Deerfield Management Company, L.P. (Series C) Top Holdings and 13F Report (2026) About Deerfield Management Company, L.P. (Series C)Investment ActivityDeerfield Management Company, L.P. (Series C) has $9.59 billion in total holdings as of June 30, 2026.Deerfield Management Company, L.P. (Series C) owns shares of 82 different stocks, but just 29 companies or ETFs make up 80% of its holdings.Approximately 10.23% of the portfolio was purchased this quarter.About 11.74% of the portfolio was sold this quarter.This quarter, Deerfield Management Company, L.P. (Series C) has purchased 82 new stocks and bought additional shares in 14 stocks.Deerfield Management Company, L.P. (Series C) sold shares of 12 stocks and completely divested from 13 stocks this quarter.Largest Holdings Nuvalent $2,130,183,575BROOKDALE SR LIVING INC $585,704,753Revolution Medicines $447,973,760PRAXIS PRECISION MEDICINES I $322,520,281Viatris $320,873,980 Largest New Holdings this Quarter 76155XAA8 - REVOLUTION MEDICINES INC $251,681,000 Holding15102KAB6 - CELCUITY INC $113,779,900 Holding603170101 - Mineralys Therapeutics $106,786,840 Holding101137107 - Boston Scientific $56,124,200 Holding698955101 - PARABILIS MEDICINES INC $51,474,868 Holding Largest Purchases this Quarter REVOLUTION MEDICINES INC 200,000,000 shares (about $251.68M)Genmab A/S 4,403,000 shares (about $120.95M)CELCUITY INC 100,000,000 shares (about $113.78M)Mineralys Therapeutics 3,958,000 shares (about $106.79M)Boston Scientific 1,315,000 shares (about $56.12M) Largest Sales this Quarter Cogent Biosciences 4,037,799 shares (about $156.26M)Centene 1,016,091 shares (about $65.22M)Inspire Medical Systems 1,406,376 shares (about $62.74M)INDIVIOR PHARMACEUTICALS INC 1,448,895 shares (about $59.45M)NEOGENOMICS INC 59,649,000 shares (about $55.82M) Sector Allocation Over TimeMap of 500 Largest Holdings ofDeerfield Management Company, L.P. (Series C) Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorNUVLNuvalent$2,130,183,5750.0%17,248,45022.2%HealthcareBROOKDALE SR LIVING INC$585,704,7530.0%306,885,0006.1%NOTE 3.500%10/1RVMDRevolution Medicines$447,973,760$17,791,600 â–²4.1%2,392,0004.7%HealthcarePRAXIS PRECISION MEDICINES I$322,520,2810.0%963,3513.4%COM NEWVTRSViatris$320,873,9800.0%20,206,1703.3%HealthcareCNCCentene$314,595,190$65,222,881 â–¼-17.2%4,901,0003.3%HealthcareREVOLUTION MEDICINES INC$251,681,000$251,681,000 â–²New Holding200,000,0002.6%NOTE 0.500% 5/0UTHRUnited Therapeutics$247,616,3100.0%457,0002.6%HealthcareARROWHEAD PHARMACEUTICALS IN$240,537,6000.0%200,000,0002.5%NOTE 1/1LEGNLegend Biotech$235,014,985$12,996,000 â–²5.9%8,137,6382.5%HealthcareCOGTCogent Biosciences$193,736,225$156,262,821 â–¼-44.6%5,006,1042.0%HealthcareGMABGenmab A/S$188,581,550$120,950,410 â–²178.8%6,865,0002.0%HealthcareBKDBrookdale Senior Living$187,239,8450.0%11,637,0322.0%HealthcareVERAVera Therapeutics$168,052,724$8,337,413 â–²5.2%3,916,4001.8%HealthcareIONSIonis Pharmaceuticals$156,967,9550.0%1,979,6691.6%HealthcareCELCCelcuity$151,805,085$27,513,595 â–¼-15.3%1,451,0141.6%HealthcareBCRXBioCryst Pharmaceuticals$150,964,030$584,030 â–²0.4%15,096,4031.6%HealthcareNAMSNewAmsterdam Pharma$144,533,6990.0%4,264,7891.5%HealthcareACHCAcadia Healthcare$133,475,6000.0%4,520,0001.4%HealthcareTNGXTango Therapeutics$130,998,500$1,369,125 â–²1.1%4,190,6111.4%HealthcareAHCOAdaptHealth$119,597,9470.0%11,477,7301.2%HealthcarePHVSPharvaris$116,743,532$8,645,000 â–²8.0%3,376,0421.2%HealthcareCELCUITY INC$113,779,900$113,779,900 â–²New Holding100,000,0001.2%NOTE 0.250% 8/0ARWRArrowhead Pharmaceuticals$113,221,873$15,017,565 â–¼-11.7%1,389,0551.2%HealthcareDIANTHUS THERAPEUTICS INC$109,695,511$10,284,140 â–²10.3%1,125,3131.1%COMLRMRLarimar Therapeutics$108,601,2710.0%35,606,9741.1%HealthcareMLYSMineralys Therapeutics$106,786,840$106,786,840 â–²New Holding3,958,0001.1%HealthcareALIGNMENT HEALTHCARE INC$103,829,9300.0%61,000,0001.1%NOTE 4.250%11/1IDYAIDEAYA Biosciences$101,169,527$44,146,129 â–²77.4%2,714,5031.1%HealthcareXENEXenon Pharmaceuticals$97,523,4110.0%1,615,6961.0%HealthcareIONIS PHARMACEUTICALS INC$93,104,4000.0%60,000,0001.0%NOTE 1.750% 6/1SVRASavara$83,585,0400.0%13,569,0000.9%HealthcareLNTHLantheus$83,537,709$8,320,500 â–¼-9.1%752,9990.9%HealthcareSNDXSyndax Pharmaceuticals$82,628,6140.0%3,779,9000.9%HealthcareZENAS BIOPHARMA INC$80,316,096$2,629,396 â–²3.4%67,200,0000.8%NOTE 2.500% 4/0BMRNBioMarin Pharmaceutical$76,264,876$27,538,842 â–²56.5%1,332,8360.8%HealthcarePFEPfizer$73,203,2000.0%3,040,0000.8%HealthcareINDIVIOR PHARMACEUTICALS INC$67,654,162$59,448,162 â–¼-46.8%1,648,8950.7%COMBIOBio-Rad Laboratories$66,376,4130.0%226,0700.7%HealthcareSPRYARS Pharmaceuticals$60,105,5340.0%7,503,8120.6%HealthcareSTOKStoke Therapeutics$59,664,9200.0%1,823,5000.6%HealthcareGPCRStructure Therapeutics$58,285,620$17,067,436 â–²41.4%1,086,0000.6%HealthcareNVSTEnvista$58,236,1350.0%2,210,1000.6%HealthcareINSPInspire Medical Systems$57,853,014$62,738,434 â–¼-52.0%1,296,8620.6%HealthcareCDNACareDx$56,932,113$5,511,387 â–¼-8.8%1,997,6180.6%HealthcareBSXBoston Scientific$56,124,200$56,124,200 â–²New Holding1,315,0000.6%HealthcareBLTEBelite Bio$55,003,288$8,189,846 â–²17.5%357,1990.6%HealthcarePARABILIS MEDICINES INC$51,474,868$51,474,868 â–²New Holding1,880,7040.5%COMCERTCertara$49,209,678$1,936,684 â–¼-3.8%7,512,9280.5%HealthcareIRONDisc Medicine$48,052,9800.0%657,0000.5%HealthcareLIVANOVA PLC$46,485,1200.0%34,280,0000.5%NOTE 2.500% 3/1BRIDGEBIO ONCOLOGY THERAPEUT$37,227,0990.0%4,885,4460.4%COM NEWTYRATyra Biosciences$32,482,980$14,947,920 â–²85.2%1,017,0000.3%HealthcareMONOPAR THERAPEUTICS INC$29,975,5500.0%323,7450.3%COM NEWSIONNA THERAPEUTICS INC$29,953,495$12,742,759 â–¼-29.8%680,9160.3%COMIMMUNOCORE HLDGS PLC$27,104,3400.0%30,000,0000.3%NOTE 2.500% 2/0AVALYN PHARMACEUTICALS INC$24,064,520$24,064,520 â–²New Holding731,0000.3%COM SHSFHTXFoghorn Therapeutics$21,444,5110.0%4,394,3670.2%HealthcareBETA BIONICS INC$20,747,0800.0%1,324,0000.2%COMALNYAlnylam Pharmaceuticals$20,450,4730.0%67,9350.2%HealthcareBRIGHT MINDS BIOSCIENCES INC$19,866,6000.0%283,0000.2%COM NEWODYSSEY THERAPEUTICS INC$19,573,261$19,573,261 â–²New Holding1,046,1390.2%COMMON STOCKTOIOncology Institute$18,245,0820.0%3,360,0520.2%HealthcareKYVERNA THERAPEUTICS INC$17,820,0000.0%2,000,0000.2%COMALAMAR BIOSCIENCES INC$16,254,000$16,254,000 â–²New Holding600,0000.2%COMMON STOCKCHEChemed$13,972,200$13,972,200 â–²New Holding30,0000.1%HealthcareSPYGLASS PHARMA INC$12,243,0000.0%550,0000.1%COM SHSNEOGENOMICS INC$12,202,076$55,816,076 â–¼-82.1%13,040,0000.1%NOTE 0.250% 1/1ADAGAdagene$11,199,997$11,199,997 â–²New Holding2,666,6660.1%HealthcareHEMAB THERAPEUTICS HLDGS INC$10,100,750$10,100,750 â–²New Holding275,0000.1%COM SHSMOBIA MED INC$8,988,077$8,988,077 â–²New Holding670,7520.1%COMMON STOCKEMBCEmbecta$8,263,9730.0%2,534,9610.1%HealthcareVCYTVeracyte$5,931,730$36,706,250 â–¼-86.1%101,0000.1%HealthcareANNXAnnexon$3,334,1430.0%583,9130.0%HealthcareALECAlector$2,120,9360.0%1,055,1920.0%HealthcareNAMSWNewAmsterdam Pharma$1,982,8580.0%92,7870.0%HealthcareEWEdwards Lifesciences$1,239,4830.0%13,7020.0%HealthcareMIRMMirum Pharmaceuticals$705,581$705,581 â–²New Holding6,0270.0%HealthcareHUMHumana$364,2510.0%9170.0%HealthcareTOIIWOncology Institute$51,0000.0%1,250,0000.0%HealthcarePMVPPMV Pharmaceuticals$11,7790.0%8,7900.0%HealthcareSRZNWSurrozen$2,7500.0%166,6660.0%HealthcareMIRUM PHARMACEUTICALS INC$0$209,440,280 â–¼-100.0%00.0%NOTE 4.000% 5/0CPRXCatalyst Pharmaceuticals$0$97,643,536 â–¼-100.0%00.0%HealthcareNBIXNeurocrine Biosciences$0$80,361,400 â–¼-100.0%00.0%HealthcareDAWNDay One Biopharmaceuticals$0$79,823,929 â–¼-100.0%00.0%HealthcareEHABEnhabit$0$66,895,741 â–¼-100.0%00.0%HealthcareKYMRKymera Therapeutics$0$46,739,849 â–¼-100.0%00.0%HealthcareCMPXCompass Therapeutics$0$19,075,740 â–¼-100.0%00.0%HealthcareTSHATaysha Gene Therapies$0$12,168,078 â–¼-100.0%00.0%HealthcareCGEMCullinan Therapeutics$0$5,487,461 â–¼-100.0%00.0%HealthcareBIOMX INC$0$492,795 â–¼-100.0%00.0%COM NEWVERADERMICS INC$0$315,750 â–¼-100.0%00.0%COMMON STOCKQSIAWQuantum-Si$0$36,200 â–¼-100.0%00.0%HealthcareMYGNMyriad Genetics$0$2,273 â–¼-100.0%00.0%HealthcareShowing largest 100 holdings. 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