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Spero Therapeutics (SPRO) Institutional Ownership

Spero Therapeutics logo
$1.98 +0.13 (+7.03%)
Closing price 08/27/2025 04:00 PM Eastern
Extended Trading
$2.03 +0.05 (+2.47%)
As of 07:04 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.
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Institutional Ownership Changes (13F Filings) for Spero Therapeutics (NASDAQ:SPRO)

Current
Institutional Ownership
Percentage
25.60%
Number of
Institutional Buyers
(last 12 months)
17
Total
Institutional Inflows
(last 12 months)
$4.73M
Number of
Institutional Sellers
(last 12 months)
6
Total
Institutional Outflows
(last 12 months)
$449.15K
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SPRO Institutional Buying and Selling by Quarter

Spero Therapeutics Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
8/15/2025 Bridgeway Capital Management LLC114,800$333K0.0%-25.8%0.204%
8/13/2025 Stonepine Capital Management LLC156,888$455K0.4%N/A0.281%
8/13/2025 Invesco Ltd.14,968$43K0.0%N/A0.027%
8/13/2025 Quadrature Capital Ltd31,205$90K0.0%N/A0.056%
8/12/2025 XTX Topco Ltd34,551$100K0.0%N/A0.062%
8/8/2025 Geode Capital Management LLC510,699$1.48M0.0%-2.7%0.913%
7/28/2025 Axxcess Wealth Management LLC32,548$94K0.0%N/A0.058%
7/7/2025 Capital Asset Advisory Services LLC32,548$94K0.0%N/A0.058%
5/28/2025 Anson Funds Management LP3,798,932$2.74M0.4%-1.1%6.795%
5/21/2025 Acadian Asset Management LLC871,212$626K0.0%-16.2%1.558%
5/14/2025 Anson Funds Management LP7,638,818$5.50M0.8%+98.9%13.662%
5/7/2025 Mackenzie Financial Corp209,031$151K0.0%+11.4%0.374%
2/20/2025 Mackenzie Financial Corp187,559$193K0.0%+487.9%0.344%
2/17/2025 Squarepoint Ops LLC55,051$57K0.0%N/A0.101%
2/17/2025 Anson Funds Management LP3,839,886$3.96M0.4%+2.4%7.043%
2/14/2025 Jane Street Group LLC52,869$54K0.0%N/A0.097%
2/14/2025 Northern Trust Corp86,447$89K0.0%-22.5%0.159%
2/14/2025 Three Seasons Wealth LLC30,000$31K0.0%N/A0.055%
2/13/2025 XTX Topco Ltd30,138$31K0.0%N/A0.055%
2/13/2025 Renaissance Technologies LLC1,105,591$1.14M0.0%+13.4%2.028%
2/13/2025 ADAR1 Capital Management LLC801,277$825K0.2%+7.8%1.470%
2/12/2025 JPMorgan Chase & Co.61,624$63K0.0%+26,011.9%0.113%
2/11/2025 Prudential Financial Inc.49,200$51K0.0%N/A0.090%
2/11/2025 Virtu Financial LLC46,046$47K0.0%N/A0.084%
2/10/2025 Monimus Capital Management LP310,908$320K0.3%N/A0.570%
2/6/2025 Atlas Venture Life Science Advisors LLC305,255$314K0.0%-24.2%0.560%
11/16/2024 Geode Capital Management LLC481,187$645K0.0%-2.2%0.891%
8/9/2024 Renaissance Technologies LLC975,952$1.27M0.0%+14.2%1.808%
8/9/2024 Atlas Venture Life Science Advisors LLC535,336$696K0.1%-11.9%0.992%
8/6/2024 Acadian Asset Management LLC1,071,860$1.39M0.0%+40.6%1.985%
5/20/2024 Virtu Financial LLC18,180$31K0.0%N/A0.034%
5/16/2024 Murchinson Ltd.873,910$1.50M0.1%+1.3%1.622%
5/14/2024 Anson Funds Management LP3,750,450$6.45M0.4%-12.7%6.959%
5/10/2024 Acadian Asset Management LLC762,598$1.31M0.0%+121.8%1.415%
5/10/2024 Vanguard Group Inc.1,653,432$2.84M0.0%+0.6%3.068%
5/6/2024 Atlas Venture Life Science Advisors LLC607,613$1.05M0.1%-40.0%1.128%
2/14/2024 ADAR1 Capital Management LLC1,067,711$1.57M0.6%N/A2.015%
11/15/2023 Rock Springs Capital Management LP57,373$69K0.0%-91.4%0.109%
11/14/2023 AWM Investment Company Inc.333,400$403K0.1%-13.0%0.632%
11/13/2023 Acadian Asset Management LLC272,024$327K0.0%+56.8%0.516%
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8/14/2023 Anson Funds Management LP3,444,862$5.00M0.8%+3.0%6.537%
8/11/2023 AWM Investment Company Inc.383,400$556K0.1%-70.5%0.729%
8/11/2023 Atlas Venture Life Science Advisors LLC1,013,438$1.47M0.2%-1.7%1.928%
8/7/2023 Acadian Asset Management LLC173,539$250K0.0%N/A0.330%
8/7/2023 Royce & Associates LP22,851$33K0.0%N/A0.043%
8/3/2023 Mackenzie Financial Corp17,198$25K0.0%N/A0.033%
7/27/2023 Virtu Financial LLC22,195$32K0.0%N/A0.042%
5/15/2023 Anson Funds Management LP3,344,862$4.85M0.8%+10.8%6.363%
4/17/2023 Bourgeon Capital Management LLC25,600$37K0.0%+95.4%0.049%
2/14/2023 AWM Investment Company Inc.1,300,400$2.25M0.3%-43.5%3.708%
11/16/2022 Alphabet Inc.889,979$1.78M0.1%N/A2.538%
11/16/2022 Anson Funds Management LP1,473,872$2.95M0.3%N/A4.203%
11/15/2022 Murchinson Ltd.762,700$1.53M0.4%N/A2.175%
11/15/2022 BVF Inc. IL1,929,376$3.86M0.2%-37.6%5.501%
10/21/2022 Weitzel Financial Services Inc.14,200$28K0.0%N/A0.040%
8/9/2022Kingsbury Capital Investment Advisors LLC60,844$45K0.1%N/A0.185%
7/27/2022 Assenagon Asset Management S.A.131,020$97K0.0%+466.6%0.399%
5/17/2022 Rock Springs Capital Management LP990,913$8.62M0.2%+4.8%3.025%
5/16/2022 Eversept Partners LP59,639$519K0.0%N/A0.182%
5/16/2022 Granahan Investment Management LLC113,322$986K0.0%-70.1%0.346%
5/11/2022 GSA Capital Partners LLP25,916$225K0.0%N/A0.079%
5/6/2022 Sentinel Pension Advisors Inc.42,000$365K0.1%+39.1%0.128%
5/5/2022 New York State Common Retirement Fund17,123$149K0.0%-68.1%0.052%
5/3/2022 Bourgeon Capital Management LLC63,096$549K0.1%+23.1%0.193%
4/25/2022 Assenagon Asset Management S.A.23,123$201K0.0%N/A0.071%
2/14/2022 Williams Jones Wealth Management LLC.75,000$1.20M0.0%-28.9%0.232%
2/10/2022 Rafferty Asset Management LLC34,958$560K0.0%+86.1%0.108%
2/9/2022 BNP Paribas Arbitrage SA8,997$144K0.0%+107.2%0.028%
2/9/2022 Dimensional Fund Advisors LP371,222$5.94M0.0%+12.6%1.148%
2/8/2022 Sentinel Pension Advisors Inc.30,200$484K0.2%+49.5%0.093%
2/8/2022 Northern Trust Corp253,200$4.05M0.0%-1.8%0.783%
2/4/2022IndexIQ Advisors LLC28,689$459K0.0%-6.1%0.089%
2/3/2022OUP Management Co. LLC249,070$3.99M1.8%N/A0.771%
2/2/2022 New York State Common Retirement Fund53,728$860K0.0%-24.6%0.166%
1/31/2022 Bourgeon Capital Management LLC51,246$820K0.2%+22.8%0.159%
1/28/2022 Allspring Global Investments Holdings LLC10,186$163K0.0%N/A0.032%
1/21/2022 Russell Investments Group Ltd.7,250$116K0.0%-11.0%0.022%
1/10/2022 Patriot Financial Group Insurance Agency LLC4,150$66K0.0%N/A0.013%
11/16/2021 BVF Inc. IL1,809,352$33.31M1.3%-15.4%5.628%
11/15/2021 Rock Springs Capital Management LP941,543$17.33M0.4%-2.5%2.929%
11/15/2021 Royal Bank of Canada180,102$3.32M0.0%+8,249.7%0.560%
11/15/2021 Granahan Investment Management Inc. MA555,614$10.23M0.2%+67.0%1.728%
11/15/2021 Dimensional Fund Advisors LP329,633$6.07M0.0%-12.0%1.025%
11/12/2021 Brandywine Global Investment Management LLC58,400$1.08M0.0%N/A0.182%
11/12/2021 The Manufacturers Life Insurance Company14,276$263K0.0%-10.4%0.044%
11/12/2021 Geode Capital Management LLC444,914$8.19M0.0%+7.5%1.384%
11/10/2021 Goldman Sachs Group Inc.137,579$2.53M0.0%+1.0%0.428%
11/10/2021IndexIQ Advisors LLC30,543$562K0.0%+11.1%0.095%
11/10/2021 Citigroup Inc.16,085$296K0.0%-59.1%0.050%
11/10/2021 Rafferty Asset Management LLC18,789$346K0.0%-21.4%0.058%
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11/10/2021 Alliancebernstein L.P.11,934$220K0.0%-16.2%0.037%
11/9/2021 Bourgeon Capital Management LLC41,746$769K0.2%N/A0.130%
11/9/2021 Barclays PLC9,965$183K0.0%+79.1%0.031%
11/9/2021BlackRock Inc.1,802,528$33.19M0.0%+1.3%5.607%
11/8/2021 Russell Investments Group Ltd.8,147$149K0.0%-53.1%0.025%
11/5/2021 Advisor Group Holdings Inc.2,548$46K0.0%-74.7%0.008%
11/2/2021 New York State Common Retirement Fund71,220$1.31M0.0%+42.8%0.222%
11/1/2021 SG Americas Securities LLC10,617$195K0.0%N/A0.033%
10/29/2021 Janney Montgomery Scott LLC26,000$479K0.0%+10.6%0.081%
10/20/2021 Sentinel Pension Advisors Inc.20,200$372K0.1%N/A0.063%
(Data available from 1/1/2016 forward)

SPRO Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of SPRO shares?

During the previous two years, 26 institutional investors and hedge funds held shares of Spero Therapeutics. The most heavily invested institutionals were Vanguard Group Inc. ($2.84M), Anson Funds Management LP ($2.74M), Murchinson Ltd. ($1.50M), Geode Capital Management LLC ($1.48M), Renaissance Technologies LLC ($1.14M), ADAR1 Capital Management LLC ($825K), and Acadian Asset Management LLC ($626K).Learn more on Spero Therapeutics' institutional investors.

What percentage of Spero Therapeutics' stock is owned by institutional investors?

25.60% of Spero Therapeutics' stock is owned by institutional investors. Learn more on SPRO's institutional investor holdings.

Which institutional investors have been buying Spero Therapeutics' stock?

Of the 20 institutional investors that purchased Spero Therapeutics' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Anson Funds Management LP ($3.89M), ADAR1 Capital Management LLC ($1.13M), Acadian Asset Management LLC ($826.49K), Monimus Capital Management LP ($310.91K), Renaissance Technologies LLC ($252.43K), Mackenzie Financial Corp ($177.13K), and Stonepine Capital Management LLC ($156.89K).

How much institutional buying is happening at Spero Therapeutics?

Institutional investors have bought a total of 5,192,560 shares in the last 24 months. This purchase volume represents approximately $4.73M in transactions.

Which of Spero Therapeutics' major shareholders have been selling company stock?

The following institutional investors have sold Spero Therapeutics stock in the last 24 months: Acadian Asset Management LLC ($168.71K), Atlas Venture Life Science Advisors LLC ($97.63K), Anson Funds Management LP ($40.95K), Bridgeway Capital Management LLC ($40K), Geode Capital Management LLC ($25.17K), and Northern Trust Corp ($25.05K).

How much institutional selling is happening at Spero Therapeutics?

Institutional investors have sold a total of 397,514 shares in the last 24 months. This volume of shares sold represents approximately $449.15K in transactions.


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This page (NASDAQ:SPRO) was last updated on 8/28/2025 by MarketBeat.com Staff
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