Go Pro

Septerna (SEPN) Competitors

Septerna logo
$34.35 -2.99 (-8.01%)
As of 12:22 PM Eastern
This is a fair market value price provided by Massive. Learn more.

SEPN vs. CNTA, COGT, SRRK, BLTE, and CGON

Should you buy Septerna stock or one of its competitors? MarketBeat compares Septerna with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Septerna include Centessa Pharmaceuticals (CNTA), Cogent Biosciences (COGT), Scholar Rock (SRRK), Belite Bio (BLTE), and CG Oncology (CGON). These companies are all part of the "pharmaceutical products" industry.

How does Septerna compare to Centessa Pharmaceuticals?

Septerna (NASDAQ:SEPN) and Centessa Pharmaceuticals (NASDAQ:CNTA) are both medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, valuation, dividends, institutional ownership, risk, earnings, analyst recommendations and media sentiment.

Centessa Pharmaceuticals has a net margin of 0.00% compared to Septerna's net margin of -49.88%. Septerna's return on equity of -12.72% beat Centessa Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Septerna-49.88% -12.72% -8.87%
Centessa Pharmaceuticals N/A -60.37%-44.17%

Septerna has a beta of 2.39, meaning that its share price is 139% more volatile than the broader market. Comparatively, Centessa Pharmaceuticals has a beta of 1.11, meaning that its share price is 11% more volatile than the broader market.

82.0% of Centessa Pharmaceuticals shares are held by institutional investors. 5.8% of Septerna shares are held by insiders. Comparatively, 4.1% of Centessa Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Septerna has higher revenue and earnings than Centessa Pharmaceuticals. Septerna is trading at a lower price-to-earnings ratio than Centessa Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Septerna$45.95M33.70-$48.88M-$0.81N/A
Centessa PharmaceuticalsN/AN/A-$197.53M-$1.79N/A

Septerna presently has a consensus price target of $45.78, indicating a potential upside of 33.27%. Centessa Pharmaceuticals has a consensus price target of $41.33, indicating a potential upside of 2.06%. Given Septerna's stronger consensus rating and higher probable upside, equities analysts clearly believe Septerna is more favorable than Centessa Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Septerna
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Centessa Pharmaceuticals
1 Sell rating(s)
9 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.21

In the previous week, Septerna had 1 more articles in the media than Centessa Pharmaceuticals. MarketBeat recorded 5 mentions for Septerna and 4 mentions for Centessa Pharmaceuticals. Centessa Pharmaceuticals' average media sentiment score of 0.72 beat Septerna's score of 0.40 indicating that Centessa Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Septerna
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Centessa Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Septerna beats Centessa Pharmaceuticals on 12 of the 16 factors compared between the two stocks.

How does Septerna compare to Cogent Biosciences?

Cogent Biosciences (NASDAQ:COGT) and Septerna (NASDAQ:SEPN) are both medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, valuation, institutional ownership, risk, profitability, dividends, analyst recommendations and media sentiment.

In the previous week, Septerna had 3 more articles in the media than Cogent Biosciences. MarketBeat recorded 5 mentions for Septerna and 2 mentions for Cogent Biosciences. Septerna's average media sentiment score of 0.40 beat Cogent Biosciences' score of 0.38 indicating that Septerna is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Cogent Biosciences
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Septerna
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Septerna has higher revenue and earnings than Cogent Biosciences. Septerna is trading at a lower price-to-earnings ratio than Cogent Biosciences, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cogent BiosciencesN/AN/A-$328.94M-$2.17N/A
Septerna$45.95M33.70-$48.88M-$0.81N/A

Cogent Biosciences presently has a consensus price target of $43.73, indicating a potential upside of 15.53%. Septerna has a consensus price target of $45.78, indicating a potential upside of 33.27%. Given Septerna's stronger consensus rating and higher probable upside, analysts plainly believe Septerna is more favorable than Cogent Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cogent Biosciences
1 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
2 Strong Buy rating(s)
2.86
Septerna
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91

Cogent Biosciences has a net margin of 0.00% compared to Septerna's net margin of -49.88%. Septerna's return on equity of -12.72% beat Cogent Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Cogent BiosciencesN/A -104.27% -54.64%
Septerna -49.88%-12.72%-8.87%

Cogent Biosciences has a beta of 0.34, suggesting that its share price is 66% less volatile than the broader market. Comparatively, Septerna has a beta of 2.39, suggesting that its share price is 139% more volatile than the broader market.

Summary

Septerna beats Cogent Biosciences on 10 of the 13 factors compared between the two stocks.

How does Septerna compare to Scholar Rock?

Septerna (NASDAQ:SEPN) and Scholar Rock (NASDAQ:SRRK) are both medical companies, but which is the superior stock? We will compare the two companies based on the strength of their earnings, institutional ownership, media sentiment, risk, valuation, dividends, profitability and analyst recommendations.

Septerna has a beta of 2.39, meaning that its stock price is 139% more volatile than the broader market. Comparatively, Scholar Rock has a beta of 0.69, meaning that its stock price is 31% less volatile than the broader market.

Scholar Rock has a net margin of 0.00% compared to Septerna's net margin of -49.88%. Septerna's return on equity of -12.72% beat Scholar Rock's return on equity.

Company Net Margins Return on Equity Return on Assets
Septerna-49.88% -12.72% -8.87%
Scholar Rock N/A -163.52%-96.67%

91.1% of Scholar Rock shares are owned by institutional investors. 5.8% of Septerna shares are owned by insiders. Comparatively, 13.3% of Scholar Rock shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Septerna has higher revenue and earnings than Scholar Rock. Septerna is trading at a lower price-to-earnings ratio than Scholar Rock, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Septerna$45.95M33.70-$48.88M-$0.81N/A
Scholar RockN/AN/A-$377.94M-$3.59N/A

Septerna presently has a consensus price target of $45.78, indicating a potential upside of 33.27%. Scholar Rock has a consensus price target of $56.00, indicating a potential upside of 3.12%. Given Septerna's higher probable upside, equities analysts plainly believe Septerna is more favorable than Scholar Rock.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Septerna
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Scholar Rock
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
4 Strong Buy rating(s)
3.12

In the previous week, Septerna had 1 more articles in the media than Scholar Rock. MarketBeat recorded 5 mentions for Septerna and 4 mentions for Scholar Rock. Scholar Rock's average media sentiment score of 0.99 beat Septerna's score of 0.40 indicating that Scholar Rock is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Septerna
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Scholar Rock
0 Very Positive mention(s)
3 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Septerna and Scholar Rock tied by winning 8 of the 16 factors compared between the two stocks.

How does Septerna compare to Belite Bio?

Belite Bio (NASDAQ:BLTE) and Septerna (NASDAQ:SEPN) are both medical companies, but which is the better business? We will contrast the two businesses based on the strength of their media sentiment, risk, valuation, earnings, dividends, institutional ownership, profitability and analyst recommendations.

Belite Bio has a net margin of 0.00% compared to Septerna's net margin of -49.88%. Septerna's return on equity of -12.72% beat Belite Bio's return on equity.

Company Net Margins Return on Equity Return on Assets
Belite BioN/A -13.14% -12.88%
Septerna -49.88%-12.72%-8.87%

Belite Bio currently has a consensus target price of $203.00, suggesting a potential upside of 35.22%. Septerna has a consensus target price of $45.78, suggesting a potential upside of 33.27%. Given Belite Bio's higher probable upside, research analysts clearly believe Belite Bio is more favorable than Septerna.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Belite Bio
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.63
Septerna
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91

Septerna has higher revenue and earnings than Belite Bio. Belite Bio is trading at a lower price-to-earnings ratio than Septerna, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Belite BioN/AN/A-$77.61M-$2.53N/A
Septerna$45.95M33.70-$48.88M-$0.81N/A

0.5% of Belite Bio shares are owned by institutional investors. 13.3% of Belite Bio shares are owned by insiders. Comparatively, 5.8% of Septerna shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Belite Bio has a beta of -1.24, meaning that its stock price is 224% less volatile than the broader market. Comparatively, Septerna has a beta of 2.39, meaning that its stock price is 139% more volatile than the broader market.

In the previous week, Septerna had 3 more articles in the media than Belite Bio. MarketBeat recorded 5 mentions for Septerna and 2 mentions for Belite Bio. Belite Bio's average media sentiment score of 0.57 beat Septerna's score of 0.40 indicating that Belite Bio is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Belite Bio
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Septerna
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Septerna beats Belite Bio on 11 of the 16 factors compared between the two stocks.

How does Septerna compare to CG Oncology?

Septerna (NASDAQ:SEPN) and CG Oncology (NASDAQ:CGON) are both medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, institutional ownership, risk, earnings, media sentiment, profitability, valuation and dividends.

Septerna has higher revenue and earnings than CG Oncology. Septerna is trading at a lower price-to-earnings ratio than CG Oncology, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Septerna$45.95M33.70-$48.88M-$0.81N/A
CG Oncology$4.04M1,563.63-$160.99M-$2.33N/A

In the previous week, CG Oncology had 1 more articles in the media than Septerna. MarketBeat recorded 6 mentions for CG Oncology and 5 mentions for Septerna. Septerna's average media sentiment score of 0.40 beat CG Oncology's score of 0.07 indicating that Septerna is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Septerna
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
CG Oncology
1 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

CG Oncology has a net margin of 0.00% compared to Septerna's net margin of -49.88%. Septerna's return on equity of -12.72% beat CG Oncology's return on equity.

Company Net Margins Return on Equity Return on Assets
Septerna-49.88% -12.72% -8.87%
CG Oncology N/A -23.33%-22.24%

Septerna has a beta of 2.39, suggesting that its share price is 139% more volatile than the broader market. Comparatively, CG Oncology has a beta of 0.31, suggesting that its share price is 69% less volatile than the broader market.

Septerna currently has a consensus target price of $45.78, suggesting a potential upside of 33.27%. CG Oncology has a consensus target price of $81.73, suggesting a potential upside of 14.11%. Given Septerna's stronger consensus rating and higher possible upside, analysts clearly believe Septerna is more favorable than CG Oncology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Septerna
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
CG Oncology
1 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.71

26.6% of CG Oncology shares are owned by institutional investors. 5.8% of Septerna shares are owned by company insiders. Comparatively, 4.8% of CG Oncology shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Summary

Septerna beats CG Oncology on 11 of the 17 factors compared between the two stocks.

Get Septerna News Delivered to You Automatically

Sign up to receive the latest news and ratings for SEPN and its competitors with MarketBeat's FREE daily newsletter.

Subscribe Now
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.

New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SEPN and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Skip Chart

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Skip Chart

SEPN vs. The Competition

MetricSepternaMED IndustryMedical SectorNASDAQ Exchange
Market Cap$1.55B$3.63B$6.82B$12.35B
Dividend YieldN/A2.22%2.67%6.11%
P/E Ratio-42.4021.3425.8224.22
Price / Sales33.70340.74551.75101.49
Price / CashN/A62.1029.0936.93
Price / Book4.038.4810.906.43
Net Income-$48.88M$23.92M$3.58B$336.87M
7 Day Performance-1.43%2.94%2.42%0.27%
1 Month Performance13.74%0.50%0.14%-0.93%
1 Year Performance226.83%67.21%35.46%29.64%

Septerna Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SEPN
Septerna
2.3201 of 5 stars
$34.35
-8.0%
$45.78
+33.3%
+255.3%$1.55B$45.95MN/AN/A
CNTA
Centessa Pharmaceuticals
1.7044 of 5 stars
$40.50
+0.8%
$41.33
+2.1%
N/A$6.26B$15MN/A200
COGT
Cogent Biosciences
1.7555 of 5 stars
$36.31
+1.3%
$43.73
+20.4%
+436.8%$6.20BN/AN/A80
SRRK
Scholar Rock
1.634 of 5 stars
$51.27
+4.2%
$56.00
+9.2%
+52.9%$6.14BN/AN/A140
BLTE
Belite Bio
3.2604 of 5 stars
$145.09
-1.3%
$203.00
+39.9%
+151.9%$5.82BN/AN/A10

Related Companies and Tools


This page (NASDAQ:SEPN) was last updated on 6/29/2026 by MarketBeat.com Staff.
From Our Partners