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NASDAQ:SNDX

Syndax Pharmaceuticals (SNDX) Stock Price, News & Analysis

Syndax Pharmaceuticals logo
$17.62 -0.06 (-0.34%)
As of 09/18/2026 04:00 PM Eastern

About Syndax Pharmaceuticals Stock (NASDAQ:SNDX)

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Key Stats

Today's Range
$17.37
$17.95
50-Day Range
$17.28
$24.13
52-Week Range
$12.99
$25.59
Volume
5.18 million shs
Average Volume
1.36 million shs
Market Capitalization
$1.56 billion
P/E Ratio
N/A
Dividend Yield
N/A
Price Target
$42.30
Consensus Rating
Moderate Buy

Company Overview

Syndax Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company focused on developing and delivering therapies for cancer and other serious diseases. The company’s research has centered on medicines that target disease-driving biological pathways, including genetically defined forms of leukemia and immune-related conditions.

Syndax’s lead product is Revuforj (revumenib), an oral menin inhibitor approved by the U.S. Food and Drug Administration for certain adults and children with relapsed or refractory acute leukemia involving a KMT2A translocation. The company continues to evaluate revumenib in additional leukemia settings and in combination with other cancer treatments.

Syndax has also developed axatilimab, a monoclonal antibody designed to inhibit the colony-stimulating factor 1 receptor, or CSF-1R. The therapy has been investigated for chronic graft-versus-host disease and other diseases involving abnormal immune-cell activity and tissue fibrosis. Syndax is headquartered in Waltham, Massachusetts, and its development and commercial activities are primarily focused on the United States while it pursues broader opportunities for its medicines. Michael A. Metzger serves as the company’s chief executive officer.

AI Generated. May Contain Errors.

Syndax Pharmaceuticals Stock Analysis - MarketRank™

See Top-Rated MarketRank™ Stocks
69th Percentile Overall Score

SNDX MarketRank™: 

Syndax Pharmaceuticals scored higher than 69% of companies evaluated by MarketBeat, and ranked 267th out of 905 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

  • Consensus Rating

    Syndax Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.82, and is based on no strong buy ratings, 10 buy ratings, no hold ratings, and 1 sell rating.

  • Upside Potential

    Syndax Pharmaceuticals has a consensus price target of $42.30, representing about 140.1% upside from its current price of $17.62.

  • Amount of Analyst Coverage

    Syndax Pharmaceuticals has been the subject of 5 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

  • Read more about Syndax Pharmaceuticals' stock forecast and price target.
  • Earnings Growth

    Earnings for Syndax Pharmaceuticals are expected to grow in the coming year, from ($2.01) to ($0.98) per share.

  • Price to Earnings Ratio vs. the Market

    The P/E ratio of Syndax Pharmaceuticals is -7.02, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Earnings Ratio vs. Sector

    The P/E ratio of Syndax Pharmaceuticals is -7.02, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Book Value per Share Ratio

    Syndax Pharmaceuticals has a P/B Ratio of 23.81. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

  • Read more about Syndax Pharmaceuticals' valuation and earnings.
  • Percentage of Shares Shorted

    25.70% of the float of Syndax Pharmaceuticals has been sold short.
  • Short Interest Ratio / Days to Cover

    Syndax Pharmaceuticals has a short interest ratio ("days to cover") of 19.65, which indicates bearish sentiment.
  • Change versus previous month

    Short interest in Syndax Pharmaceuticals has recently decreased by 5.33%, indicating that investor sentiment is improving significantly.
  • Dividend Yield

    Syndax Pharmaceuticals does not currently pay a dividend.

  • Dividend Growth

    Syndax Pharmaceuticals does not have a long track record of dividend growth.

  • News Sentiment

    Syndax Pharmaceuticals has a news sentiment score of 0.88. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.56 average news sentiment score of Healthcare companies.
  • News Coverage This Week

    MarketBeat has tracked 4 news articles for Syndax Pharmaceuticals this week, compared to 5 articles on an average week.
  • Search Interest

    8 people have searched for SNDX on MarketBeat in the last 30 days. This is an increase of 167% compared to the previous 30 days.
  • MarketBeat Follows

    3 people have added Syndax Pharmaceuticals to their MarketBeat watchlist in the last 30 days.
  • Insider Buying vs. Insider Selling

    In the past three months, Syndax Pharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $784,770.00 in company stock.

  • Percentage Held by Insiders

    4.80% of the stock of Syndax Pharmaceuticals is held by insiders.

  • Percentage Held by Institutions

    Syndax Pharmaceuticals has minimal institutional ownership at this time.

  • Read more about Syndax Pharmaceuticals' insider trading history.
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SNDX Stock News Headlines

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Syndax (SNDX) Q2 2026 Earnings Call Transcript
See More Headlines

SNDX Stock Analysis - Frequently Asked Questions

Syndax Pharmaceuticals' stock was trading at $21.01 on January 1st, 2026. Since then, SNDX stock has decreased by 16.1% and is now trading at $17.62.

Syndax Pharmaceuticals, Inc. (NASDAQ:SNDX) issued its earnings results on Tuesday, August, 4th. The company reported ($0.55) earnings per share (EPS) for the quarter, missing the consensus estimate of ($0.45) by $0.10. The company's quarterly revenue was up 91.8% compared to the same quarter last year.
Read the conference call transcript
.

Syndax Pharmaceuticals (SNDX) raised $66 million in an IPO on Thursday, March 3rd 2016. The company issued 4,400,000 shares at a price of $14.00-$16.00 per share. Morgan Stanley and Citigroup acted as the underwriters for the IPO and JMP Securities and Oppenheimer & Co. were co-managers.

Top institutional investors of Syndax Pharmaceuticals include BlackRock Inc. (10.18%), Bank of America Corp DE (4.57%), Elmind Capital LP (2.09%) and Trails Edge Capital Partners LP (1.25%). Insiders that own company stock include Michael A Metzger, Dennis Podlesak, Keith A Goldan, Neil Gallagher and Nicholas AJ Botwood.
View institutional ownership trends
.

Shares of SNDX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

Based on aggregate information from My MarketBeat watchlists, some other companies that Syndax Pharmaceuticals investors own include NVIDIA (NVDA), Broadcom (AVGO), Meta Platforms (META), Arista Networks (ANET), Adobe (ADBE), Novo Nordisk A/S (NVO) and ServiceNow (NOW).

Company Calendar

Last Earnings
8/04/2026
Today
9/18/2026
Next Earnings (Estimated)
11/02/2026
Fiscal Year End
12/31/2026

Industry, Sector and Symbol

Stock Exchange
NASDAQ
Industry
Biotechnology
Sub-Industry
Biotechnology
Current Symbol
NASDAQ:SNDX
CIK
1395937
Employees
298
Year Founded
2005

Price Target and Rating

High Price Target
$57.00
Low Price Target
$33.00
Potential Upside/Downside
+140.1%
Consensus Rating
Moderate Buy
Rating Score (0-4)
2.82
Research Coverage
11 Analysts

Profitability

EPS (Trailing Twelve Months)
($2.51)
Trailing P/E Ratio
N/A
Forward P/E Ratio
N/A
P/E Growth
N/A
Net Income
-$285.42 million
Net Margins
-87.52%
Pretax Margin
-87.52%
Return on Equity
-372.94%
Return on Assets
-39.11%

Debt

Debt-to-Equity Ratio
38.95
Current Ratio
6.77
Quick Ratio
6.44

Sales & Book Value

Annual Sales
$172.35 million
Price / Sales
9.06
Cash Flow
N/A
Price / Cash Flow
N/A
Book Value
$0.74 per share
Price / Book
23.81

Miscellaneous

Outstanding Shares
88,610,000
Free Float
84,357,000
Market Cap
$1.56 billion
Optionable
Optionable
Beta
0.37

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This page (NASDAQ:SNDX) was last updated on 9/19/2026 by MarketBeat.com Staff.
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