Deerfield Management Company, L.P. (Series C) Top Holdings and 13F Report (2025) About Deerfield Management Company, L.P. (Series C)Investment ActivityDeerfield Management Company, L.P. (Series C) has $5.06 billion in total holdings as of March 31, 2025.Deerfield Management Company, L.P. (Series C) owns shares of 123 different stocks, but just 28 companies or ETFs make up 80% of its holdings.Approximately 12.99% of the portfolio was purchased this quarter.About 9.75% of the portfolio was sold this quarter.This quarter, Deerfield Management Company, L.P. (Series C) has purchased 106 new stocks and bought additional shares in 20 stocks.Deerfield Management Company, L.P. (Series C) sold shares of 17 stocks and completely divested from 30 stocks this quarter.Largest Holdings Nuvalent $1,275,923,422Viatris $208,966,784INTEGRA LIFESCIENCES HLDGS C $170,982,036Neurocrine Biosciences $164,683,400Centene $162,212,324 Largest New Holdings this Quarter 91307C102 - United Therapeutics $84,843,919 Holding717081103 - Pfizer $84,820,481 Holding457669307 - Insmed $34,940,820 Holding92337R101 - Vera Therapeutics $25,221,000 Holding45258DAB1 - IMMUNOCORE HLDGS PLC $25,194,390 Holding Largest Purchases this Quarter United Therapeutics 275,226 shares (about $84.84M)Pfizer 3,347,296 shares (about $84.82M)Neurocrine Biosciences 627,000 shares (about $69.35M)Insmed 458,000 shares (about $34.94M)Vera Therapeutics 1,050,000 shares (about $25.22M) Largest Sales this Quarter Alignment Healthcare 2,736,829 shares (about $50.96M)BioCryst Pharmaceuticals 2,954,777 shares (about $22.16M)Embecta 550,000 shares (about $7.01M)Phreesia 261,988 shares (about $6.70M)DocGo 2,144,456 shares (about $5.66M) Sector Allocation Over TimeMap of 500 Largest Holdings ofDeerfield Management Company, L.P. (Series C) Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorNUVLNuvalent$1,275,923,4220.0%17,991,02425.2%MedicalVTRSViatris$208,966,784$38,690 ▼0.0%23,991,5944.1%MedicalINTEGRA LIFESCIENCES HLDGS C$170,982,0360.0%174,364,0003.4%NOTE 0.500% 8/1NBIXNeurocrine Biosciences$164,683,400$69,346,200 ▲72.7%1,489,0003.3%MedicalCNCCentene$162,212,3240.0%2,671,9213.2%MedicalOSCROscar Health$155,233,124$76,274 ▲0.0%11,840,8183.1%FinanceMRUSMerus$133,590,630$8,466,025 ▲6.8%3,173,9282.6%MedicalSPRYARS Pharmaceuticals$132,274,3850.0%10,514,6572.6%MedicalACCOLADE INC$130,625,3400.0%132,598,0002.6%NOTE 0.500% 4/0ALNYLAM PHARMACEUTICALS INC$126,865,3100.0%110,000,0002.5%NOTE 1.000% 9/1RVMDRevolution Medicines$117,300,860$2,086,240 ▲1.8%3,317,3322.3%MedicalMIRUM PHARMACEUTICALS INC$114,508,8000.0%70,000,0002.3%NOTE 4.000% 5/0AHCOAdaptHealth$105,271,6840.0%9,711,4102.1%MedicalINDVIndivior$100,705,035$16,048,520 ▲19.0%10,567,1602.0%MedicalBKDBrookdale Senior Living$97,732,7730.0%15,612,2641.9%MedicalALHCAlignment Healthcare$85,046,347$50,959,756 ▼-37.5%4,567,4731.7%MedicalUTHRUnited Therapeutics$84,843,919$84,843,919 ▲New Holding275,2261.7%MedicalPFEPfizer$84,820,481$84,820,481 ▲New Holding3,347,2961.7%MedicalNAMSNewAmsterdam Pharma$84,008,000$4,306,540 ▼-4.9%4,103,9571.7%MedicalCPRXCatalyst Pharmaceuticals$82,987,113$7,011,596 ▲9.2%3,422,1491.6%MedicalDVAXDynavax Technologies$67,333,664$30,220 ▼0.0%5,191,4931.3%MedicalBAXBaxter International$65,827,7130.0%1,923,1001.3%MedicalLEGNLegend Biotech$59,158,821$6,509,029 ▲12.4%1,743,5551.2%MedicalBIOBio-Rad Laboratories$55,061,609$18,127,196 ▲49.1%226,0701.1%MedicalIDYAIDEAYA Biosciences$53,522,485$8,706,805 ▲19.4%3,267,5511.1%MedicalEWTXEdgewise Therapeutics$45,727,1980.0%2,078,5090.9%MedicalLRMRLarimar Therapeutics$45,648,7440.0%21,231,9740.9%MedicalEHABEnhabit$43,930,187$116,257 ▼-0.3%4,997,7460.9%MedicalALNYAlnylam Pharmaceuticals$39,152,900$51,574 ▼-0.1%145,0000.8%MedicalBCRXBioCryst Pharmaceuticals$38,922,488$22,160,828 ▼-36.3%5,189,6650.8%MedicalIRONDisc Medicine$38,835,010$9,025,445 ▲30.3%782,3330.8%MedicalCNMDCONMED$36,898,290$58,216 ▼-0.2%611,0000.7%MedicalLANTHEUS HLDGS INC$35,581,2640.0%25,255,0000.7%NOTE 2.625%12/1NVSTEnvista$34,950,516$17,372,673 ▲98.8%2,024,9430.7%MedicalINSMInsmed$34,940,820$34,940,820 ▲New Holding458,0000.7%MedicalEMBCEmbecta$34,686,821$7,012,500 ▼-16.8%2,720,5350.7%MedicalCMRXChimerix$32,094,1200.0%3,771,3420.6%MedicalPHVSPharvaris$31,674,1850.0%2,017,4640.6%MedicalCGEMCullinan Therapeutics$29,226,551$3,644,501 ▲14.2%3,860,8390.6%MedicalINMDInMode$28,006,2800.0%1,578,7080.6%MedicalPHRPhreesia$25,811,613$6,696,413 ▼-20.6%1,009,8440.5%MedicalVERAVera Therapeutics$25,221,000$25,221,000 ▲New Holding1,050,0000.5%MedicalIMMUNOCORE HLDGS PLC$25,194,390$25,194,390 ▲New Holding30,000,0000.5%NOTE 2.500% 2/0LQDALiquidia$23,847,476$23,847,476 ▲New Holding1,616,7780.5%MedicalDAWNDay One Biopharmaceuticals$23,478,668$2,892,126 ▲14.0%2,960,7400.5%MedicalPRAXIS PRECISION MEDICINES I$23,476,787$23,476,787 ▲New Holding619,9310.5%COM NEWLNTHLantheus$23,445,2770.0%240,2180.5%MedicalSVRASavara$22,060,2800.0%7,964,0000.4%MedicalCG ONCOLOGY INC$20,833,521$21,992 ▼-0.1%850,6950.4%COMESTAEstablishment Labs$20,402,5000.0%500,0000.4%MedicalCERTCertara$20,023,898$20,023,898 ▲New Holding2,022,6160.4%MedicalXERIS BIOPHARMA HOLDINGS INC$19,934,828$19,934,828 ▲New Holding10,500,0000.4%NOTE 8.000% 7/1IARTIntegra LifeSciences$17,479,081$17,479,081 ▲New Holding794,8650.3%MedicalBEAMBeam Therapeutics$17,143,610$17,143,610 ▲New Holding877,8090.3%MedicalKYMRKymera Therapeutics$16,230,4100.0%593,0000.3%MedicalCOGTCogent Biosciences$15,776,833$17,143 ▲0.1%2,633,8620.3%MedicalMREOMereo BioPharma Group$15,098,4650.0%6,710,4290.3%MedicalCONCENTRA GROUP HOLDINGS PAR$14,105,0000.0%650,0000.3%COMMON STOCKMETSERA INC$13,610,000$13,610,000 ▲New Holding500,0000.3%COMDCGODocGo$13,335,960$5,661,364 ▼-29.8%5,051,5000.3%MedicalTXG10x Genomics$13,126,376$57,566 ▲0.4%1,503,5940.3%MedicalLUNGPulmonx$12,719,700$2,390,745 ▲23.1%1,890,0000.3%MedicalBETA BIONICS INC$12,435,840$12,435,840 ▲New Holding1,016,0000.2%COMZENAS BIOPHARMA INC$12,347,2420.0%1,562,9420.2%COMFHTXFoghorn Therapeutics$11,882,6260.0%3,255,5140.2%MedicalNVCRNovoCure$11,585,121$11,585,121 ▲New Holding650,1190.2%MedicalOPKOPKO Health$11,464,561$11,464,561 ▲New Holding6,906,3620.2%MedicalDCTHDelcath Systems$10,350,839$10,350,839 ▲New Holding813,1060.2%MedicalGHRSGH Research$10,202,750$10,202,750 ▲New Holding925,0000.2%MedicalRXSTRxSight$9,906,383$9,906,383 ▲New Holding392,3320.2%MedicalSLPSimulations Plus$8,682,262$8,682,262 ▲New Holding354,0890.2%Computer and TechnologyDYNE THERAPEUTICS INC$8,497,788$3,940,857 ▲86.5%812,4080.2%COMPCVXVaxcyte$8,496,0000.0%225,0000.2%MedicalSIONNA THERAPEUTICS INC$7,813,620$7,813,620 ▲New Holding747,0000.2%COMSPYRE THERAPEUTICS INC$7,260,7500.0%450,0000.1%COM NEWGPCRStructure Therapeutics$6,463,6750.0%373,4070.1%MedicalNPCENeuroPace$6,145,000$6,145,000 ▲New Holding500,0000.1%MedicalPERSPECTIVE THERAPEUTICS INC$6,026,650$232,896 ▼-3.7%2,829,4130.1%COM NEWNEUROGENE INC$5,232,965$14,813 ▼-0.3%446,8800.1%COMTOIOncology Institute$3,830,4590.0%3,360,0520.1%MedicalHLVXHilleVax$2,729,8480.0%1,882,6540.1%MedicalCALCCalciMedica$2,483,0000.0%1,300,0000.0%MedicalBIOMX INC$1,385,976$392,601 ▲39.5%2,494,1080.0%COM NEWALECAlector$1,297,886$14,477 ▼-1.1%1,055,1920.0%MedicalANNXAnnexon$1,126,9520.0%583,9130.0%MedicalTWSTTwist Bioscience$935,4480.0%23,8270.0%MedicalNAMSWNewAmsterdam Pharma$834,1550.0%92,7870.0%MedicalHUMHumana$242,6380.0%9170.0%MedicalJOESt. Joe$210,007$210,007 ▲New Holding4,4730.0%FinanceDXCDXC Technology$202,605$202,605 ▲New Holding11,8830.0%Computer and TechnologyXPOFXponential Fitness$192,398$192,398 ▲New Holding23,0970.0%Consumer DiscretionaryFPIFarmland Partners$188,022$188,022 ▲New Holding16,8630.0%FinanceHNRGHallador Energy$168,396$168,396 ▲New Holding13,7130.0%EnergyREIRing Energy$146,482$146,482 ▲New Holding127,3760.0%EnergyQSIAWQuantum-Si$133,3330.0%333,3330.0%MedicalMFAMFA Financial$112,193$112,193 ▲New Holding10,9350.0%FinanceWOOFPetco Health and Wellness$108,110$108,110 ▲New Holding35,4460.0%Retail/WholesaleBLZEBackblaze$103,724$103,724 ▲New Holding21,4750.0%Computer and TechnologyVIRVir Biotechnology$101,917$101,917 ▲New Holding15,7280.0%MedicalMAXMediaAlpha$99,746$99,746 ▲New Holding10,7950.0%Business ServicesShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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