NASDAQ:SNSE Sensei Biotherapeutics (SNSE) Stock Price, News & Analysis $17.79 +0.23 (+1.31%) Closing price 05/22/2026 04:00 PM EasternExtended Trading$17.76 -0.02 (-0.14%) As of 05/22/2026 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Sensei Biotherapeutics Stock (NASDAQ:SNSE) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Sensei Biotherapeutics alerts:Sign Up Key Stats Today's Range$17.29▼$19.1650-Day Range$16.77▼$34.7952-Week Range$5.31▼$36.76Volume21,119 shsAverage Volume31,864 shsMarket Capitalization$23.84 millionP/E RatioN/ADividend YieldN/APrice Target$45.00Consensus RatingHold Company Overview Sensei Biotherapeutics, Inc. is a clinical-stage biotechnology company focused on the discovery and development of immunotherapies that harness both the innate and adaptive arms of the immune system to treat cancer and autoimmune diseases. Utilizing proprietary antibody engineering and biologics platforms, Sensei aims to develop next-generation checkpoint modulators and immune agonists designed to overcome the limitations of current therapies. The company’s lead programs include SIS-100, a first-in-class antagonist targeting Siglec-15 being evaluated in solid tumors to relieve immune suppression in the tumor microenvironment, and SIS-101, an antibody directed against CD39 intended to restore T-cell function by modulating adenosine signaling pathways. In addition to these clinical-stage candidates, Sensei is advancing preclinical projects against novel innate immune checkpoints and exploring combination regimens to broaden therapeutic impact. Founded in 2018 and headquartered in Cambridge, Massachusetts, Sensei Biotherapeutics operates across the United States and collaborates with academic and industry partners to accelerate research and development. The company’s leadership team brings extensive experience in antibody therapeutics, translational research and clinical development, supporting its mission to bring innovative immunotherapies through clinical trials and deliver new treatment options for patients worldwide.AI Generated. May Contain Errors. Read More Sensei Biotherapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks59th Percentile Overall ScoreSNSE MarketRank™: Sensei Biotherapeutics scored higher than 59% of companies evaluated by MarketBeat, and ranked 390th out of 866 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.9 / 5Analyst RatingHold Consensus RatingSensei Biotherapeutics has received a consensus rating of Hold. The company's average rating score is 2.20, and is based on no strong buy ratings, 2 buy ratings, 2 hold ratings, and 1 sell rating.Upside PotentialSensei Biotherapeutics has a consensus price target of $45.00, representing about 153.0% upside from its current price of $17.79.Amount of Analyst CoverageSensei Biotherapeutics has only been the subject of 4 research reports in the past 90 days.Read more about Sensei Biotherapeutics' stock forecast and price target. Earnings and Valuation0.0 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Sensei Biotherapeutics are expected to decrease in the coming year, from ($2.77) to ($3.77) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Sensei Biotherapeutics is -0.12, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Sensei Biotherapeutics is -0.12, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Read more about Sensei Biotherapeutics' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted81.01% of the float of Sensei Biotherapeutics has been sold short.Short Interest Ratio / Days to CoverSensei Biotherapeutics has a short interest ratio ("days to cover") of 27.08, which indicates bearish sentiment.Change versus previous monthShort interest in Sensei Biotherapeutics has recently decreased by 2.50%, indicating that investor sentiment is improving. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldSensei Biotherapeutics does not currently pay a dividend.Dividend GrowthSensei Biotherapeutics does not have a long track record of dividend growth. News and Social Media2.6 / 5News Sentiment0.20 News SentimentSensei Biotherapeutics has a news sentiment score of 0.20. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.45 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 9 news articles for Sensei Biotherapeutics this week, compared to 2 articles on an average week.Search Interest7 people have searched for SNSE on MarketBeat in the last 30 days. This is an increase of 600% compared to the previous 30 days. Company Ownership3.7 / 5Insider TradingAcquiring Shares Net Insider BuyingOver the last three months, insiders have purchased a net $637,230.00 in company stock, which represents 2.6731% of the company's market cap.Insider Buying vs. Insider SellingIn the past three months, Sensei Biotherapeutics insiders have bought 90.46% more of their company's stock than they have sold. Specifically, they have bought $1,341,669.00 in company stock and sold $704,439.00 in company stock.Percentage Held by Insiders23.20% of the stock of Sensei Biotherapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions10.50% of the stock of Sensei Biotherapeutics is held by institutions.Read more about Sensei Biotherapeutics' insider trading history. Receive SNSE Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Sensei Biotherapeutics and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. 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That is the scale of what analysts are calling the biggest AI IPO in history.And right now, you can claim a stake before the company goes public, starting with just $500.Elon Musk is predicting this investment could climb 1,000x from here. Early access is available today.May 23 at 1:00 AM | Brownstone Research (Ad)Sensei Biotherapeutics (NASDAQ:SNSE) Major Shareholder Acquires $164,021.22 in StockMay 18, 2026 | americanbankingnews.comSensei Biotherapeutics (NASDAQ:SNSE) Major Shareholder Sells $246,231.92 in StockMay 18, 2026 | americanbankingnews.comSensei Biotherapeutics (NASDAQ:SNSE) Major Shareholder Purchases $407,691.81 in StockMay 18, 2026 | americanbankingnews.comInsider Buying: Sensei Biotherapeutics (NASDAQ:SNSE) Major Shareholder Buys $212,975.75 in StockMay 18, 2026 | americanbankingnews.comSensei Biotherapeutics (NASDAQ:SNSE) Major Shareholder Purchases $164,021.22 in StockMay 16, 2026 | insidertrades.comSee More Headlines SNSE Stock Analysis - Frequently Asked Questions How have SNSE shares performed this year? Sensei Biotherapeutics' stock was trading at $10.67 at the beginning of 2026. Since then, SNSE shares have increased by 66.7% and is now trading at $17.79. How were Sensei Biotherapeutics' earnings last quarter? Sensei Biotherapeutics, Inc. (NASDAQ:SNSE) released its quarterly earnings results on Friday, May, 15th. The company reported ($131.45) earnings per share for the quarter, missing analysts' consensus estimates of ($0.62) by $130.83. When did Sensei Biotherapeutics' stock split? Sensei Biotherapeutics's stock reverse split on the morning of Tuesday, June 17th 2025.The 1-20 reverse split was announced on Friday, June 13th 2025. The number of shares owned by shareholders was adjusted after the closing bell on Monday, June 16th 2025. An investor that had 100 shares of stock prior to the reverse split would have 5 shares after the split. When did Sensei Biotherapeutics IPO? Sensei Biotherapeutics (SNSE) raised $100 million in an initial public offering (IPO) on Friday, February 5th 2021. The company issued 5,900,000 shares at a price of $16.00-$18.00 per share. Citigroup, Piper Sandler, Berenberg and Oppenheimer & Co. served as the underwriters for the IPO. Who are Sensei Biotherapeutics' major shareholders? Sensei Biotherapeutics' top institutional investors include Vivo Capital LLC (53.88%), Stempoint Capital LP (9.92%), Bank of America Corp DE (2.46%) and Renaissance Technologies LLC (2.39%). Insiders that own company stock include James Peyer, Millennium Management Llc, John Celebi and Apeiron Investment Group Ltd. View institutional ownership trends. How do I buy shares of Sensei Biotherapeutics? Shares of SNSE stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Sensei Biotherapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Sensei Biotherapeutics investors own include NVIDIA (NVDA), Micron Technology (MU), Tesla (TSLA), Advanced Micro Devices (AMD), Plug Power (PLUG), PayPal (PYPL) and Walt Disney (DIS). Company Calendar Last Earnings5/15/2026Today5/23/2026Next Earnings (Estimated)8/04/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (5d) 1-Year History May 25 Aug 25 Nov 25 Feb 26 May 26 As of 5 days ago, SNSE's financial health entered the Yellow zone, according to TradeSmith. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:SNSE CIK1829802 Webwww.senseibio.com Phone240-243-8000FaxN/AEmployees40Year Founded1999Price Target and Rating Average Price Target for Sensei Biotherapeutics$45.00 High Price Target$55.00 Low Price Target$30.00 Potential Upside/Downside+153.0%Consensus RatingHold Rating Score (0-4)2.20 Research Coverage5 Analysts Profitability EPS (Trailing Twelve Months)($142.72) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$21.08 million Net MarginsN/A Pretax MarginN/A Return on Equity-803.00% Return on Assets-256.50% Debt Debt-to-Equity RatioN/A Current Ratio14.39 Quick Ratio5.06 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value($102.30) per share Price / Book-0.17Miscellaneous Outstanding Shares1,340,000Free Float1,031,000Market Cap$23.84 million OptionableNot Optionable Beta-0.18 Social Links 10 Stocks Powering The Next AI Boom The AI boom is creating opportunities across semiconductors, cloud computing, enterprise software, infrastructure, cybersecurity, and automation. Inside this report, you’ll find 10 companies positioned to benefit as artificial intelligence moves from hype to real-world deployment and becomes a core growth driver for corporate America.Get This Free Report This page (NASDAQ:SNSE) was last updated on 5/23/2026 by MarketBeat.com Staff. 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