NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $54.22 -2.04 (-3.63%) As of 10:34 AM Eastern This is a fair market value price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHoldingsNews and TrendsOwnershipRatingsShort Interest About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SBIO alerts:Sign Up Key Stats Today's Range$54.32▼$56.2850-Day Range$56.15▼$70.7952-Week Range$39.52▼$70.85Volume10,714 shsAverage Volume38,102 shsMarket Capitalization$196.67 millionAssets Under Management$197.06 millionDividend YieldN/ANet Expense Ratio0.50%Aggregate RatingModerate Buy ETF Overview The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS. Read More ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.55%0.57%0.50%0.53%Other Expenses0.00%0.52%0.53%0.60%0.54%Total Expense0.50%0.76%0.75%0.75%0.73%Fee Waiver0.00%-0.85%-0.67%-0.78%-0.68%Net Expense0.50%0.58%0.63%0.57%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. 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SBIO ETF News HeadlinesSBIO: Promising Pipelines, Insufficient Return PotentialSeptember 25, 2026 | seekingalpha.comALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) Sees Significant Drop in Short InterestSeptember 25, 2026 | americanbankingnews.comElon Musk’s One Stock Retirement PlanStanley Druckenmiller once said you don't get rich diversifying into 50 mediocre assets - you get rich finding two or three asymmetric home runs. Analyst Jeff Brown says he has identified a new one, a single stock he calls Elon Musk's One Stock Retirement Plan.October 6 at 1:00 AM | Brownstone Research (Ad)SBIO: Big Pharma Needs What This Fund OwnsSeptember 22, 2026 | seekingalpha.com(SBIO) ALPS Medical Breakthroughs ETFAugust 29, 2026 | sa.investing.comSBIO: Dividendenhistorie, Rendite und Ex-Dividenden-TagAugust 22, 2026 | de.investing.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $51.22 at the start of the year. Since then, SBIO stock has increased by 9.8% and is now trading at $56.26. How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AUO (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/30/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings106 Fund Statistics Assets Under Management$197.06 million Average Daily Volume$43.04 thousand Discount/Premium-0.04% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Distributors, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableN/A Short Interest13,369 shs Miscellaneous Outstanding Shares3,620,000Beta0.76 Creation Unit50,000 Creation Fee$500.00 Don't Wait for the OpenAI IPOThe AI wave will soon hit public markets with Anthropic and OpenAI set to go public later this year. However, you don't have to wait to invest. This report shows seven AI stocks that you can buy today while the big model providers get ready to go public.Get This Free Report Top 10 SBIO HoldingsCG Oncology (NASDAQ:CGON)Holding Weight: 3.90%Oruka Therapeutics (NASDAQ:ORKA)Holding Weight: 3.56%Travere Therapeutics (NASDAQ:TVTX)Holding Weight: 3.45%Definium Therapeutics (NASDAQ:DFTX)Holding Weight: 3.25%Dianthus Therapeutics (NASDAQ:DNTH)Holding Weight: 3.18%Veradermics (NYSE:MANE)Holding Weight: 3.15%Edgewise Therapeutics (NASDAQ:EWTX)Holding Weight: 2.83%Relay Therapeutics (NASDAQ:RLAY)Holding Weight: 2.61%Xenon Pharmaceuticals (NASDAQ:XENE)Holding Weight: 2.43%IDEAYA Biosciences (NASDAQ:IDYA)Holding Weight: 2.35%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 10/6/2026 by MarketBeat.com Staff. From Our PartnersA weekly dividend fund holding Nvidia and PalantirCrowdStrike, Palantir, Nvidia none of them pay a real dividend. 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