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Synlogic (SYBX) Competitors

Synlogic logo
$0.66 0.00 (-0.02%)
As of 05/19/2026 12:42 PM Eastern

SYBX vs. LSTA, SKYE, LTRN, PLRZ, and HOWL

Should you buy Synlogic stock or one of its competitors? MarketBeat compares Synlogic with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Synlogic include Lisata Therapeutics (LSTA), Skye Bioscience (SKYE), Lantern Pharma (LTRN), Polyrizon (PLRZ), and Werewolf Therapeutics (HOWL). These companies are all part of the "pharmaceutical products" industry.

How does Synlogic compare to Lisata Therapeutics?

Synlogic (NASDAQ:SYBX) and Lisata Therapeutics (NASDAQ:LSTA) are both small-cap medical companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, analyst recommendations, media sentiment, risk, profitability, earnings, valuation and dividends.

Synlogic's return on equity of -26.47% beat Lisata Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
SynlogicN/A -26.47% -18.00%
Lisata Therapeutics N/A -103.54%-83.08%

Lisata Therapeutics has a consensus price target of $15.00, indicating a potential upside of 380.77%. Given Lisata Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Lisata Therapeutics is more favorable than Synlogic.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Synlogic
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Lisata Therapeutics
1 Sell rating(s)
2 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.67

Synlogic has a beta of 0.52, indicating that its stock price is 48% less volatile than the broader market. Comparatively, Lisata Therapeutics has a beta of 0.81, indicating that its stock price is 19% less volatile than the broader market.

In the previous week, Lisata Therapeutics had 3 more articles in the media than Synlogic. MarketBeat recorded 3 mentions for Lisata Therapeutics and 0 mentions for Synlogic. Synlogic's average media sentiment score of 0.00 beat Lisata Therapeutics' score of -0.30 indicating that Synlogic is being referred to more favorably in the media.

Company Overall Sentiment
Synlogic Neutral
Lisata Therapeutics Neutral

63.4% of Synlogic shares are owned by institutional investors. Comparatively, 8.9% of Lisata Therapeutics shares are owned by institutional investors. 2.6% of Synlogic shares are owned by company insiders. Comparatively, 9.1% of Lisata Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Lisata Therapeutics has higher revenue and earnings than Synlogic. Synlogic is trading at a lower price-to-earnings ratio than Lisata Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Synlogic$8K965.02-$23.36M-$0.06N/A
Lisata Therapeutics$170K167.20-$16.59M-$1.86N/A

Summary

Lisata Therapeutics beats Synlogic on 8 of the 14 factors compared between the two stocks.

How does Synlogic compare to Skye Bioscience?

Synlogic (NASDAQ:SYBX) and Skye Bioscience (NASDAQ:SKYE) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their earnings, institutional ownership, risk, analyst recommendations, media sentiment, profitability, valuation and dividends.

Skye Bioscience has a consensus target price of $9.80, indicating a potential upside of 1,251.35%. Given Skye Bioscience's stronger consensus rating and higher probable upside, analysts plainly believe Skye Bioscience is more favorable than Synlogic.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Synlogic
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Skye Bioscience
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.57

Synlogic's return on equity of -26.47% beat Skye Bioscience's return on equity.

Company Net Margins Return on Equity Return on Assets
SynlogicN/A -26.47% -18.00%
Skye Bioscience N/A -217.27%-162.39%

Synlogic has a beta of 0.52, suggesting that its share price is 48% less volatile than the broader market. Comparatively, Skye Bioscience has a beta of 3.03, suggesting that its share price is 203% more volatile than the broader market.

In the previous week, Skye Bioscience had 3 more articles in the media than Synlogic. MarketBeat recorded 3 mentions for Skye Bioscience and 0 mentions for Synlogic. Skye Bioscience's average media sentiment score of 0.26 beat Synlogic's score of 0.00 indicating that Skye Bioscience is being referred to more favorably in the news media.

Company Overall Sentiment
Synlogic Neutral
Skye Bioscience Neutral

63.4% of Synlogic shares are held by institutional investors. Comparatively, 21.1% of Skye Bioscience shares are held by institutional investors. 2.6% of Synlogic shares are held by insiders. Comparatively, 6.2% of Skye Bioscience shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Synlogic has higher revenue and earnings than Skye Bioscience. Synlogic is trading at a lower price-to-earnings ratio than Skye Bioscience, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Synlogic$8K965.02-$23.36M-$0.06N/A
Skye BioscienceN/AN/A-$55.92M-$1.44N/A

Summary

Skye Bioscience beats Synlogic on 9 of the 15 factors compared between the two stocks.

How does Synlogic compare to Lantern Pharma?

Lantern Pharma (NASDAQ:LTRN) and Synlogic (NASDAQ:SYBX) are both small-cap medical companies, but which is the superior investment? We will compare the two companies based on the strength of their dividends, profitability, analyst recommendations, institutional ownership, earnings, risk, media sentiment and valuation.

Synlogic's return on equity of -26.47% beat Lantern Pharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Lantern PharmaN/A -198.34% -129.08%
Synlogic N/A -26.47%-18.00%

In the previous week, Lantern Pharma had 8 more articles in the media than Synlogic. MarketBeat recorded 8 mentions for Lantern Pharma and 0 mentions for Synlogic. Lantern Pharma's average media sentiment score of 1.11 beat Synlogic's score of 0.00 indicating that Lantern Pharma is being referred to more favorably in the media.

Company Overall Sentiment
Lantern Pharma Positive
Synlogic Neutral

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lantern Pharma
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Synlogic
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Lantern Pharma has higher earnings, but lower revenue than Synlogic. Synlogic is trading at a lower price-to-earnings ratio than Lantern Pharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lantern PharmaN/AN/A-$17.12M-$1.45N/A
Synlogic$8K965.02-$23.36M-$0.06N/A

Lantern Pharma has a beta of 2.1, meaning that its stock price is 110% more volatile than the broader market. Comparatively, Synlogic has a beta of 0.52, meaning that its stock price is 48% less volatile than the broader market.

28.6% of Lantern Pharma shares are owned by institutional investors. Comparatively, 63.4% of Synlogic shares are owned by institutional investors. 8.5% of Lantern Pharma shares are owned by insiders. Comparatively, 2.6% of Synlogic shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Summary

Lantern Pharma beats Synlogic on 6 of the 11 factors compared between the two stocks.

How does Synlogic compare to Polyrizon?

Polyrizon (NASDAQ:PLRZ) and Synlogic (NASDAQ:SYBX) are both small-cap medical companies, but which is the better stock? We will compare the two businesses based on the strength of their risk, dividends, institutional ownership, earnings, valuation, media sentiment, profitability and analyst recommendations.

63.4% of Synlogic shares are held by institutional investors. 2.6% of Synlogic shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Polyrizon's return on equity of 0.00% beat Synlogic's return on equity.

Company Net Margins Return on Equity Return on Assets
PolyrizonN/A N/A N/A
Synlogic N/A -26.47%-18.00%

In the previous week, Polyrizon had 4 more articles in the media than Synlogic. MarketBeat recorded 4 mentions for Polyrizon and 0 mentions for Synlogic. Polyrizon's average media sentiment score of 1.03 beat Synlogic's score of 0.00 indicating that Polyrizon is being referred to more favorably in the media.

Company Overall Sentiment
Polyrizon Positive
Synlogic Neutral

Polyrizon has a beta of -2.04, suggesting that its stock price is 304% less volatile than the broader market. Comparatively, Synlogic has a beta of 0.52, suggesting that its stock price is 48% less volatile than the broader market.

Polyrizon has higher earnings, but lower revenue than Synlogic.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
PolyrizonN/AN/A-$3.34MN/AN/A
Synlogic$8K965.02-$23.36M-$0.06N/A

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Polyrizon
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Synlogic
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Summary

Polyrizon beats Synlogic on 5 of the 9 factors compared between the two stocks.

How does Synlogic compare to Werewolf Therapeutics?

Werewolf Therapeutics (NASDAQ:HOWL) and Synlogic (NASDAQ:SYBX) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their analyst recommendations, media sentiment, earnings, dividends, risk, institutional ownership, profitability and valuation.

In the previous week, Werewolf Therapeutics had 2 more articles in the media than Synlogic. MarketBeat recorded 2 mentions for Werewolf Therapeutics and 0 mentions for Synlogic. Synlogic's average media sentiment score of 0.00 beat Werewolf Therapeutics' score of -1.10 indicating that Synlogic is being referred to more favorably in the news media.

Company Overall Sentiment
Werewolf Therapeutics Negative
Synlogic Neutral

Werewolf Therapeutics presently has a consensus price target of $3.75, indicating a potential upside of 775.35%. Given Werewolf Therapeutics' stronger consensus rating and higher probable upside, equities research analysts plainly believe Werewolf Therapeutics is more favorable than Synlogic.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Werewolf Therapeutics
1 Sell rating(s)
4 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.14
Synlogic
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Synlogic has lower revenue, but higher earnings than Werewolf Therapeutics. Synlogic is trading at a lower price-to-earnings ratio than Werewolf Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Werewolf Therapeutics$1.88M11.07-$60.82M-$1.24N/A
Synlogic$8K965.02-$23.36M-$0.06N/A

Werewolf Therapeutics has a beta of 0.41, indicating that its stock price is 59% less volatile than the broader market. Comparatively, Synlogic has a beta of 0.52, indicating that its stock price is 48% less volatile than the broader market.

64.8% of Werewolf Therapeutics shares are owned by institutional investors. Comparatively, 63.4% of Synlogic shares are owned by institutional investors. 23.6% of Werewolf Therapeutics shares are owned by insiders. Comparatively, 2.6% of Synlogic shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Synlogic's return on equity of -26.47% beat Werewolf Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Werewolf TherapeuticsN/A -208.23% -75.12%
Synlogic N/A -26.47%-18.00%

Summary

Werewolf Therapeutics beats Synlogic on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SYBX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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SYBX vs. The Competition

MetricSynlogicMED IndustryMedical SectorNASDAQ Exchange
Market Cap$7.72M$3.25B$6.24B$12.23B
Dividend YieldN/A2.34%2.80%5.32%
P/E Ratio-2.5418.5220.7825.05
Price / Sales965.02270.32531.2172.66
Price / CashN/A124.5843.0954.25
Price / Book0.616.609.816.83
Net Income-$23.36M$24.18M$3.55B$335.69M
7 Day Performance3.11%-3.74%-2.11%-2.15%
1 Month Performance3.99%-7.95%-4.14%-2.47%
1 Year Performance-41.60%50.32%28.35%27.13%

Synlogic Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
SYBX
Synlogic
N/A$0.66
0.0%
N/A-40.0%$7.72M$8KN/A80
LSTA
Lisata Therapeutics
1.6251 of 5 stars
$3.28
+0.6%
$15.00
+357.3%
+18.6%$29.87M$170KN/A30
SKYE
Skye Bioscience
2.2781 of 5 stars
$0.82
+0.8%
$9.80
+1,095.6%
-66.3%$28.79MN/AN/A11
LTRN
Lantern Pharma
0.8996 of 5 stars
$2.51
+21.8%
N/A-13.9%$28.39MN/AN/A20
PLRZ
Polyrizon
1.1001 of 5 stars
$15.18
+1.1%
N/A+41.2%$28.39MN/AN/AN/A

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This page (NASDAQ:SYBX) was last updated on 5/20/2026 by MarketBeat.com Staff.
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