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Viridian Therapeutics (VRDN) Competitors

Viridian Therapeutics logo
$24.29 -0.21 (-0.86%)
As of 08/21/2026 04:00 PM Eastern

VRDN vs. KRYS, NUVL, IONS, CYTK, and SYRE

Should you buy Viridian Therapeutics stock or one of its competitors? Viridian Therapeutics's main competitors and comparable companies include Krystal Biotech (KRYS), Nuvalent (NUVL), Ionis Pharmaceuticals (IONS), Cytokinetics (CYTK), and Spyre Therapeutics (SYRE). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Viridian Therapeutics compare to Krystal Biotech?

Viridian Therapeutics (NASDAQ:VRDN) and Krystal Biotech (NASDAQ:KRYS) are both healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their dividends, valuation, institutional ownership, analyst recommendations, earnings, risk, profitability and media sentiment.

Viridian Therapeutics has a beta of 0.91, indicating that its share price is 9% less volatile than the broader market. Comparatively, Krystal Biotech has a beta of 0.53, indicating that its share price is 47% less volatile than the broader market.

Viridian Therapeutics currently has a consensus target price of $38.93, indicating a potential upside of 60.27%. Krystal Biotech has a consensus target price of $365.40, indicating a potential upside of 5.43%. Given Viridian Therapeutics' higher possible upside, research analysts plainly believe Viridian Therapeutics is more favorable than Krystal Biotech.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Viridian Therapeutics
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.86
Krystal Biotech
0 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.92

Krystal Biotech has a net margin of 54.82% compared to Viridian Therapeutics' net margin of -505.86%. Krystal Biotech's return on equity of 19.34% beat Viridian Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Viridian Therapeutics-505.86% -72.97% -42.80%
Krystal Biotech 54.82%19.34%17.65%

86.3% of Krystal Biotech shares are owned by institutional investors. 2.4% of Viridian Therapeutics shares are owned by insiders. Comparatively, 13.1% of Krystal Biotech shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

In the previous week, Viridian Therapeutics had 3 more articles in the media than Krystal Biotech. MarketBeat recorded 10 mentions for Viridian Therapeutics and 7 mentions for Krystal Biotech. Krystal Biotech's average media sentiment score of 1.30 beat Viridian Therapeutics' score of 1.04 indicating that Krystal Biotech is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Viridian Therapeutics
8 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Krystal Biotech
5 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Krystal Biotech has higher revenue and earnings than Viridian Therapeutics. Viridian Therapeutics is trading at a lower price-to-earnings ratio than Krystal Biotech, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Viridian Therapeutics$70.85M38.84-$342.60M-$3.37N/A
Krystal Biotech$389.13M26.36$204.83M$7.9843.43

Summary

Krystal Biotech beats Viridian Therapeutics on 12 of the 17 factors compared between the two stocks.

How does Viridian Therapeutics compare to Nuvalent?

Viridian Therapeutics (NASDAQ:VRDN) and Nuvalent (NASDAQ:NUVL) are both mid-cap healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their institutional ownership, valuation, risk, media sentiment, profitability, dividends, earnings and analyst recommendations.

Viridian Therapeutics has higher revenue and earnings than Nuvalent. Nuvalent is trading at a lower price-to-earnings ratio than Viridian Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Viridian Therapeutics$70.85M38.84-$342.60M-$3.37N/A
NuvalentN/AN/A-$425.38M-$6.06N/A

Viridian Therapeutics has a beta of 0.91, meaning that its share price is 9% less volatile than the broader market. Comparatively, Nuvalent has a beta of 1.14, meaning that its share price is 14% more volatile than the broader market.

Nuvalent has a net margin of 0.00% compared to Viridian Therapeutics' net margin of -505.86%. Nuvalent's return on equity of -40.11% beat Viridian Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Viridian Therapeutics-505.86% -72.97% -42.80%
Nuvalent N/A -40.11%-35.43%

Viridian Therapeutics currently has a consensus target price of $38.93, suggesting a potential upside of 60.27%. Nuvalent has a consensus target price of $127.73, suggesting a potential upside of 3.04%. Given Viridian Therapeutics' stronger consensus rating and higher possible upside, equities analysts plainly believe Viridian Therapeutics is more favorable than Nuvalent.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Viridian Therapeutics
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.86
Nuvalent
1 Sell rating(s)
15 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.15

In the previous week, Viridian Therapeutics had 10 more articles in the media than Nuvalent. MarketBeat recorded 10 mentions for Viridian Therapeutics and 0 mentions for Nuvalent. Viridian Therapeutics' average media sentiment score of 1.04 beat Nuvalent's score of 0.00 indicating that Viridian Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Viridian Therapeutics Positive
Nuvalent Neutral

97.3% of Nuvalent shares are owned by institutional investors. 2.4% of Viridian Therapeutics shares are owned by insiders. Comparatively, 5.0% of Nuvalent shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Summary

Viridian Therapeutics beats Nuvalent on 9 of the 15 factors compared between the two stocks.

How does Viridian Therapeutics compare to Ionis Pharmaceuticals?

Viridian Therapeutics (NASDAQ:VRDN) and Ionis Pharmaceuticals (NASDAQ:IONS) are both mid-cap healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their risk, analyst recommendations, earnings, valuation, profitability, dividends, media sentiment and institutional ownership.

93.9% of Ionis Pharmaceuticals shares are owned by institutional investors. 2.4% of Viridian Therapeutics shares are owned by company insiders. Comparatively, 1.8% of Ionis Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Viridian Therapeutics has higher earnings, but lower revenue than Ionis Pharmaceuticals. Ionis Pharmaceuticals is trading at a lower price-to-earnings ratio than Viridian Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Viridian Therapeutics$70.85M38.84-$342.60M-$3.37N/A
Ionis Pharmaceuticals$944M10.52-$381.39M-$3.46N/A

Viridian Therapeutics currently has a consensus target price of $38.93, indicating a potential upside of 60.27%. Ionis Pharmaceuticals has a consensus target price of $94.15, indicating a potential upside of 57.60%. Given Viridian Therapeutics' stronger consensus rating and higher possible upside, equities research analysts clearly believe Viridian Therapeutics is more favorable than Ionis Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Viridian Therapeutics
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.86
Ionis Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.73

Ionis Pharmaceuticals has a net margin of -64.76% compared to Viridian Therapeutics' net margin of -505.86%. Viridian Therapeutics' return on equity of -72.97% beat Ionis Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Viridian Therapeutics-505.86% -72.97% -42.80%
Ionis Pharmaceuticals -64.76%-111.08%-17.41%

Viridian Therapeutics has a beta of 0.91, indicating that its share price is 9% less volatile than the broader market. Comparatively, Ionis Pharmaceuticals has a beta of 0.41, indicating that its share price is 59% less volatile than the broader market.

In the previous week, Ionis Pharmaceuticals had 8 more articles in the media than Viridian Therapeutics. MarketBeat recorded 18 mentions for Ionis Pharmaceuticals and 10 mentions for Viridian Therapeutics. Ionis Pharmaceuticals' average media sentiment score of 1.08 beat Viridian Therapeutics' score of 1.04 indicating that Ionis Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Viridian Therapeutics
8 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Ionis Pharmaceuticals
9 Very Positive mention(s)
2 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Viridian Therapeutics beats Ionis Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Viridian Therapeutics compare to Cytokinetics?

Viridian Therapeutics (NASDAQ:VRDN) and Cytokinetics (NASDAQ:CYTK) are both mid-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their analyst recommendations, earnings, profitability, media sentiment, institutional ownership, dividends, valuation and risk.

In the previous week, Viridian Therapeutics had 2 more articles in the media than Cytokinetics. MarketBeat recorded 10 mentions for Viridian Therapeutics and 8 mentions for Cytokinetics. Viridian Therapeutics' average media sentiment score of 1.04 beat Cytokinetics' score of 0.65 indicating that Viridian Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Viridian Therapeutics
8 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Cytokinetics
4 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Viridian Therapeutics has higher earnings, but lower revenue than Cytokinetics. Cytokinetics is trading at a lower price-to-earnings ratio than Viridian Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Viridian Therapeutics$70.85M38.84-$342.60M-$3.37N/A
Cytokinetics$88.04M108.60-$784.96M-$7.22N/A

Viridian Therapeutics has a beta of 0.91, indicating that its stock price is 9% less volatile than the broader market. Comparatively, Cytokinetics has a beta of 0.38, indicating that its stock price is 62% less volatile than the broader market.

Viridian Therapeutics has a net margin of -505.86% compared to Cytokinetics' net margin of -1,321.12%. Cytokinetics' return on equity of 0.00% beat Viridian Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Viridian Therapeutics-505.86% -72.97% -42.80%
Cytokinetics -1,321.12%N/A -51.01%

Viridian Therapeutics currently has a consensus target price of $38.93, indicating a potential upside of 60.27%. Cytokinetics has a consensus target price of $102.20, indicating a potential upside of 33.00%. Given Viridian Therapeutics' higher probable upside, research analysts clearly believe Viridian Therapeutics is more favorable than Cytokinetics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Viridian Therapeutics
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.86
Cytokinetics
1 Sell rating(s)
1 Hold rating(s)
19 Buy rating(s)
0 Strong Buy rating(s)
2.86

Summary

Viridian Therapeutics beats Cytokinetics on 9 of the 13 factors compared between the two stocks.

How does Viridian Therapeutics compare to Spyre Therapeutics?

Viridian Therapeutics (NASDAQ:VRDN) and Spyre Therapeutics (NASDAQ:SYRE) are both mid-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their analyst recommendations, valuation, earnings, profitability, media sentiment, institutional ownership, risk and dividends.

Spyre Therapeutics has a net margin of 0.00% compared to Viridian Therapeutics' net margin of -505.86%. Spyre Therapeutics' return on equity of -30.74% beat Viridian Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Viridian Therapeutics-505.86% -72.97% -42.80%
Spyre Therapeutics N/A -30.74%-22.23%

In the previous week, Viridian Therapeutics had 5 more articles in the media than Spyre Therapeutics. MarketBeat recorded 10 mentions for Viridian Therapeutics and 5 mentions for Spyre Therapeutics. Viridian Therapeutics' average media sentiment score of 1.04 beat Spyre Therapeutics' score of 0.43 indicating that Viridian Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Viridian Therapeutics
8 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Spyre Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Viridian Therapeutics currently has a consensus target price of $38.93, indicating a potential upside of 60.27%. Spyre Therapeutics has a consensus target price of $111.69, indicating a potential upside of 4.89%. Given Viridian Therapeutics' higher probable upside, equities analysts plainly believe Viridian Therapeutics is more favorable than Spyre Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Viridian Therapeutics
1 Sell rating(s)
0 Hold rating(s)
13 Buy rating(s)
0 Strong Buy rating(s)
2.86
Spyre Therapeutics
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87

Viridian Therapeutics has a beta of 0.91, suggesting that its share price is 9% less volatile than the broader market. Comparatively, Spyre Therapeutics has a beta of 3.03, suggesting that its share price is 203% more volatile than the broader market.

Spyre Therapeutics has lower revenue, but higher earnings than Viridian Therapeutics. Spyre Therapeutics is trading at a lower price-to-earnings ratio than Viridian Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Viridian Therapeutics$70.85M38.84-$342.60M-$3.37N/A
Spyre Therapeutics$890K10,522.17-$155.20M-$1.95N/A

80.4% of Spyre Therapeutics shares are held by institutional investors. 2.4% of Viridian Therapeutics shares are held by insiders. Comparatively, 15.7% of Spyre Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Summary

Spyre Therapeutics beats Viridian Therapeutics on 11 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding VRDN and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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VRDN vs. The Competition

MetricViridian TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$2.75B$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio-7.2111.62272.6024.24
Price / Sales38.841,338.17618.9699.81
Price / CashN/A105.1478.6253.99
Price / Book4.8816.8013.056.20
Net Income-$342.60M-$12.50M$3.47B$348.59M
7 Day Performance10.01%3.29%2.09%0.08%
1 Month Performance26.12%8.23%6.64%3.88%
1 Year Performance26.31%55.05%25.02%16.98%

Viridian Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
VRDN
Viridian Therapeutics
2.7268 of 5 stars
$24.29
-0.9%
$38.93
+60.3%
+26.3%$2.75B$70.85MN/A50
KRYS
Krystal Biotech
4.1259 of 5 stars
$335.73
+1.0%
$365.40
+8.8%
+130.3%$9.83B$440.48M42.07210
NUVL
Nuvalent
2.121 of 5 stars
$123.96
flat
$127.73
+3.0%
N/A$9.79BN/AN/A40
IONS
Ionis Pharmaceuticals
3.5688 of 5 stars
$58.63
+2.4%
$94.65
+61.4%
+39.9%$9.51B$944MN/A1,402
CYTK
Cytokinetics
3.3743 of 5 stars
$75.87
+2.3%
$102.20
+34.7%
+100.4%$9.44B$67.67MN/A250

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This page (NASDAQ:VRDN) was last updated on 8/23/2026 by MarketBeat.com Staff.
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