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Septerna (SEPN) Institutional Ownership

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$28.32 +3.57 (+14.42%)
Closing price 04:00 PM Eastern
Extended Trading
$28.80 +0.48 (+1.71%)
As of 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Septerna (NASDAQ:SEPN)

Number of
Institutional Buyers
(last 12 months)
72
Total
Institutional Inflows
(last 12 months)
$163.29M
Number of
Institutional Sellers
(last 12 months)
21
Total
Institutional Outflows
(last 12 months)
$101.02M
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SEPN Institutional Buying and Selling by Quarter

Septerna Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
5/14/2026Public Employees Retirement System of Ohio3,374$81K0.0%-68.2%0.007%
5/7/2026 Swiss National Bank22,100$531K0.0%N/A0.049%
5/5/2026 Bank of New York Mellon Corp58,709$1.41M0.0%+6.1%0.131%
4/27/2026 Y Intercept Hong Kong Ltd25,770$619K0.0%N/A0.057%
4/25/2026 Strs Ohio17,200$413K0.0%+17.8%0.038%
3/3/2026 Caitong International Asset Management Co. Ltd3,170$88K0.0%N/A0.007%
2/26/2026Seven Fleet Capital Management LP11,445$319K0.2%N/A0.026%
2/19/2026 Invesco Ltd.162,014$4.52M0.0%-8.5%0.362%
2/18/2026XTX Topco Ltd23,315$650K0.0%N/A0.052%
2/18/2026VARCOV Co.22,634$631K0.2%N/A0.051%
2/18/2026Virtus Investment Advisers LLC10,457$292K0.1%N/A0.023%
2/18/2026Tudor Investment Corp ET AL18,053$503K0.0%N/A0.040%
2/18/2026Numerai GP LLC45,866$1.28M0.2%N/A0.102%
2/18/2026Perceptive Advisors LLC433,160$12.08M0.2%-20.0%0.968%
2/18/2026Millennium Management LLC107,463$3.00M0.0%-72.0%0.240%
2/18/2026Balyasny Asset Management L.P.3,571$100K0.0%N/A0.008%
2/18/2026BVF Inc. IL1,720,782$47.98M1.6%-57.1%3.844%
2/17/2026Logos Global Management LP23,548$657K0.0%-71.8%0.053%
2/17/2026ADAR1 Capital Management LLC1,157,611$32.27M2.4%-1.6%2.586%
2/17/2026AQR Capital Management LLC7,826$218K0.0%N/A0.017%
2/17/2026First Light Asset Management LLC620,811$17.31M1.3%N/A1.387%
2/17/2026Trexquant Investment LP44,005$1.23M0.0%N/A0.098%
2/17/2026Jump Financial LLC8,399$234K0.0%N/A0.019%
2/17/2026Price T Rowe Associates Inc. MD25,443$710K0.0%-7.2%0.057%
2/17/2026Public Employees Retirement System of Ohio10,594$295K0.0%N/A0.024%
2/17/2026 Russell Investments Group Ltd.15,310$427K0.0%+707.5%0.034%
2/17/2026Atom Investors LP9,791$273K0.0%N/A0.022%
2/17/2026ExodusPoint Capital Management LP37,867$1.06M0.0%N/A0.085%
2/17/2026Graham Capital Management L.P.8,971$250K0.0%N/A0.020%
2/16/2026Squarepoint Ops LLC14,847$414K0.0%N/A0.033%
2/16/2026Barclays PLC38,147$1.06M0.0%+26.7%0.085%
2/13/2026Marshall Wace LLP226,901$6.33M0.0%N/A0.507%
2/13/2026Kalehua Capital Management LLC194,544$5.42M5.0%N/A0.435%
2/13/2026Bank of Nova Scotia8,300$231K0.0%N/A0.019%
2/13/2026Jacobs Levy Equity Management Inc.61,370$1.71M0.0%+71.5%0.137%
2/13/2026Siren L.L.C.2,000,000$55.76M1.7%-9.2%4.467%
2/13/2026State Street Corp540,028$15.06M0.0%+28.9%1.206%
2/13/2026Dynamic Technology Lab Private Ltd10,810$301K0.1%N/A0.024%
2/13/2026 Caitong International Asset Management Co. Ltd1,901$53K0.1%N/A0.004%
2/13/2026 Wells Fargo & Company MN26,529$740K0.0%+31.7%0.059%
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2/12/2026 Federated Hermes Inc.78,905$2.20M0.0%N/A0.176%
2/12/2026 New York State Common Retirement Fund5,600$156K0.0%+93.1%0.013%
2/12/2026 Nuveen LLC25,798$719K0.0%+7.7%0.058%
2/12/2026 Group One Trading LLC944$26K0.0%-111.8%0.002%
2/11/2026 Primecap Management Co. CA546,100$15.23M0.0%N/A1.220%
2/11/2026 Deutsche Bank AG14,879$415K0.0%+5.3%0.033%
2/11/2026 Franklin Resources Inc.16,852$470K0.0%N/A0.038%
2/11/2026 Los Angeles Capital Management LLC18,550$517K0.0%N/A0.041%
2/10/2026Goldman Sachs Group Inc.2,715,129$75.70M0.0%+86.6%6.065%
2/10/2026 Intech Investment Management LLC13,283$370K0.0%N/A0.030%
2/9/2026Geode Capital Management LLC572,734$15.97M0.0%+5.0%1.279%
2/6/2026Global Retirement Partners LLC1,256$35K0.0%N/A0.003%
2/6/2026 Covestor Ltd1,941$54K0.0%-46.4%0.004%
2/5/2026 Baader Bank Aktiengesellschaft10,000$279K0.0%N/A0.022%
2/2/2026 Strs Ohio14,600$407K0.0%N/A0.033%
1/29/2026 China Universal Asset Management Co. Ltd.10,296$287K0.0%N/A0.023%
1/26/2026 Mirae Asset Global Investments Co. Ltd.2,176$61K0.0%N/A0.005%
1/1/2026 JPMorgan Chase & Co.8,736$164K0.0%-13.5%0.020%
11/17/2025Jacobs Levy Equity Management Inc.35,778$673K0.0%N/A0.080%
11/17/2025 PharVision Advisers LLC11,932$224K0.1%+17.5%0.027%
11/17/2025VR Adviser LLC610,808$11.49M0.6%+13.0%1.364%
11/17/2025Verition Fund Management LLC20,131$379K0.0%N/A0.045%
11/17/2025Quarry LP1,736$33K0.0%-51.8%0.004%
11/17/2025Millennium Management LLC384,200$7.23M0.0%+639.6%0.858%
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.9,791$184K0.0%-16.3%0.022%
11/17/2025Checkpoint Capital L.P.283,158$5.33M1.8%-51.7%0.632%
11/17/2025Bank of America Corp DE51,495$969K0.0%-48.1%0.115%
11/14/2025ADAR1 Capital Management LLC1,176,491$22.13M2.1%+38.9%2.628%
11/14/2025Longaeva Partners L.P.57,064$1.07M0.2%N/A0.127%
11/14/2025Two Sigma Investments LP92,334$1.74M0.0%+18.9%0.206%
11/14/2025Avoro Capital Advisors LLC1,337,500$25.16M0.3%+8.1%2.987%
11/13/2025 Invesco Ltd.177,070$3.33M0.0%+1,396.4%0.397%
11/13/2025 UBS Group AG59,046$1.11M0.0%-18.4%0.132%
11/13/2025 BNP Paribas Financial Markets4,155$78K0.0%+88.0%0.009%
11/13/2025 Russell Investments Group Ltd.1,896$36K0.0%N/A0.004%
11/7/2025Vanguard Group Inc.1,518,757$28.57M0.0%+7.4%3.406%
11/7/2025 JPMorgan Chase & Co.8,736$164K0.0%-13.5%0.020%
11/6/2025 Rhumbline Advisers27,604$519K0.0%-3.4%0.062%
10/30/2025 Covestor Ltd3,620$68K0.0%+55.8%0.008%
8/15/2025Soleus Capital Management L.P.75,456$798K0.1%-90.0%0.169%
8/15/2025Rangeley Capital LLC58,605$619K0.8%+10.7%0.131%
8/15/2025Perceptive Advisors LLC541,450$5.72M0.5%N/A1.215%
8/15/2025Boothbay Fund Management LLC24,142$255K0.0%N/A0.054%
8/15/2025Bank of America Corp DE99,213$1.05M0.0%+758.3%0.223%
8/14/2025VR Adviser LLC540,453$5.71M0.4%N/A1.213%
8/13/2025CW Advisors LLC12,589$133K0.0%N/A0.028%
8/13/2025 PharVision Advisers LLC10,152$107K0.2%N/A0.023%
8/13/2025Sio Capital Management LLC584,435$6.18M2.4%-25.9%1.312%
8/13/2025Quadrature Capital Ltd10,125$107K0.0%N/A0.023%
8/12/2025XTX Topco Ltd22,330$236K0.0%-40.2%0.050%
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8/12/2025 Rhumbline Advisers28,572$302K0.0%+22.5%0.064%
8/12/2025 JPMorgan Chase & Co.10,101$107K0.0%+15.0%0.023%
8/11/2025 Universal Beteiligungs und Servicegesellschaft mbH222,702$2.35M0.0%+116.7%0.500%
8/8/2025 Intech Investment Management LLC12,200$129K0.0%N/A0.027%
8/8/2025Geode Capital Management LLC487,956$5.16M0.0%+19.1%1.095%
5/29/2025Rhumbline Advisers23,318$135K0.0%+16.6%0.052%
5/16/2025Woodline Partners LP582,585$3.37M0.0%+94.2%1.309%
5/16/2025Goldman Sachs Group Inc.1,449,399$8.39M0.0%-13.4%3.253%
5/16/2025Checkpoint Capital L.P.824,878$4.78M2.6%N/A1.853%
5/16/2025BVF Inc. IL4,396,124$25.45M1.0%+79.3%9.875%


SEPN Institutional Ownership - Frequently Asked Questions

During the previous two years, 111 institutional investors and hedge funds held shares of Septerna. The most heavily invested institutionals were RA Capital Management L.P. ($160.21M), TRV GP V LLC ($142.34M), Goldman Sachs Group Inc. ($75.70M), Samsara BioCapital LLC ($63.40M), Siren L.L.C. ($55.76M), BVF Inc. IL ($47.98M), and Deep Track Capital LP ($43.81M).Learn more on Septerna's institutional investors.

Of the 106 institutional investors that purchased Septerna's stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: RA Capital Management L.P. ($7.00M), TRV GP V LLC ($6.22M), BVF Inc. IL ($4.40M), TRV GP VI LLC ($4.21M), Driehaus Capital Management LLC ($3.12M), Samsara BioCapital LLC ($2.77M), and Deep Track Capital LP ($1.91M).

Institutional investors have bought a total of 10,580,257 shares in the last 24 months. This purchase volume represents approximately $163.29M in transactions.

Of the 21 institutional investors that sold Septerna's stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: BVF Inc. IL ($2.30M), Soleus Capital Management L.P. ($675.90K), Checkpoint Capital L.P. ($303.32K), Millennium Management LLC ($276.74K), Goldman Sachs Group Inc. ($224.96K), Sio Capital Management LLC ($204.24K), and Siren L.L.C. ($202.51K).

Institutional investors have sold a total of 4,479,266 shares in the last 24 months. This volume of shares sold represents approximately $101.02M in transactions.


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This page (NASDAQ:SEPN) was last updated on 5/14/2026 by MarketBeat.com Staff.
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