Spruce Biosciences (SPRB) Institutional Ownership $7.60 -0.35 (-4.40%) As of 08/26/2025 Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Spruce Biosciences (NASDAQ:SPRB)CurrentInstitutional OwnershipPercentage91.71%Number ofInstitutional Buyers(last 12 months)1TotalInstitutional Inflows(last 12 months)$9.10MNumber ofInstitutional Sellers(last 12 months)1TotalInstitutional Outflows(last 12 months)$6.42M Get SPRB Insider Trade Alerts Want to know when executives and insiders are buying or selling Spruce Biosciences stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily. 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Skip Chart & View Institutional Buying and Selling Data SPRB Institutional Buying and Selling by Quarter Spruce Biosciences Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails2/14/2025 Boothbay Fund Management LLC288,800$121K0.0%N/A0.699% 2/13/2025 Renaissance Technologies LLC405,900$170K0.0%-33.4%0.983% 8/16/2024 Almitas Capital LLC396,506$205K0.1%N/A0.964% 8/9/2024 Renaissance Technologies LLC366,100$190K0.0%+35.1%0.890% 8/6/2024 Acadian Asset Management LLC1,367,997$707K0.0%+270.9%3.324% 5/16/2024 AWM Investment Company Inc.200,000$157K0.0%N/A0.486% 5/10/2024 Acadian Asset Management LLC368,831$289K0.0%N/A0.896% 4/25/2024 Rosalind Advisors Inc.1,508,419$1.19M1.1%-4.9%3.666% 2/14/2024 Superstring Capital Management LP118,814$348K0.2%N/A0.292% 2/13/2024 Armistice Capital LLC2,230,000$6.53M0.1%-27.0%5.478% Get the Latest News and Ratings for SPRB and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Spruce Biosciences and its competitors with MarketBeat's FREE daily newsletter. 2/12/2024 AIGH Capital Management LLC2,123,863$6.22M2.5%+75.4%5.217% 2/9/2024 Worth Venture Partners LLC526,933$1.54M0.8%+74.4%1.294% 11/15/2023 Worth Venture Partners LLC302,074$683K0.4%+8.8%0.742% 11/15/2023 Armistice Capital LLC3,056,000$6.91M0.1%-12.6%7.507% 11/13/2023 AIGH Capital Management LLC1,211,000$2.74M1.3%+9.0%2.975% 7/26/2023 Privium Fund Management B.V.24,554$52K0.0%N/A0.062% 5/15/2023 AIGH Capital Management LLC1,104,000$2.37M0.9%N/A2.778% 5/5/2023 Carlyle Group Inc.2,896,518$6.40M0.2%N/A7.287% 5/3/2023 Privium Fund Management UK Ltd24,554$53K0.0%-51.3%0.062% 5/1/2023 Virtu Financial LLC13,722$30K0.0%N/A0.035% 5/1/2023 Marquette Asset Management LLC55,757$123K0.0%-18.4%0.140% 4/27/2023RiverVest Venture Management LLC2,936,281$6.49M7.5%+36.7%7.387% 2/13/2023 BML Capital Management LLC221,830$243K0.2%N/A0.942% 2/9/2023 Privium Fund Management UK Ltd50,400$55K0.0%N/A0.214% 1/12/2023 Marquette Asset Management LLC68,357$75K0.0%+6.7%0.290% 11/14/2022Ergoteles LLC23,032$32K0.0%-45.0%0.098% 11/10/2022Abingworth LLP1,792,518$2.47M0.8%N/A7.608% 10/18/2022 Bailard Inc.21,166$29K0.0%N/A0.090% 7/15/2022 Marquette Asset Management LLC64,090$112K0.0%+56.9%0.273% 2/10/2022 Acadian Asset Management LLC71,756$318K0.0%N/A0.306% 1/19/2022 Marquette Asset Management LLC40,853$182K0.0%N/A0.174% 11/16/2021 Laurion Capital Management LP11,337$68K0.0%-24.2%0.048% 11/15/2021 Deerfield Management Company L.P. Series C2,200,000$13.22M0.3%+7.5%9.411% 11/15/2021 Rock Springs Capital Management LP1,617,601$9.72M0.2%+0.8%6.919% 11/15/2021Caas Capital Management LP27,546$166K0.0%-70.2%0.118% 11/12/2021 Trexquant Investment LP11,998$72K0.0%N/A0.051% 11/10/2021Granite Point Capital Management L.P.63,614$382K0.0%-36.4%0.272% 11/8/2021 State Board of Administration of Florida Retirement System17,440$105K0.0%N/A0.075% 11/4/2021 Sands Capital Ventures LLC787,007$4.73M0.7%N/A3.366% 8/17/2021Caas Capital Management LP92,412$1.04M0.0%N/A0.395% This is my Christian duty (Ad)“This land I will give to you…” — a 4,000-year-old line from Genesis may hold the key to unlocking a $150 trillion vault of untapped American wealth. Former CIA advisor Jim Rickards calls it the “Old Testament Wealth Code” — and says it could transform your financial future. He’s revealing everything in a new presentation.Watch Jim Rickards reveal the Old Testament Wealth Code8/16/2021 California State Teachers Retirement System12,006$135K0.0%+14.0%0.051% 8/16/2021 Alyeska Investment Group L.P.19,413$218K0.0%N/A0.083% 8/16/2021 State Street Corp124,918$1.40M0.0%+31.8%0.534% 8/16/2021Nuveen Asset Management LLC29,616$332K0.0%+159.3%0.127% 8/16/2021 Goldman Sachs Group Inc.10,770$121K0.0%-13.5%0.046% 8/13/2021 Northern Trust Corp77,864$873K0.0%+2.3%0.334% 8/13/2021 Laurion Capital Management LP14,957$168K0.0%-25.2%0.064% 8/13/2021 Geode Capital Management LLC128,546$1.44M0.0%+17.3%0.551% 8/13/2021 Vanguard Group Inc.369,520$4.14M0.0%+96.0%1.584% 8/13/2021 FMR LLC1,185,673$13.29M0.0%-0.8%5.082% 8/12/2021 JPMorgan Chase & Co.163,857$1.84M0.0%-9.0%0.702% 8/11/2021 Bank of New York Mellon Corp25,566$286K0.0%+33.3%0.110% 8/11/2021BlackRock Inc.419,789$4.71M0.0%+21.6%1.799% (Data available from 1/1/2016 forward) SPRB Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of SPRB shares? During the previous two years, 10 institutional investors and hedge funds held shares of Spruce Biosciences. The most heavily invested institutionals were Armistice Capital LLC ($6.53M), AIGH Capital Management LLC ($6.22M), Worth Venture Partners LLC ($1.54M), Rosalind Advisors Inc. ($1.19M), Acadian Asset Management LLC ($707K), Superstring Capital Management LP ($348K), and Almitas Capital LLC ($205K).Learn more on Spruce Biosciences' institutional investors. What percentage of Spruce Biosciences' stock is owned by institutional investors? 91.71% of Spruce Biosciences' stock is owned by institutional investors. Learn more on SPRB's institutional investor holdings. Which institutional investors have been buying Spruce Biosciences' stock? The following institutional investors have purchased Spruce Biosciences' stock in the last 24 months: Acadian Asset Management LLC ($1.37M), AIGH Capital Management LLC ($1.01M), Almitas Capital LLC ($396.51K), Boothbay Fund Management LLC ($288.80K), Worth Venture Partners LLC ($249.31K), AWM Investment Company Inc. ($200K), and Superstring Capital Management LP ($118.81K). How much institutional buying is happening at Spruce Biosciences? Institutional investors have bought a total of 288,800 shares in the last 24 months. This purchase volume represents approximately $9.10M in transactions. Which of Spruce Biosciences' major shareholders have been selling company stock? The following institutional investors have sold Spruce Biosciences stock in the last 24 months: Renaissance Technologies LLC ($203.80K). How much institutional selling is happening at Spruce Biosciences? Institutional investors have sold a total of 203,800 shares in the last 24 months. This volume of shares sold represents approximately $6.42M in transactions. 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