Spero Therapeutics (SPRO) News Today $2.83 -0.06 (-2.08%) Closing price 06/13/2025 04:00 PM EasternExtended Trading$2.82 -0.01 (-0.35%) As of 06/13/2025 07:48 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Headlines Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock SPRO Latest News All Sources Trusted Sources MarketBeat Benzinga Bloomberg GlobeNewswire GuruFocus MarketWatch Motley Fool NASDAQ PR Newswire Reuters Seeking Alpha TalkMarkets The Street TipRanks The Wall Street Journal Wall Street Zen Yahoo Finance Source Sentiment refers to the positivity or negativity of each headline according to our language processing algorithm. Sentiment All Sentiments Very Positive Positive Neutral Negative Very Negative Most Recent June 2025 May 2025 April 2025 March 2025 February 2025 January 2025 December 2024 November 2024 October 2024 September 2024 August 2024 July 2024 June 2024 May 2024 April 2024 March 2024 February 2024 January 2024 December 2023 November 2023 October 2023 September 2023 August 2023 July 2023 June 2023 May 2023 April 2023 March 2023 February 2023 January 2023 December 2022 November 2022 October 2022 September 2022 August 2022 July 2022 Time Period Spero Therapeutics, Inc. (NASDAQ:SPRO) Short Interest Up 446.6% in MaySpero Therapeutics, Inc. (NASDAQ:SPRO - Get Free Report) was the recipient of a large increase in short interest in May. As of May 31st, there was short interest totalling 3,480,000 shares, an increase of 446.6% from the May 15th total of 636,700 shares. Based on an average daily volume of 3,760,000 shares, the short-interest ratio is presently 0.9 days. Currently, 6.7% of the shares of the stock are sold short.June 11 at 7:31 PM | marketbeat.comSpero Therapeutics -- Additional Upside Potential Following Positive Phase 3 ResultsJune 11 at 3:50 PM | seekingalpha.comSpero Therapeutics, Inc. (NASDAQ:SPRO) Stake Boosted by Mackenzie Financial CorpMackenzie Financial Corp lifted its stake in Spero Therapeutics, Inc. (NASDAQ:SPRO - Free Report) by 487.9% during the fourth quarter, according to its most recent disclosure with the Securities and Exchange Commission. The fund owned 187,559 shares of the company's stock after acquiring an additioJune 6, 2025 | marketbeat.comWhy Spero Therapeutics, Inc. (SPRO) Surged Last WeekMay 31, 2025 | msn.comBest Penny Stocks To Watch Today - May 28thSpero Therapeutics, BigBear.ai, and LiveWire Group are the three Penny stocks to watch today, according to MarketBeat's stock screener tool. Penny stocks are shares of small, thinly traded companies that typically trade for less than $5 per share, often on over-the-counter markets or smaller exchanMay 30, 2025 | marketbeat.comSpero Therapeutics Jumps as Oral Carbapenem Hits Phase 3 MilestoneMay 30, 2025 | msn.comSpero Therapeutics Sees Unusually Large Options Volume (NASDAQ:SPRO)Spero Therapeutics, Inc. (NASDAQ:SPRO - Get Free Report) was the recipient of unusually large options trading on Wednesday. Investors purchased 1,962 call options on the stock. This is an increase of approximately 3,988% compared to the typical volume of 48 call options.May 29, 2025 | marketbeat.comSpero Therapeutics Shares Soar as Trial with GSK Ends Early on EfficacyMay 28, 2025 | marketwatch.comSpero Therapeutics Stock Skyrockets on Strong Phase 3 Trial ResultsMay 28, 2025 | msn.comSpero Therapeutics and GSK Announce PIVOT-PO Phase 3 Study for Tebipenem HBr Stopped Early for Efficacy Following Review by Independent Data Monitoring CommitteeMay 28, 2025 | globenewswire.comSpero Therapeutics Announces First Quarter 2025 Operating Results and Provides a Business UpdateMay 13, 2025 | globenewswire.comSpero Therapeutics to Report First Quarter 2025 Financial Results and Provide Business Update on Tuesday, May 13, 2025May 5, 2025 | globenewswire.comSpero Therapeutics, Inc.: Spero Therapeutics Appoints Esther Rajavelu as President and Chief Executive OfficerApril 29, 2025 | finanznachrichten.deSpero Therapeutics Appoints Esther Rajavelu as President and Chief Executive OfficerApril 28, 2025 | globenewswire.comSpero Therapeutics Analyst RatingsApril 7, 2025 | benzinga.comTD Cowen Sticks to Their Hold Rating for Spero Therapeutics (SPRO)April 2, 2025 | markets.businessinsider.comWe're Keeping An Eye On Spero Therapeutics' (NASDAQ:SPRO) Cash Burn RateMarch 29, 2025 | finance.yahoo.comSpero Therapeutics reports Q4 EPS (38c), consensus (31c)March 28, 2025 | markets.businessinsider.comSpero Therapeutics, Inc.: Spero Therapeutics Announces Fourth Quarter and Full Year 2024 Operating Results and Provides a Business UpdateMarch 28, 2025 | finanznachrichten.deSpero Therapeutics, Inc. (SPRO) Q4 2024 Earnings Call TranscriptMarch 27, 2025 | seekingalpha.comSpero Therapeutics Announces Fourth Quarter and Full Year 2024 Operating Results and Provides a Business UpdateMarch 27, 2025 | globenewswire.com1SPRO : A Glimpse of Spero Therapeutics's Earnings PotentialMarch 26, 2025 | benzinga.comSpero Therapeutics to Report Fourth Quarter and Full Year 2024 Financial Results and Provide Business Update on Thursday, March 27, 2025March 18, 2025 | globenewswire.comUPDATE – Spero Therapeutics to Present at TD Cowen 45th Annual Health Care ConferenceFebruary 25, 2025 | globenewswire.comSpero Therapeutics to Present at TD Cowen 45th Annual Health Care ConferenceFebruary 25, 2025 | globenewswire.comSpero Therapeutics CEO sells shares worth $121,159February 6, 2025 | msn.comSpero Therapeutics, Inc. (NASDAQ:SPRO) CFO Esther Rajavelu Sells 20,689 SharesFebruary 6, 2025 | insidertrades.comSpero therapeutics CFO sells $16,137 in stockFebruary 6, 2025 | msn.comSpero Therapeutics COO Timothy Keutzer sells shares for $44,097February 6, 2025 | msn.comOptimistic Buy Rating for Spero Therapeutics Amid Strategic Initiatives and PartnershipsJanuary 30, 2025 | markets.businessinsider.comSpero Therapeutics Inc SPROJanuary 16, 2025 | morningstar.comSpero Therapeutics, Inc.: Spero Therapeutics Provides Business Update and Announces Interim Leadership ChangesJanuary 10, 2025 | finanznachrichten.deSpero Therapeutics announces interim leadership changesJanuary 10, 2025 | markets.businessinsider.comSpero Therapeutics Makes Interim Changes To Management After Wells Notice From SECJanuary 10, 2025 | markets.businessinsider.comSpero Therapeutics names Esther Rajavelu as Interim President and CEOJanuary 10, 2025 | msn.comSpero Therapeutics Provides Business Update and Announces Interim Leadership ChangesJanuary 10, 2025 | globenewswire.comSpero Therapeutics (NASDAQ:SPRO) Stock Passes Below Two Hundred Day Moving Average - Time to Sell?Spero Therapeutics (NASDAQ:SPRO) Stock Price Crosses Below 200-Day Moving Average - What's Next?December 28, 2024 | marketbeat.comSpero Therapeutics (SPRO) was downgraded to a Hold Rating at Evercore ISIDecember 23, 2024 | markets.businessinsider.comSpero Therapeutics downgraded at Evercore on lack of capital allocation clarityDecember 20, 2024 | markets.businessinsider.comEvercore ISI Group Downgrades Spero Therapeutics (SPRO)December 20, 2024 | msn.comWhat 4 Analyst Ratings Have To Say About Spero TherapeuticsDecember 20, 2024 | benzinga.comEvercore ISI Downgrades Spero Therapeutics (NASDAQ:SPRO) to In-LineEvercore ISI downgraded Spero Therapeutics from an "outperform" rating to an "in-line" rating and set a $5.00 target price on the stock. in a research report on Friday.December 20, 2024 | marketbeat.comSpero Therapeutics (NASDAQ:SPRO) Stock Crosses Below Two Hundred Day Moving Average - Should You Sell?Spero Therapeutics (NASDAQ:SPRO) Share Price Passes Below 200-Day Moving Average - What's Next?December 13, 2024 | marketbeat.comHC Wainwright Issues Pessimistic Estimate for SPRO EarningsSpero Therapeutics, Inc. (NASDAQ:SPRO - Free Report) - Research analysts at HC Wainwright lowered their FY2024 earnings estimates for Spero Therapeutics in a report released on Monday, December 2nd. HC Wainwright analyst R. Selvaraju now forecasts that the company will post earnings per share ofDecember 4, 2024 | marketbeat.comBuy Rating Reiterated for Spero Therapeutics Amid Promising Trial Progress and Strategic PartnershipDecember 3, 2024 | markets.businessinsider.comTD Cowen Downgrades Spero Therapeutics (SPRO)November 19, 2024 | msn.comSpero Therapeutics downgraded to Hold from Buy at TD CowenNovember 18, 2024 | markets.businessinsider.comSpero Therapeutics (NASDAQ:SPRO) Receives Hold Rating from TD CowenTD Cowen restated a "hold" rating on shares of Spero Therapeutics in a research note on Monday.November 18, 2024 | marketbeat.comTD Cowen downgrades Spero Therapeutics (SPRO) to a HoldNovember 18, 2024 | markets.businessinsider.comSpero Therapeutics: Strategic Shift and Earnings UpdateNovember 16, 2024 | markets.businessinsider.com Get Spero Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for SPRO and its competitors with MarketBeat's FREE daily newsletter. Email Address SPRO Media Mentions By Week SPRO Media Sentiment Learn about the media sentiment score. Each headline receives a score ranging from 2 (good news) to -2 (bad news). Our company news sentiment scores track the average news sentiment of articles about each company over the most recent 7 days in order to identify companies that are receiving positive press. SPRO News Sentiment▼0.980.88▲Average Medical News Sentiment SPRO News Coverage Learn about the media coverage comparison. We track news headlines from hundreds of news outlets and tag them by company. This chart compares the number of articles about this company in the last seven days compared with the average number of articles about this company on a typical week. SPRO Articles This Week▼41▲SPRO Articles Average Week Get Spero Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for SPRO and its competitors with MarketBeat's FREE daily newsletter. Email Address Related Companies and Tools Related Companies Phathom Pharmaceuticals News ChromaDex News Stoke Therapeutics News Upstream Bio News Taysha Gene Therapies News Bicycle Therapeutics News Mind Medicine (MindMed) News Dianthus Therapeutics News Kura Oncology News Maravai LifeSciences News Headlines Tools Trending Media MentionsHigh Media Sentiment StocksLive News FeedMarketBeat OriginalsStock Ideas This page (NASDAQ:SPRO) was last updated on 6/14/2025 by MarketBeat.com Staff From Our PartnersThe Trump Dump is starting; Get out of stocks now?The first 365 days of the Trump presidency… Will be the best time to get rich in American history.Paradigm Press | SponsoredCollect $7k per month from Tesla’s SECRET dividendI just uncovered a strategy that could pay out up to $7,013 every month—without needing a traditional dividend...Investors Alley | SponsoredSilicon Valley Gold RushA new technology has sparked a modern-day gold rush in Silicon Valley. 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