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Regulus Therapeutics (RGLS) Short Interest Ratio & Short Volume

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Regulus Therapeutics Short Interest Overview

As of June 15, 2025, Regulus Therapeutics (RGLS) had a short interest of 1.76 million shares sold short, representing 3.07% of the public float. This marks a -15.79% decrease in short interest since the prior report. The short interest ratio (days to cover) is 0.7, meaning it would take 0.7 days of the average trading volume of 2.68 million shares to cover all short positions.

Current Short Interest
1,760,000 shares
Previous Short Interest
2,090,000 shares
Change Vs. Previous Month
-15.79%
Dollar Volume Sold Short
$14.27 million
Short Interest Ratio
0.7 Days to Cover
Last Record Date
June 15, 2025
Outstanding Shares
69,230,000 shares
Float Size
57,330,000 shares
Short Percent of Float
3.07%
Today's Trading Volume
0 shares
Average Trading Volume
2,684,017 shares
Today's Volume Vs. Average
0%
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Short Interest ChartDays to Cover ChartShort Percent of Float Chart

RGLS Short Interest Over Time

RGLS Days to Cover Over Time

RGLS Percentage of Float Shorted Over Time

Regulus Therapeutics Tesla Short Interest History & Recent Changes

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Report DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date
6/15/20251,760,000 shares $14.27 million -15.8%3.1%0.7 $8.11
5/31/20252,090,000 shares $16.57 million +9.4%3.7%1 $7.93
5/15/20251,910,000 shares $14.99 million -29.5%3.3%1 $7.85
4/30/20252,710,000 shares $21.63 million +28.4%4.9%1.5 $7.98
4/15/20252,110,000 shares $4.11 million -20.7%4.0%1.7 $1.95
3/31/20252,660,000 shares $4.66 million +30.4%5.0%2.4 $1.75
3/15/20252,040,000 shares $3.02 million -8.9%3.8%4.4 $1.48
2/28/20252,240,000 shares $3.02 million +10.3%4.3%5.1 $1.35
2/15/20252,030,000 shares $2.46 million +3.6%3.9%4.5 $1.21
1/31/20251,960,000 shares $1.96 million +11.4%3.7%4.1 $1.00
1/15/20251,760,000 shares $2.24 million +3.5%3.3%5 $1.27
12/31/20241,700,000 shares $2.69 million +4.9%3.2%5.1 $1.58
12/15/20241,620,000 shares $2.56 million +15.7%3.1%4.9 $1.58
11/30/20241,400,000 shares $2.25 million -14.6%2.7%4 $1.61
11/15/20241,640,000 shares $2.35 million -3.0%3.1%4.6 $1.43
10/31/20241,690,000 shares $2.47 million -32.4%3.2%4.7 $1.46
10/15/20242,500,000 shares $3.75 million -12.3%4.7%7.3 $1.50
9/30/20242,850,000 shares $4.47 million -13.4%5.4%7.7 $1.57
9/15/20243,290,000 shares $5.30 million -1.2%6.2%4.6 $1.61
8/31/20243,330,000 shares $5.59 million -7.0%6.3%4.2 $1.68
8/15/20243,580,000 shares $5.69 million -8.7%6.8%4.4 $1.59
7/31/20243,920,000 shares $7.06 million -9.7%7.4%4.6 $1.80
7/15/20244,340,000 shares $7.55 million -18.1%8.2%5.3 $1.74
6/30/20245,300,000 shares $9.46 million +48.0%10.0%6.6 $1.79
6/15/20243,580,000 shares $8.63 million +38.2%6.8%5.1 $2.41
5/31/20242,590,000 shares $5.93 million -10.1%4.9%0.8 $2.29
5/15/20242,880,000 shares $5.82 million -31.6%5.4%0.9 $2.02
4/30/20244,210,000 shares $9.68 million -32.9%7.3%1.4 $2.30
4/15/20246,270,000 shares $17.43 million +15.7%10.9%2.1 $2.78
3/31/20245,420,000 shares $15.61 million +5.7%9.4%1.8 $2.88
3/15/20245,130,000 shares $10.82 million +9,244.3%13.0%1.8 $2.11
2/29/202454,900 shares $80.70 thousand -43.4%0.3%1.4 $1.47
2/15/202497,000 shares $143.56 thousand -16.6%0.6%2.6 $1.48
1/31/2024116,300 shares $147.70 thousand -7.3%0.7%4.4 $1.27
1/15/2024125,500 shares $163.15 thousand -9.3%0.7%5.1 $1.30
12/31/2023138,400 shares $177.15 thousand -6.6%0.8%6.9 $1.28
12/15/2023148,100 shares $202.90 thousand -0.1%0.9%7.6 $1.37
11/30/2023148,200 shares $194.14 thousand -18.3%0.9%4.4 $1.31
11/15/2023181,300 shares $252.01 thousand -5.2%1.0%4.9 $1.39
10/31/2023191,200 shares $231.35 thousand -0.7%1.1%5.4 $1.21
10/15/2023192,600 shares $242.68 thousand -1.0%1.2%5.5 $1.26
9/30/2023194,500 shares $266.47 thousand -0.2%1.2%5.6 $1.37
9/15/2023194,800 shares $331.16 thousand +4.2%1.2%5.6 $1.70
8/31/2023187,000 shares $291.72 thousand -10.2%1.1%5.7 $1.56
8/15/2023208,300 shares $281.21 thousand -3.7%1.3%9.6 $1.35
7/31/2023216,300 shares $302.82 thousand -3.9%1.3%7.8 $1.40
7/15/2023225,000 shares $328.50 thousand -2.5%1.4%7.7 $1.46
6/30/2023230,700 shares $339.13 thousand +6.5%1.4%4.1 $1.47
6/15/2023216,700 shares $312.05 thousand +3.0%1.3%3.4 $1.44
5/31/2023210,300 shares $273.39 thousand -17.1%1.3%3.1 $1.30
5/15/2023253,700 shares $393.24 thousand +26.0%1.6%3.8 $1.55
4/30/2023201,300 shares $268.74 thousand +18.1%1.4%3.4 $1.34
4/15/2023170,500 shares $202.90 thousand -13.9%1.2%2.6 $1.19
3/31/2023198,000 shares $167.81 thousand +11.1%1.3%4.8 $0.85
3/15/2023178,200 shares $215.62 thousand -3.7%1.2%4 $1.21
2/28/2023185,100 shares $248.03 thousand -1.9%1.3%4.1 $1.34
2/15/2023188,600 shares $262.15 thousand -6.8%1.3%4.2 $1.39
1/31/2023202,400 shares $291.46 thousand -3.2%1.4%4.3 $1.44
1/15/2023209,000 shares $311.41 thousand +0.8%1.4%4.7 $1.49
12/30/2022207,400 shares $284.14 thousand -10.8%1.4%4.7 $1.37
12/15/2022232,600 shares $327.97 thousand -16.2%1.6%5.4 $1.41
11/30/2022277,500 shares $474.53 thousand -2.6%1.9%0.3 $1.71
11/15/2022284,900 shares $490.03 thousand +5.1%2.0%0.3 $1.72
10/31/2022271,100 shares $420.21 thousand -1.7%N/A0.3 $1.55
10/15/2022275,900 shares $449.72 thousand -7.4%N/A0.3 $1.63
9/30/2022297,900 shares $506.43 thousand -49.9%N/A0.3 $1.70
9/15/2022594,600 shares $1.24 million +98.7%N/A0.7 $2.09
8/31/2022299,300 shares $425.01 thousand -15.2%N/A0.4 $1.42
8/15/2022353,000 shares $638.93 thousand +56.1%N/A3 $1.81
7/31/2022226,200 shares $364.18 thousand -7.1%N/A1 $1.61
7/15/2022243,500 shares $560.05 thousand +1.4%N/A1.2 $2.30
6/30/2022240,100 shares $497.01 thousand -91.3%N/A1.2 $2.07
6/15/20222,770,000 shares $678.93 thousand -9.2%N/A1.4 $0.25
5/31/20223,050,000 shares $873.83 thousand -30.8%N/A1.5 $0.29
5/15/20224,410,000 shares $948.15 thousand +53.1%N/A2 $0.22
4/30/20222,880,000 shares $581.76 thousand -10.8%N/A2.7 $0.20
4/15/20223,230,000 shares $823.65 thousand -2.4%N/A2.8 $0.26
3/31/20223,310,000 shares $986.38 thousand +1.5%N/A2.3 $0.30
3/15/20223,260,000 shares $867.16 thousand +21.2%N/A2.3 $0.27
2/28/20222,690,000 shares $605.25 thousand -17.5%N/A1.9 $0.23
2/15/20223,260,000 shares $815.33 thousand +4.5%N/A2.5 $0.25
1/31/20223,120,000 shares $769.70 thousand +24.8%4.2%2.2 $0.25
1/15/20222,500,000 shares $617.50 thousand -8.8%3.3%1.5 $0.25
12/31/20212,740,000 shares $863.10 thousand -18.7%4.1%1.3 $0.32
12/15/20213,370,000 shares $1.18 million -0.6%5.1%1.6 $0.35
11/30/20213,390,000 shares $1.31 million -19.7%4.5%1.7 $0.39
11/15/20214,220,000 shares $1.76 million -4.5%N/A2.1 $0.42
10/29/20214,420,000 shares $2.04 million -8.3%N/A2.3 $0.46
10/15/20214,820,000 shares $2.34 million -8.5%N/A2.9 $0.49
9/30/20215,270,000 shares $3.64 million +6.0%N/A6.5 $0.69
9/15/20214,970,000 shares $3.48 million +0.4%N/A4 $0.70
8/31/20214,950,000 shares $3.84 million -5.9%N/A1.7 $0.78
8/13/20215,260,000 shares $3.53 million -0.8%N/A1.7 $0.67
7/30/20215,300,000 shares $3.71 million -12.3%8.2%1.7 $0.70
7/15/20216,040,000 shares $4.35 million -2.6%9.3%1.9 $0.72
6/30/20216,200,000 shares $5.04 million +4.7%9.6%1.9 $0.81
6/15/20215,920,000 shares $5.52 million +0.2%9.1%2 $0.93
5/28/20215,910,000 shares $5.83 million No Change9.1%1.6 $0.99
5/14/20215,910,000 shares $4.85 million -5.4%N/A2.1 $0.82

RGLS Short Interest - Frequently Asked Questions

Short interest is the volume of Regulus Therapeutics shares that have been sold short but have not yet been covered or closed out. As of June 15th, traders have sold 1,760,000 shares of RGLS short. 3.07% of Regulus Therapeutics' shares are currently sold short. Learn More on Regulus Therapeutics' current short interest.

The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. RGLS shares currently have a short interest ratio of 0.7. Learn More on Regulus Therapeutics's short interest ratio.

Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 3.07% of Regulus Therapeutics' floating shares are currently sold short.

Regulus Therapeutics saw a decrease in short interest in the month of June. As of June 15th, there was short interest totaling 1,760,000 shares, a decrease of 15.8% from the previous total of 2,090,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment.

Regulus Therapeutics currently has issued a total of 69,230,000 shares. Some of Regulus Therapeutics' outstanding shares are available for trading, while others are subject to various restrictions. The public float, also referred to as floating shares or "the float", are shares that publicly owned, unrestricted and available to trade on the open market. Regulus Therapeutics currently has a public float of 57,330,000 shares.

3.07% of Regulus Therapeutics' shares are currently sold short. Here is how the short interest of companies in the industry of "biotechnology" compare to Regulus Therapeutics: Celldex Therapeutics, Inc. (13.06%), Innoviva, Inc. (9.27%), Novavax, Inc. (28.73%), Zenas BioPharma, Inc. (22.85%), Geron Corporation (13.04%), OPKO Health, Inc. (8.64%), MannKind Corporation (9.83%), Lexicon Pharmaceuticals, Inc. (6.50%), Ironwood Pharmaceuticals, Inc. (12.78%), Rigel Pharmaceuticals, Inc. (24.91%),

As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($69.26 billion), Invesco QQQ ($25.22 billion), iShares Russell 2000 ETF ($20.33 billion), iShares 20+ Year Treasury Bond ETF ($9.99 billion), Strategy Inc ($9.12 billion), Canadian Natural Resources Limited ($6.73 billion), SPDR S&P Biotech ETF ($6.52 billion), Invesco S&P 500 Equal Weight ETF ($5.60 billion), Financial Select Sector SPDR Fund ($4.64 billion), and iShares iBoxx $ Investment Grade Corporate Bond ETF ($4.59 billion). View all of the most shorted stocks.

Short selling RGLS is an investing strategy that aims to generate trading profit from Regulus Therapeutics as its price is falling. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit.

A short squeeze for Regulus Therapeutics occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of RGLS, which in turn drives the price of the stock up even further.

Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including RGLS, twice per month. The most recent reporting period available is June, 15 2025.

Understanding short interest metrics can help you assess how traders are positioning around a stock like RGLS:

  • Shares Sold Short: The total number of shares that have been sold by short sellers but have not yet been covered or closed out. A high number may indicate bearish sentiment.
  • Short Float: The percentage of a company’s publicly available shares (or "float") that are sold short. A higher short float suggests a greater portion of the stock is being bet against.
  • Days to Cover (Short Interest Ratio): This estimates how many days it would take short sellers to cover their positions, based on average daily trading volume. Higher values can signal potential for a short squeeze if buying pressure increases.

These metrics are often used by traders to gauge sentiment, volatility risk, and the potential for price movements based on short covering activity.


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This page (NASDAQ:RGLS) was last updated on 5/9/2026 by MarketBeat.com Staff.
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