NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $30.64 +0.38 (+1.26%) As of 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartHoldingsOwnershipRatingsShort InterestBuy This Stock About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get SBIO alerts:Sign Up Key Stats Today's Range$30.40▼$30.7350-Day Range$27.22▼$31.7652-Week Range$22.33▼$42.73Volume5,925 shsAverage Volume12,499 shsMarket Capitalization$74.30 millionAssets Under Management$73.43 millionDividend Yield3.82%Net Expense Ratio0.50%Aggregate RatingModerate Buy ETF Overview The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS. Read More ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.56%0.56%0.51%0.53%Other Expenses0.00%0.47%0.56%0.59%0.56%Total Expense0.50%0.75%0.76%0.74%0.73%Fee Waiver0.00%-0.67%-0.66%-0.71%-0.63%Net Expense0.50%0.60%0.63%0.58%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Email Address SBIO ETF News HeadlinesALPS MEDICAL BREAKTHROUGHS ETF ETFs - Markets InsiderJuly 3, 2025 | markets.businessinsider.comSBIO ETF: Betting On Medical BreakthroughsDecember 14, 2024 | seekingalpha.comA grave, grave error.I thought what happened 25 years ago was a once- in-a-lifetime event… but how wrong I was. Because here we are, a quarter of a century later, almost to the exact day, and it’s happening again. July 8 at 2:00 AM | Porter & Company (Ad)Advacam & Vector Space Biosciences sign Letter of Intent (LOI) to Develop AI Models & CubeSat Payloads for the Space IndustryOctober 10, 2024 | businesswire.comWhy Biotech ETFs Are Beating the MarketSeptember 7, 2024 | msn.comALPS Medical Breakthroughs ETF (^SBIO-IV)July 19, 2024 | finance.yahoo.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $33.03 at the start of the year. Since then, SBIO shares have decreased by 7.2% and is now trading at $30.64. How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AU Optronics (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/31/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings109 Fund Statistics Assets Under Management$73.43 million Average Daily Volume$26.67 thousand Discount/Premium-0.02% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Portfolio Solutions Distributor, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableOptionable Options Volume2 Put Options8 Call Options2 Short Interest2,300 shs Miscellaneous Outstanding Shares2,425,000Beta0.92 Creation Unit50,000 Creation Fee$500.00 Investing Strategies To Help Grow Your Retirement IncomeNeed to stretch out your 401K or Roth IRA plan? Use these time-tested investing strategies to grow the monthly retirement income that your stock portfolio generates.Get This Free Report Top 10 SBIO HoldingsVerona Pharma PLC American Depositary Share (NASDAQ:VRNA)Holding Weight: 6.33%Alkermes (NASDAQ:ALKS)Holding Weight: 3.92%Axsome Therapeutics (NASDAQ:AXSM)Holding Weight: 3.85%Akero Therapeutics (NASDAQ:AKRO)Holding Weight: 3.68%PTC Therapeutics (NASDAQ:PTCT)Holding Weight: 3.34%Rhythm Pharmaceuticals (NASDAQ:RYTM)Holding Weight: 3.29%Zai Lab (NASDAQ:ZLAB)Holding Weight: 3.26%ACADIA Pharmaceuticals (NASDAQ:ACAD)Holding Weight: 3.17%Merus (NASDAQ:MRUS)Holding Weight: 3.10%Avidity Biosciences (NASDAQ:RNA)Holding Weight: 2.96%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 7/8/2025 by MarketBeat.com Staff From Our PartnersThis Signal Only Flashes Once Every 4 Years – And It Just TriggeredThis same signal has appeared twice before in the past 8 years — both times, it kicked off major moves in cryp...Crypto Swap Profits | SponsoredINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredBuffett’s $325 Billion Cash Problem — Solved by Gold?A bombshell announcement is just weeks away — and it could send shockwaves through the gold market. 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