Deerfield Management Company, L.P. (Series C) Top Holdings and 13F Report (2026) About Deerfield Management Company, L.P. (Series C)Investment ActivityDeerfield Management Company, L.P. (Series C) has $8.48 billion in total holdings as of March 31, 2026.Deerfield Management Company, L.P. (Series C) owns shares of 82 different stocks, but just 31 companies or ETFs make up 80% of its holdings.Approximately 12.82% of the portfolio was purchased this quarter.About 7.87% of the portfolio was sold this quarter.This quarter, Deerfield Management Company, L.P. (Series C) has purchased 150 new stocks and bought additional shares in 15 stocks.Deerfield Management Company, L.P. (Series C) sold shares of 9 stocks and completely divested from 80 stocks this quarter.Largest Holdings Nuvalent $1,767,103,703BROOKDALE SR LIVING INC $505,441,129Cogent Biosciences $348,099,826PRAXIS PRECISION MEDICINES I $310,382,059Viatris $272,985,357 Largest New Holdings this Quarter 04280AAC4 - ARROWHEAD PHARMACEUTICALS IN $207,181,800 Holding45579U109 - INDIVIOR PHARMACEUTICALS INC $94,420,639 Holding87164F105 - Syndax Pharmaceuticals $88,298,464 Holding252828108 - DIANTHUS THERAPEUTICS INC $85,582,707 Holding717081103 - Pfizer $85,363,200 Holding Largest Purchases this Quarter ARROWHEAD PHARMACEUTICALS IN 200,000,000 shares (about $207.18M)INDIVIOR PHARMACEUTICALS INC 3,097,790 shares (about $94.42M)Syndax Pharmaceuticals 3,779,900 shares (about $88.30M)DIANTHUS THERAPEUTICS INC 1,019,813 shares (about $85.58M)Pfizer 3,040,000 shares (about $85.36M) Largest Sales this Quarter Neurocrine Biosciences 574,345 shares (about $75.66M)Revolution Medicines 597,613 shares (about $58.12M)Catalyst Pharmaceuticals 967,561 shares (about $23.96M)IDEAYA Biosciences 623,035 shares (about $20.76M)Centene 530,907 shares (about $17.38M) Sector Allocation Over TimeMap of 500 Largest Holdings ofDeerfield Management Company, L.P. (Series C) Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorNUVLNuvalent$1,767,103,7030.0%17,248,45020.8%MedicalBROOKDALE SR LIVING INC$505,441,1290.0%306,885,0006.0%NOTE 3.500%10/1COGTCogent Biosciences$348,099,8260.0%9,043,9034.1%MedicalPRAXIS PRECISION MEDICINES I$310,382,059$19,331,400 â–²6.6%963,3513.7%COM NEWVTRSViatris$272,985,3570.0%20,206,1703.2%MedicalUTHRUnited Therapeutics$270,991,860$18,386,531 â–²7.3%457,0003.2%MedicalRVMDRevolution Medicines$223,383,250$58,117,864 â–¼-20.6%2,297,0002.6%MedicalMIRUM PHARMACEUTICALS INC$209,440,2800.0%70,000,0002.5%NOTE 4.000% 5/0ARROWHEAD PHARMACEUTICALS IN$207,181,800$207,181,800 â–²New Holding200,000,0002.4%NOTE 1/1CELCCelcuity$195,635,9600.0%1,714,0002.3%MedicalCNCCentene$193,725,559$17,381,895 â–¼-8.2%5,917,0912.3%MedicalLRMRLarimar Therapeutics$160,231,383$22,500,000 â–²16.3%35,606,9741.9%MedicalBKDBrookdale Senior Living$159,194,5980.0%11,637,0321.9%MedicalVERAVera Therapeutics$149,740,083$13,581,447 â–¼-8.3%3,722,1001.8%MedicalIONSIonis Pharmaceuticals$148,653,3450.0%1,979,6691.8%MedicalBCRXBioCryst Pharmaceuticals$143,161,760$6,635,440 â–²4.9%15,038,0001.7%MedicalINSPInspire Medical Systems$139,433,016$61,760,138 â–²79.5%2,703,2381.6%MedicalLEGNLegend Biotech$139,069,371$31,759,491 â–²29.6%7,687,6381.6%MedicalAHCOAdaptHealth$136,584,9870.0%11,477,7301.6%MedicalNAMSNewAmsterdam Pharma$136,515,896$3,201,000 â–²2.4%4,264,7891.6%MedicalACHCAcadia Healthcare$105,722,8000.0%4,520,0001.2%MedicalARWRArrowhead Pharmaceuticals$98,645,722$16,279,992 â–¼-14.2%1,573,2971.2%MedicalCPRXCatalyst Pharmaceuticals$97,643,536$23,956,810 â–¼-19.7%3,943,6001.2%MedicalINDIVIOR PHARMACEUTICALS INC$94,420,639$94,420,639 â–²New Holding3,097,7901.1%COMXENEXenon Pharmaceuticals$93,952,722$62,434,259 â–²198.1%1,615,6961.1%MedicalIONIS PHARMACEUTICALS INC$90,613,8600.0%60,000,0001.1%NOTE 1.750% 6/1PHVSPharvaris$88,310,6870.0%3,126,0421.0%MedicalSNDXSyndax Pharmaceuticals$88,298,464$88,298,464 â–²New Holding3,779,9001.0%MedicalTNGXTango Therapeutics$86,751,328$25,938,018 â–²42.7%4,146,8131.0%MedicalALIGNMENT HEALTHCARE INC$85,858,7200.0%61,000,0001.0%NOTE 4.250%11/1DIANTHUS THERAPEUTICS INC$85,582,707$85,582,707 â–²New Holding1,019,8131.0%COMPFEPfizer$85,363,200$85,363,200 â–²New Holding3,040,0001.0%MedicalNBIXNeurocrine Biosciences$80,361,400$75,664,210 â–¼-48.5%610,0000.9%MedicalDAWNDay One Biopharmaceuticals$79,823,9290.0%3,723,1310.9%MedicalSVRASavara$74,086,7400.0%13,569,0000.9%MedicalZENAS BIOPHARMA INC$67,252,900$67,252,900 â–²New Holding65,000,0000.8%NOTE 2.500% 4/0EHABEnhabit$66,895,7410.0%4,747,7460.8%MedicalNEOGENOMICS INC$66,653,7780.0%72,689,0000.8%NOTE 0.250% 1/1GMABGenmab A/S$66,055,460$66,055,460 â–²New Holding2,462,0000.8%MedicalBIOBio-Rad Laboratories$63,017,0130.0%226,0700.7%MedicalLNTHLantheus$62,803,7240.0%827,9990.7%MedicalSPRYARS Pharmaceuticals$60,255,6100.0%7,503,8120.7%MedicalSTOKStoke Therapeutics$59,373,1600.0%1,823,5000.7%MedicalNVSTEnvista$56,070,237$1,785,997 â–¼-3.1%2,210,1000.7%MedicalIDYAIDEAYA Biosciences$50,979,867$20,759,526 â–¼-28.9%1,530,0080.6%MedicalBLTEBelite Bio$48,471,833$11,192,688 â–²30.0%304,0130.6%MedicalBMRNBioMarin Pharmaceutical$48,104,398$48,104,398 â–²New Holding851,5560.6%MedicalKYMRKymera Therapeutics$46,739,8490.0%561,1700.6%MedicalCERTCertara$44,509,0490.0%7,808,6050.5%MedicalBRIDGEBIO ONCOLOGY THERAPEUT$43,724,7420.0%4,885,4460.5%COM NEWIRONDisc Medicine$42,008,580$9,324,818 â–²28.5%657,0000.5%MedicalLIVANOVA PLC$40,033,2810.0%34,280,0000.5%NOTE 2.500% 3/1SIONNA THERAPEUTICS INC$38,910,9530.0%970,5900.5%COMCDNACareDx$38,035,7600.0%2,191,0000.4%MedicalGPCRStructure Therapeutics$37,017,2630.0%767,9930.4%MedicalIMMUNOCORE HLDGS PLC$27,025,2000.0%30,000,0000.3%NOTE 2.500% 2/0VCYTVeracyte$23,384,4600.0%726,0000.3%MedicalALNYAlnylam Pharmaceuticals$22,477,6530.0%67,9350.3%MedicalEMBCEmbecta$22,409,055$1,918,899 â–¼-7.9%2,534,9610.3%MedicalTYRATyra Biosciences$21,026,700$21,026,700 â–²New Holding549,0000.2%MedicalFHTXFoghorn Therapeutics$21,005,074$3,561,846 â–²20.4%4,394,3670.2%MedicalBRIGHT MINDS BIOSCIENCES INC$20,650,510$20,650,510 â–²New Holding283,0000.2%COM NEWCMPXCompass Therapeutics$19,075,7400.0%3,606,0000.2%MedicalMONOPAR THERAPEUTICS INC$17,737,989$8,393,116 â–²89.8%323,7450.2%COM NEWKYVERNA THERAPEUTICS INC$17,260,0000.0%2,000,0000.2%COMSPYGLASS PHARMA INC$14,250,500$14,250,500 â–²New Holding550,0000.2%COM SHSBETA BIONICS INC$13,266,480$3,864,634 â–²41.1%1,324,0000.2%COMTSHATaysha Gene Therapies$12,168,0780.0%2,722,1650.1%MedicalTOIOncology Institute$10,315,3600.0%3,360,0520.1%MedicalCGEMCullinan Therapeutics$5,487,4610.0%386,1690.1%MedicalANNXAnnexon$3,234,8780.0%583,9130.0%MedicalALECAlector$2,268,6630.0%1,055,1920.0%MedicalNAMSWNewAmsterdam Pharma$1,859,4510.0%92,7870.0%MedicalEWEdwards Lifesciences$1,097,2560.0%13,7020.0%MedicalBIOMX INC$492,795$8 â–²0.0%131,2720.0%COM NEWVERADERMICS INC$315,750$315,750 â–²New Holding5,0000.0%COMMON STOCKHUMHumana$158,9990.0%9170.0%MedicalTOIIWOncology Institute$54,7500.0%1,250,0000.0%MedicalQSIAWQuantum-Si$36,2000.0%333,3330.0%MedicalPMVPPMV Pharmaceuticals$10,9000.0%8,7900.0%MedicalSRZNWSurrozen$2,6670.0%166,6660.0%MedicalMYGNMyriad Genetics$2,2730.0%5050.0%MedicalINDVIndivior$0$121,743,100 â–¼-100.0%00.0%MedicalPHRPhreesia$0$33,823,841 â–¼-100.0%00.0%MedicalMRNAModerna$0$29,490,000 â–¼-100.0%00.0%MedicalLANTHEUS HLDGS INC$0$28,911,419 â–¼-100.0%00.0%NOTE 2.625%12/1VTRVentas$0$27,392,520 â–¼-100.0%00.0%FinanceSPYRE THERAPEUTICS INC$0$23,280,108 â–¼-100.0%00.0%COM NEWEWTXEdgewise Therapeutics$0$19,000,697 â–¼-100.0%00.0%MedicalCRMDCorMedix$0$12,885,389 â–¼-100.0%00.0%MedicalMEDLINE INC$0$10,920,000 â–¼-100.0%00.0%COM CL AOMADA HEALTH INC$0$8,728,028 â–¼-100.0%00.0%COMCALCCalciMedica$0$8,567,000 â–¼-100.0%00.0%MedicalPBHPrestige Consumer Healthcare$0$4,297,881 â–¼-100.0%00.0%MedicalVEEVVeeva Systems$0$3,953,627 â–¼-100.0%00.0%MedicalRDNTRadNet$0$3,564,004 â–¼-100.0%00.0%MedicalLABCORP HOLDINGS INC$0$3,468,416 â–¼-100.0%00.0%COM SHSENOVEnovis$0$3,390,473 â–¼-100.0%00.0%MedicalALHCAlignment Healthcare$0$3,245,814 â–¼-100.0%00.0%MedicalDGXQuest Diagnostics$0$3,191,564 â–¼-100.0%00.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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