Free Trial
→ Here’s How to Claim Your Stake in Elon’s Private Company, xAI (From Brownstone Research) (Ad) Buy SPRO Stock  Free SPRO Stock Alerts

Spero Therapeutics (SPRO) Institutional Ownership

Spero Therapeutics logo
$0.66 -0.01 (-1.94%)
As of 04/30/2025 04:00 PM Eastern
Compare

Institutional Ownership Changes (13F Filings) for Spero Therapeutics (NASDAQ:SPRO)

Current
Institutional Ownership
Percentage
25.60%
Number of
Institutional Buyers
(last 12 months)
15
Total
Institutional Inflows
(last 12 months)
$2.45M
Number of
Institutional Sellers
(last 12 months)
4
Total
Institutional Outflows
(last 12 months)
$1.87M
Get SPRO Insider Trade Alerts

Want to know when executives and insiders are buying or selling Spero Therapeutics stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily.

Skip Chart & View Institutional Buying and Selling Data

SPRO Institutional Buying and Selling by Quarter

Spero Therapeutics Major Shareholders & Ownership History

Export to Excel
Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
2/20/2025Mackenzie Financial Corp187,559$193K0.0%+487.9%0.344%
2/17/2025Squarepoint Ops LLC55,051$57K0.0%N/A0.101%
2/17/2025Anson Funds Management LP3,839,886$3.96M0.4%+2.4%7.043%
2/14/2025Jane Street Group LLC52,869$54K0.0%N/A0.097%
2/14/2025Northern Trust Corp86,447$89K0.0%-22.5%0.159%
2/14/2025Three Seasons Wealth LLC30,000$31K0.0%N/A0.055%
2/13/2025XTX Topco Ltd30,138$31K0.0%N/A0.055%
2/13/2025Renaissance Technologies LLC1,105,591$1.14M0.0%+13.4%2.028%
2/13/2025ADAR1 Capital Management LLC801,277$825K0.2%+7.8%1.470%
2/12/2025JPMorgan Chase & Co.61,624$63K0.0%+26,011.9%0.113%
2/11/2025Prudential Financial Inc.49,200$51K0.0%N/A0.090%
2/11/2025Virtu Financial LLC46,046$47K0.0%N/A0.084%
2/10/2025Monimus Capital Management LP310,908$320K0.3%N/A0.570%
2/6/2025Atlas Venture Life Science Advisors LLC305,255$314K0.0%-24.2%0.560%
11/16/2024Geode Capital Management LLC481,187$645K0.0%-2.2%0.891%
8/9/2024Renaissance Technologies LLC975,952$1.27M0.0%+14.2%1.808%
8/9/2024Atlas Venture Life Science Advisors LLC535,336$696K0.1%-11.9%0.992%
8/6/2024Acadian Asset Management LLC1,071,860$1.39M0.0%+40.6%1.985%
5/20/2024Virtu Financial LLC18,180$31K0.0%N/A0.034%
5/16/2024Murchinson Ltd.873,910$1.50M0.1%+1.3%1.622%
5/14/2024Anson Funds Management LP3,750,450$6.45M0.4%-12.7%6.959%
5/10/2024Acadian Asset Management LLC762,598$1.31M0.0%+121.8%1.415%
5/10/2024Vanguard Group Inc.1,653,432$2.84M0.0%+0.6%3.068%
5/6/2024Atlas Venture Life Science Advisors LLC607,613$1.05M0.1%-40.0%1.128%
2/14/2024ADAR1 Capital Management LLC1,067,711$1.57M0.6%N/A2.015%
11/15/2023Rock Springs Capital Management LP57,373$69K0.0%-91.4%0.109%
11/14/2023AWM Investment Company Inc.333,400$403K0.1%-13.0%0.632%
11/13/2023Acadian Asset Management LLC272,024$327K0.0%+56.8%0.516%
8/14/2023Anson Funds Management LP3,444,862$5.00M0.8%+3.0%6.537%
8/11/2023AWM Investment Company Inc.383,400$556K0.1%-70.5%0.729%
8/11/2023Atlas Venture Life Science Advisors LLC1,013,438$1.47M0.2%-1.7%1.928%
8/7/2023Acadian Asset Management LLC173,539$250K0.0%N/A0.330%
8/7/2023Royce & Associates LP22,851$33K0.0%N/A0.043%
8/3/2023Mackenzie Financial Corp17,198$25K0.0%N/A0.033%
7/27/2023Virtu Financial LLC22,195$32K0.0%N/A0.042%
5/15/2023Anson Funds Management LP3,344,862$4.85M0.8%+10.8%6.363%
4/17/2023 Bourgeon Capital Management LLC25,600$37K0.0%+95.4%0.049%
2/14/2023AWM Investment Company Inc.1,300,400$2.25M0.3%-43.5%3.708%
11/16/2022Alphabet Inc.889,979$1.78M0.1%N/A2.538%
11/16/2022Anson Funds Management LP1,473,872$2.95M0.3%N/A4.203%
Here’s How to Claim Your Stake in Elon’s Private Company, xAI (Ad)

I predict this single breakthrough could make Elon the world’s first trillionaire — and mint more new millionaires than any tech advance in history. And for a limited time, you have the chance to claim a stake in this project, even though it’s housed inside Elon’s private company, xAI.

All the details are waiting for you now — but you need to act before the May 1st funding window clos
11/15/2022Murchinson Ltd.762,700$1.53M0.4%N/A2.175%
11/15/2022BVF Inc. IL1,929,376$3.86M0.2%-37.6%5.501%
10/21/2022Weitzel Financial Services Inc.14,200$28K0.0%N/A0.040%
8/9/2022Kingsbury Capital Investment Advisors LLC60,844$45K0.1%N/A0.185%
7/27/2022 Assenagon Asset Management S.A.131,020$97K0.0%+466.6%0.399%
5/17/2022Rock Springs Capital Management LP990,913$8.62M0.2%+4.8%3.025%
5/16/2022Eversept Partners LP59,639$519K0.0%N/A0.182%
5/16/2022Granahan Investment Management LLC113,322$986K0.0%-70.1%0.346%
5/11/2022GSA Capital Partners LLP25,916$225K0.0%N/A0.079%
5/6/2022 Sentinel Pension Advisors Inc.42,000$365K0.1%+39.1%0.128%
5/5/2022New York State Common Retirement Fund17,123$149K0.0%-68.1%0.052%
5/3/2022 Bourgeon Capital Management LLC63,096$549K0.1%+23.1%0.193%
4/25/2022 Assenagon Asset Management S.A.23,123$201K0.0%N/A0.071%
2/14/2022Williams Jones Wealth Management LLC.75,000$1.20M0.0%-28.9%0.232%
2/10/2022Rafferty Asset Management LLC34,958$560K0.0%+86.1%0.108%
2/9/2022BNP Paribas Arbitrage SA8,997$144K0.0%+107.2%0.028%
2/9/2022Dimensional Fund Advisors LP371,222$5.94M0.0%+12.6%1.148%
2/8/2022 Sentinel Pension Advisors Inc.30,200$484K0.2%+49.5%0.093%
2/8/2022Northern Trust Corp253,200$4.05M0.0%-1.8%0.783%
2/4/2022IndexIQ Advisors LLC28,689$459K0.0%-6.1%0.089%
2/3/2022OUP Management Co. LLC249,070$3.99M1.8%N/A0.771%
2/2/2022New York State Common Retirement Fund53,728$860K0.0%-24.6%0.166%
1/31/2022 Bourgeon Capital Management LLC51,246$820K0.2%+22.8%0.159%
1/28/2022 Allspring Global Investments Holdings LLC10,186$163K0.0%N/A0.032%
1/21/2022Russell Investments Group Ltd.7,250$116K0.0%-11.0%0.022%
1/10/2022 Patriot Financial Group Insurance Agency LLC4,150$66K0.0%N/A0.013%
11/16/2021BVF Inc. IL1,809,352$33.31M1.3%-15.4%5.628%
11/15/2021Rock Springs Capital Management LP941,543$17.33M0.4%-2.5%2.929%
11/15/2021Royal Bank of Canada180,102$3.32M0.0%+8,249.7%0.560%
11/15/2021Granahan Investment Management Inc. MA555,614$10.23M0.2%+67.0%1.728%
11/15/2021Dimensional Fund Advisors LP329,633$6.07M0.0%-12.0%1.025%
11/12/2021Brandywine Global Investment Management LLC58,400$1.08M0.0%N/A0.182%
11/12/2021The Manufacturers Life Insurance Company14,276$263K0.0%-10.4%0.044%
11/12/2021Geode Capital Management LLC444,914$8.19M0.0%+7.5%1.384%
11/10/2021Goldman Sachs Group Inc.137,579$2.53M0.0%+1.0%0.428%
11/10/2021IndexIQ Advisors LLC30,543$562K0.0%+11.1%0.095%
11/10/2021Citigroup Inc.16,085$296K0.0%-59.1%0.050%
11/10/2021Rafferty Asset Management LLC18,789$346K0.0%-21.4%0.058%
11/10/2021Alliancebernstein L.P.11,934$220K0.0%-16.2%0.037%
11/9/2021 Bourgeon Capital Management LLC41,746$769K0.2%N/A0.130%
11/9/2021Barclays PLC9,965$183K0.0%+79.1%0.031%
11/9/2021BlackRock Inc.1,802,528$33.19M0.0%+1.3%5.607%
11/8/2021Russell Investments Group Ltd.8,147$149K0.0%-53.1%0.025%
11/5/2021Advisor Group Holdings Inc.2,548$46K0.0%-74.7%0.008%
11/2/2021New York State Common Retirement Fund71,220$1.31M0.0%+42.8%0.222%
11/1/2021 SG Americas Securities LLC10,617$195K0.0%N/A0.033%
10/29/2021 Janney Montgomery Scott LLC26,000$479K0.0%+10.6%0.081%
10/20/2021 Sentinel Pension Advisors Inc.20,200$372K0.1%N/A0.063%
9/3/2021Parametric Portfolio Associates LLC29,947$418K0.0%-4.7%0.093%
8/17/2021Metropolitan Life Insurance Co NY6,987$98K0.0%+139,640.0%0.022%
The Man I Turn to In Times Like This (Ad)

A storm is brewing in the markets: new tariffs, recession warnings, and panic in the headlines. That’s when publisher Brett Aitken turns to Whitney Tilson—a man CNBC once dubbed “The Prophet.” Tilson just released a new prediction that runs counter to what mainstream finance is telling you.

Market chaos? Hear Tilson’s take now
8/17/2021MetLife Investment Management LLC9,977$139K0.0%+392.0%0.031%
8/16/2021California State Teachers Retirement System33,446$467K0.0%+8.2%0.104%
8/16/2021Charles Schwab Investment Management Inc.60,496$845K0.0%+13.4%0.188%
8/16/2021State Street Corp810,738$11.32M0.0%-40.2%2.522%
8/16/2021Goldman Sachs Group Inc.136,262$1.90M0.0%-46.7%0.424%
8/13/2021Northern Trust Corp260,886$3.64M0.0%+8.9%0.812%
8/13/2021Liberty Wealth Management LLC27,920$2M0.1%+1,296.0%0.087%
8/13/2021Geode Capital Management LLC413,761$5.78M0.0%+13.8%1.287%
8/13/2021Vanguard Group Inc.1,276,790$17.82M0.0%+15.4%3.972%
8/13/2021ProShare Advisors LLC11,608$162K0.0%N/A0.036%
(Data available from 1/1/2016 forward)

SPRO Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of SPRO shares?

During the previous two years, 21 institutional investors and hedge funds held shares of Spero Therapeutics. The most heavily invested institutionals were Anson Funds Management LP ($3.96M), Vanguard Group Inc. ($2.84M), Murchinson Ltd. ($1.50M), Acadian Asset Management LLC ($1.39M), Renaissance Technologies LLC ($1.14M), ADAR1 Capital Management LLC ($825K), and Geode Capital Management LLC ($645K).Learn more on SPRO's institutional investors.

What percentage of Spero Therapeutics stock is owned by institutional investors?

25.60% of Spero Therapeutics stock is owned by institutional investors. Learn more on SPRO's institutional investor holdings.

Which institutional investors have been buying Spero Therapeutics stock?

Of the 16 institutional investors that purchased Spero Therapeutics stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: ADAR1 Capital Management LLC ($1.13M), Acadian Asset Management LLC ($1.00M), Anson Funds Management LP ($514.69K), Monimus Capital Management LP ($310.91K), Renaissance Technologies LLC ($252.43K), Mackenzie Financial Corp ($172.85K), and Virtu Financial LLC ($86.42K).

How much institutional buying is happening at Spero Therapeutics?

Institutional investors have bought a total of 3,785,242 shares in the last 24 months. This purchase volume represents approximately $5.10M in transactions.

Which Spero Therapeutics major shareholders have been selling company stock?

The following institutional investors have sold Spero Therapeutics stock in the last 24 months: AWM Investment Company Inc. ($967K), Rock Springs Capital Management LP ($612.16K), Atlas Venture Life Science Advisors LLC ($593.45K), Anson Funds Management LP ($547.25K), Northern Trust Corp ($25.05K), and Geode Capital Management LLC ($11K).

How much institutional selling is happening at Spero Therapeutics?

Institutional investors have sold a total of 2,755,913 shares in the last 24 months. This volume of shares sold represents approximately $4.03M in transactions.


Related Companies

This page (NASDAQ:SPRO) was last updated on 5/1/2025 by MarketBeat.com Staff
From Our Partners
How to invest in Elon Musk’s Optimus before its launch
Elon Musk is set to completely take over the AI industry with Optimus… A breakthrough AI-powered robot that El...
InvestorPlace | Sponsored
Is he more powerful than Trump?
Is there anybody more powerful than Donald Trump right now? In a single tariff announcement, he wiped out n...
Porter & Company | Sponsored
Trump and Buffett Are Quietly Leading America’s Gold Revival
The “Buffett Indicator” Predicts Gold Set To Dominate for Next Decade Each time the Buffett Indicator has...
Golden Portfolio | Sponsored
This isn’t a trade war. It’s worse…
Investigative Journalist Bombhsell: The Curse on the U.S Dollar Depleted retirement accounts? Meme coin inv...
Stansberry Research | Sponsored
Elon Musk’s next move from the Oval Office?
No one is closer to President Trump than Tesla CEO Elon Musk. He's been dubbed Trump's "first buddy." Tr...
Weiss Ratings | Sponsored
Elon Set to Shock the World by May 1st ?
Tech legend Jeff Brown recently traveled to the industrial zone of South Memphis to investigate what he believ...
Brownstone Research | Sponsored
They rigged the game
The U.S. fired the first shot with 145% tariffs. Apple relies heavily on Chinese production. Tesla needs Ch...
Investors Alley | Sponsored
Trump Treasure April 19
Thanks to President Trump… A $900 investment across5 specific cryptos… Could gain 12,000% so quickly tha...
Paradigm Press | Sponsored