PowerUp Acquisition (PWUP) Competitors $0.31 +0.04 (+15.24%) As of 07/1/2025 Add Compare Share Share Competitors Stock AnalysisChartCompetitorsHeadlinesOwnershipSEC FilingsTrendsBuy This Stock PWUP vs. APRE, TLPH, JBIO, TSBX, GTBP, TRAW, ORGS, CLDI, NLSP, and BMRAShould you be buying PowerUp Acquisition stock or one of its competitors? The main competitors of PowerUp Acquisition include Aprea Therapeutics (APRE), Talphera (TLPH), Jade Biosciences (JBIO), Turnstone Biologics (TSBX), GT Biopharma (GTBP), Traws Pharma (TRAW), Orgenesis (ORGS), Calidi Biotherapeutics (CLDI), NLS Pharmaceutics (NLSP), and Biomerica (BMRA). These companies are all part of the "pharmaceutical products" industry. PowerUp Acquisition vs. Its Competitors Aprea Therapeutics Talphera Jade Biosciences Turnstone Biologics GT Biopharma Traws Pharma Orgenesis Calidi Biotherapeutics NLS Pharmaceutics Biomerica PowerUp Acquisition (NASDAQ:PWUP) and Aprea Therapeutics (NASDAQ:APRE) are both small-cap pharmaceutical products companies, but which is the superior investment? We will contrast the two businesses based on the strength of their institutional ownership, media sentiment, valuation, dividends, profitability, earnings, analyst recommendations and risk. Does the media favor PWUP or APRE? In the previous week, Aprea Therapeutics had 2 more articles in the media than PowerUp Acquisition. MarketBeat recorded 2 mentions for Aprea Therapeutics and 0 mentions for PowerUp Acquisition. PowerUp Acquisition's average media sentiment score of 0.00 beat Aprea Therapeutics' score of -0.05 indicating that PowerUp Acquisition is being referred to more favorably in the media. Company Overall Sentiment PowerUp Acquisition Neutral Aprea Therapeutics Neutral Do institutionals and insiders hold more shares of PWUP or APRE? 19.2% of PowerUp Acquisition shares are held by institutional investors. Comparatively, 34.2% of Aprea Therapeutics shares are held by institutional investors. 48.0% of PowerUp Acquisition shares are held by insiders. Comparatively, 13.6% of Aprea Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth. Do analysts recommend PWUP or APRE? Aprea Therapeutics has a consensus price target of $15.50, suggesting a potential upside of 785.71%. Given Aprea Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Aprea Therapeutics is more favorable than PowerUp Acquisition.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score PowerUp Acquisition 0 Sell rating(s) 0 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 0.00Aprea Therapeutics 0 Sell rating(s) 0 Hold rating(s) 2 Buy rating(s) 0 Strong Buy rating(s) 3.00 Which has stronger valuation and earnings, PWUP or APRE? PowerUp Acquisition has higher earnings, but lower revenue than Aprea Therapeutics. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioPowerUp AcquisitionN/AN/AN/AN/AN/AAprea Therapeutics$1.50M6.45-$12.96M-$2.37-0.74 Which has more volatility & risk, PWUP or APRE? PowerUp Acquisition has a beta of 0.05, meaning that its stock price is 95% less volatile than the S&P 500. Comparatively, Aprea Therapeutics has a beta of 1.19, meaning that its stock price is 19% more volatile than the S&P 500. Is PWUP or APRE more profitable? PowerUp Acquisition has a net margin of 0.00% compared to Aprea Therapeutics' net margin of -1,095.02%. PowerUp Acquisition's return on equity of 0.00% beat Aprea Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets PowerUp AcquisitionN/A N/A N/A Aprea Therapeutics -1,095.02%-68.39%-55.74% SummaryAprea Therapeutics beats PowerUp Acquisition on 7 of the 12 factors compared between the two stocks. Get PowerUp Acquisition News Delivered to You Automatically Sign up to receive the latest news and ratings for PWUP and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding PWUP and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart PWUP vs. The Competition Export to ExcelMetricPowerUp AcquisitionHolding Offices IndustryManufacturing SectorNASDAQ ExchangeMarket Cap$2.41M$177.53M$2.26B$9.02BDividend YieldN/A5.41%2.66%4.10%P/E RatioN/A2.4822.9520.30Price / SalesN/A435.6348.63104.24Price / CashN/A74.78N/A57.47Price / BookN/A6.47165.655.68Net IncomeN/A$3.67M-$211.97M$249.13M7 Day Performance1.31%0.07%1.57%3.30%1 Month Performance-19.27%2.60%3.32%5.20%1 Year PerformanceN/A75.56%24.34%21.37% PowerUp Acquisition Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)PWUPPowerUp AcquisitionN/A$0.31+15.2%N/A-97.2%$2.41MN/A0.00N/AGap UpHigh Trading VolumeAPREAprea Therapeutics2.8664 of 5 stars$1.63+1.6%$15.50+853.8%-54.8%$8.99M$1.50M-0.697TLPHTalphera2.0102 of 5 stars$0.43-2.2%$5.00+1,061.4%-49.5%$8.83M$650K-0.9619Positive NewsJBIOJade Biosciences2.7578 of 5 stars$10.48+6.2%$14.00+33.6%N/A$8.80MN/A-0.1820Positive NewsHigh Trading VolumeTSBXTurnstone Biologics1.6854 of 5 stars$0.38+3.1%$0.45+18.5%-83.9%$8.79M$19.31M-0.1482Gap DownGTBPGT Biopharma1.4551 of 5 stars$3.32+3.4%$11.00+231.3%+1.3%$8.60MN/A-0.588TRAWTraws Pharma0.2158 of 5 stars$1.53-1.3%N/AN/A$8.51M$230K-0.0517ORGSOrgenesis1.8891 of 5 stars$1.75+0.3%N/AN/A$8.40M$662K0.00150Gap DownCLDICalidi Biotherapeutics0.226 of 5 stars$0.26-8.7%$10.00+3,744.7%N/A$8.27M$50K0.0038High Trading VolumeNLSPNLS PharmaceuticsN/A$2.27-2.6%N/A+1,109.1%$8.17MN/A0.006BMRABiomerica0.5119 of 5 stars$3.16+4.3%N/A-7.9%$8.06M$5.41M-1.3660News CoverageNegative News Related Companies and Tools Related Companies APRE Competitors TLPH Competitors JBIO Competitors TSBX Competitors GTBP Competitors TRAW Competitors ORGS Competitors CLDI Competitors NLSP Competitors BMRA Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:PWUP) was last updated on 7/4/2025 by MarketBeat.com Staff From Our PartnersSpecial gold investment soars 2,300% ... 5,090% ... 9,850%In my 54 years as an investor, I’ve seen my share of gold bull markets. 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