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Spruce Biosciences (SPRB) 10K Form and Latest SEC Filings 2026

Spruce Biosciences logo
$48.25 -3.16 (-6.15%)
Closing price 05/19/2026 04:00 PM Eastern
Extended Trading
$49.81 +1.56 (+3.23%)
As of 05/19/2026 05:55 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

Latest Spruce Biosciences SEC Filings & Recent Activity

Spruce Biosciences (NASDAQ:SPRB) has submitted 227+ documents to the U.S. Securities and Exchange Commission (SEC) since 2020. For investors, these filings are the primary source of verified financial data — covering everything from annual revenue and debt levels in the 10-K, to material business events in 8-K current reports, to insider buying and selling activity in Form 4 disclosures. The most recent filing was a Form SCHEDULE 13G/A submitted on May 15, 2026.

Form 4
SPRUCE BIOSCIENCES, INC. Reports Ownership Change on Mar. 9, 2026

Form 4 filings disclose changes in stock ownership by company insiders, including purchases, sales, grants, and option exercises.

View insider ownership

8-K
Spruce Biosciences Files Current Report on May. 13, 2026

An 8-K is filed when a material corporate event occurs, such as an acquisition, leadership change, or financial update.

View filing

10-Q
Spruce Biosciences Files Quarterly Report on May. 13, 2026

The 10-Q contains Spruce Biosciences's unaudited quarterly financial statements, revenue, earnings updates, and cash flow changes between annual reports.

View earnings history

Spruce Biosciences SEC Filing History

Browse Spruce Biosciences' complete SEC filing history using the filters below. Filter by form type - 10-K, 10-Q, 8-K, Form 4, and more - or set a custom date range to find a filing.

DateFilerForm TypeView
05/15/2026 3:47 PM
Alyeska Investment Group, L.P. (1453072) Filed by
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G/A
05/15/2026 11:02 AM
Spruce Biosciences (1683553) Subject
Squadron Capital Management LLC (2050709) Filed by
Form SCHEDULE 13G/A
05/15/2026 6:24 AM
Spruce Biosciences (1683553) Subject
WELLINGTON MANAGEMENT GROUP LLP (902219) Filed by
Form SCHEDULE 13G/A
05/13/2026 3:06 PM
Spruce Biosciences (1683553) Filer
Form 10-Q
General form for quarterly reports under Section 13 or 15(d)  
05/13/2026 7:05 AM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
05/07/2026 4:13 PM
Ikarian Capital, LLC (1778253) Filed by
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G/A
04/21/2026 4:23 PM
Spruce Biosciences (1683553) Filer
Form 424B5
04/20/2026 3:02 PM
Spruce Biosciences (1683553) Filer
Form 424B5
04/09/2026 4:06 PM
Spruce Biosciences (1683553) Filer
Form ARS
04/09/2026 4:02 PM
Spruce Biosciences (1683553) Filer
Form DEF 14A
04/09/2026 4:04 PM
Spruce Biosciences (1683553) Filer
Form DEFA14A
03/20/2026 4:04 PM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
03/09/2026 3:07 PM
Hooks Corwin Dale (1665347) Reporting
Spruce Biosciences (1683553) Issuer
Form 3
Initial statement of beneficial ownership of securities  
03/09/2026 3:08 PM
Hooks Corwin Dale (1665347) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
03/09/2026 6:29 AM
Spruce Biosciences (1683553) Filer
Form S-8
Registration statement under Securities Act of 1933 to be offered to employees pursuant to certain plans  
03/09/2026 6:31 AM
Spruce Biosciences (1683553) Filer
Form 424B5
03/09/2026 6:21 AM
Spruce Biosciences (1683553) Filer
Form 10-K
Annual report pursuant to Section 13 or 15(d)  
03/09/2026 6:23 AM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
02/24/2026 3:47 PM
INTEGRATED CORE STRATEGIES (0) US
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G
02/17/2026 7:16 PM
ADAR1 Capital Management, LLC (1940272) Filed by
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G
02/17/2026 11:27 AM
Spruce Biosciences (1683553) Subject
Squadron Capital Management LLC (2050709) Filed by
Form SCHEDULE 13G/A
02/10/2026 10:19 AM
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G
02/05/2026 3:11 PM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
01/08/2026 7:05 AM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
01/05/2026 3:43 PM
Spruce Biosciences (1683553) Issuer
Szwarcberg Javier B. (1903669) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
12/17/2025 3:56 PM
Spruce Biosciences (1683553) Issuer
Szwarcberg Javier B. (1903669) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
12/17/2025 3:58 PM
Gharib Samir M. (1533302) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
12/15/2025 5:52 PM
Spruce Biosciences (1683553) Issuer
Szwarcberg Javier B. (1903669) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
12/15/2025 5:54 PM
Gharib Samir M. (1533302) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
12/15/2025 5:58 PM
GREY MICHAEL G (1240122) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
12/15/2025 6:00 PM
SPIEGELMAN DANIEL K (1238403) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
12/15/2025 5:50 PM
SIMPSON CAMILLA V (1822557) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
12/15/2025 5:44 PM
Spruce Biosciences (1683553) Issuer
Walbert Keli (2051489) Reporting
Form 3
Initial statement of beneficial ownership of securities  
12/15/2025 5:46 PM
Spruce Biosciences (1683553) Issuer
Walbert Keli (2051489) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
12/15/2025 5:47 PM
Barretto-Ko Percival (1978654) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
12/15/2025 7:05 AM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
12/12/2025 6:03 PM
Spruce Biosciences (1683553) Issuer
Szwarcberg Javier B. (1903669) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
12/12/2025 6:05 PM
Gharib Samir M. (1533302) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
12/12/2025 3:03 PM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
12/12/2025 3:08 PM
Spruce Biosciences (1683553) Filer
Form 424B3
11/27/2025 11:15 PM
Spruce Biosciences (1683553) Filer
Form EFFECT
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11/27/2025 11:15 PM
Spruce Biosciences (1683553) Filer
Form EFFECT
11/07/2025 3:30 PM
Ikarian Capital, LLC (1778253) Filed by
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G/A
10/29/2025 4:15 PM
Spruce Biosciences (1683553) Filer
Form S-3
Registration statement under Securities Act of 1933  
10/29/2025 4:17 PM
Spruce Biosciences (1683553) Filer
Form S-3
Registration statement under Securities Act of 1933  
10/22/2025 3:15 PM
Spruce Biosciences (1683553) Issuer
Szwarcberg Javier B. (1903669) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
10/22/2025 3:15 PM
Gharib Samir M. (1533302) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
10/16/2025 5:34 PM
Spruce Biosciences (1683553) Filer
Form D
Notice of Exempt Offering of Securities 
10/16/2025 4:10 PM
CITADEL ADVISORS LLC (1423053) Filed by
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G
10/15/2025 3:30 PM
Martinez Gregory (2091748) Reporting
Parkman Healthcare Partners LLC (1777015) Reporting
Spruce Biosciences (1683553) Issuer
Form 3
Initial statement of beneficial ownership of securities  
10/15/2025 3:32 PM
Martinez Gregory (2091748) Reporting
Parkman Healthcare Partners LLC (1777015) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
10/15/2025 2:11 PM
Spruce Biosciences (1683553) Subject
Squadron Capital Management LLC (2050709) Filed by
Form SCHEDULE 13G
10/09/2025 4:33 PM
HealthCap VIII, L.P. (1783281) Filed by
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13D/A
10/08/2025 7:53 PM
Parkman Healthcare Partners LLC (1777015) Reporting
Spruce Biosciences (1683553) Issuer
Form 3
Initial statement of beneficial ownership of securities  
10/08/2025 7:55 PM
Parkman Healthcare Partners LLC (1777015) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
10/08/2025 3:07 PM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
10/08/2025 10:04 AM
Ikarian Capital, LLC (1778253) Filed by
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G
08/14/2025 3:10 PM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
08/13/2025 3:26 PM
Radoff Bradley Louis (1380585) Filed by
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G/A
08/13/2025 3:31 PM
Rock Springs Capital Management LP (1595725) Filed by
Spruce Biosciences (1683553) Subject
Form SCHEDULE 13G/A
07/24/2025 6:30 PM
Muralidhar Bali (1784138) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/24/2025 6:34 PM
Spruce Biosciences (1683553) Issuer
Ways Kirk (1869391) Reporting
Form 4
Statement of changes in beneficial ownership of securities  
07/24/2025 6:35 PM
Aynechi Tiba (1669220) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/24/2025 6:36 PM
Barretto-Ko Percival (1978654) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/24/2025 6:36 PM
GREY MICHAEL G (1240122) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/24/2025 6:38 PM
SIMPSON CAMILLA V (1822557) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
07/24/2025 6:38 PM
SPIEGELMAN DANIEL K (1238403) Reporting
Spruce Biosciences (1683553) Issuer
Form 4
Statement of changes in beneficial ownership of securities  
06/12/2025 7:05 AM
Spruce Biosciences (1683553) Filer
Form DEFA14A
06/12/2025 7:10 AM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
05/29/2025 6:00 AM
Spruce Biosciences (1683553) Filer
Form 8-K
Current report pursuant to Section 13 or 15(d)  
(Data available from 1/1/2016 forward)

Spruce Biosciences SEC Filings - Frequently Asked Questions

Spruce Biosciences (SPRB) has submitted 227+ filings to the SEC since 2020. You can browse the complete history or filter by form type using the tools above.

Spruce Biosciences's fiscal year ends on December 31. The company typically files its 10-K annual report by the end of February, covering the prior fiscal year's financial results.

The most recent filing was a Form SCHEDULE 13G/A submitted on May 15, 2026. View the full filing using the link above.

SEC Filing Types: 10-K, 10-Q, 8-K and More

SEC filings are legally required disclosures that public companies submit to the U.S. Securities and Exchange Commission. Unlike press releases or earnings call transcripts, these documents are filed under legal obligation — meaning the financial data they contain is audited, standardized, and subject to penalties if materially false. For investors, that makes SEC filings the most reliable primary source available for evaluating a company's true financial position.

Yes. All SEC filings are publicly available through the SEC's EDGAR database and on financial research platforms like MarketBeat. Companies are required by law to make these disclosures accessible to all investors — meaning retail investors have access to the same source documents as institutional analysts.

A 10-K is an annual report containing audited financial statements and a full review of the company's business — it is the most comprehensive filing a company makes each year. A 10-Q is a shorter, unaudited quarterly update filed three times per year between annual reports. Investors typically use the 10-K for deep fundamental analysis and the 10-Q to track whether the company is on pace with its guidance mid-year.

The most important filing for fundamental investors. Filed once per year, the 10-K contains audited financial statements, revenue and earnings trends, debt obligations, risk factors, and management's own assessment of the business. Reading the risk factors section and comparing year-over-year financials can reveal issues that don't show up in analyst summaries.

An unaudited financial update filed three times per year (the 10-K covers Q4). Investors use 10-Qs to track whether guidance is on pace, monitor changes in cash flow or inventory, and catch any mid-year shifts in business conditions before they become headline news.

Filed within four business days of a material event — earnings releases, merger announcements, executive departures, or major asset sales. Because 8-Ks are filed before media coverage catches up, they are often the fastest way to get unfiltered information directly from the company on market-moving events.

Filed within two business days whenever an executive or director buys or sells company stock. Insider purchases — especially large or clustered buys — are often interpreted as a signal of management confidence. Insider selling is more ambiguous but worth monitoring for patterns, particularly around lock-up expirations or ahead of major announcements.


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This page (NASDAQ:SPRB) was last updated on 5/20/2026 by MarketBeat.com Staff.
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