Sarepta Therapeutics (SRPT) Stock Price, News & Analysis

Company Overview

Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, gene therapies, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 injection to treat duchenne muscular dystrophy (duchenne) in patients with confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; VYONDYS 53 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping; AMONDYS 45 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene; and ELEVIDYS, an adeno-associated virus based gene therapy for the treatment of ambulatory pediatric patients aged 4 through 5 years with duchenne with a confirmed mutation in the duchenne gene. The company is also developing SRP-5051, a peptide conjugated PMO that binds exon 51 of dystrophin pre-mRNA; and SRP-9003, a limb-girdle muscular dystrophies gene therapy program. It has collaboration and license agreements with F. Hoffman-La Roche Ltd; Nationwide Children's Hospital; Genevant Sciences; University of Florida; Dyno Therapeutics; Hansa Biopharma; Duke University; Genethon; and StrideBio. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.

Key Stats

• Today's Range: $18.52 to $20.12
• 50-Day Range: $11.93 to $36.18
• 52-Week Range: $10.41 to $144.22
• Volume: 16.66 million shs
• Average Volume: 17.44 million shs
• Market Capitalization: $1.96 billion
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $43.50
• Consensus Rating: Hold

Sarepta Therapeutics Stock Analysis - MarketRank™

Sarepta Therapeutics scored higher than 92% of companies evaluated by MarketBeat, and ranked 92nd out of 937 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 4.0 / 5
• Analyst Rating: Hold

Consensus Rating

Sarepta Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.07, and is based on 8 buy ratings, 15 hold ratings, and 6 sell ratings.

Amount of Analyst Coverage

Sarepta Therapeutics has been the subject of 27 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

Earnings and Valuation

• Score: 1.9 / 5
• Proj. Earnings Growth: 309.74%

Earnings Growth

Earnings for Sarepta Therapeutics are expected to grow by 309.74% in the coming year, from $2.67 to $10.94 per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Sarepta Therapeutics is -23.06, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Sarepta Therapeutics is -23.06, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Sarepta Therapeutics has a P/B Ratio of 1.44. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

23.20% of the float of Sarepta Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Sarepta Therapeutics has a short interest ratio ("days to cover") of 1.8, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Sarepta Therapeutics has recently increased by 40.98%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Sarepta Therapeutics does not currently pay a dividend.

Dividend Growth

Sarepta Therapeutics does not have a long track record of dividend growth.

Sustainability and ESG

• Score: 4.2 / 5
• Environmental Score: -1.65

Percentage of Shares Shorted

23.20% of the float of Sarepta Therapeutics has been sold short.

Short Interest Ratio / Days to Cover

Sarepta Therapeutics has a short interest ratio ("days to cover") of 1.8, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Sarepta Therapeutics has recently increased by 40.98%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 2.4 / 5
• News Sentiment: 0.25

News Sentiment

Sarepta Therapeutics has a news sentiment score of 0.25. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.54 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 66 news articles for Sarepta Therapeutics this week, compared to 78 articles on an average week.

Search Interest

106 people have searched for SRPT on MarketBeat in the last 30 days. This is an increase of 15% compared to the previous 30 days.

MarketBeat Follows

27 people have added Sarepta Therapeutics to their MarketBeat watchlist in the last 30 days. This is an increase of 108% compared to the previous 30 days.

Company Ownership

• Score: 1.7 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Sarepta Therapeutics insiders have not sold or bought any company stock.

Percentage Held by Insiders

Only 7.60% of the stock of Sarepta Therapeutics is held by insiders.

Percentage Held by Institutions

86.68% of the stock of Sarepta Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

SRPT Stock Analysis - Frequently Asked Questions

How have SRPT shares performed this year?

Sarepta Therapeutics' stock was trading at $121.59 at the beginning of 2025. Since then, SRPT shares have decreased by 83.5% and is now trading at $20.06.

How were Sarepta Therapeutics' earnings last quarter?

Sarepta Therapeutics, Inc. (NASDAQ:SRPT) released its quarterly earnings data on Wednesday, August, 6th. The biotechnology company reported $2.02 EPS for the quarter, topping the consensus estimate of $0.89 by $1.13. The company's revenue was up 68.4% on a year-over-year basis.

Does Sarepta Therapeutics have any subsidiaries?

Sarepta Therapeutics subsidiaries include these companies: Myonexus Therapeutics, Eisai, Sarepta Securities Corp., Sarepta Therapeutics Three LLC, and ST International Holdings Two Inc..

Who are Sarepta Therapeutics' major shareholders?

Sarepta Therapeutics' top institutional investors include Geode Capital Management LLC (1.91%), Federated Hermes Inc. (1.34%), Aberdeen Group plc (1.26%) and Norges Bank (0.93%). Insiders that own company stock include Douglas S Ingram, Michael Andrew Chambers, Richard Barry, Ian Michael Estepan, Claude Nicaise, Hans Lennart Rudolf Wigzell, Bilal Arif, Dallan Murray, Ryan Edward Brown, Stephen Mayo and Kathryn Jean Boor.
View institutional ownership trends.

How do I buy shares of Sarepta Therapeutics?

Shares of SRPT stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Sarepta Therapeutics own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Sarepta Therapeutics investors own include Zomedica (ZOM), NVIDIA (NVDA), Humana (HUM), American Water Works (AWK), Meta Platforms (META), Voyager Therapeutics (VYGR) and Waste Connections (WCN).

Company Calendar

• Last Earnings: 8/06/2025
• Today: 8/22/2025
• Next Earnings (Estimated): 11/05/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:SRPT
• Previous Symbol: NASDAQ:AVII
• CIK: 873303
• Web: www.sareptatherapeutics.com
• Phone: (617) 274-4000
• Fax: 425-354-5038
• Employees: 1,372
• Year Founded: 1980

Price Target and Rating

• Average Price Target for Sarepta Therapeutics: $43.50
• High Price Target: $150.00
• Low Price Target: $12.00
• Potential Upside/Downside: +116.8%
• Consensus Rating: Hold
• Rating Score (0-4): 2.07
• Research Coverage: 29 Analysts

Profitability

• EPS (Trailing Twelve Months): ($0.87)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: 7.51
• P/E Growth: N/A
• Net Income: $235.24 million
• Net Margins: -2.34%
• Pretax Margin: -0.97%
• Return on Equity: -1.03%
• Return on Assets: -0.37%

Debt

• Debt-to-Equity Ratio: 0.84
• Current Ratio: 2.89
• Quick Ratio: 1.81

Sales & Book Value

• Annual Sales: $1.90 billion
• Price / Sales: 1.03
• Cash Flow: $2.37 per share
• Price / Cash Flow: 8.45
• Book Value: $13.89 per share
• Price / Book: 1.44

Miscellaneous

• Outstanding Shares: 97,710,000
• Free Float: 90,287,000
• Market Cap: $1.96 billion
• Optionable: Optionable
• Beta: 0.46