NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $31.58 +0.56 (+1.81%) As of 06/6/2025 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartHoldingsOwnershipRatingsShort InterestBuy This Stock About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get SBIO alerts:Sign Up Key Stats Today's Range$31.38▼$31.6750-Day Range$23.59▼$31.5852-Week Range$22.33▼$42.73Volume16,869 shsAverage Volume11,093 shsMarket Capitalization$89.37 millionAssets Under Management$88.48 millionDividend Yield3.70%Net Expense Ratio0.50%Aggregate RatingModerate Buy ETF OverviewThe ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS.Read More… ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.57%0.57%0.52%0.53%Other Expenses0.00%0.30%0.48%0.56%0.51%Total Expense0.50%0.70%0.72%0.73%0.71%Fee Waiver0.00%-0.45%-0.49%-0.65%-0.54%Net Expense0.50%0.61%0.63%0.58%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Email Address SBIO ETF News HeadlinesSBIO ETF: Betting On Medical BreakthroughsDecember 14, 2024 | seekingalpha.comAdvacam & Vector Space Biosciences sign Letter of Intent (LOI) to Develop AI Models & CubeSat Payloads for the Space IndustryOctober 10, 2024 | businesswire.comThe Trump Dump is starting; Get out of stocks now?The first 365 days of the Trump presidency… Will be the best time to get rich in American history.June 8, 2025 | Paradigm Press (Ad)Why Biotech ETFs Are Beating the MarketSeptember 7, 2024 | msn.comALPS Medical Breakthroughs ETF (^SBIO-IV)July 19, 2024 | finance.yahoo.comHow does spaceflight lead to medical breakthroughs? Veteran astronaut explainsMay 22, 2024 | msn.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $33.03 on January 1st, 2025. Since then, SBIO stock has decreased by 4.4% and is now trading at $31.58. View the best growth stocks for 2025 here. Who are ALPS Medical Breakthroughs ETF's major shareholders? ALPS Medical Breakthroughs ETF's top institutional shareholders include Phoenix Financial Ltd. (50.87%), DAVENPORT & Co LLC (25.98%), Jones Financial Companies Lllp (0.96%) and NTV Asset Management LLC (0.94%). How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AUO (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/31/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings104 Fund Statistics Assets Under Management$88.48 million Average Daily Volume$13.22 thousand Discount/Premium-0.02% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Portfolio Solutions Distributor, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableOptionable Options Volume1 Put Options8 Call Options1 Short Interest100 shs Miscellaneous Outstanding Shares2,830,000Beta0.77 Creation Unit50,000 Creation Fee$500.00 20 High-Yield Dividend Stocks that Could Ruin Your RetirementAlmost everyone loves strong dividend-paying stocks, but high yields can signal danger. Discover 20 high-yield dividend stocks paying an unsustainably large percentage of their earnings. Enter your email to get this report and avoid a high-yield dividend trap.Get This Free Report Top 10 SBIO HoldingsVerona Pharma (NASDAQ:VRNA)Holding Weight: 5.51%Alkermes (NASDAQ:ALKS)Holding Weight: 4.28%Axsome Therapeutics (NASDAQ:AXSM)Holding Weight: 4.12%Rhythm Pharmaceuticals (NASDAQ:RYTM)Holding Weight: 3.41%PTC Therapeutics (NASDAQ:PTCT)Holding Weight: 3.35%Avidity Biosciences (NASDAQ:RNA)Holding Weight: 3.34%ACADIA Pharmaceuticals (NASDAQ:ACAD)Holding Weight: 3.25%Akero Therapeutics (NASDAQ:AKRO)Holding Weight: 3.25%Merus (NASDAQ:MRUS)Holding Weight: 3.15%Zai Lab (NASDAQ:ZLAB)Holding Weight: 2.86%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 6/8/2025 by MarketBeat.com Staff From Our PartnersTrump’s Wealth Reset: Could You Be The First Beneficiary?Trump's Reset Can Give Birth To America's Greatest Era Yet A 90-Year cycle may end soon, creating real weal...American Hartford Gold | SponsoredGold is soaring. Here’s how to get paid from itGold just broke through $3,300… And while the headlines shout about price targets, something even more powe...Investors Alley | SponsoredElon’s NEXT Big IPO?Cancel your internet TODAY!? Take your latest internet bill and light it on fire… then count the seconds it...Banyan Hill Publishing | SponsoredThe Trump Dump is starting; Get out of stocks now?The first 365 days of the Trump presidency… Will be the best time to get rich in American history.Paradigm Press | SponsoredThe DOJ Just Paved the Way for Account SeizuresWashington is running out of money…And guess where they'll look next? When governments go broke, they take ...Priority Gold | SponsoredBanks aren’t ready for this altcoin—are you?I've never been more confident about a DeFi opportunity. This isn't about complex trading or risky bets. Th...Crypto 101 Media | SponsoredHow to target 627% gains from Trump’s tweetsPresident Trump is shaking up the market with his tweets and Truth Social posts... But while this chaos has...Monument Traders Alliance | SponsoredThe Age of Chaos has begunThis is one of the most confusing markets in history. We have entered an Age of Chaos. And you must take...Weiss Ratings | Sponsored Adding Choose a watchlist: Watchlist Adding You have already added five stocks to your watchlist. Upgrade to MarketBeat All Access to add more stocks to your watchlist. Adding ALPS Medical Breakthroughs ETF Please log in to your account or sign up in order to add this asset to your watchlist. Share ALPS Medical Breakthroughs ETF With A Colleague Link copied to clipboard. Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.