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Septerna (SEPN) Institutional Ownership

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$30.55 +0.61 (+2.04%)
Closing price 04:00 PM Eastern
Extended Trading
$30.57 +0.02 (+0.07%)
As of 04:10 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Septerna (NASDAQ:SEPN)

Number of
Institutional Buyers
(last 12 months)
68
Total
Institutional Inflows
(last 12 months)
$163.35M
Number of
Institutional Sellers
(last 12 months)
21
Total
Institutional Outflows
(last 12 months)
$102.25M
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Skip Chart & View Institutional Buying and Selling Data

SEPN Institutional Buying and Selling by Quarter

Septerna Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
5/19/2026 Bank of America Corp DE25,973$624K0.0%-30.9%0.058%
5/19/2026 Janus Henderson Group PLC890,754$21.33M0.0%N/A1.976%
5/18/2026 ADAR1 Capital Management LLC1,089,818$26.19M1.5%-5.9%2.418%
5/16/2026 First Light Asset Management LLC732,860$17.61M1.6%+18.0%1.626%
5/15/2026 Rangeley Capital LLC39,800$956K0.9%-39.5%0.088%
5/14/2026 Renaissance Technologies LLC37,700$906K0.0%N/A0.084%
5/14/2026 Public Employees Retirement System of Ohio3,374$81K0.0%-68.2%0.007%
5/7/2026 Swiss National Bank22,100$531K0.0%N/A0.049%
5/5/2026 Bank of New York Mellon Corp58,709$1.41M0.0%+6.1%0.131%
4/27/2026 Y Intercept Hong Kong Ltd25,770$619K0.0%N/A0.057%
4/25/2026 Strs Ohio17,200$413K0.0%+17.8%0.038%
3/3/2026 Caitong International Asset Management Co. Ltd3,170$88K0.0%N/A0.007%
2/26/2026 Seven Fleet Capital Management LP11,445$319K0.2%N/A0.026%
2/19/2026 Invesco Ltd.162,014$4.52M0.0%-8.5%0.362%
2/18/2026 XTX Topco Ltd23,315$650K0.0%N/A0.052%
2/18/2026 VARCOV Co.22,634$631K0.2%N/A0.051%
2/18/2026 Virtus Investment Advisers LLC10,457$292K0.1%N/A0.023%
2/18/2026 Tudor Investment Corp ET AL18,053$503K0.0%N/A0.040%
2/18/2026 Numerai GP LLC45,866$1.28M0.2%N/A0.102%
2/18/2026 Perceptive Advisors LLC433,160$12.08M0.2%-20.0%0.968%
2/18/2026 Millennium Management LLC107,463$3.00M0.0%-72.0%0.240%
2/18/2026 Balyasny Asset Management L.P.3,571$100K0.0%N/A0.008%
2/18/2026 BVF Inc. IL1,720,782$47.98M1.6%-57.1%3.844%
2/17/2026 Logos Global Management LP23,548$657K0.0%-71.8%0.053%
2/17/2026 ADAR1 Capital Management LLC1,157,611$32.27M2.4%-1.6%2.586%
2/17/2026 AQR Capital Management LLC7,826$218K0.0%N/A0.017%
2/17/2026 First Light Asset Management LLC620,811$17.31M1.3%N/A1.387%
2/17/2026 Trexquant Investment LP44,005$1.23M0.0%N/A0.098%
2/17/2026 Jump Financial LLC8,399$234K0.0%N/A0.019%
2/17/2026 Price T Rowe Associates Inc. MD25,443$710K0.0%-7.2%0.057%
2/17/2026 Public Employees Retirement System of Ohio10,594$295K0.0%N/A0.024%
2/17/2026 Russell Investments Group Ltd.15,310$427K0.0%+707.5%0.034%
2/17/2026 Atom Investors LP9,791$273K0.0%N/A0.022%
2/17/2026 ExodusPoint Capital Management LP37,867$1.06M0.0%N/A0.085%
2/17/2026 Graham Capital Management L.P.8,971$250K0.0%N/A0.020%
2/16/2026 Squarepoint Ops LLC14,847$414K0.0%N/A0.033%
2/16/2026 Barclays PLC38,147$1.06M0.0%+26.7%0.085%
2/13/2026 Marshall Wace LLP226,901$6.33M0.0%N/A0.507%
2/13/2026 Kalehua Capital Management LLC194,544$5.42M5.0%N/A0.435%
2/13/2026 Bank of Nova Scotia8,300$231K0.0%N/A0.019%
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2/13/2026 Jacobs Levy Equity Management Inc.61,370$1.71M0.0%+71.5%0.137%
2/13/2026 Siren L.L.C.2,000,000$55.76M1.7%-9.2%4.467%
2/13/2026 State Street Corp540,028$15.06M0.0%+28.9%1.206%
2/13/2026 Dynamic Technology Lab Private Ltd10,810$301K0.1%N/A0.024%
2/13/2026 Caitong International Asset Management Co. Ltd1,901$53K0.1%N/A0.004%
2/13/2026 Wells Fargo & Company MN26,529$740K0.0%+31.7%0.059%
2/12/2026 Federated Hermes Inc.78,905$2.20M0.0%N/A0.176%
2/12/2026 New York State Common Retirement Fund5,600$156K0.0%+93.1%0.013%
2/12/2026 Nuveen LLC25,798$719K0.0%+7.7%0.058%
2/12/2026 Group One Trading LLC944$26K0.0%-111.8%0.002%
2/11/2026 Primecap Management Co. CA546,100$15.23M0.0%N/A1.220%
2/11/2026 Deutsche Bank AG14,879$415K0.0%+5.3%0.033%
2/11/2026 Franklin Resources Inc.16,852$470K0.0%N/A0.038%
2/11/2026 Los Angeles Capital Management LLC18,550$517K0.0%N/A0.041%
2/10/2026 Goldman Sachs Group Inc.2,715,129$75.70M0.0%+86.6%6.065%
2/10/2026 Intech Investment Management LLC13,283$370K0.0%N/A0.030%
2/9/2026 Geode Capital Management LLC572,734$15.97M0.0%+5.0%1.279%
2/6/2026Global Retirement Partners LLC1,256$35K0.0%N/A0.003%
2/6/2026 Covestor Ltd1,941$54K0.0%-46.4%0.004%
2/5/2026 Baader Bank Aktiengesellschaft10,000$279K0.0%N/A0.022%
2/2/2026 Strs Ohio14,600$407K0.0%N/A0.033%
1/29/2026 China Universal Asset Management Co. Ltd.10,296$287K0.0%N/A0.023%
1/26/2026 Mirae Asset Global Investments Co. Ltd.2,176$61K0.0%N/A0.005%
1/1/2026 JPMorgan Chase & Co.8,736$164K0.0%-13.5%0.020%
11/17/2025 Jacobs Levy Equity Management Inc.35,778$673K0.0%N/A0.080%
11/17/2025 PharVision Advisers LLC11,932$224K0.1%+17.5%0.027%
11/17/2025 VR Adviser LLC610,808$11.49M0.6%+13.0%1.364%
11/17/2025 Verition Fund Management LLC20,131$379K0.0%N/A0.045%
11/17/2025 Quarry LP1,736$33K0.0%-51.8%0.004%
11/17/2025 Millennium Management LLC384,200$7.23M0.0%+639.6%0.858%
11/17/2025 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.9,791$184K0.0%-16.3%0.022%
11/17/2025 Checkpoint Capital L.P.283,158$5.33M1.8%-51.7%0.632%
11/17/2025 Bank of America Corp DE51,495$969K0.0%-48.1%0.115%
11/14/2025 ADAR1 Capital Management LLC1,176,491$22.13M2.1%+38.9%2.628%
11/14/2025 Longaeva Partners L.P.57,064$1.07M0.2%N/A0.127%
11/14/2025 Two Sigma Investments LP92,334$1.74M0.0%+18.9%0.206%
11/14/2025 Avoro Capital Advisors LLC1,337,500$25.16M0.3%+8.1%2.987%
11/13/2025 Invesco Ltd.177,070$3.33M0.0%+1,396.4%0.397%
11/13/2025 UBS Group AG59,046$1.11M0.0%-18.4%0.132%
11/13/2025 BNP Paribas Financial Markets4,155$78K0.0%+88.0%0.009%
11/13/2025 Russell Investments Group Ltd.1,896$36K0.0%N/A0.004%
11/7/2025Vanguard Group Inc.1,518,757$28.57M0.0%+7.4%3.406%
11/7/2025 JPMorgan Chase & Co.8,736$164K0.0%-13.5%0.020%
11/6/2025 Rhumbline Advisers27,604$519K0.0%-3.4%0.062%
10/30/2025 Covestor Ltd3,620$68K0.0%+55.8%0.008%
8/15/2025 Soleus Capital Management L.P.75,456$798K0.1%-90.0%0.169%
8/15/2025 Rangeley Capital LLC58,605$619K0.8%+10.7%0.131%
8/15/2025 Perceptive Advisors LLC541,450$5.72M0.5%N/A1.215%
8/15/2025 Boothbay Fund Management LLC24,142$255K0.0%N/A0.054%
8/15/2025 Bank of America Corp DE99,213$1.05M0.0%+758.3%0.223%
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8/14/2025 VR Adviser LLC540,453$5.71M0.4%N/A1.213%
8/13/2025CW Advisors LLC12,589$133K0.0%N/A0.028%
8/13/2025 PharVision Advisers LLC10,152$107K0.2%N/A0.023%
8/13/2025 Sio Capital Management LLC584,435$6.18M2.4%-25.9%1.312%
8/13/2025 Quadrature Capital Ltd10,125$107K0.0%N/A0.023%
8/12/2025 XTX Topco Ltd22,330$236K0.0%-40.2%0.050%
8/12/2025 Rhumbline Advisers28,572$302K0.0%+22.5%0.064%
8/12/2025 JPMorgan Chase & Co.10,101$107K0.0%+15.0%0.023%
8/11/2025 Universal Beteiligungs und Servicegesellschaft mbH222,702$2.35M0.0%+116.7%0.500%
8/8/2025 Intech Investment Management LLC12,200$129K0.0%N/A0.027%


SEPN Institutional Ownership - Frequently Asked Questions

During the previous two years, 112 institutional investors and hedge funds held shares of Septerna. The most heavily invested institutionals were RA Capital Management L.P. ($160.21M), TRV GP V LLC ($142.34M), Goldman Sachs Group Inc. ($75.70M), Samsara BioCapital LLC ($63.40M), Siren L.L.C. ($55.76M), BVF Inc. IL ($47.98M), and Deep Track Capital LP ($43.81M).Learn more on Septerna's institutional investors.

Of the 107 institutional investors that purchased Septerna's stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: RA Capital Management L.P. ($7.00M), TRV GP V LLC ($6.22M), BVF Inc. IL ($4.40M), TRV GP VI LLC ($4.21M), Driehaus Capital Management LLC ($3.12M), Samsara BioCapital LLC ($2.77M), and Janus Henderson Group PLC ($1.99M).

Institutional investors have bought a total of 7,311,971 shares in the last 24 months. This purchase volume represents approximately $163.35M in transactions.

Of the 21 institutional investors that sold Septerna's stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: BVF Inc. IL ($2.30M), Soleus Capital Management L.P. ($675.90K), Checkpoint Capital L.P. ($303.32K), Millennium Management LLC ($276.74K), Sio Capital Management LLC ($204.24K), Siren L.L.C. ($202.51K), and Perceptive Advisors LLC ($108.29K).

Institutional investors have sold a total of 4,359,722 shares in the last 24 months. This volume of shares sold represents approximately $102.25M in transactions.


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This page (NASDAQ:SEPN) was last updated on 6/3/2026 by MarketBeat.com Staff.
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