ALPS Medical Breakthroughs ETF (SBIO) Holdings List

$67.31 -0.58 (-0.85%)

As of 09/3/2026 04:10 PM Eastern

What stocks does SBIO hold?

The ALPS Medical Breakthroughs ETF (SBIO) top stock holdings include Crinetics Pharmaceuticals, Apogee Therapeutics, and Oruka Therapeutics. The top 25 SBIO holdings ordered by weight make up 57.92% of the total fund. SBIO is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete SBIO stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 SBIO Holdings

Rank	Company	Current Price	Weight	Shares Held
1	CRNX Crinetics Pharmaceuticals	$84.95	4.55%	119,051
2	APGE Apogee Therapeutics	$135.10 +0.0%	4.24%	69,943
3	ORKA Oruka Therapeutics	$90.99 -0.7%	3.41%	68,047
4	CGON CG Oncology	$74.33 -0.3%	3.37%	99,688
5	DNTH Dianthus Therapeutics	$107.85 +1.5%	3.23%	61,733
6	XENE Xenon Pharmaceuticals	$60.40 +0.4%	3.07%	109,102
7	TVTX Travere Therapeutics	$66.54 -1.0%	2.94%	105,028
8	ACAD ACADIA Pharmaceuticals	$27.86 -3.7%	2.46%	193,319
9	EWTX Edgewise Therapeutics	$41.95 -0.1%	2.42%	121,692
10	MANE Veradermics	$97.70 -0.8%	2.39%	47,118
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11	DFTX Definium Therapeutics	$38.00 -2.3%	2.37%	123,264
12	RLAY Relay Therapeutics	$19.01 +2.7%	2.20%	245,913
13	DYN Dyne Therapeutics	$24.95 -0.8%	2.17%	186,901
14	GPCR Structure Therapeutics	$47.34 -1.0%	1.98%	80,356
15	DNLI Denali Therapeutics	$22.80 -0.2%	1.97%	179,404
16	CLDX Celldex Therapeutics	$39.37 -0.3%	1.68%	88,573
17	MBX MBX Biosciences	$61.42 +0.9%	1.66%	53,719
18	IDYA IDEAYA Biosciences	$39.97 -0.5%	1.63%	99,300
19	NAMS NewAmsterdam Pharma	$25.85 +1.0%	1.61%	132,159
20	IMNM Immunome	$27.16 -0.6%	1.57%	128,020
21	IRON Disc Medicine	$79.37 -0.8%	1.53%	43,143
22	TARS Tarsus Pharmaceuticals	$83.21 +0.5%	1.51%	48,520
23	ZLAB Zai Lab	$27.00 +2.0%	1.44%	123,035
24	BCRX BioCryst Pharmaceuticals	$10.09 -0.8%	1.26%	287,427
25	NKTR Nektar Therapeutics	$76.37 +5.0%	1.26%	38,234

SBIO Geographic Exposure

SBIO's largest geographic exposure is United States at 89.7%, followed by Canada at 5.6%.

United States
89.7%
Canada
5.6%
Netherlands
2.4%
Cayman Islands
1.5%

SBIO Currency Exposure

SBIO is exclusively exposed to USD.

USD
100.0%

SBIO Sector Exposure

SBIO's largest sector exposure is Health Care at 86.1%, followed by Energy at 0.5%.

Health Care
86.1%
Energy
0.5%
Consumer Discretionary
0.4%

SBIO Industry Exposure

SBIO's largest industry exposure is Biotechnology at 69.0%, followed by Pharmaceuticals at 15.3%.

Biotechnology
69.0%
Pharmaceuticals
15.3%
Health Care Equipment & Supplies
1.5%
Renewable Energy
0.5%
Diversified Consumer Services
0.4%
Health Care Providers & Services
0.3%

SBIO Sub-Industry Exposure

SBIO's largest sub-industry exposure is Biotechnology at 65.1%, followed by Pharmaceuticals at 17.6%.

Biotechnology
65.1%
Pharmaceuticals
17.6%
Life Sciences Tools & Services
1.2%
Renewable Energy Equipment
0.5%
Health Care Equipment
0.3%
Health Care Services
0.3%

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MarketBeat tracks ALPS Medical Breakthroughs ETF holdings and portfolio composition, last updated on 8/28/2026.

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ALPS Medical Breakthroughs ETF (SBIO) Holdings List