Deerfield Management Company, L.P. (Series C) Top Holdings and 13F Report (2025) About Deerfield Management Company, L.P. (Series C)Investment ActivityDeerfield Management Company, L.P. (Series C) has $5.51 billion in total holdings as of June 30, 2025.Deerfield Management Company, L.P. (Series C) owns shares of 124 different stocks, but just 26 companies or ETFs make up 80% of its holdings.Approximately 11.78% of the portfolio was purchased this quarter.About 10.29% of the portfolio was sold this quarter.This quarter, Deerfield Management Company, L.P. (Series C) has purchased 123 new stocks and bought additional shares in 28 stocks.Deerfield Management Company, L.P. (Series C) sold shares of 13 stocks and completely divested from 44 stocks this quarter.Largest Holdings Nuvalent $1,372,715,131Oscar Health $249,767,231Viatris $214,533,490Merus $178,031,433Centene $172,901,884 Largest New Holdings this Quarter 58933Y105 - Merck & Co., Inc. $67,897,432 Holding875372AD6 - TANDEM DIABETES CARE INC $38,516,440 Holding60770K107 - Moderna $27,590,000 Holding53802LAB8 - LIVANOVA PLC $25,399,225 Holding92276F100 - Ventas $22,355,100 Holding Largest Purchases this Quarter United Therapeutics 265,400 shares (about $76.26M)Merck & Co., Inc. 857,724 shares (about $67.90M)Vera Therapeutics 2,298,117 shares (about $54.14M)Legend Biotech 1,218,783 shares (about $43.25M)TANDEM DIABETES CARE INC 40,000,000 shares (about $38.52M) Largest Sales this Quarter Alignment Healthcare 4,224,915 shares (about $59.15M)Neurocrine Biosciences 321,198 shares (about $40.37M)10x Genomics 1,492,293 shares (about $17.28M)ARS Pharmaceuticals 790,149 shares (about $13.79M)Catalyst Pharmaceuticals 542,673 shares (about $11.78M) Sector Allocation Over TimeMap of 500 Largest Holdings ofDeerfield Management Company, L.P. (Series C) Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorNUVLNuvalent$1,372,715,1310.0%17,991,02424.9%MedicalOSCROscar Health$249,767,231$4,099,907 ▼-1.6%11,649,5914.5%FinanceVTRSViatris$214,533,490$288,555 ▲0.1%24,023,9073.9%MedicalMRUSMerus$178,031,433$11,082,820 ▲6.6%3,384,6283.2%MedicalCNCCentene$172,901,884$27,870,012 ▲19.2%3,185,3703.1%MedicalINTEGRA LIFESCIENCES HLDGS C$172,859,5870.0%174,364,0003.1%NOTE 0.500% 8/1SPRYARS Pharmaceuticals$169,692,665$13,788,100 ▼-7.5%9,724,5083.1%MedicalINDVIndivior$155,759,9380.0%10,567,1602.8%MedicalUTHRUnited Therapeutics$155,348,881$76,262,690 ▲96.4%540,6262.8%MedicalNBIXNeurocrine Biosciences$146,781,033$40,371,377 ▼-21.6%1,167,8022.7%MedicalALNYLAM PHARMACEUTICALS INC$143,172,1500.0%110,000,0002.6%NOTE 1.000% 9/1RVMDRevolution Medicines$124,500,009$2,455,365 ▲2.0%3,384,0722.3%MedicalMIRUM PHARMACEUTICALS INC$124,213,1800.0%70,000,0002.3%NOTE 4.000% 5/0BKDBrookdale Senior Living$106,921,357$1,740,000 ▼-1.6%15,362,2641.9%MedicalLEGNLegend Biotech$105,133,376$43,254,609 ▲69.9%2,962,3381.9%MedicalPFEPfizer$104,383,839$23,245,384 ▲28.6%4,306,2641.9%MedicalAHCOAdaptHealth$93,403,160$1,824,564 ▲2.0%9,904,8951.7%MedicalNAMSNewAmsterdam Pharma$92,649,909$18,327,248 ▲24.7%5,115,9531.7%MedicalIDYAIDEAYA Biosciences$82,299,837$13,615,915 ▲19.8%3,915,3111.5%MedicalVERAVera Therapeutics$78,881,637$54,143,637 ▲218.9%3,348,1171.4%MedicalINSMInsmed$70,518,448$24,425,328 ▲53.0%700,7001.3%MedicalMRKMerck & Co., Inc.$67,897,432$67,897,432 ▲New Holding857,7241.2%MedicalCPRXCatalyst Pharmaceuticals$62,484,629$11,776,004 ▼-15.9%2,879,4761.1%MedicalLRMRLarimar Therapeutics$61,360,4050.0%21,231,9741.1%MedicalBAXBaxter International$58,231,4680.0%1,923,1001.1%MedicalBIOBio-Rad Laboratories$54,555,2120.0%226,0701.0%MedicalIRONDisc Medicine$48,691,583$7,259,227 ▲17.5%919,4030.9%MedicalALNYAlnylam Pharmaceuticals$47,283,0500.0%145,0000.9%MedicalEHABEnhabit$46,077,889$2,100,382 ▼-4.4%4,779,8640.8%MedicalCERTCertara$45,935,358$22,270,751 ▲94.1%3,926,0990.8%MedicalNVSTEnvista$43,297,611$3,730,225 ▲9.4%2,215,8450.8%MedicalBCRXBioCryst Pharmaceuticals$42,040,320$4,459,078 ▼-9.6%4,692,0000.8%MedicalTANDEM DIABETES CARE INC$38,516,440$38,516,440 ▲New Holding40,000,0000.7%NOTE 1.500% 3/1CNMDCONMED$36,470,114$4,649,234 ▲14.6%700,2710.7%MedicalPHVSPharvaris$35,507,3660.0%2,017,4640.6%MedicalLANTHEUS HLDGS INC$32,062,6870.0%25,255,0000.6%NOTE 2.625%12/1CGEMCullinan Therapeutics$29,032,307$39,811 ▼-0.1%3,855,5520.5%MedicalPRAXIS PRECISION MEDICINES I$28,885,449$2,817,350 ▲10.8%686,9310.5%COM NEWPHRPhreesia$28,874,861$134,701 ▲0.5%1,014,5770.5%MedicalKYMRKymera Therapeutics$28,496,920$2,618,400 ▲10.1%653,0000.5%MedicalMRNAModerna$27,590,000$27,590,000 ▲New Holding1,000,0000.5%MedicalEWTXEdgewise Therapeutics$27,102,565$146,688 ▼-0.5%2,067,3200.5%MedicalEMBCEmbecta$26,644,709$282,725 ▲1.1%2,749,7120.5%MedicalIMMUNOCORE HLDGS PLC$25,849,7400.0%30,000,0000.5%NOTE 2.500% 2/0LIVANOVA PLC$25,399,225$25,399,225 ▲New Holding25,000,0000.5%NOTE 2.500% 3/1DAWNDay One Biopharmaceuticals$24,200,352$4,955,542 ▲25.8%3,723,1310.4%MedicalVTRVentas$22,355,100$22,355,100 ▲New Holding354,0000.4%FinanceLQDALiquidia Technologies$20,145,0540.0%1,616,7780.4%MedicalCOGTCogent Biosciences$18,956,744$45,615 ▲0.2%2,640,2150.3%MedicalMREOMereo BioPharma Group$18,185,2630.0%6,710,4290.3%MedicalINSPInspire Medical Systems$18,167,800$18,167,800 ▲New Holding140,0000.3%MedicalSVRASavara$18,157,9200.0%7,964,0000.3%MedicalXERIS BIOPHARMA HOLDINGS INC$17,732,0750.0%10,500,0000.3%NOTE 8.000% 7/1BETA BIONICS INC$17,012,122$2,219,162 ▲15.0%1,168,4150.3%COMXENEXenon Pharmaceuticals$16,965,226$16,965,226 ▲New Holding542,0200.3%MedicalVCYTVeracyte$16,893,750$16,893,750 ▲New Holding625,0000.3%MedicalSIONNA THERAPEUTICS INC$16,839,737$3,879,287 ▲29.9%970,5900.3%COMNEONeoGenomics$15,701,880$15,701,880 ▲New Holding2,148,0000.3%MedicalFHTXFoghorn Therapeutics$15,300,9160.0%3,255,5140.3%MedicalZENAS BIOPHARMA INC$15,144,9080.0%1,562,9420.3%COMNVCRNovoCure$14,687,118$3,115,000 ▲26.9%825,1190.3%MedicalTSHATaysha Gene Therapies$12,441,660$12,441,660 ▲New Holding5,386,0000.2%MedicalRXSTRxSight$11,556,350$6,456,034 ▲126.6%888,9500.2%MedicalDCTHDelcath Systems$11,050,830$7,412 ▼-0.1%812,5610.2%MedicalOMADA HEALTH INC$10,121,858$10,121,858 ▲New Holding553,1070.2%COMIARTIntegra LifeSciences$9,752,9940.0%794,8650.2%MedicalSPYRE THERAPEUTICS INC$9,186,565$2,450,065 ▲36.4%613,6650.2%COM NEWDCGODocGo$7,758,257$172,598 ▼-2.2%4,941,5650.1%MedicalGPCRStructure Therapeutics$7,744,4610.0%373,4070.1%MedicalPCVXVaxcyte$7,314,7500.0%225,0000.1%MedicalTOIOncology Institute$6,888,1070.0%3,360,0520.1%MedicalSLPSimulations Plus$6,178,8530.0%354,0890.1%Computer and TechnologyNPCENeuroPace$5,570,0000.0%500,0000.1%MedicalJADE BIOSCIENCES INC$5,306,318$5,306,318 ▲New Holding531,1630.1%COM NEWLUNGPulmonx$4,895,1000.0%1,890,0000.1%MedicalALHCAlignment Healthcare$4,795,812$59,148,810 ▼-92.5%342,5580.1%MedicalHLVXHilleVax$3,746,4810.0%1,882,6540.1%MedicalCALCCalciMedica$2,080,0000.0%1,300,0000.0%MedicalALECAlector$1,477,2690.0%1,055,1920.0%MedicalANNXAnnexon$1,401,3910.0%583,9130.0%MedicalBIOMX INC$1,122,3490.0%2,494,1080.0%COM NEWTWSTTwist Bioscience$876,5950.0%23,8270.0%MedicalNAMSWNewAmsterdam Pharma$742,2960.0%92,7870.0%MedicalSHCSotera Health$503,091$503,091 ▲New Holding45,2420.0%MedicalCOOPER COS INC$450,300$450,300 ▲New Holding6,3280.0%COMTMOThermo Fisher Scientific$371,401$371,401 ▲New Holding9160.0%MedicalUFPTUFP Technologies$370,391$370,391 ▲New Holding1,5170.0%IndustrialsALGNAlign Technology$368,247$368,247 ▲New Holding1,9450.0%MedicalATRCAtriCure$364,992$364,992 ▲New Holding11,1380.0%MedicalLMATLeMaitre Vascular$346,235$346,235 ▲New Holding4,1690.0%MedicalKIDSOrthoPediatrics$332,639$332,639 ▲New Holding15,4860.0%MedicalENOVEnovis$321,973$321,973 ▲New Holding10,2670.0%MedicalNHCNational HealthCare$313,111$313,111 ▲New Holding2,9260.0%MedicalDVADaVita$299,287$299,287 ▲New Holding2,1010.0%MedicalBLFSBioLife Solutions$294,452$294,452 ▲New Holding13,6700.0%MedicalUHSUniversal Health Services$289,297$289,297 ▲New Holding1,5970.0%MedicalAMEDAmedisys$269,982$269,982 ▲New Holding2,7440.0%MedicalHAEHaemonetics$263,299$263,299 ▲New Holding3,5290.0%MedicalIQVIQVIA$255,769$255,769 ▲New Holding1,6230.0%MedicalMDXGMiMedx Group$240,435$240,435 ▲New Holding39,3510.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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