Do analysts prefer THAR or SKYE?

Skye Bioscience has a consensus price target of $9.80, suggesting a potential upside of 1,236.61%. Given Skye Bioscience's stronger consensus rating and higher possible upside, analysts clearly believe Skye Bioscience is more favorable than Tharimmune. Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Tharimmune 1 Sell rating(s) 0 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 1.00 Skye Bioscience 1 Sell rating(s) 2 Hold rating(s) 3 Buy rating(s) 1 Strong Buy rating(s) 2.57

Which has better valuation & earnings, THAR or SKYE?

Tharimmune is trading at a lower price-to-earnings ratio than Skye Bioscience, indicating that it is currently the more affordable of the two stocks. Company Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio Tharimmune N/A N/A -$12.20M -$3.99 N/A Skye Bioscience N/A N/A -$55.92M -$1.44 N/A

Is THAR or SKYE more profitable?

Skye Bioscience's return on equity of -217.27% beat Tharimmune's return on equity. Company Net Margins Return on Equity Return on Assets Tharimmune N/A -588.45% -264.41% Skye Bioscience N/A -217.27% -162.39%

Which has stronger valuation & earnings, PEPG or SKYE?

PepGen is trading at a lower price-to-earnings ratio than Skye Bioscience, indicating that it is currently the more affordable of the two stocks. Company Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio PepGen N/A N/A -$89.65M -$1.75 N/A Skye Bioscience N/A N/A -$55.92M -$1.44 N/A

Is PEPG or SKYE more profitable?

PepGen's return on equity of -59.89% beat Skye Bioscience's return on equity. Company Net Margins Return on Equity Return on Assets PepGen N/A -59.89% -49.62% Skye Bioscience N/A -217.27% -162.39%

Which has stronger valuation and earnings, SKYE or BMEA?

Biomea Fusion is trading at a lower price-to-earnings ratio than Skye Bioscience, indicating that it is currently the more affordable of the two stocks. Company Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio Skye Bioscience N/A N/A -$55.92M -$1.44 N/A Biomea Fusion N/A N/A -$61.80M -$0.68 N/A

Is SKYE or BMEA more profitable?

Skye Bioscience's return on equity of -217.27% beat Biomea Fusion's return on equity. Company Net Margins Return on Equity Return on Assets Skye Bioscience N/A -217.27% -162.39% Biomea Fusion N/A -265.37% -103.96%

Skye Bioscience (SKYE) Competitors

$0.73 -0.04 (-5.37%)

Closing price 06/5/2026 04:00 PM Eastern

Extended Trading

$0.74 +0.01 (+0.93%)

As of 06/5/2026 07:57 PM Eastern

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SKYE vs. THAR, PEPG, VRCA, CRDF, and BMEA

Should you buy Skye Bioscience stock or one of its competitors? MarketBeat compares Skye Bioscience with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Skye Bioscience include Tharimmune (THAR), PepGen (PEPG), Verrica Pharmaceuticals (VRCA), Cardiff Oncology (CRDF), and Biomea Fusion (BMEA). These companies are all part of the "pharmaceutical products" industry.

How does Skye Bioscience compare to Tharimmune?

Tharimmune (NASDAQ:THAR) and Skye Bioscience (NASDAQ:SKYE) are both small-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their dividends, earnings, risk, analyst recommendations, valuation, institutional ownership, profitability and media sentiment.

In the previous week, Tharimmune's average media sentiment score of 0.00 equaled Skye Bioscience'saverage media sentiment score.

Company	Overall Sentiment
Tharimmune	Neutral
Skye Bioscience	Neutral

Tharimmune has a beta of 1.43, indicating that its stock price is 43% more volatile than the broader market. Comparatively, Skye Bioscience has a beta of 2.95, indicating that its stock price is 195% more volatile than the broader market.

Skye Bioscience has a consensus price target of $9.80, suggesting a potential upside of 1,236.61%. Given Skye Bioscience's stronger consensus rating and higher possible upside, analysts clearly believe Skye Bioscience is more favorable than Tharimmune.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Tharimmune	1 Sell rating(s)	0 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.00
Skye Bioscience	1 Sell rating(s)	2 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.57

Tharimmune is trading at a lower price-to-earnings ratio than Skye Bioscience, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Tharimmune	N/A	N/A	-$12.20M	-$3.99	N/A
Skye Bioscience	N/A	N/A	-$55.92M	-$1.44	N/A

1.2% of Tharimmune shares are held by institutional investors. Comparatively, 21.1% of Skye Bioscience shares are held by institutional investors. 6.7% of Tharimmune shares are held by company insiders. Comparatively, 6.2% of Skye Bioscience shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Skye Bioscience's return on equity of -217.27% beat Tharimmune's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Tharimmune	N/A	-588.45%	-264.41%
Skye Bioscience	N/A	-217.27%	-162.39%

Summary

Skye Bioscience beats Tharimmune on 10 of the 12 factors compared between the two stocks.

How does Skye Bioscience compare to PepGen?

PepGen (NASDAQ:PEPG) and Skye Bioscience (NASDAQ:SKYE) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their dividends, institutional ownership, valuation, profitability, earnings, risk, analyst recommendations and media sentiment.

58.0% of PepGen shares are held by institutional investors. Comparatively, 21.1% of Skye Bioscience shares are held by institutional investors. 1.3% of PepGen shares are held by company insiders. Comparatively, 6.2% of Skye Bioscience shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

PepGen's return on equity of -59.89% beat Skye Bioscience's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
PepGen	N/A	-59.89%	-49.62%
Skye Bioscience	N/A	-217.27%	-162.39%

In the previous week, PepGen had 2 more articles in the media than Skye Bioscience. MarketBeat recorded 2 mentions for PepGen and 0 mentions for Skye Bioscience. PepGen's average media sentiment score of 0.00 equaled Skye Bioscience'saverage media sentiment score.

Company	Overall Sentiment
PepGen	Neutral
Skye Bioscience	Neutral

PepGen has a beta of 1.93, suggesting that its stock price is 93% more volatile than the broader market. Comparatively, Skye Bioscience has a beta of 2.95, suggesting that its stock price is 195% more volatile than the broader market.

PepGen currently has a consensus price target of $11.60, indicating a potential upside of 722.70%. Skye Bioscience has a consensus price target of $9.80, indicating a potential upside of 1,236.61%. Given Skye Bioscience's higher probable upside, analysts plainly believe Skye Bioscience is more favorable than PepGen.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
PepGen	1 Sell rating(s)	0 Hold rating(s)	5 Buy rating(s)	0 Strong Buy rating(s)	2.67
Skye Bioscience	1 Sell rating(s)	2 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.57

PepGen is trading at a lower price-to-earnings ratio than Skye Bioscience, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
PepGen	N/A	N/A	-$89.65M	-$1.75	N/A
Skye Bioscience	N/A	N/A	-$55.92M	-$1.44	N/A

Summary

Skye Bioscience beats PepGen on 7 of the 13 factors compared between the two stocks.

How does Skye Bioscience compare to Verrica Pharmaceuticals?

Skye Bioscience (NASDAQ:SKYE) and Verrica Pharmaceuticals (NASDAQ:VRCA) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their institutional ownership, dividends, profitability, risk, valuation, earnings, analyst recommendations and media sentiment.

Skye Bioscience has a beta of 2.95, meaning that its share price is 195% more volatile than the broader market. Comparatively, Verrica Pharmaceuticals has a beta of 1.49, meaning that its share price is 49% more volatile than the broader market.

Verrica Pharmaceuticals has higher revenue and earnings than Skye Bioscience. Verrica Pharmaceuticals is trading at a lower price-to-earnings ratio than Skye Bioscience, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Skye Bioscience	N/A	N/A	-$55.92M	-$1.44	N/A
Verrica Pharmaceuticals	$35.58M	2.92	-$17.89M	-$1.03	N/A

In the previous week, Verrica Pharmaceuticals had 2 more articles in the media than Skye Bioscience. MarketBeat recorded 2 mentions for Verrica Pharmaceuticals and 0 mentions for Skye Bioscience. Skye Bioscience's average media sentiment score of 0.00 equaled Verrica Pharmaceuticals'average media sentiment score.

Company	Overall Sentiment
Skye Bioscience	Neutral
Verrica Pharmaceuticals	Neutral

Skye Bioscience has a net margin of 0.00% compared to Verrica Pharmaceuticals' net margin of -47.97%. Skye Bioscience's return on equity of -217.27% beat Verrica Pharmaceuticals' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Skye Bioscience	N/A	-217.27%	-162.39%
Verrica Pharmaceuticals	-47.97%	-1,077.78%	-40.76%

21.1% of Skye Bioscience shares are owned by institutional investors. Comparatively, 42.5% of Verrica Pharmaceuticals shares are owned by institutional investors. 6.2% of Skye Bioscience shares are owned by insiders. Comparatively, 54.0% of Verrica Pharmaceuticals shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Skye Bioscience currently has a consensus price target of $9.80, indicating a potential upside of 1,236.61%. Verrica Pharmaceuticals has a consensus price target of $14.50, indicating a potential upside of 140.07%. Given Skye Bioscience's stronger consensus rating and higher possible upside, equities analysts plainly believe Skye Bioscience is more favorable than Verrica Pharmaceuticals.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Skye Bioscience	1 Sell rating(s)	2 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.57
Verrica Pharmaceuticals	1 Sell rating(s)	1 Hold rating(s)	2 Buy rating(s)	0 Strong Buy rating(s)	2.25

Summary

Skye Bioscience beats Verrica Pharmaceuticals on 8 of the 15 factors compared between the two stocks.

How does Skye Bioscience compare to Cardiff Oncology?

Skye Bioscience (NASDAQ:SKYE) and Cardiff Oncology (NASDAQ:CRDF) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their profitability, institutional ownership, valuation, earnings, dividends, media sentiment, risk and analyst recommendations.

Skye Bioscience currently has a consensus target price of $9.80, indicating a potential upside of 1,236.61%. Cardiff Oncology has a consensus target price of $8.75, indicating a potential upside of 483.33%. Given Skye Bioscience's stronger consensus rating and higher probable upside, research analysts clearly believe Skye Bioscience is more favorable than Cardiff Oncology.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Skye Bioscience	1 Sell rating(s)	2 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.57
Cardiff Oncology	1 Sell rating(s)	4 Hold rating(s)	4 Buy rating(s)	0 Strong Buy rating(s)	2.33

Cardiff Oncology has higher revenue and earnings than Skye Bioscience. Cardiff Oncology is trading at a lower price-to-earnings ratio than Skye Bioscience, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Skye Bioscience	N/A	N/A	-$55.92M	-$1.44	N/A
Cardiff Oncology	$590K	173.82	-$45.85M	-$0.67	N/A

In the previous week, Cardiff Oncology had 6 more articles in the media than Skye Bioscience. MarketBeat recorded 6 mentions for Cardiff Oncology and 0 mentions for Skye Bioscience. Skye Bioscience's average media sentiment score of 0.00 beat Cardiff Oncology's score of -0.44 indicating that Skye Bioscience is being referred to more favorably in the media.

Company	Overall Sentiment
Skye Bioscience	Neutral
Cardiff Oncology	Neutral

Skye Bioscience has a net margin of 0.00% compared to Cardiff Oncology's net margin of -8,527.43%. Cardiff Oncology's return on equity of -95.51% beat Skye Bioscience's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Skye Bioscience	N/A	-217.27%	-162.39%
Cardiff Oncology	-8,527.43%	-95.51%	-71.47%

Skye Bioscience has a beta of 2.95, suggesting that its share price is 195% more volatile than the broader market. Comparatively, Cardiff Oncology has a beta of 1.36, suggesting that its share price is 36% more volatile than the broader market.

21.1% of Skye Bioscience shares are held by institutional investors. Comparatively, 16.3% of Cardiff Oncology shares are held by institutional investors. 6.2% of Skye Bioscience shares are held by company insiders. Comparatively, 8.5% of Cardiff Oncology shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Summary

Skye Bioscience and Cardiff Oncology tied by winning 8 of the 16 factors compared between the two stocks.

How does Skye Bioscience compare to Biomea Fusion?

Skye Bioscience (NASDAQ:SKYE) and Biomea Fusion (NASDAQ:BMEA) are both small-cap medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their valuation, risk, earnings, institutional ownership, media sentiment, analyst recommendations, profitability and dividends.

Skye Bioscience has a beta of 2.95, indicating that its share price is 195% more volatile than the broader market. Comparatively, Biomea Fusion has a beta of -0.31, indicating that its share price is 131% less volatile than the broader market.

In the previous week, Biomea Fusion had 4 more articles in the media than Skye Bioscience. MarketBeat recorded 4 mentions for Biomea Fusion and 0 mentions for Skye Bioscience. Biomea Fusion's average media sentiment score of 0.50 beat Skye Bioscience's score of 0.00 indicating that Biomea Fusion is being referred to more favorably in the news media.

Company	Overall Sentiment
Skye Bioscience	Neutral
Biomea Fusion	Neutral

Skye Bioscience's return on equity of -217.27% beat Biomea Fusion's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Skye Bioscience	N/A	-217.27%	-162.39%
Biomea Fusion	N/A	-265.37%	-103.96%

Biomea Fusion is trading at a lower price-to-earnings ratio than Skye Bioscience, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Skye Bioscience	N/A	N/A	-$55.92M	-$1.44	N/A
Biomea Fusion	N/A	N/A	-$61.80M	-$0.68	N/A

Skye Bioscience presently has a consensus target price of $9.80, suggesting a potential upside of 1,236.61%. Biomea Fusion has a consensus target price of $8.50, suggesting a potential upside of 569.29%. Given Skye Bioscience's higher probable upside, equities research analysts clearly believe Skye Bioscience is more favorable than Biomea Fusion.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Skye Bioscience	1 Sell rating(s)	2 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.57
Biomea Fusion	1 Sell rating(s)	0 Hold rating(s)	7 Buy rating(s)	0 Strong Buy rating(s)	2.75

21.1% of Skye Bioscience shares are held by institutional investors. Comparatively, 96.7% of Biomea Fusion shares are held by institutional investors. 6.2% of Skye Bioscience shares are held by insiders. Comparatively, 10.6% of Biomea Fusion shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Summary

Biomea Fusion beats Skye Bioscience on 8 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SKYE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

SKYE vs. The Competition

Export

Metric	Skye Bioscience	MED Industry	Medical Sector	NASDAQ Exchange
Market Cap	$25.77M	$3.34B	$6.66B	$11.99B
Dividend Yield	N/A	2.30%	2.67%	5.56%
P/E Ratio	-0.51	18.69	24.03	23.62
Price / Sales	N/A	300.27	513.89	111.51
Price / Cash	N/A	51.45	26.99	37.22
Price / Book	1.18	7.97	10.24	6.66
Net Income	-$55.92M	$23.89M	$3.57B	$337.55M
7 Day Performance	-5.44%	-6.96%	-1.28%	-2.52%
1 Month Performance	-18.38%	-2.80%	1.38%	-0.03%
1 Year Performance	-69.89%	36.80%	23.93%	25.34%

Skye Bioscience Competitors List

Export

Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
SKYE Skye Bioscience	1.5951 of 5 stars	$0.73 -5.4%	$9.80 +1,236.6%	-69.9%	$25.77M	N/A	N/A	11	Gap Down
THAR Tharimmune	N/A	$2.81 -9.5%	N/A	+52.3%	$105.83M	N/A	N/A	2
PEPG PepGen	2.5702 of 5 stars	$1.45 -1.4%	$11.60 +700.0%	-6.0%	$101.68M	N/A	N/A	30	Analyst Downgrade
VRCA Verrica Pharmaceuticals	2.364 of 5 stars	$5.79 -1.9%	$14.50 +150.4%	-1.2%	$101.36M	$35.58M	N/A	40	News Coverage Gap Up
CRDF Cardiff Oncology	1.9508 of 5 stars	$1.51 +2.0%	$10.10 +568.9%	-61.3%	$101.19M	$590K	N/A	20	Analyst Downgrade Gap Down High Trading Volume

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This page (NASDAQ:SKYE) was last updated on 6/7/2026 by MarketBeat.com Staff.

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Skye Bioscience (SKYE) Competitors

SKYE vs. THAR, PEPG, VRCA, CRDF, and BMEA

How does Skye Bioscience compare to Tharimmune?

Summary

How does Skye Bioscience compare to PepGen?

Summary

How does Skye Bioscience compare to Verrica Pharmaceuticals?

Summary

How does Skye Bioscience compare to Cardiff Oncology?

Summary

How does Skye Bioscience compare to Biomea Fusion?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

SKYE vs. The Competition

Skye Bioscience Competitors List

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Stock Ideas and Recommendations

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Skye Bioscience (SKYE) Competitors

SKYE vs. THAR, PEPG, VRCA, CRDF, and BMEA

How does Skye Bioscience compare to Tharimmune?

Does the media favor THAR or SKYE?

Which has more volatility and risk, THAR or SKYE?

Do analysts prefer THAR or SKYE?

Which has better valuation & earnings, THAR or SKYE?

Do insiders and institutionals hold more shares of THAR or SKYE?

Is THAR or SKYE more profitable?

Summary

How does Skye Bioscience compare to PepGen?

Do insiders & institutionals believe in PEPG or SKYE?

Is PEPG or SKYE more profitable?

Does the media favor PEPG or SKYE?

Which has more risk and volatility, PEPG or SKYE?

Do analysts recommend PEPG or SKYE?

Which has stronger valuation & earnings, PEPG or SKYE?

Summary

How does Skye Bioscience compare to Verrica Pharmaceuticals?

Which has more volatility & risk, SKYE or VRCA?

Which has higher valuation and earnings, SKYE or VRCA?

Does the media refer more to SKYE or VRCA?

Is SKYE or VRCA more profitable?

Do institutionals & insiders believe in SKYE or VRCA?

Do analysts recommend SKYE or VRCA?

Summary

How does Skye Bioscience compare to Cardiff Oncology?

Do analysts rate SKYE or CRDF?

Which has stronger valuation and earnings, SKYE or CRDF?

Does the media prefer SKYE or CRDF?

Is SKYE or CRDF more profitable?

Which has more risk & volatility, SKYE or CRDF?

Do insiders & institutionals believe in SKYE or CRDF?

Summary

How does Skye Bioscience compare to Biomea Fusion?

Which has more risk and volatility, SKYE or BMEA?

Does the media refer more to SKYE or BMEA?

Is SKYE or BMEA more profitable?

Which has stronger valuation and earnings, SKYE or BMEA?

Do analysts rate SKYE or BMEA?

Do insiders and institutionals believe in SKYE or BMEA?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

SKYE vs. The Competition

Skye Bioscience Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools