N/A

Summary

Palvella Therapeutics beats Protagonist Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Palvella Therapeutics compare to Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Palvella Therapeutics (NASDAQ:PVLA) are both medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, dividends, valuation, earnings, institutional ownership, risk, analyst recommendations and profitability.

Palvella Therapeutics has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -93.33%. Palvella Therapeutics' return on equity of -56.87% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-93.33% -203.25% -44.99%
Palvella Therapeutics N/A -56.87%-42.50%

Rhythm Pharmaceuticals has a beta of 1.91, meaning that its share price is 91% more volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.14, meaning that its share price is 114% less volatile than the broader market.

40.1% of Palvella Therapeutics shares are held by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are held by insiders. Comparatively, 20.5% of Palvella Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Rhythm Pharmaceuticals currently has a consensus target price of $131.81, suggesting a potential upside of 53.40%. Palvella Therapeutics has a consensus target price of $199.53, suggesting a potential upside of 89.58%. Given Palvella Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Palvella Therapeutics is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
2 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.83
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

Palvella Therapeutics has lower revenue, but higher earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Palvella Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$217.17M27.12-$196.54M-$3.13N/A
Palvella Therapeutics$42.81M35.26-$41.72M-$4.17N/A

In the previous week, Palvella Therapeutics had 4 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 7 mentions for Palvella Therapeutics and 3 mentions for Rhythm Pharmaceuticals. Palvella Therapeutics' average media sentiment score of 0.53 beat Rhythm Pharmaceuticals' score of 0.00 indicating that Palvella Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Rhythm Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Palvella Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Palvella Therapeutics beats Rhythm Pharmaceuticals on 12 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Spyre Therapeutics?

Palvella Therapeutics (NASDAQ:PVLA) and Spyre Therapeutics (NASDAQ:SYRE) are both medical companies, but which is the better business? We will compare the two businesses based on the strength of their analyst recommendations, profitability, dividends, earnings, valuation, institutional ownership, media sentiment and risk.

In the previous week, Spyre Therapeutics had 4 more articles in the media than Palvella Therapeutics. MarketBeat recorded 11 mentions for Spyre Therapeutics and 7 mentions for Palvella Therapeutics. Palvella Therapeutics' average media sentiment score of 0.53 beat Spyre Therapeutics' score of 0.01 indicating that Palvella Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Palvella Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Spyre Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

40.1% of Palvella Therapeutics shares are owned by institutional investors. Comparatively, 80.4% of Spyre Therapeutics shares are owned by institutional investors. 20.5% of Palvella Therapeutics shares are owned by company insiders. Comparatively, 15.7% of Spyre Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Spyre Therapeutics' return on equity of -42.88% beat Palvella Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Palvella TherapeuticsN/A -56.87% -42.50%
Spyre Therapeutics N/A -42.88%-27.76%

Palvella Therapeutics has higher revenue and earnings than Spyre Therapeutics. Spyre Therapeutics is trading at a lower price-to-earnings ratio than Palvella Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Palvella Therapeutics$42.81M35.26-$41.72M-$4.17N/A
Spyre TherapeuticsN/AN/A-$155.20M-$2.08N/A

Palvella Therapeutics currently has a consensus price target of $199.53, indicating a potential upside of 89.58%. Spyre Therapeutics has a consensus price target of $91.33, indicating a potential upside of 26.85%. Given Palvella Therapeutics' higher probable upside, research analysts clearly believe Palvella Therapeutics is more favorable than Spyre Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94
Spyre Therapeutics
1 Sell rating(s)
0 Hold rating(s)
10 Buy rating(s)
2 Strong Buy rating(s)
3.00

Palvella Therapeutics has a beta of -0.14, indicating that its stock price is 114% less volatile than the broader market. Comparatively, Spyre Therapeutics has a beta of 3.05, indicating that its stock price is 205% more volatile than the broader market.

Summary

Spyre Therapeutics beats Palvella Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Palvella Therapeutics compare to Cogent Biosciences?

Cogent Biosciences (NASDAQ:COGT) and Palvella Therapeutics (NASDAQ:PVLA) are both medical companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, dividends, profitability, earnings, analyst recommendations, institutional ownership, valuation and media sentiment.

Cogent Biosciences presently has a consensus target price of $43.73, suggesting a potential upside of 40.33%. Palvella Therapeutics has a consensus target price of $199.53, suggesting a potential upside of 89.58%. Given Palvella Therapeutics' stronger consensus rating and higher probable upside, analysts clearly believe Palvella Therapeutics is more favorable than Cogent Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cogent Biosciences
1 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
2 Strong Buy rating(s)
2.86
Palvella Therapeutics
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
1 Strong Buy rating(s)
2.94

Palvella Therapeutics' return on equity of -56.87% beat Cogent Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Cogent BiosciencesN/A -104.27% -54.64%
Palvella Therapeutics N/A -56.87%-42.50%

Palvella Therapeutics has higher revenue and earnings than Cogent Biosciences. Palvella Therapeutics is trading at a lower price-to-earnings ratio than Cogent Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cogent BiosciencesN/AN/A-$328.94M-$2.17N/A
Palvella Therapeutics$42.81M35.26-$41.72M-$4.17N/A

40.1% of Palvella Therapeutics shares are owned by institutional investors. 6.6% of Cogent Biosciences shares are owned by insiders. Comparatively, 20.5% of Palvella Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Cogent Biosciences has a beta of 0.34, meaning that its stock price is 66% less volatile than the broader market. Comparatively, Palvella Therapeutics has a beta of -0.14, meaning that its stock price is 114% less volatile than the broader market.

In the previous week, Palvella Therapeutics had 5 more articles in the media than Cogent Biosciences. MarketBeat recorded 7 mentions for Palvella Therapeutics and 2 mentions for Cogent Biosciences. Cogent Biosciences' average media sentiment score of 0.68 beat Palvella Therapeutics' score of 0.53 indicating that Cogent Biosciences is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Cogent Biosciences
0 Very Positive mention(s)
2 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Palvella Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Palvella Therapeutics beats Cogent Biosciences on 10 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PVLA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PVLA vs. The Competition

MetricPalvella TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$1.51B$3.30B$6.43B$12.05B
Dividend YieldN/A2.31%2.67%5.56%
P/E Ratio-25.2418.9323.7523.75
Price / Sales35.26176.22479.7984.65
Price / CashN/A51.4526.9937.25
Price / Book44.608.0410.286.78
Net Income-$41.72M$23.89M$3.57B$337.51M
7 Day Performance-6.52%-6.04%-1.45%-2.72%
1 Month Performance-13.22%2.72%3.25%1.87%
1 Year Performance314.37%36.16%23.34%26.60%

Palvella Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PVLA
Palvella Therapeutics
2.9506 of 5 stars
$105.25
-3.1%
$199.53
+89.6%
+327.8%$1.51B$42.81MN/AN/A
LNTH
Lantheus
2.1715 of 5 stars
$99.86
+0.8%
$101.86
+2.0%
+23.8%$6.50B$1.54B24.041,193
PTGX
Protagonist Therapeutics
2.1525 of 5 stars
$100.07
-2.1%
$115.21
+15.1%
+79.1%$6.45B$46.02MN/A120
RYTM
Rhythm Pharmaceuticals
2.177 of 5 stars
$93.00
+1.7%
$131.81
+41.7%
+26.9%$6.37B$189.76MN/A140
SYRE
Spyre Therapeutics
2.4842 of 5 stars
$72.67
+0.2%
$90.25
+24.2%
+334.0%$6.29B$890KN/A73

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This page (NASDAQ:PVLA) was last updated on 6/8/2026 by MarketBeat.com Staff.
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