NASDAQ:SYBX Synlogic (SYBX) Stock Price, News & Analysis $1.20 0.00 (0.00%) As of 08/21/2026 11:40 AM Eastern Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsInsider TradesOwnershipSEC Filings About Synlogic Stock (NASDAQ:SYBX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Synlogic alerts:Sign Up Key Stats Today's Range$1.15▼$1.2250-Day Range$0.67▼$1.2352-Week Range$0.54▼$1.87Volume30,870 shsAverage Volume75,794 shsMarket Capitalization$14.70 millionP/E RatioN/ADividend YieldN/APrice TargetN/AConsensus RatingSell Company Overview Synlogic, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of synthetic biotics to treat metabolic diseases in the United States. Its pipeline include SYNB1618, an orally administered, non-systemically absorbed drug candidate to treat phenylketonuria; SYNB1934, an orally administered, non-systemically absorbed drug candidate, which is in Phase III clinical trial to treat phenylketonuria; SYNB1353, an orally administered, non-systemically absorbed drug candidate, which is in Phase I clinical to treat homocystinuria; SYNB8802, an orally administered, non-systemically absorbed drug candidate that is in Phase II clinical trial for the treatment of enteric hyperoxaluria; and SYNB2081 to lower uric acid for the potential treatment of gout. The company has a collaboration agreement with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc. for the research and pre-clinical development of a synthetic biotic medicine for the treatment of inflammatory bowel disease; and Ginkgo Bioworks, Inc. Synlogic, Inc. is based in Cambridge, Massachusetts. Read More Synlogic Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks6th Percentile Overall ScoreSYBX MarketRank™: Synlogic scored higher than 6% of companies evaluated by MarketBeat, and ranked 889th out of 915 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion0.5 / 5Analyst RatingSell Consensus RatingSynlogic has received a consensus rating of Sell. The company's average rating score is 1.00, and is based on no strong buy ratings, no buy ratings, no hold ratings, and 1 sell rating.Amount of Analyst CoverageSynlogic has received no research coverage in the past 90 days.Read more about Synlogic's stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Synlogic are expected to grow in the coming year, from ($2.71) to ($0.47) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Synlogic is -4.62, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Synlogic is -4.62, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioSynlogic has a P/B Ratio of 1.10. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.Read more about Synlogic's valuation and earnings. Short InterestN/AShort Interest LevelN/A Short InterestThere is no current short interest data available for SYBX. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldSynlogic does not currently pay a dividend.Dividend GrowthSynlogic does not have a long track record of dividend growth. News and Social Media2.9 / 5News SentimentN/A News SentimentSynlogic has a news sentiment score of 0.67. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Healthcare companies.News Coverage This WeekMarketBeat has tracked 1 news article for Synlogic this week, compared to 0 articles on an average week.Search Interest1 people have searched for SYBX on MarketBeat in the last 30 days. Company Ownership0.8 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Synlogic insiders have not sold or bought any company stock.Percentage Held by Insiders2.62% of the stock of Synlogic is held by insiders.Percentage Held by Institutions63.40% of the stock of Synlogic is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Synlogic's insider trading history. Receive SYBX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Synlogic and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. 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SYBX Stock News HeadlinesSynlogic (NASDAQ:SYBX) Shares Cross Above 50 Day Moving Average - Here's WhyAugust 18, 2026 | americanbankingnews.comSYBX Stock Alert: Halper Sadeh LLC is Investigating Whether Synlogic, Inc. is Obtaining a Fair Price for its ShareholdersAugust 10, 2026 | tmcnet.comBank of America grew this stake 139%Bank of America raised its stake in a small gold company by 139%. Jane Street increased its position by 159%, and Millennium by 122%. Kopernik Global made it their largest holding, owning roughly 8% of the company. It holds rights to an 88 million ounce deposit with existing roads, power, and permits that never expire. Market cap sits near $4 billion against a deposit worth hundreds of billions at current gold prices. | Behind the Markets (Ad)Synlogic and Caldera Therapeutics announce merger and $278 million private placementJuly 29, 2026 | msn.comSynlogic Challenges Nasdaq Delisting NoticeNovember 26, 2025 | tipranks.comWe Think Synlogic (NASDAQ:SYBX) Can Afford To Drive Business GrowthSeptember 18, 2025 | uk.finance.yahoo.comSynlogic, Inc. (SYBX) Latest Stock News & Headlines - Yahoo FinanceJune 28, 2025 | finance.yahoo.comSynlogic's executive sells shares worth $2,802February 5, 2025 | msn.comSee More Headlines SYBX Stock Analysis - Frequently Asked Questions How have SYBX shares performed this year? Synlogic's stock was trading at $1.12 at the start of the year. Since then, SYBX shares have increased by 7.1% and is now trading at $1.20. How were Synlogic's earnings last quarter? Synlogic, Inc. (NASDAQ:SYBX) released its quarterly earnings data on Thursday, November, 13th. The biotechnology company reported ($0.19) earnings per share for the quarter, missing the consensus estimate of ($0.11) by $0.08. When did Synlogic's stock split? Synlogic's stock reverse split on the morning of Thursday, September 28th 2023.The 1-15 reverse split was announced on Thursday, September 28th 2023. The number of shares owned by shareholders was adjusted after the closing bell on Thursday, September 28th 2023. An investor that had 100 shares of stock prior to the reverse split would have 7 shares after the split. When did Synlogic IPO? Synlogic (SYBX) raised $88 million in an initial public offering (IPO) on Wednesday, September 30th 2015. The company issued 6,250,000 shares at $13.00-$15.00 per share. How do I buy shares of Synlogic? Shares of SYBX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Synlogic own? Based on aggregate information from My MarketBeat watchlists, some other companies that Synlogic investors own include Sangamo Therapeutics (SGMO), Precision Drilling (PDS), First Financial Bankshares (FFIN), Sorrento Therapeutics (SRNE) and Exelixis (EXEL). Company Calendar Last Earnings11/13/2025Today8/23/2026Next Earnings (Estimated)11/11/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Yellow Zone (7m+) 1-Year History Aug 25 Nov 25 Feb 26 May 26 Aug 26 SYBX's financial health is in the Yellow zone, according to TradeSmith. SYBX has been in this zone for over 7 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:SYBX CIK1527599 Webwww.synlogictx.com Phone(617) 401-9975Fax512-681-5201Employees80Year Founded2013Profitability EPS (Trailing Twelve Months)($0.06) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$23.36 million Net MarginsN/A Pretax MarginN/A Return on Equity-26.47% Return on Assets-18.00% Debt Debt-to-Equity RatioN/A Current Ratio2.65 Quick Ratio2.65 Sales & Book Value Annual Sales$8 thousand Price / Sales1,837.35 Cash FlowN/A Price / Cash FlowN/A Book Value$1.09 per share Price / Book1.10Miscellaneous Outstanding Shares12,249,000Free Float11,392,000Market Cap$14.70 million OptionableNo Data Beta0.48 Social Links The 10 Best High-Yield Dividend Stocks for 2026Discover the 10 Best High-Yield Dividend Stocks for 2026 and secure reliable income in uncertain markets. 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