Tiziana Life Sciences (TLSA) Short Interest Ratio & Short Volume $2.04 -0.09 (-4.23%) Closing price 04:00 PM EasternExtended Trading$1.96 -0.09 (-4.17%) As of 04:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsFDA EventsHeadlinesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Tiziana Life Sciences Short Interest DataTiziana Life Sciences (TLSA) has a short interest of 1.11 million shares, representing 1.76% of the float (the number of shares available for trading by the public). This marks a 40.17% increase in short interest from the previous month. The short interest ratio (days to cover) is 3.0, indicating that it would take 3.0 days of the average trading volume of 568,340 shares to cover all short positions.Current Short Interest1,110,000 sharesPrevious Short Interest791,900 sharesChange Vs. Previous Month+40.17%Dollar Volume Sold Short$1.89 millionShort Interest Ratio3.0 Days to CoverLast Record DateSeptember 15, 2025Outstanding Shares116,848,000 sharesFloat Size63,120,000 sharesShort Percent of Float1.76%Today's Trading Volume609,875 sharesAverage Trading Volume568,340 sharesToday's Volume Vs. Average107% Short Selling Tiziana Life Sciences? Sign up to receive the latest short interest report for Tiziana Life Sciences and its competitors with MarketBeat's FREE newsletter. 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Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartTLSA Short Interest Over TimeTLSA Days to Cover Over TimeTLSA Percentage of Float Shorted Over Time Tiziana Life Sciences Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 9/15/20251,110,000 shares $1.89 million +40.2%1.8%3 $1.70 8/31/2025791,900 shares $1.43 million +20.5%1.3%2.3 $1.81 8/15/2025657,200 shares $1.29 million +12.7%1.0%1.9 $1.97 7/31/2025583,000 shares $1.46 million +14.0%0.9%1.7 $2.50 7/15/2025511,600 shares $752.05 thousand +8.0%0.8%1.6 $1.47 6/30/2025473,600 shares $748.29 thousand -20.6%0.8%1.4 $1.58 6/15/2025596,500 shares $924.58 thousand -16.7%1.0%1.7 $1.55 5/31/2025715,900 shares $952.15 thousand -21.3%1.0%1.7 $1.33 5/15/2025909,100 shares $1.26 million -5.0%1.3%1.3 $1.39 4/30/2025957,000 shares $1.30 million -8.9%1.3%1.3 $1.36 Get the Latest News and Ratings for TLSA and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Tiziana Life Sciences and its competitors with MarketBeat's FREE daily newsletter. 4/15/20251,050,000 shares $850.50 thousand +39.5%1.5%1.2 $0.81 3/31/2025752,500 shares $812.70 thousand -6.9%1.1%0.8 $1.08 3/15/2025808,600 shares $1.27 million +42.5%1.1%0.8 $1.57 2/28/2025567,600 shares $732.20 thousand -39.3%0.8%0.6 $1.29 2/15/2025934,300 shares $739.97 thousand -23.4%1.3%1.4 $0.79 1/31/20251,220,000 shares $835.70 thousand +128.0%1.7%2 $0.69 1/15/2025535,000 shares $421.37 thousand -21.4%0.8%0.8 $0.79 12/31/2024680,800 shares $473.97 thousand +300.2%1.0%2 $0.70 12/15/2024170,100 shares $160.08 thousand -18.3%0.2%0.6 $0.94 11/30/2024208,100 shares $197.70 thousand -24.3%0.3%0.8 $0.95 11/15/2024274,900 shares $244.80 thousand +13.6%0.4%1.1 $0.89 10/31/2024241,900 shares $235.85 thousand +350.5%0.4%0.9 $0.98 10/15/202453,700 shares $49.40 thousand -11.4%N/A0.2 $0.92 9/30/202460,600 shares $58.18 thousand +44.6%N/A0.2 $0.96 9/15/202441,900 shares $38.75 thousand -67.0%N/A0.2 $0.92 8/31/2024127,100 shares $127.10 thousand -53.7%N/A0.5 $1.00 8/15/2024274,700 shares $324.15 thousand +175.3%N/A1 $1.18 7/31/202499,800 shares $106.79 thousand +39.4%N/A0.4 $1.07 7/15/202471,600 shares $57.65 thousand -44.3%N/A0.3 $0.81 6/30/2024128,600 shares $118.18 thousand +38.4%N/A0.5 $0.92 6/15/202492,900 shares $68.75 thousand -48.6%N/A0.4 $0.74 5/31/2024180,700 shares $180.68 thousand +6.4%N/A0.8 $1.00 5/15/2024169,800 shares $107.82 thousand -56.9%N/A0.9 $0.64 4/30/2024394,100 shares $255.22 thousand +52.9%N/A2.2 $0.65 4/15/2024257,800 shares $128.87 thousand -20.0%N/A1.7 $0.50 3/31/2024322,200 shares $146.28 thousand -11.9%N/A4.7 $0.45 3/15/2024365,800 shares $181.07 thousand +20.9%N/A5.3 $0.50 2/29/2024302,700 shares $145.48 thousand -1.3%N/A4.6 $0.48 2/15/2024306,700 shares $163.32 thousand +4.6%N/A6.9 $0.53 1/31/2024293,200 shares $155.69 thousand -26.7%N/A5.5 $0.53 1/15/2024399,800 shares $228.09 thousand -11.8%N/A6.6 $0.57 12/31/2023453,200 shares $253.79 thousand -17.2%N/A4.6 $0.56 12/15/2023547,300 shares $311.52 thousand +3.4%N/A5.7 $0.57 11/30/2023529,300 shares $312.29 thousand -4.7%N/A5.2 $0.59 11/15/2023555,200 shares $308.14 thousand -16.8%N/A4.9 $0.56 10/31/2023667,500 shares $433.88 thousand +13.7%N/A1 $0.65 10/15/2023587,100 shares $469.68 thousand -1.0%N/A0.9 $0.80 9/30/2023592,900 shares $391.25 thousand -11.1%N/A1 $0.66 9/15/2023666,900 shares $460.69 thousand -14.9%N/A1.1 $0.69 8/31/2023783,700 shares $569.75 thousand +420.0%N/A1.3 $0.73 8/15/2023150,700 shares $123.95 thousand +53.2%N/A0.2 $0.82 7/31/202398,400 shares $63.96 thousand -10.1%N/A0.8 $0.65 7/15/2023109,500 shares $74.58 thousand +8.7%N/A0.8 $0.68 6/30/2023100,700 shares $68.62 thousand -51.5%N/A0.5 $0.68 6/15/2023207,400 shares $161.75 thousand +139.2%N/A1 $0.78 5/31/202386,700 shares $73.70 thousand +14.2%N/A0.4 $0.85 5/15/202375,900 shares $59.97 thousand +94.6%N/A0.5 $0.79 4/30/202339,000 shares $30.62 thousand -62.6%N/A0.3 $0.79 4/15/2023104,300 shares $111.60 thousand -27.1%N/A0.7 $1.07 3/31/2023143,100 shares $156.21 thousand +213.1%N/A1.7 $1.09 3/15/202345,700 shares $25.88 thousand +6.0%N/A0.8 $0.57 2/28/202343,100 shares $24.01 thousand +39.9%N/A0.9 $0.56 2/15/202330,800 shares $17.72 thousand -19.8%N/A0.6 $0.58 1/31/202338,400 shares $24.77 thousand -41.3%N/A0.7 $0.65 1/15/202365,400 shares $43.81 thousand +15.6%N/A1.2 $0.67 12/30/202256,600 shares $33.88 thousand -23.1%N/A1.1 $0.60 12/15/202273,600 shares $42.32 thousand +3.7%N/A1.5 $0.58 11/30/202271,000 shares $46.74 thousand -13.9%N/A1.3 $0.66 11/15/202282,500 shares $54.50 thousand +3.3%N/A1.5 $0.66 10/31/202279,900 shares $55.53 thousand +4.9%N/A1.4 $0.70 10/15/202276,200 shares $56.08 thousand -24.4%N/A1.5 $0.74 9/30/2022100,800 shares $78.62 thousand +95.4%N/A1.9 $0.78 9/15/202251,600 shares $42.82 thousand +174.5%N/A0.9 $0.83 8/31/202218,800 shares $14.34 thousand +27.9%N/A0.4 $0.76 8/15/202214,700 shares $11.03 thousand -5.2%N/A0.2 $0.75 7/31/202215,500 shares $11.33 thousand +36.0%N/A0.2 $0.73 7/15/202211,400 shares $8.44 thousand -39.0%N/A0.1 $0.74 6/30/202218,700 shares $13.94 thousand -7.4%N/A0.2 $0.75 6/15/202220,200 shares $16.56 thousand -60.2%N/A0.2 $0.82 5/31/202250,700 shares $33.72 thousand -25.3%N/A0.2 $0.67 5/15/202267,900 shares $53.13 thousand -67.3%N/A0.3 $0.78 4/30/2022207,600 shares $211.75 thousand +38.0%N/A0.8 $1.02 4/15/2022150,400 shares $142.86 thousand -64.9%N/A0.6 $0.95 3/31/2022427,900 shares $449.30 thousand -41.1%N/A1.6 $1.05 3/15/2022726,700 shares $708.24 thousand +565.5%N/A2.6 $0.97 2/28/2022109,200 shares $70.99 thousand +89.3%N/A0.8 $0.65 2/15/202257,700 shares $40.39 thousand -20.3%N/A0.5 $0.70 1/31/202272,400 shares $60.09 thousand -34.1%N/A0.5 $0.83 1/15/2022109,800 shares $91.13 thousand +62.0%N/A0.8 $0.83 12/31/202167,800 shares $65.09 thousand -64.0%N/A0.5 $0.96 12/15/2021188,200 shares $207.02 thousand +6.8%N/A1.5 $1.10 11/30/2021176,300 shares $222.14 thousand -18.2%N/A1.3 $1.26 11/15/2021215,500 shares $306.01 thousand -25.4%N/A0.5 $1.42 10/29/2021289,000 shares $450.84 thousand +14.6%N/A0.6 $1.56 10/15/2021252,100 shares $380.67 thousand +57.7%N/A0.5 $1.51 9/30/2021159,900 shares $233.45 thousand -15.8%N/A0.3 $1.46 9/15/2021189,800 shares $326.46 thousand +22.1%N/A0.3 $1.72 8/31/2021155,500 shares $258.13 thousand -25.6%N/A0.2 $1.66 8/13/2021208,900 shares $359.31 thousand -29.4%N/A0.5 $1.72 7/30/2021295,700 shares $629.84 thousand +0.3%N/A0.7 $2.13 7/15/2021294,700 shares $583.51 thousand +13.2%N/A0.8 $1.98 6/30/2021260,400 shares $611.94 thousand +310.7%N/A0.6 $2.35 6/15/202163,400 shares $162.30 thousand -40.2%N/A0.1 $2.56 5/28/2021106,000 shares $249.10 thousand -28.3%N/A0.3 $2.35 5/14/2021147,800 shares $310.38 thousand +16.5%N/A0.4 $2.10 4/30/2021126,900 shares $332.48 thousand +74.1%N/A0.3 $2.62 4/15/202172,900 shares $187.35 thousand +51.6%N/A0.1 $2.57 3/31/202148,100 shares $135.64 thousand +114.7%N/A0 $2.82 3/15/202122,400 shares $68.32 thousand +15.5%N/A0 $3.05 2/26/202119,400 shares $57.81 thousand -90.9%N/A0 $2.98 2/12/2021213,600 shares $826.63 thousand -3.7%N/A0.2 $3.87 1/29/2021221,700 shares $864.63 thousand -38.2%N/A0.2 $3.90 1/15/2021358,900 shares $1.16 million -12.6%N/A0.4 $3.23 12/31/2020410,700 shares $915.86 thousand +24.3%N/A1 $2.23 12/15/2020330,400 shares $654.19 thousand -26.8%N/A0.9 $1.98 11/30/2020451,400 shares $1.17 million -8.1%N/A1.5 $2.60 11/15/2020490,900 shares $1.46 million -8.3%N/A1.7 $2.98 10/30/2020535,300 shares $2.17 million -27.9%N/A1.5 $4.05 10/15/2020741,900 shares $3.27 million +18.6%N/A0.8 $4.41 TLSA Short Interest - Frequently Asked Questions What is Tiziana Life Sciences' current short interest? Short interest is the volume of Tiziana Life Sciences shares that have been sold short but have not yet been covered or closed out. As of September 15th, investors have sold 1,110,000 shares of TLSA short. 1.76% of Tiziana Life Sciences' shares are currently sold short. Learn More on Tiziana Life Sciences' current short interest. What is a good short interest ratio for Tiziana Life Sciences? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. TLSA shares currently have a short interest ratio of 3.0. Learn More on Tiziana Life Sciences's short interest ratio. Which institutional investors are shorting Tiziana Life Sciences? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Tiziana Life Sciences: Simplex Trading LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. What is a good short interest percentage for Tiziana Life Sciences? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 1.76% of Tiziana Life Sciences' floating shares are currently sold short. Is Tiziana Life Sciences' short interest increasing or decreasing? Tiziana Life Sciences saw a increase in short interest during the month of September. As of September 15th, there was short interest totaling 1,110,000 shares, an increase of 40.2% from the previous total of 791,900 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. What is Tiziana Life Sciences' float size? Tiziana Life Sciences currently has issued a total of 116,848,000 shares. Some of Tiziana Life Sciences' outstanding shares are available for trading, while others are subject to various restrictions. The public float, also referred to as floating shares or "the float", are shares that publicly owned, unrestricted and available to trade on the open market. Tiziana Life Sciences currently has a public float of 63,120,000 shares. How does Tiziana Life Sciences' short interest compare to its competitors? 1.76% of Tiziana Life Sciences' shares are currently sold short. Here is how the short interest of companies in the industry of "pharmaceutical products" compare to Tiziana Life Sciences: Tango Therapeutics, Inc. (40.39%), Pharming Group N.V. Sponsored ADR (0.02%), Immatics N.V. (2.95%), Upstream Bio, Inc. (15.13%), Relay Therapeutics, Inc. (13.05%), Taysha Gene Therapies, Inc. (15.89%), CorMedix Inc (21.36%), Urogen Pharma (17.16%), Rezolute, Inc. (8.46%), Arbutus Biopharma Corporation (5.82%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: AppLovin Corporation ($8.81 billion), Canadian Natural Resources Limited ($5.82 billion), Reddit Inc. ($5.19 billion), Coinbase Global, Inc. ($4.52 billion), Robinhood Markets, Inc. ($4.30 billion), Charter Communications, Inc. ($3.75 billion), CoreWeave Inc. ($3.66 billion), Seagate Technology Holdings PLC ($3.57 billion), Live Nation Entertainment, Inc. ($3.33 billion), and Rocket Lab Corporation ($3.26 billion). View all of the most shorted stocks. What does it mean to sell short Tiziana Life Sciences stock? Short selling TLSA is an investing strategy that aims to generate trading profit from Tiziana Life Sciences as its price is falling. TLSA shares are trading down $0.13 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Tiziana Life Sciences? A short squeeze for Tiziana Life Sciences occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of TLSA, which in turn drives the price of the stock up even further. How often is Tiziana Life Sciences' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including TLSA, twice per month. The most recent reporting period available is September, 15 2025. More Short Interest Resources from MarketBeat Related Companies TNGX Short Interest PHAR Short Interest IMTX Short Interest UPB Short Interest RLAY Short Interest TSHA Short Interest CRMD Short Interest URGN Short Interest RZLT Short Interest ABUS Short Interest Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:TLSA) was last updated on 10/10/2025 by MarketBeat.com Staff From Our PartnersBitcoin grabs headlines, but smart money likes this tokenIf you're a futures trader (or want to be one), this could be the biggest shift you'll ever see in the prop fi...Neuro Street Trading Academy | SponsoredThe best AI stock you aren’t watching (but Elon is)Elon Musk's AI empire is already being built... not in the spotlight, but in the background. 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