X4 Pharmaceuticals (XFOR) Stock Price, News & Analysis

Company Overview

X4 Pharmaceuticals, Inc., a late-stage clinical biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases. Its lead product candidate is mavorixafor, a small molecule inhibitor of the chemokine receptor C-X-C chemokine receptor type 4 (CXCR4), which is in Phase III clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome; and Phase II clinical trial to treat congenital, idiopathic, or cyclic neutropenia. The company is also developing X4P-003, a CXCR4 antagonist for the treatment of CXCR4 dependent disorders and primary immunodeficiencies; and X4P-002, a CXCR4 antagonist for the treatment of blood-brain barrier diseases. It has a license agreement with Abbisko Therapeutics Co Ltd. to develop, manufacture, and commercialize mavorixafor in combination with checkpoint inhibitors or other agents in oncology indications. The company is headquartered in Boston, Massachusetts.

Key Stats

• Today's Range: $2.77 to $3.00
• 50-Day Range: $1.42 to $3.20
• 52-Week Range: $1.35 to $26.83
• Volume: 1.11 million shs
• Average Volume: 1.65 million shs
• Market Capitalization: $15.89 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $71.17
• Consensus Rating: Buy

X4 Pharmaceuticals Stock Analysis - MarketRank™

X4 Pharmaceuticals scored higher than 82% of companies evaluated by MarketBeat, and ranked 185th out of 941 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.5 / 5
• Analyst Rating: Buy

Consensus Rating

X4 Pharmaceuticals has received a consensus rating of Buy. The company's average rating score is 3.00, and is based on 3 buy ratings, no hold ratings, and no sell ratings.

Amount of Analyst Coverage

X4 Pharmaceuticals has only been the subject of 1 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for X4 Pharmaceuticals are expected to grow in the coming year, from ($0.68) to ($0.51) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of X4 Pharmaceuticals is -0.19, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of X4 Pharmaceuticals is -0.19, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

X4 Pharmaceuticals has a P/B Ratio of 4.20. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

26.22% of the float of X4 Pharmaceuticals has been sold short.

Short Interest Ratio / Days to Cover

X4 Pharmaceuticals has a short interest ratio ("days to cover") of 1.2, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in X4 Pharmaceuticals has recently increased by 161.27%, indicating that investor sentiment is decreasing significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

X4 Pharmaceuticals does not currently pay a dividend.

Dividend Growth

X4 Pharmaceuticals does not have a long track record of dividend growth.

Sustainability and ESG

• Score: 4.6 / 5
• Environmental Score: -0.85

Percentage of Shares Shorted

26.22% of the float of X4 Pharmaceuticals has been sold short.

Short Interest Ratio / Days to Cover

X4 Pharmaceuticals has a short interest ratio ("days to cover") of 1.2, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in X4 Pharmaceuticals has recently increased by 161.27%, indicating that investor sentiment is decreasing significantly.

News and Social Media

• Score: 2.4 / 5
• News Sentiment: 0.26

News Sentiment

X4 Pharmaceuticals has a news sentiment score of 0.26. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.47 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 15 news articles for X4 Pharmaceuticals this week, compared to 2 articles on an average week.

Search Interest

12 people have searched for XFOR on MarketBeat in the last 30 days. This is an increase of 140% compared to the previous 30 days.

MarketBeat Follows

Only 6 people have added X4 Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is a decrease of 0% compared to the previous 30 days.

Company Ownership

• Score: 1.7 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, X4 Pharmaceuticals insiders have not sold or bought any company stock.

Percentage Held by Insiders

Only 2.15% of the stock of X4 Pharmaceuticals is held by insiders.

Percentage Held by Institutions

72.03% of the stock of X4 Pharmaceuticals is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

XFOR Stock Analysis - Frequently Asked Questions

How have XFOR shares performed this year?

X4 Pharmaceuticals' stock was trading at $22.0080 at the start of the year. Since then, XFOR stock has decreased by 86.8% and is now trading at $2.8950.

How were X4 Pharmaceuticals' earnings last quarter?

X4 Pharmaceuticals, Inc. (NASDAQ:XFOR) issued its quarterly earnings results on Friday, August, 8th. The company reported ($3.47) earnings per share (EPS) for the quarter, beating analysts' consensus estimates of ($4.53) by $1.06. The business had revenue of $1.97 million for the quarter, compared to analyst estimates of $1.62 million. X4 Pharmaceuticals had a negative trailing twelve-month return on equity of 375.31% and a negative net margin of 311.15%.

When did X4 Pharmaceuticals' stock split?

X4 Pharmaceuticals's stock reverse split on Monday, April 28th 2025.The 1-30 reverse split was announced on Thursday, April 24th 2025. The number of shares owned by shareholders was adjusted after the closing bell on Friday, April 25th 2025. An investor that had 100 shares of stock prior to the reverse split would have 3 shares after the split.

Who are X4 Pharmaceuticals' major shareholders?

X4 Pharmaceuticals' top institutional investors include Bain Capital Life Sciences Investors LLC (9.74%), Acorn Capital Advisors LLC (2.66%), Jane Street Group LLC (1.68%) and OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC (1.38%). Insiders that own company stock include Paula Ragan, Mark Baldry, Mary Dibiase, Arthur Taveras, Tuvia Barlev, Murray Stewart, Michael S Wyzga, Israel Niv and Adam S Mostafa.
View institutional ownership trends.

How do I buy shares of X4 Pharmaceuticals?

Shares of XFOR stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of X4 Pharmaceuticals own?

Based on aggregate information from My MarketBeat watchlists, some other companies that X4 Pharmaceuticals investors own include Meta Platforms (META), NVIDIA (NVDA), Advanced Micro Devices (AMD), Tesla (TSLA), JPMorgan Chase & Co. (JPM), Netflix (NFLX) and Intel (INTC).

Company Calendar

• Last Earnings: 8/08/2025
• Today: 8/20/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:XFOR
• CIK: 1501697
• Web: www.x4pharma.com
• Phone: (857) 529-8300
• Fax: N/A
• Employees: 80
• Year Founded: N/A

Price Target and Rating

• Average Price Target for X4 Pharmaceuticals: $71.17
• High Price Target: $120.00
• Low Price Target: $3.50
• Potential Upside/Downside: +2,328.9%
• Consensus Rating: Buy
• Rating Score (0-4): 3.00
• Research Coverage: 3 Analysts

Profitability

• EPS (Trailing Twelve Months): ($14.84)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$37.45 million
• Net Margins: -311.15%
• Pretax Margin: -310.10%
• Return on Equity: -375.31%
• Return on Assets: -72.87%

Debt

• Debt-to-Equity Ratio: 19.10
• Current Ratio: 3.19
• Quick Ratio: 3.05

Sales & Book Value

• Annual Sales: $2.56 million
• Price / Sales: 6.63
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $0.69 per share
• Price / Book: 4.25

Miscellaneous

• Outstanding Shares: 5,790,000
• Free Float: 5,665,000
• Market Cap: $16.96 million
• Optionable: Optionable
• Beta: 0.60