Alto Neuroscience (ANRO) Stock Price, News & Analysis

Company Overview

Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. Its product pipeline comprising ALTO-100, which is in phase 2b clinical trial for the treatment of patients with major depressive disorder (MDD); and which is in phase 2a clinical trial for the treatment of post-traumatic stress disorder. The company develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties which is in phase 2b clinical trial to treat patients with MDD; ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor which is in phase 1 clinical trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist which is in phase 1 clinical trial to treat patients with MDD and higher levels of anhedonia; and ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor which is in phase 1 clinical trial for the treatment of MDD. In addition, it develops novel pharmacodynamically synergistic combination and biomarker platform that collects patient-specific data to identify biomarker-characterized patient. The company was incorporated in 2019 and is headquartered in Los Altos, California.

Key Stats

• Today's Range: $2.21 to $2.33
• 50-Day Range: $2.11 to $3.05
• 52-Week Range: $1.60 to $17.55
• Volume: 149,415 shs
• Average Volume: 394,620 shs
• Market Capitalization: $61.18 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $15.40
• Consensus Rating: Moderate Buy

Alto Neuroscience Stock Analysis - MarketRank™

Alto Neuroscience scored higher than 30% of companies evaluated by MarketBeat, and ranked 632nd out of 930 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.3 / 5
• Analyst Rating: Moderate Buy

Consensus Rating

Alto Neuroscience has received a consensus rating of Moderate Buy. The company's average rating score is 2.57, and is based on 4 buy ratings, 3 hold ratings, and no sell ratings.

Amount of Analyst Coverage

Alto Neuroscience has only been the subject of 2 research reports in the past 90 days.

Earnings and Valuation

• Score: 1.3 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Alto Neuroscience are expected to grow in the coming year, from ($2.54) to ($2.39) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Alto Neuroscience is -0.97, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Alto Neuroscience is -0.97, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Alto Neuroscience has a P/B Ratio of 0.40. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.

Short Interest

• Score: 1.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

13.68% of the float of Alto Neuroscience has been sold short.

Short Interest Ratio / Days to Cover

Alto Neuroscience has a short interest ratio ("days to cover") of 11.6, which indicates bearish sentiment.

Change versus previous month

Short interest in Alto Neuroscience has recently decreased by 2.33%, indicating that investor sentiment is improving.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Alto Neuroscience does not currently pay a dividend.

Dividend Growth

Alto Neuroscience does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

13.68% of the float of Alto Neuroscience has been sold short.

Short Interest Ratio / Days to Cover

Alto Neuroscience has a short interest ratio ("days to cover") of 11.6, which indicates bearish sentiment.

Change versus previous month

Short interest in Alto Neuroscience has recently decreased by 2.33%, indicating that investor sentiment is improving.

News and Social Media

• Score: 0.6 / 5
• News Sentiment: N/A

Search Interest

Only 8 people have searched for ANRO on MarketBeat in the last 30 days. This is a decrease of -11% compared to the previous 30 days.

MarketBeat Follows

1 people have added Alto Neuroscience to their MarketBeat watchlist in the last 30 days.

Company Ownership

• Score: 0.8 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Alto Neuroscience insiders have not sold or bought any company stock.

Percentage Held by Insiders

11.13% of the stock of Alto Neuroscience is held by insiders. A high percentage of insider ownership can be a sign of company health.

ANRO Stock Analysis - Frequently Asked Questions

How have ANRO shares performed this year?

Alto Neuroscience's stock was trading at $4.23 at the beginning of the year. Since then, ANRO shares have decreased by 46.6% and is now trading at $2.26.
View the best growth stocks for 2025 here.

How were Alto Neuroscience's earnings last quarter?

Alto Neuroscience, Inc. (NYSE:ANRO) issued its quarterly earnings results on Tuesday, May, 13th. The company reported ($0.53) earnings per share (EPS) for the quarter, beating the consensus estimate of ($0.59) by $0.06.

When did Alto Neuroscience IPO?

Alto Neuroscience (ANRO) raised $129 million in an initial public offering (IPO) on Friday, February 2nd 2024. The company issued 8,040,000 shares at $16.00 per share.

Who are Alto Neuroscience's major shareholders?

Alto Neuroscience's top institutional investors include Armistice Capital LLC (5.91%), AWM Investment Company Inc. (3.33%), Woodline Partners LP (1.33%) and Almitas Capital LLC (0.87%). Insiders that own company stock include Wave Global Lp Alpha, Adam Savitz and Nicholas Conrad Smith.
View institutional ownership trends.

How do I buy shares of Alto Neuroscience?

Shares of ANRO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Alto Neuroscience own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Alto Neuroscience investors own include JPMorgan Chase & Co. (JPM), Tesla (TSLA), Meta Platforms (META), NVIDIA (NVDA), Advanced Micro Devices (AMD), Netflix (NFLX) and Alphabet (GOOG).

Company Calendar

• Last Earnings: 5/13/2025
• Today: 6/20/2025
• Next Earnings (Estimated): 8/12/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NYSE
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NYSE:ANRO
• Previous Symbol: NYSE:ANRO
• CIK: 1999480
• Web: www.altoneuroscience.com
• Phone: (650) 200-0412
• Fax: N/A
• Employees: N/A
• Year Founded: N/A

Price Target and Rating

• Average Stock Price Target: $15.40
• High Stock Price Target: $43.00
• Low Stock Price Target: $4.00
• Potential Upside/Downside: +581.4%
• Consensus Rating: Moderate Buy
• Rating Score (0-4): 2.57
• Research Coverage: 7 Analysts

Profitability

• EPS (Most Recent Fiscal Year): ($2.34)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$61.43 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -39.35%
• Return on Assets: -33.86%

Debt

• Debt-to-Equity Ratio: 0.15
• Current Ratio: 22.53
• Quick Ratio: 22.53

Sales & Book Value

• Annual Sales: N/A
• Price / Sales: N/A
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $5.62 per share
• Price / Book: 0.40

Miscellaneous

• Outstanding Shares: 27,070,000
• Free Float: 24,059,000
• Market Cap: $61.18 million
• Optionable: N/A
• Beta: 1.93