NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $67.22 -1.72 (-2.49%) As of 07/10/2026 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartHoldingsOwnershipRatingsShort InterestBuy This Stock About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SBIO alerts:Sign Up Key Stats Today's Range$65.57▼$69.3450-Day Range$50.31▼$68.9452-Week Range$32.21▼$69.34Volume61,817 shsAverage Volume37,322 shsMarket Capitalization$203.68 millionAssets Under Management$213.08 millionDividend YieldN/ANet Expense Ratio0.50%Aggregate RatingModerate Buy ETF Overview The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS. Read More ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.56%0.57%0.51%0.53%Other Expenses0.00%0.47%0.55%0.58%0.55%Total Expense0.50%0.74%0.76%0.74%0.73%Fee Waiver0.00%-0.71%-0.64%-0.70%-0.62%Net Expense0.50%0.59%0.63%0.58%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. 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SBIO ETF News HeadlinesSBIO: Biotech Breakthrough Opportunities Screened For Cash BurnJuly 7, 2026 | seekingalpha.comCREATOR TV SPORTS™ UNVEILS CREATOR LINEUP FOR INAUGURAL "CREATOR PICKLEBALL TOUR" AT VIDCON ANAHEIMJune 15, 2026 | prnewswire.comA letter from Shannon StansberryPorter Stansberry nearly canceled the entire project. When he first saw the claimed returns - only one down year in nearly two decades and total gains of almost 2,000% - his immediate reaction was disbelief. It took a trusted friend's personal vouching for Emmet Savage and a face-to-face trip to Ireland to change his mind. The full documentary, Investigating Project Prophet, is now live.July 12 at 1:00 AM | Porter & Company (Ad)SBIO: Leaning Into Drug Discovery And Medical BreakthroughsApril 28, 2026 | seekingalpha.comCreator TV® Announces 2026 Sports Programming under Studio Label, Creator TV SportsApril 2, 2026 | prnewswire.comCreator TV® and Convergence Announce Partnership to Bring Creator-Led Programming to TelevisionMarch 25, 2026 | prnewswire.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $51.22 on January 1st, 2026. Since then, SBIO stock has increased by 31.2% and is now trading at $67.22. Who are ALPS Medical Breakthroughs ETF's major shareholders? Top institutional shareholders of ALPS Medical Breakthroughs ETF include Fulcrum Equity Management (0.14%) and Harbor Investment Advisory LLC (0.02%). How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AUO (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/30/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings109 Fund Statistics Assets Under Management$213.08 million Average Daily Volume$48.10 thousand Discount/Premium0.11% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Distributors, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableOptionable Options Volume9 Put Options0 Call Options9 Short Interest96,526 shs Miscellaneous Outstanding Shares3,030,000Beta0.73 Creation Unit50,000 Creation Fee$500.00 7 Stocks to Buy And Hold ForeverClick the link to see MarketBeat's list of seven stocks and why their long-term outlooks are very promising. Get This Free Report Top 10 SBIO HoldingsCrinetics Pharmaceuticals (NASDAQ:CRNX)Holding Weight: 4.38%Apogee Therapeutics (NASDAQ:APGE)Holding Weight: 4.11%Xenon Pharmaceuticals (NASDAQ:XENE)Holding Weight: 3.41%CG Oncology (NASDAQ:CGON)Holding Weight: 3.22%Dianthus Therapeutics (NASDAQ:DNTH)Holding Weight: 2.72%Travere Therapeutics (NASDAQ:TVTX)Holding Weight: 2.70%Oruka Therapeutics (NASDAQ:ORKA)Holding Weight: 2.65%Definium Therapeutics (NASDAQ:DFTX)Holding Weight: 2.63%Edgewise Therapeutics (NASDAQ:EWTX)Holding Weight: 2.59%Veradermics (NYSE:MANE)Holding Weight: 2.59%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 7/12/2026 by MarketBeat.com Staff. From Our PartnersIt’s one of Trump’s biggest holdings. 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