ALPS Medical Breakthroughs ETF (SBIO) Holdings List

$59.85 -3.50 (-5.52%)

Closing price 09/23/2026 04:10 PM Eastern

Extended Trading

$63.36 +3.51 (+5.86%)

As of 08:33 AM Eastern

What stocks does SBIO hold?

The ALPS Medical Breakthroughs ETF (SBIO) top stock holdings include CG Oncology, Oruka Therapeutics, and Travere Therapeutics. The top 25 SBIO holdings ordered by weight make up 55.96% of the total fund. SBIO is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete SBIO stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 SBIO Holdings

Rank	Company	Current Price	Weight	Shares Held
1	CGON CG Oncology	$73.36 -5.6%	3.86%	116,606
2	ORKA Oruka Therapeutics	$89.93 -4.9%	3.67%	87,095
3	TVTX Travere Therapeutics	$59.83 -0.7%	3.45%	123,993
4	DNTH Dianthus Therapeutics	$93.44 -5.0%	3.16%	73,582
5	DFTX Definium Therapeutics	$37.65 -6.6%	3.04%	176,756
6	EWTX Edgewise Therapeutics	$41.05 -7.8%	2.87%	142,864
7	ACAD ACADIA Pharmaceuticals	$25.43 -3.7%	2.74%	226,658
8	MANE Veradermics	$115.73 -2.0%	2.60%	54,956
9	RLAY Relay Therapeutics	$18.03 -6.8%	2.41%	288,271
10	AMLX Amylyx Pharmaceuticals	$30.60 -7.3%	2.37%	165,103
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11	XENE Xenon Pharmaceuticals	$36.56 -6.5%	2.24%	127,389
12	IDYA IDEAYA Biosciences	$37.46 -5.7%	2.16%	126,929
13	TARS Tarsus Pharmaceuticals	$74.29 -3.6%	2.00%	57,730
14	DYN Dyne Therapeutics	$16.23 -5.3%	1.86%	245,653
15	DNLI Denali Therapeutics	$20.46 -5.3%	1.84%	210,272
16	MBX MBX Biosciences	$57.89 -6.6%	1.77%	63,350
17	CLDX Celldex Therapeutics	$31.12 -7.1%	1.75%	103,304
18	ZLAB Zai Lab	$26.44 +0.1%	1.68%	147,943
19	IMNM Immunome	$24.24 -5.9%	1.59%	149,402
20	NAMS NewAmsterdam Pharma	$22.68 -2.7%	1.57%	157,248
21	IRON Disc Medicine	$66.09 -3.5%	1.56%	50,506
22	GPCR Structure Therapeutics	$35.95 -2.6%	1.45%	93,799
23	VRDN Viridian Therapeutics	$21.43 -3.1%	1.45%	149,028
24	MLYS Mineralys Therapeutics	$26.89 -8.5%	1.44%	116,294
25	VERA Vera Therapeutics	$33.05 -8.9%	1.43%	94,795

SBIO Geographic Exposure

SBIO's largest geographic exposure is United States at 90.1%, followed by Canada at 5.3%.

United States
90.1%
Canada
5.3%
Netherlands
2.4%
Cayman Islands
0.9%

SBIO Currency Exposure

SBIO is exclusively exposed to USD.

USD
99.5%

SBIO Sector Exposure

SBIO's largest sector exposure is Health Care at 84.8%, followed by Energy at 0.5%.

Health Care
84.8%
Energy
0.5%
Consumer Discretionary
0.4%

SBIO Industry Exposure

SBIO's largest industry exposure is Biotechnology at 67.6%, followed by Pharmaceuticals at 15.3%.

Biotechnology
67.6%
Pharmaceuticals
15.3%
Health Care Equipment & Supplies
1.5%
Renewable Energy
0.5%
Diversified Consumer Services
0.4%
Health Care Providers & Services
0.3%

SBIO Sub-Industry Exposure

SBIO's largest sub-industry exposure is Biotechnology at 63.4%, followed by Pharmaceuticals at 17.9%.

Biotechnology
63.4%
Pharmaceuticals
17.9%
Life Sciences Tools & Services
1.2%
Renewable Energy Equipment
0.5%
Health Care Services
0.3%
Health Care Equipment
0.3%

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MarketBeat tracks ALPS Medical Breakthroughs ETF holdings and portfolio composition, last updated on 9/21/2026.

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ALPS Medical Breakthroughs ETF (SBIO) Holdings List