Replimune Group (REPL) Stock Price, News & Analysis

Company Overview

Replimune Group, Inc., a clinical-stage biotechnology company, focuses on the development of oncolytic immunotherapies to treat cancer. The company's proprietary tumor-directed oncolytic immunotherapy product candidates are designed and intended to activate the immune system against cancer. Its lead product candidate is RP1, a selectively replicating version of HSV-1 that expresses GALV-GP R(-) and human GM-CSF, which is in Phase I/II clinical trials for a range of solid tumors; and that has completed Phase II clinical trials for treating cutaneous squamous cell carcinoma. The company is also developing RP2, which is in Phase I clinical trials to express an anti-CTLA-4 antibody-like protein to block the inhibition of the immune response otherwise caused by CTLA-4; and RP3 that is in Phase I clinical trial to express immune-activating proteins that stimulate T cells. Replimune Group, Inc. was founded in 2015 and is headquartered in Woburn, Massachusetts.

Key Stats

• Today's Range: $5.33 to $5.54
• 50-Day Range: $2.81 to $12.63
• 52-Week Range: $2.68 to $17.00
• Volume: 1.35 million shs
• Average Volume: 3.98 million shs
• Market Capitalization: $422.07 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $6.50
• Consensus Rating: Hold

Replimune Group Stock Analysis - MarketRank™

Replimune Group scored higher than 78% of companies evaluated by MarketBeat, and ranked 226th out of 944 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.1 / 5
• Analyst Rating: Hold

Consensus Rating

Replimune Group has received a consensus rating of Hold. The company's average rating score is 2.10, and is based on 2 buy ratings, 7 hold ratings, and 1 sell rating.

Amount of Analyst Coverage

Replimune Group has been the subject of 10 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Replimune Group are expected to grow in the coming year, from ($2.97) to ($2.55) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Replimune Group is -1.66, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Replimune Group is -1.66, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Replimune Group has a P/B Ratio of 1.25. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

28.80% of the float of Replimune Group has been sold short.

Short Interest Ratio / Days to Cover

Replimune Group has a short interest ratio ("days to cover") of 2.5, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Replimune Group has recently increased by 165.71%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Replimune Group does not currently pay a dividend.

Dividend Growth

Replimune Group does not have a long track record of dividend growth.

Sustainability and ESG

• Score: 4.5 / 5
• Environmental Score: -1.28

Percentage of Shares Shorted

28.80% of the float of Replimune Group has been sold short.

Short Interest Ratio / Days to Cover

Replimune Group has a short interest ratio ("days to cover") of 2.5, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Replimune Group has recently increased by 165.71%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 1.8 / 5
• News Sentiment: 0.27

News Sentiment

Replimune Group has a news sentiment score of 0.27. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 1.03 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 32 news articles for Replimune Group this week, compared to 8 articles on an average week.

Search Interest

Only 16 people have searched for REPL on MarketBeat in the last 30 days. This is a decrease of -61% compared to the previous 30 days.

MarketBeat Follows

Only 14 people have added Replimune Group to their MarketBeat watchlist in the last 30 days. This is a decrease of -56% compared to the previous 30 days.

Company Ownership

• Score: 2.5 / 5
• Insider Trading: Selling Shares

Insider Buying vs. Insider Selling

In the past three months, Replimune Group insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $49,157.00 in company stock.

Percentage Held by Insiders

Only 5.20% of the stock of Replimune Group is held by insiders.

Percentage Held by Institutions

92.53% of the stock of Replimune Group is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

REPL Stock Analysis - Frequently Asked Questions

How have REPL shares performed this year?

Replimune Group's stock was trading at $12.11 at the beginning of 2025. Since then, REPL stock has decreased by 55.4% and is now trading at $5.4070.

How were Replimune Group's earnings last quarter?

Replimune Group, Inc. (NASDAQ:REPL) issued its earnings results on Thursday, August, 7th. The company reported ($0.95) earnings per share for the quarter, missing the consensus estimate of ($0.83) by $0.12.

When did Replimune Group IPO?

Replimune Group (REPL) raised $100 million in an IPO on Friday, July 20th 2018. The company issued 6,700,000 shares at a price of $14.00-$16.00 per share. J.P. Morgan, Leerink Partners and BMO Capital Markets acted as the underwriters for the IPO.

Who are Replimune Group's major shareholders?

Top institutional shareholders of Replimune Group include Redmile Group LLC (5.98%), Marshall Wace LLP (2.39%), Geode Capital Management LLC (2.09%) and Sofinnova Investments Inc.. Insiders that own company stock include Robert Coffin, Philip Astley-Sparke, Colin Love, Sushil Patel, Pamela Esposito, Konstantinos Xynos, Tanya Lewis, Emily Luisa Hill, Christopher Sarchi and Andrew Schwendenman.
View institutional ownership trends.

How do I buy shares of Replimune Group?

Shares of REPL stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Replimune Group own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Replimune Group investors own include Tesla (TSLA), Meta Platforms (META), NVIDIA (NVDA), Advanced Micro Devices (AMD), JPMorgan Chase & Co. (JPM), Visa (V) and Home Depot (HD).

Company Calendar

• Last Earnings: 8/07/2025
• Today: 8/29/2025
• Next Earnings (Estimated): 11/11/2025
• Fiscal Year End: 3/31/2026

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:REPL
• CIK: 1737953
• Web: www.replimune.com
• Phone: (781) 222-9600
• Fax: N/A
• Employees: 210
• Year Founded: 2015

Price Target and Rating

• Average Price Target for Replimune Group: $6.50
• High Price Target: $22.00
• Low Price Target: $2.00
• Potential Upside/Downside: +20.8%
• Consensus Rating: Hold
• Rating Score (0-4): 2.10
• Research Coverage: 10 Analysts

Profitability

• EPS (Trailing Twelve Months): ($3.24)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$247.30 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -69.34%
• Return on Assets: -52.81%

Debt

• Debt-to-Equity Ratio: 0.21
• Current Ratio: 6.94
• Quick Ratio: 6.94

Sales & Book Value

• Annual Sales: N/A
• Price / Sales: N/A
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $4.31 per share
• Price / Book: 1.25

Miscellaneous

• Outstanding Shares: 78,060,000
• Free Float: 73,997,000
• Market Cap: $419.96 million
• Optionable: Optionable
• Beta: 0.67