| 09/24/2026 3:29 PM | 5AM CO-INVESTORS II LP (1390376) Reporting 5AM Partners II, LLC (1555952) Reporting 5AM Partners VII, LLC (1873545) Reporting 5AM Ventures II LP (1386509) Reporting 5AM Ventures VII, L.P. (1844435) Reporting DIEKMAN JOHN D (1240357) Reporting PARMAR KUSH (1664281) Reporting ROCKLAGE SCOTT M (1219014) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 09/24/2026 3:30 PM | 5AM Partners VII, LLC (1873545) Filed by Skye Bioscience (1516551) Subject | Form SCHEDULE 13D/A | |
| 09/24/2026 3:31 PM | Schwab Andrew J. (1598549) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 09/18/2026 5:37 PM | 5AM CO-INVESTORS II LP (1390376) Reporting 5AM Partners II, LLC (1555952) Reporting 5AM Partners VII, LLC (1873545) Reporting 5AM Ventures II LP (1386509) Reporting 5AM Ventures VII, L.P. (1844435) Reporting DIEKMAN JOHN D (1240357) Reporting PARMAR KUSH (1664281) Reporting ROCKLAGE SCOTT M (1219014) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 09/18/2026 5:39 PM | Schwab Andrew J. (1598549) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 09/11/2026 3:13 PM | Skye Bioscience (1516551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 09/11/2026 3:17 PM | Skye Bioscience (1516551) Filer | Form DEFA14A | |
| 08/24/2026 3:02 PM | Skye Bioscience (1516551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 08/24/2026 3:05 PM | Skye Bioscience (1516551) Filer | Form DEFA14A | |
| 08/20/2026 4:57 PM | 5AM CO-INVESTORS II LP (1390376) Reporting 5AM Partners II, LLC (1555952) Reporting 5AM Partners VII, LLC (1873545) Reporting 5AM Ventures II LP (1386509) Reporting 5AM Ventures VII, L.P. (1844435) Reporting DIEKMAN JOHN D (1240357) Reporting PARMAR KUSH (1664281) Reporting ROCKLAGE SCOTT M (1219014) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 08/20/2026 4:59 PM | Schwab Andrew J. (1598549) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
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| 08/19/2026 8:42 PM | Skye Bioscience (1516551) Filer | Form 8-K/A | |
| 08/19/2026 8:43 PM | Skye Bioscience (1516551) Filer | Form DEFA14A | |
| 08/18/2026 6:57 PM | 5AM Partners VII, LLC (1873545) Filed by Skye Bioscience (1516551) Subject | Form SCHEDULE 13D/A | |
| 08/14/2026 9:18 AM | Skye Bioscience (1516551) Filer | Form DEFA14A | |
| 08/14/2026 8:40 AM | Skye Bioscience (1516551) Filer | Form 10-Q General form for quarterly reports under Section 13 or 15(d) | |
| 08/14/2026 8:36 AM | Skye Bioscience (1516551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 08/07/2026 4:37 PM | DHILLON PUNIT (1425052) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/28/2026 7:37 PM | Sharp John P (1342894) Reporting Skye Bioscience (1516551) Issuer | Form 3 Initial statement of beneficial ownership of securities | |
| 04/16/2026 7:02 AM | Skye Bioscience (1516551) Filer | Form DEF 14A | |
| 04/16/2026 7:02 AM | Skye Bioscience (1516551) Filer | Form DEFA14A | |
| 04/16/2026 7:04 AM | Skye Bioscience (1516551) Filer | Form ARS | |
| 04/06/2026 4:15 PM | Skye Bioscience (1516551) Filer | Form PRE 14A | |
| 04/06/2026 3:10 PM | Skye Bioscience (1516551) Filer | Form 8-K/A | |
| 04/06/2026 3:15 PM | Skye Bioscience (1516551) Filer | Form PREM14A | |
| 04/03/2026 3:46 PM | Skye Bioscience (1516551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 04/03/2026 3:46 PM | Skye Bioscience (1516551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 04/02/2026 5:15 PM | Grayson Paul A. (1861554) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/02/2026 5:17 PM | Charych Deborah H. (1965700) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/02/2026 5:18 PM | Diep Tuan Tu (2013809) Reporting Skye Bioscience (1516551) Issuer | Form 3/A | |
| 04/02/2026 5:20 PM | Jenkins Annalisa (1639481) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/02/2026 5:21 PM | Skye Bioscience (1516551) Issuer Twitty Christopher (1870121) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/02/2026 5:22 PM | Skye Bioscience (1516551) Issuer Smith Karen L. (1639637) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/02/2026 5:06 PM | DHILLON PUNIT (1425052) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/02/2026 5:07 PM | Diep Tuan Tu (2013809) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 04/02/2026 5:13 PM | Schwab Andrew J. (1598549) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 03/19/2026 4:19 PM | Skye Bioscience (1516551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 02/09/2026 8:06 PM | Schwab Andrew J. (1598549) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/09/2026 7:54 PM | DHILLON PUNIT (1425052) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/09/2026 7:54 PM | Arora Puneet S. (2035933) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/09/2026 7:54 PM | Diep Tuan Tu (2013809) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
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| 02/09/2026 7:54 PM | Jenkins Annalisa (1639481) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/09/2026 7:54 PM | Charych Deborah H. (1965700) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/09/2026 7:54 PM | Skye Bioscience (1516551) Issuer Twitty Christopher (1870121) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/09/2026 7:54 PM | ARSENAULT KAITLYN (1877242) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/09/2026 7:54 PM | Skye Bioscience (1516551) Issuer Smith Karen L. (1639637) Reporting | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/09/2026 7:54 PM | Grayson Paul A. (1861554) Reporting Skye Bioscience (1516551) Issuer | Form 4 Statement of changes in beneficial ownership of securities | |
| 02/02/2026 6:04 AM | Skye Bioscience (1516551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 12/23/2025 3:04 PM | Skye Bioscience (1516551) Filer | Form 8-K Current report pursuant to Section 13 or 15(d) | |
| 12/16/2025 3:30 PM | 5AM Partners VII, LLC (1873545) Filed by Skye Bioscience (1516551) Subject | Form SCHEDULE 13D/A | |