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Septerna (SEPN) Institutional Ownership

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$34.36 -1.57 (-4.37%)
Closing price 07/13/2026 04:00 PM Eastern
Extended Trading
$31.98 -2.38 (-6.94%)
As of 07/13/2026 07:58 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.
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Institutional Ownership Changes (13F Filings) for Septerna (NASDAQ:SEPN)

Number of
Institutional Buyers
(last 12 months)
68
Total
Institutional Inflows
(last 12 months)
$163.35M
Number of
Institutional Sellers
(last 12 months)
21
Total
Institutional Outflows
(last 12 months)
$102.25M
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SEPN Institutional Buying and Selling by Quarter

Septerna Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
5/19/2026Bank of America Corp DE25,973$624K0.0%-30.9%0.058%
5/19/2026Janus Henderson Group PLC890,754$21.33M0.0%N/A1.976%
5/18/2026ADAR1 Capital Management LLC1,089,818$26.19M1.5%-5.9%2.418%
5/16/2026First Light Asset Management LLC732,860$17.61M1.6%+18.0%1.626%
5/15/2026Rangeley Capital LLC39,800$956K0.9%-39.5%0.088%
5/14/2026Renaissance Technologies LLC37,700$906K0.0%N/A0.084%
5/14/2026Public Employees Retirement System of Ohio3,374$81K0.0%-68.2%0.007%
5/7/2026Swiss National Bank22,100$531K0.0%N/A0.049%
5/5/2026Bank of New York Mellon Corp58,709$1.41M0.0%+6.1%0.131%
4/27/2026Y Intercept Hong Kong Ltd25,770$619K0.0%N/A0.057%
4/25/2026Strs Ohio17,200$413K0.0%+17.8%0.038%
3/3/2026Caitong International Asset Management Co. Ltd3,170$88K0.0%N/A0.007%
2/26/2026Seven Fleet Capital Management LP11,445$319K0.2%N/A0.026%
2/19/2026Invesco Ltd.162,014$4.52M0.0%-8.5%0.362%
2/18/2026XTX Topco Ltd23,315$650K0.0%N/A0.052%
2/18/2026VARCOV Co.22,634$631K0.2%N/A0.051%
2/18/2026Virtus Investment Advisers LLC10,457$292K0.1%N/A0.023%
2/18/2026Tudor Investment Corp ET AL18,053$503K0.0%N/A0.040%
2/18/2026Numerai GP LLC45,866$1.28M0.2%N/A0.102%
2/18/2026Perceptive Advisors LLC433,160$12.08M0.2%-20.0%0.968%
2/18/2026Millennium Management LLC107,463$3.00M0.0%-72.0%0.240%
2/18/2026Balyasny Asset Management L.P.3,571$100K0.0%N/A0.008%
2/18/2026BVF Inc. IL1,720,782$47.98M1.6%-57.1%3.844%
2/17/2026Logos Global Management LP23,548$657K0.0%-71.8%0.053%
2/17/2026ADAR1 Capital Management LLC1,157,611$32.27M2.4%-1.6%2.586%
2/17/2026AQR Capital Management LLC7,826$218K0.0%N/A0.017%
2/17/2026First Light Asset Management LLC620,811$17.31M1.3%N/A1.387%
2/17/2026Trexquant Investment LP44,005$1.23M0.0%N/A0.098%
2/17/2026Jump Financial LLC8,399$234K0.0%N/A0.019%
2/17/2026Price T Rowe Associates Inc. MD25,443$710K0.0%-7.2%0.057%
2/17/2026Public Employees Retirement System of Ohio10,594$295K0.0%N/A0.024%
2/17/2026Russell Investments Group Ltd.15,310$427K0.0%+707.5%0.034%
2/17/2026Atom Investors LP9,791$273K0.0%N/A0.022%
2/17/2026ExodusPoint Capital Management LP37,867$1.06M0.0%N/A0.085%
2/17/2026Graham Capital Management L.P.8,971$250K0.0%N/A0.020%
2/16/2026Squarepoint Ops LLC14,847$414K0.0%N/A0.033%
2/16/2026Barclays PLC38,147$1.06M0.0%+26.7%0.085%
2/13/2026Marshall Wace LLP226,901$6.33M0.0%N/A0.507%
2/13/2026Kalehua Capital Management LLC194,544$5.42M5.0%N/A0.435%
2/13/2026Bank of Nova Scotia8,300$231K0.0%N/A0.019%
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2/13/2026Jacobs Levy Equity Management Inc.61,370$1.71M0.0%+71.5%0.137%
2/13/2026Siren L.L.C.2,000,000$55.76M1.7%-9.2%4.467%
2/13/2026State Street Corp540,028$15.06M0.0%+28.9%1.206%
2/13/2026Dynamic Technology Lab Private Ltd10,810$301K0.1%N/A0.024%
2/13/2026Caitong International Asset Management Co. Ltd1,901$53K0.1%N/A0.004%
2/13/2026Wells Fargo & Company MN26,529$740K0.0%+31.7%0.059%
2/12/2026Federated Hermes Inc.78,905$2.20M0.0%N/A0.176%
2/12/2026New York State Common Retirement Fund5,600$156K0.0%+93.1%0.013%
2/12/2026Nuveen LLC25,798$719K0.0%+7.7%0.058%
2/12/2026Group One Trading LLC944$26K0.0%-111.8%0.002%
2/11/2026Primecap Management Co. CA546,100$15.23M0.0%N/A1.220%
2/11/2026Deutsche Bank AG14,879$415K0.0%+5.3%0.033%
2/11/2026Franklin Resources Inc.16,852$470K0.0%N/A0.038%
2/11/2026Los Angeles Capital Management LLC18,550$517K0.0%N/A0.041%
2/10/2026Goldman Sachs Group Inc.2,715,129$75.70M0.0%+86.6%6.065%
2/10/2026Intech Investment Management LLC13,283$370K0.0%N/A0.030%
2/9/2026Geode Capital Management LLC572,734$15.97M0.0%+5.0%1.279%
2/6/2026Global Retirement Partners LLC1,256$35K0.0%N/A0.003%
2/6/2026Covestor Ltd1,941$54K0.0%-46.4%0.004%
2/5/2026Baader Bank Aktiengesellschaft10,000$279K0.0%N/A0.022%
2/2/2026Strs Ohio14,600$407K0.0%N/A0.033%
1/29/2026China Universal Asset Management Co. Ltd.10,296$287K0.0%N/A0.023%
1/26/2026Mirae Asset Global Investments Co. Ltd.2,176$61K0.0%N/A0.005%
1/1/2026JPMorgan Chase & Co.8,736$164K0.0%-13.5%0.020%
11/17/2025Jacobs Levy Equity Management Inc.35,778$673K0.0%N/A0.080%
11/17/2025PharVision Advisers LLC11,932$224K0.1%+17.5%0.027%
11/17/2025VR Adviser LLC610,808$11.49M0.6%+13.0%1.364%
11/17/2025Verition Fund Management LLC20,131$379K0.0%N/A0.045%
11/17/2025Quarry LP1,736$33K0.0%-51.8%0.004%
11/17/2025Millennium Management LLC384,200$7.23M0.0%+639.6%0.858%
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.9,791$184K0.0%-16.3%0.022%
11/17/2025Checkpoint Capital L.P.283,158$5.33M1.8%-51.7%0.632%
11/17/2025Bank of America Corp DE51,495$969K0.0%-48.1%0.115%
11/14/2025ADAR1 Capital Management LLC1,176,491$22.13M2.1%+38.9%2.628%
11/14/2025Longaeva Partners L.P.57,064$1.07M0.2%N/A0.127%
11/14/2025Two Sigma Investments LP92,334$1.74M0.0%+18.9%0.206%
11/14/2025Avoro Capital Advisors LLC1,337,500$25.16M0.3%+8.1%2.987%
11/13/2025Invesco Ltd.177,070$3.33M0.0%+1,396.4%0.397%
11/13/2025UBS Group AG59,046$1.11M0.0%-18.4%0.132%
11/13/2025BNP Paribas Financial Markets4,155$78K0.0%+88.0%0.009%
11/13/2025Russell Investments Group Ltd.1,896$36K0.0%N/A0.004%
11/7/2025Vanguard Group Inc.1,518,757$28.57M0.0%+7.4%3.406%
11/7/2025JPMorgan Chase & Co.8,736$164K0.0%-13.5%0.020%
11/6/2025Rhumbline Advisers27,604$519K0.0%-3.4%0.062%
10/30/2025Covestor Ltd3,620$68K0.0%+55.8%0.008%
8/15/2025Soleus Capital Management L.P.75,456$798K0.1%-90.0%0.169%
8/15/2025Rangeley Capital LLC58,605$619K0.8%+10.7%0.131%
8/15/2025Perceptive Advisors LLC541,450$5.72M0.5%N/A1.215%
8/15/2025Boothbay Fund Management LLC24,142$255K0.0%N/A0.054%
8/15/2025Bank of America Corp DE99,213$1.05M0.0%+758.3%0.223%
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8/14/2025VR Adviser LLC540,453$5.71M0.4%N/A1.213%
8/13/2025CW Advisors LLC12,589$133K0.0%N/A0.028%
8/13/2025PharVision Advisers LLC10,152$107K0.2%N/A0.023%
8/13/2025Sio Capital Management LLC584,435$6.18M2.4%-25.9%1.312%
8/13/2025Quadrature Capital Ltd10,125$107K0.0%N/A0.023%
8/12/2025XTX Topco Ltd22,330$236K0.0%-40.2%0.050%
8/12/2025Rhumbline Advisers28,572$302K0.0%+22.5%0.064%
8/12/2025JPMorgan Chase & Co.10,101$107K0.0%+15.0%0.023%
8/11/2025Universal Beteiligungs und Servicegesellschaft mbH222,702$2.35M0.0%+116.7%0.500%
8/8/2025Intech Investment Management LLC12,200$129K0.0%N/A0.027%


SEPN Institutional Ownership - Frequently Asked Questions

During the previous two years, 112 institutional investors and hedge funds held shares of Septerna. The most heavily invested institutionals were RA Capital Management L.P. ($160.21M), TRV GP V LLC ($142.34M), Goldman Sachs Group Inc. ($75.70M), Samsara BioCapital LLC ($63.40M), Siren L.L.C. ($55.76M), BVF Inc. IL ($47.98M), and Deep Track Capital LP ($43.81M).Learn more on Septerna's institutional investors.

Of the 107 institutional investors that purchased Septerna's stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: RA Capital Management L.P. ($7.00M), TRV GP V LLC ($6.22M), BVF Inc. IL ($4.40M), TRV GP VI LLC ($4.21M), Driehaus Capital Management LLC ($3.12M), Samsara BioCapital LLC ($2.77M), and Janus Henderson Group PLC ($1.99M).

Institutional investors have bought a total of 7,311,971 shares in the last 24 months. This purchase volume represents approximately $163.35M in transactions.

Of the 21 institutional investors that sold Septerna's stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: BVF Inc. IL ($2.30M), Soleus Capital Management L.P. ($675.90K), Checkpoint Capital L.P. ($303.32K), Millennium Management LLC ($276.74K), Sio Capital Management LLC ($204.24K), Siren L.L.C. ($202.51K), and Perceptive Advisors LLC ($108.29K).

Institutional investors have sold a total of 4,359,722 shares in the last 24 months. This volume of shares sold represents approximately $102.25M in transactions.


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This page (NASDAQ:SEPN) was last updated on 7/14/2026 by MarketBeat.com Staff.
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