NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $63.71 +0.42 (+0.66%) Closing price 09/14/2026 04:10 PM EasternExtended Trading$64.27 +0.56 (+0.88%) As of 07:00 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHoldingsNews and TrendsOwnershipRatingsShort Interest About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SBIO alerts:Sign Up Key Stats Today's Range$63.51▼$64.5250-Day Range$63.14▼$70.7952-Week Range$35.43▼$70.85Volume16,192 shsAverage Volume37,434 shsMarket Capitalization$201.96 millionAssets Under Management$232.86 millionDividend YieldN/ANet Expense Ratio0.50%Aggregate RatingModerate Buy ETF Overview The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS. Read More ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.55%0.57%0.50%0.53%Other Expenses0.00%0.52%0.53%0.60%0.54%Total Expense0.50%0.76%0.75%0.75%0.73%Fee Waiver0.00%-0.85%-0.67%-0.78%-0.68%Net Expense0.50%0.58%0.63%0.57%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. SBIO ETF News Headlines(SBIO) ALPS Medical Breakthroughs ETFAugust 29, 2026 | sa.investing.comSBIO: Dividendenhistorie, Rendite und Ex-Dividenden-TagAugust 22, 2026 | de.investing.comReady to give options a try? Your first trade (Ticker included) -INSIDETired of trying tactic after tactic when it comes to options trades... only to be met with market noise and stinging losses? Dave Aquino is giving away the exact 11-hour options strategy he uses in volatile markets. You get the plain English blueprint behind the strategy and the very same "rinse and repeat" ticker he's traded nearly 900 times with a 95.3% success rate. It's so simple to understand, you could trade it tomorrow.September 15 at 1:00 AM | Base Camp Trading (Ad)SBIO: Biotech Breakthrough Opportunities Screened For Cash BurnJuly 7, 2026 | seekingalpha.comCREATOR TV SPORTS™ UNVEILS CREATOR LINEUP FOR INAUGURAL "CREATOR PICKLEBALL TOUR" AT VIDCON ANAHEIMJune 15, 2026 | prnewswire.comSBIO: Leaning Into Drug Discovery And Medical BreakthroughsApril 28, 2026 | seekingalpha.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $51.22 at the beginning of 2026. Since then, SBIO shares have increased by 24.4% and is now trading at $63.71. Who are ALPS Medical Breakthroughs ETF's major shareholders? ALPS Medical Breakthroughs ETF's top institutional investors include Sterling Investment Advisors Ltd. (0.75%), Fulcrum Equity Management (0.14%) and Harbor Investment Advisory LLC (0.02%). How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AUO (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/30/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings107 Fund Statistics Assets Under Management$232.86 million Average Daily Volume$38.24 thousand Discount/Premium-0.07% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Distributors, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableN/A Short Interest61,681 shs Miscellaneous Outstanding Shares3,170,000Beta0.74 Creation Unit50,000 Creation Fee$500.00 Don't Wait for the OpenAI IPOThe AI wave will soon hit public markets with Anthropic and OpenAI set to go public later this year. However, you don't have to wait to invest. This report shows seven AI stocks that you can buy today while the big model providers get ready to go public.Get This Free Report Top 10 SBIO HoldingsCG Oncology (NASDAQ:CGON)Holding Weight: 3.65%Travere Therapeutics (NASDAQ:TVTX)Holding Weight: 3.37%Dianthus Therapeutics (NASDAQ:DNTH)Holding Weight: 3.28%Xenon Pharmaceuticals (NASDAQ:XENE)Holding Weight: 3.20%Oruka Therapeutics (NASDAQ:ORKA)Holding Weight: 3.10%ACADIA Pharmaceuticals (NASDAQ:ACAD)Holding Weight: 2.66%Edgewise Therapeutics (NASDAQ:EWTX)Holding Weight: 2.57%Definium Therapeutics (NASDAQ:DFTX)Holding Weight: 2.30%Relay Therapeutics (NASDAQ:RLAY)Holding Weight: 2.30%Veradermics (NYSE:MANE)Holding Weight: 2.28%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 9/15/2026 by MarketBeat.com Staff. 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