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ALPS Medical Breakthroughs ETF (SBIO) Holdings List

ALPS Medical Breakthroughs ETF logo
$51.20 -0.44 (-0.85%)
Closing price 04:10 PM Eastern
Extended Trading
$51.13 -0.07 (-0.14%)
As of 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

What stocks does SBIO hold?

The ALPS Medical Breakthroughs ETF (SBIO) has 106 holdings, with CG Oncology, Oruka Therapeutics, and Travere Therapeutics among its largest positions. The top 25 SBIO holdings ordered by weight make up 57.16% of the total fund. SBIO is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete SBIO stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 SBIO Holdings

RankCompanyCurrent PriceWeightShares Held
1
CG Oncology, Inc. stock logo
CGON
CG Oncology
$61.84
-0.9%
3.90%117,456
2
Oruka Therapeutics, Inc. stock logo
ORKA
Oruka Therapeutics
$76.68
-1.9%
3.56%87,745
3
Travere Therapeutics, Inc. stock logo
TVTX
Travere Therapeutics
$53.27
+2.8%
3.45%124,893
4
Definium Therapeutics, Inc. stock logo
DFTX
Definium Therapeutics
$34.24
-0.4%
3.25%178,006
5
Dianthus Therapeutics, Inc. stock logo
DNTH
Dianthus Therapeutics
$74.76
-3.6%
3.18%74,082
6
Veradermics, Incorporated stock logo
MANE
Veradermics
$112.85
-2.9%
3.15%55,356
7
Edgewise Therapeutics, Inc. stock logo
EWTX
Edgewise Therapeutics
$37.02
+2.0%
2.83%143,864
8
Relay Therapeutics, Inc. stock logo
RLAY
Relay Therapeutics
$17.06
-1.7%
2.61%290,321
9
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$33.90
-1.5%
2.43%128,289
10
IDEAYA Biosciences, Inc. stock logo
IDYA
IDEAYA Biosciences
$33.86
-1.2%
2.35%127,829
11
Amylyx Pharmaceuticals, Inc. stock logo
AMLX
Amylyx Pharmaceuticals
$27.03
+0.7%
2.27%166,303
12
ACADIA Pharmaceuticals Inc. stock logo
ACAD
ACADIA Pharmaceuticals
$19.25
+3.4%
2.21%228,308
13
Tarsus Pharmaceuticals, Inc. stock logo
TARS
Tarsus Pharmaceuticals
$72.29
+2.1%
2.13%58,130
14
Denali Therapeutics Inc. stock logo
DNLI
Denali Therapeutics
$17.87
-2.9%
2.11%211,772
15
Dyne Therapeutics, Inc. stock logo
DYN
Dyne Therapeutics
$15.04
-1.7%
1.90%247,403
16
NewAmsterdam Pharma Company N.V. stock logo
NAMS
NewAmsterdam Pharma
$20.01
-0.9%
1.86%158,398
17
Zai Lab Limited Unsponsored ADR stock logo
ZLAB
Zai Lab
$22.50
-2.6%
1.85%148,993
18
MBX Biosciences, Inc. stock logo
MBX
MBX Biosciences
$48.82
-0.4%
1.75%63,800
19
Celldex Therapeutics, Inc. stock logo
CLDX
Celldex Therapeutics
$27.83
-1.5%
1.63%104,054
20
Disc Medicine, Inc. stock logo
IRON
Disc Medicine
$55.74
-1.5%
1.57%50,856
21
Immunome, Inc. stock logo
IMNM
Immunome
$17.20
-2.2%
1.53%150,502
22
SELLAS Life Sciences Group, Inc. stock logo
SLS
SELLAS Life Sciences Group
$11.88
-4.3%
1.47%267,545
23
Vera Therapeutics, Inc. stock logo
VERA
Vera Therapeutics
$26.74
-0.2%
1.44%95,495
24
Viridian Therapeutics, Inc. stock logo
VRDN
Viridian Therapeutics
$18.38
+0.9%
1.38%150,078
25
Mineralys Therapeutics, Inc. stock logo
MLYS
Mineralys Therapeutics
$20.76
-1.1%
1.35%117,144

SBIO Geographic Exposure

SBIO's largest geographic exposure is United States at 90.2%, followed by Canada at 5.6%.

  • United States
    90.2%
  • Canada
    5.6%
  • Netherlands
    2.4%
  • Cayman Islands
    1.0%

SBIO Currency Exposure

SBIO is exclusively exposed to USD.

  • USD
    100.0%

SBIO Sector Exposure

SBIO's largest sector exposure is Health Care at 85.4%, followed by Energy at 0.4%.

  • Health Care
    85.4%
  • Energy
    0.4%
  • Consumer Discretionary
    0.3%

SBIO Industry Exposure

SBIO's largest industry exposure is Biotechnology at 68.2%, followed by Pharmaceuticals at 15.0%.

  • Biotechnology
    68.2%
  • Pharmaceuticals
    15.0%
  • Health Care Equipment & Supplies
    1.8%
  • Health Care Providers & Services
    0.4%
  • Renewable Energy
    0.4%
  • Diversified Consumer Services
    0.3%

SBIO Sub-Industry Exposure

SBIO's largest sub-industry exposure is Biotechnology at 63.7%, followed by Pharmaceuticals at 17.7%.

  • Biotechnology
    63.7%
  • Pharmaceuticals
    17.7%
  • Life Sciences Tools & Services
    1.5%
  • Health Care Services
    0.4%
  • Health Care Equipment
    0.4%
  • Renewable Energy Equipment
    0.4%

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MarketBeat tracks ALPS Medical Breakthroughs ETF holdings and portfolio composition, last updated on 10/3/2026.
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