NASDAQ:SYBX Synlogic (SYBX) Stock Price, News & Analysis $1.12 -0.02 (-1.75%) As of 12:08 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsInsider TradesOwnershipSEC Filings About Synlogic Stock (NASDAQ:SYBX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Synlogic alerts:Sign Up Key Stats Today's Range$1.12▼$1.1350-Day Range$0.67▼$1.2352-Week Range$0.54▼$1.87Volume1,070 shsAverage Volume67,987 shsMarket Capitalization$13.72 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingSell Company Overview Synlogic, Inc. is a biotechnology company focused on developing medicines based on synthetic biology. Its platform engineers probiotic bacteria, primarily strains of Escherichia coli, to perform specific therapeutic functions inside the gastrointestinal tract, such as consuming disease-associated metabolites or producing beneficial compounds. The company’s development programs have targeted rare metabolic disorders. Notable candidates have included SYNB1618 and SYNB1934 for phenylketonuria, a condition involving impaired processing of phenylalanine, and SYNB8802 for hyperoxaluria, a disorder characterized by excessive oxalate production. Synlogic has also investigated its technology in other metabolic diseases and therapeutic areas. Founded in 2013 and headquartered in Cambridge, Massachusetts, Synlogic advanced its programs through clinical development with an initial focus on the United States and potential applications in international markets. The company’s research has centered on using engineered living medicines to address conditions that may be difficult to treat with conventional pharmaceutical approaches.AI Generated. May Contain Errors. Read More Synlogic Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks1st Percentile Overall ScoreSYBX MarketRank™: Synlogic scored higher than 1% of companies evaluated by MarketBeat, and ranked 903rd out of 908 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion0.5 / 5Analyst RatingSell Consensus RatingSynlogic has received a consensus rating of Sell. The company's average rating score is 1.00, and is based on no strong buy ratings, no buy ratings, no hold ratings, and 1 sell rating.Amount of Analyst CoverageSynlogic has received no research coverage in the past 90 days.Read more about Synlogic's stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Synlogic are expected to grow in the coming year, from ($2.71) to ($0.47) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Synlogic is -4.31, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Synlogic is -4.31, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioSynlogic has a P/B Ratio of 1.03. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.Read more about Synlogic's valuation and earnings. Short InterestN/AShort Interest LevelN/A Short InterestThere is no current short interest data available for SYBX. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldSynlogic does not currently pay a dividend.Dividend GrowthSynlogic does not have a long track record of dividend growth. News and Social Media0.0 / 5News SentimentN/A News Coverage This WeekMarketBeat has tracked 1 news article for Synlogic this week, compared to 0 articles on an average week. Company Ownership0.8 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Synlogic insiders have not sold or bought any company stock.Percentage Held by Insiders2.62% of the stock of Synlogic is held by insiders.Percentage Held by Institutions63.40% of the stock of Synlogic is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Synlogic's insider trading history. Receive SYBX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Synlogic and its competitors with MarketBeat's FREE daily newsletter. 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SYBX Stock News HeadlinesSynlogic (NASDAQ:SYBX) and Inovio Pharmaceuticals (NASDAQ:INO) Head to Head ContrastSeptember 21, 2026 | americanbankingnews.comBRODSKY & SMITH SHAREHOLDER UPDATE: Notifying Investors of the Following Investigations: Varex Imaging Corporation (Nasdaq – VREX), Synlogic, Inc. (OTC – SYBX), Bowman Consulting Group Ltd. (Nasdaq – BWMN), Nathan's Famous, Inc. (Nasdaq – NATH)August 28, 2026 | globenewswire.comMy top 3 AI picks for the next decadeAlexander Green bought Apple in 1996, recommended Nvidia at a split-adjusted 66 cents in 2004, and picked up Amazon and Netflix under $3 per share in 2005. Now the chief investment strategist at The Oxford Club has identified three AI stocks he believes could be the most profitable investments of the next decade.September 25 at 1:00 AM | The Oxford Club (Ad)SYBX Stock Alert: Halper Sadeh LLC is Investigating Whether Synlogic, Inc. is Obtaining a Fair Price for its ShareholdersAugust 10, 2026 | tmcnet.comSynlogic and Caldera Therapeutics announce merger and $278 million private placementJuly 29, 2026 | msn.comSynlogic Challenges Nasdaq Delisting NoticeNovember 26, 2025 | tipranks.comWe Think Synlogic (NASDAQ:SYBX) Can Afford To Drive Business GrowthSeptember 18, 2025 | uk.finance.yahoo.comSynlogic, Inc. (SYBX) Latest Stock News & Headlines - Yahoo FinanceJune 28, 2025 | finance.yahoo.comSee More Headlines SYBX Stock Analysis - Frequently Asked Questions How have SYBX shares performed this year? Synlogic's stock was trading at $1.12 at the beginning of the year. Since then, SYBX stock has increased by 0.0% and is now trading at $1.12. How were Synlogic's earnings last quarter? Synlogic, Inc. (NASDAQ:SYBX) announced its quarterly earnings results on Thursday, November, 13th. The biotechnology company reported ($0.19) earnings per share for the quarter, missing the consensus estimate of ($0.11) by $0.08. When did Synlogic's stock split? Synlogic's stock reverse split before market open on Thursday, September 28th 2023.The 1-15 reverse split was announced on Thursday, September 28th 2023. The number of shares owned by shareholders was adjusted after the market closes on Thursday, September 28th 2023. An investor that had 100 shares of stock prior to the reverse split would have 7 shares after the split. When did Synlogic IPO? Synlogic (SYBX) raised $88 million in an initial public offering (IPO) on Wednesday, September 30th 2015. The company issued 6,250,000 shares at $13.00-$15.00 per share. How do I buy shares of Synlogic? Shares of SYBX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Synlogic own? Based on aggregate information from My MarketBeat watchlists, some other companies that Synlogic investors own include Sangamo Therapeutics (SGMO), Precision Drilling (PDS), First Financial Bankshares (FFIN), Sorrento Therapeutics (SRNE) and Exelixis (EXEL). Company Calendar Last Earnings11/13/2025Today9/25/2026Next Earnings (Estimated)11/11/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (8m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 SYBX's financial health is in the Yellow zone, according to TradeSmith. SYBX has been in this zone for over 8 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:SYBX CIK1527599 Webwww.synlogictx.com Phone(617) 401-9975Fax512-681-5201Employees80Year Founded2013Profitability EPS (Trailing Twelve Months)($0.06) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$23.36 million Net MarginsN/A Pretax MarginN/A Return on Equity-26.47% Return on Assets-18.00% Debt Debt-to-Equity RatioN/A Current Ratio2.65 Quick Ratio2.65 Sales & Book Value Annual Sales$8 thousand Price / Sales1,714.86 Cash FlowN/A Price / Cash FlowN/A Book Value$1.09 per share Price / Book1.03Miscellaneous Outstanding Shares12,249,000Free Float11,392,000Market Cap$13.72 million OptionableNo Data Beta0.50 Social Links 7 Stocks to Buy Before the Robotics RevolutionRobotics and automation are rapidly becoming essential infrastructure across healthcare, manufacturing, logistics, and many other industries. "Physical AI" is coming. Learn which seven companies are most positioned to benefit as intelligent robots enter the workforce.Get This Free Report This page (NASDAQ:SYBX) was last updated on 9/25/2026 by MarketBeat.com Staff. 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