Arcus Biosciences is a clinical-stage biopharmaceutical company focused on developing next-generation cancer immunotherapies. The company’s research platform centers on modulating the tumor microenvironment to enhance anti-tumor immune responses. Arcus’s lead product candidates target immune checkpoints and adenosine pathways, with the goal of improving efficacy and overcoming resistance observed with existing therapies.
The company’s pipeline includes zimberelimab, a monoclonal anti-PD-1 antibody; domvanalimab, an anti-TIGIT antibody; and etrumadenant, a dual A2A/A2B adenosine receptor antagonist. These candidates are being studied both as monotherapies and in combination regimens across a range of solid tumors. Arcus leverages translational biomarkers to guide patient selection and optimize dosing strategies in its ongoing global clinical trials.
To advance its pipeline, Arcus has established strategic collaborations, including a partnership with Incyte to develop and commercialize its dual adenosine receptor antagonist program. The company also maintains clinical trial sites across North America, Europe and Asia, reflecting its commitment to broad patient access and global development.
Founded in 2015 and headquartered in Hayward, California, Arcus Biosciences is led by a management team with extensive experience in oncology drug development. The company’s board and scientific advisory members bring deep expertise in immunology and translational medicine, supporting its mission to deliver transformative treatments for cancer patients worldwide.
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