Septerna (SEPN) News Today $23.14 +0.65 (+2.89%) Closing price 10/9/2025 04:00 PM EasternExtended Trading$23.35 +0.21 (+0.91%) As of 10/9/2025 06:58 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Headlines Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock SEPN Latest News All Sources Trusted Sources MarketBeat Barchart Benzinga Bloomberg GlobeNewswire GuruFocus MarketWatch Motley Fool NASDAQ PR Newswire Reuters Seeking Alpha TalkMarkets The Street TipRanks The Wall Street Journal Wall Street Zen Yahoo Finance Source Sentiment refers to the positivity or negativity of each headline according to our language processing algorithm. Sentiment All Sentiments Very Positive Positive Neutral Negative Very Negative Most Recent October 2025 September 2025 August 2025 July 2025 June 2025 May 2025 April 2025 March 2025 February 2025 January 2025 December 2024 November 2024 October 2024 September 2024 August 2024 July 2024 June 2024 May 2024 April 2024 March 2024 February 2024 January 2024 December 2023 November 2023 October 2023 September 2023 August 2023 July 2023 June 2023 May 2023 April 2023 March 2023 February 2023 January 2023 December 2022 November 2022 Time Period Weiss Ratings Reaffirms "Sell (D-)" Rating for Septerna (NASDAQ:SEPN)October 9 at 4:47 AM | marketbeat.comSepterna (NASDAQ:SEPN) Shares Up 8.5% - Should You Buy?October 8 at 2:42 PM | marketbeat.comSepterna, Inc. (NASDAQ:SEPN) Given Consensus Rating of "Moderate Buy" by BrokeragesOctober 5, 2025 | marketbeat.comSepterna Up 12%, Insider Buyers Are Up 219%October 2, 2025 | finance.yahoo.comSepterna, Inc. Expands Board with New R&D ChairSeptember 29, 2025 | tipranks.comSepterna Appoints Veteran Biotechnology Leader Keith Gottesdiener, M.D., to its Board of DirectorsSeptember 29, 2025 | globenewswire.comSepterna (NASDAQ:SEPN) Stock Rating Upgraded by Wall Street ZenSeptember 21, 2025 | marketbeat.comSepterna (NASDAQ:SEPN) Shares Up 9.2% - Here's WhySeptember 19, 2025 | marketbeat.comSepterna (NASDAQ:SEPN) Downgraded to "Sell" Rating by Wall Street ZenSeptember 15, 2025 | marketbeat.comSepterna (NASDAQ:SEPN) Stock Price Down 3.9% - What's Next?September 13, 2025 | marketbeat.comSepterna, Inc. (NASDAQ:SEPN) Given Consensus Recommendation of "Moderate Buy" by AnalystsSeptember 12, 2025 | marketbeat.comCantor Fitzgerald Sticks to Its Buy Rating for Septerna, Inc. (SEPN)September 11, 2025 | theglobeandmail.com23,961 Shares in Septerna, Inc. $SEPN Acquired by Nuveen LLCSeptember 8, 2025 | marketbeat.comSepterna (NASDAQ:SEPN) Upgraded to Hold at Wall Street ZenSeptember 8, 2025 | marketbeat.comCheckpoint Capital L.P. Acquires New Position in Septerna, Inc. $SEPNSeptember 6, 2025 | marketbeat.comSepterna (NASDAQ:SEPN) Stock Price Up 8.9% - Time to Buy?September 5, 2025 | marketbeat.comBVF Inc. IL Has $25.45 Million Stock Position in Septerna, Inc. $SEPNSeptember 5, 2025 | marketbeat.com720,848 Shares in Septerna, Inc. $SEPN Acquired by ADAR1 Capital Management LLCSeptember 4, 2025 | marketbeat.comSepterna, Inc. $SEPN Shares Sold by Charles Schwab Investment Management Inc.September 4, 2025 | marketbeat.comSepterna Updates Presentation on Drug Discovery ProgressSeptember 3, 2025 | msn.comDriehaus Capital Management LLC Has $18.08 Million Stock Position in Septerna, Inc. $SEPNSeptember 1, 2025 | marketbeat.comSwiss National Bank Purchases Shares of 30,100 Septerna, Inc. $SEPNAugust 30, 2025 | marketbeat.comSepterna to Participate in Upcoming Investor ConferencesAugust 27, 2025 | globenewswire.comStonepine Capital Management LLC Invests $394,000 in Septerna, Inc. $SEPNAugust 26, 2025 | marketbeat.comSepterna Announces Dosing of the First Participants in Phase 1 Clinical ...August 23, 2025 | seekingalpha.comSepterna doses first participants in Phase 1 trial of SEP-631August 22, 2025 | msn.comResearch Analysts Set Expectations for Septerna Q3 EarningsAugust 22, 2025 | marketbeat.comSepterna, Inc.: Advancements in Clinical Trials and Strategic Focus Drive Buy RatingAugust 21, 2025 | tipranks.comSepterna Begins Phase 1 Trial for SEP-631August 21, 2025 | tipranks.comSepterna Announces Dosing of the First Participants in Phase 1 Clinical Trial of SEP-631, an Oral Small Molecule MRGPRX2 Negative Allosteric Modulator for the Treatment of Mast Cell-Driven DiseasesAugust 21, 2025 | globenewswire.comFY2025 EPS Estimates for Septerna Lowered by HC WainwrightAugust 21, 2025 | marketbeat.comSepterna, Inc. (NASDAQ:SEPN) Receives Average Rating of "Moderate Buy" from BrokeragesAugust 17, 2025 | marketbeat.comSepterna (NASDAQ:SEPN) Downgraded by Wall Street Zen to SellAugust 17, 2025 | marketbeat.comSepterna FY2025 EPS Forecast Lowered by Cantor FitzgeraldAugust 16, 2025 | marketbeat.comSepterna (SEPN) Projected to Post Earnings on ThursdayAugust 15, 2025 | marketbeat.comXTX Topco Ltd Invests $216,000 in Septerna, Inc. (NASDAQ:SEPN)August 14, 2025 | marketbeat.comSepterna (NASDAQ:SEPN) Shares Gap Down Following Weak EarningsAugust 13, 2025 | marketbeat.comSepterna Reports Q2 2025 Financial Results and ProgressAugust 13, 2025 | tipranks.comSepterna (NASDAQ:SEPN) Releases Earnings ResultsAugust 12, 2025 | marketbeat.comSepterna, Inc.: Septerna Highlights Business Progress and Reports Second Quarter 2025 Financial ResultsAugust 12, 2025 | finanznachrichten.deSepterna shares drop as quarterly loss widens despite better-than-expected EPSAugust 12, 2025 | in.investing.comSepterna Highlights Business Progress and Reports Second Quarter 2025 Financial ResultsAugust 11, 2025 | globenewswire.comTrv Gp Vi LLC Has $24.39 Million Position in Septerna, Inc. (NASDAQ:SEPN)August 8, 2025 | marketbeat.comSepterna Appoints Liz Bhatt as New PresidentAugust 4, 2025 | tipranks.comSepterna (NASDAQ:SEPN) Trading Down 6.6% - Here's WhyJuly 30, 2025 | marketbeat.comSepterna (NASDAQ:SEPN) Trading 2.4% Higher - Here's WhyJuly 26, 2025 | marketbeat.comSepterna, Inc. (SEPN)July 11, 2025 | finance.yahoo.comSepterna Inc. Company & People | SEPN - Barron'sJuly 10, 2025 | barrons.comSepterna Inc.July 9, 2025 | barrons.comQ2 Earnings Forecast for Septerna Issued By HC WainwrightJune 25, 2025 | marketbeat.com Get Septerna News Delivered to You Automatically Sign up to receive the latest news and ratings for SEPN and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. SEPN Media Mentions By Week SEPN Media Sentiment Learn about the media sentiment score. Each headline receives a score ranging from 2 (good news) to -2 (bad news). Our company news sentiment scores track the average news sentiment of articles about each company over the most recent 7 days in order to identify companies that are receiving positive press. SEPN News Sentiment▼0.800.77▲Average Medical News Sentiment SEPN News Coverage Learn about the media coverage comparison. We track news headlines from hundreds of news outlets and tag them by company. This chart compares the number of articles about this company in the last seven days compared with the average number of articles about this company on a typical week. SEPN Articles This Week▼54▲SEPN Articles Average Week Get the Latest News and Ratings for SEPN and Related Stocks Enter your email address to receive the latest news and analysts' ratings for Septerna and its competitors. Sign Up View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. 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