Sio Capital Management, LLC Top Holdings and 13F Report (2026) About Sio Capital Management, LLCInvestment ActivitySio Capital Management, LLC has $697.31 million in total holdings as of March 31, 2026.Sio Capital Management, LLC owns shares of 76 different stocks, but just 29 companies or ETFs make up 80% of its holdings.Approximately 50.37% of the portfolio was purchased this quarter.About 40.60% of the portfolio was sold this quarter.This quarter, Sio Capital Management, LLC has purchased 68 new stocks and bought additional shares in 24 stocks.Sio Capital Management, LLC sold shares of 16 stocks and completely divested from 15 stocks this quarter.Largest Holdings Maximus $49,281,683WAYSTAR HLDG CORP $39,594,310Icon $33,901,576Cencora $31,694,841DIANTHUS THERAPEUTICS INC $31,054,176 Largest New Holdings this Quarter 218352102 - Corcept Therapeutics $27,199,535 Holding37733W204 - GSK $21,296,662 Holding002824100 - Abbott Laboratories $19,155,553 Holding29082K105 - Embecta $16,334,994 Holding829401108 - SIONNA THERAPEUTICS INC $11,800,091 Holding Largest Purchases this Quarter Corcept Therapeutics 674,759 shares (about $27.20M)Cencora 84,994 shares (about $26.70M)WAYSTAR HLDG CORP 1,028,511 shares (about $24.80M)GSK 385,879 shares (about $21.30M)Icon 179,156 shares (about $19.83M) Largest Sales this Quarter Sanofi 732,015 shares (about $35.27M)Celcuity 283,224 shares (about $32.33M)Zimmer Biomet 323,029 shares (about $29.21M)Organon & Co. 2,555,857 shares (about $15.31M)DIANTHUS THERAPEUTICS INC 104,458 shares (about $8.77M) Sector Allocation Over TimeMap of 500 Largest Holdings ofSio Capital Management, LLC Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorMMSMaximus$49,281,683$17,212,196 â–²53.7%768,8257.1%Business ServicesWAYSTAR HLDG CORP$39,594,310$24,797,400 â–²167.6%1,642,2365.7%COMICLRIcon$33,901,576$19,825,403 â–²140.8%306,3584.9%MedicalCORCencora$31,694,841$26,700,015 â–²534.6%100,8944.5%MedicalDIANTHUS THERAPEUTICS INC$31,054,176$8,766,115 â–¼-22.0%370,0454.5%COMANTERIS TECHNOLOGIES GLOBAL$29,875,456$19,471,198 â–²187.1%5,382,9654.3%COMCORTCorcept Therapeutics$27,199,535$27,199,535 â–²New Holding674,7593.9%MedicalLIVNLivaNova$26,797,849$6,307,249 â–²30.8%421,6153.8%MedicalTYRATyra Biosciences$23,188,314$3,042,437 â–²15.1%605,4393.3%MedicalCELCCelcuity$22,125,240$32,327,187 â–¼-59.4%193,8433.2%MedicalGSKGSK$21,296,662$21,296,662 â–²New Holding385,8793.1%MedicalANIPANI Pharmaceuticals$20,420,257$13,709,040 â–²204.3%265,5432.9%MedicalABTAbbott Laboratories$19,155,553$19,155,553 â–²New Holding186,5742.7%MedicalEMBCEmbecta$16,334,994$16,334,994 â–²New Holding1,847,8502.3%MedicalABIVAX SA$15,121,330$10,319,473 â–²214.9%135,8002.2%SPONSORED ADSVIRVir Biotechnology$13,427,635$9,141,682 â–²213.3%1,498,6201.9%MedicalHAEHaemonetics$12,437,074$7,216,391 â–²138.2%220,6721.8%MedicalSIONNA THERAPEUTICS INC$11,800,091$11,800,091 â–²New Holding294,3401.7%COMSNYSanofi$11,547,349$35,268,483 â–¼-75.3%239,6711.7%MedicalRAPPORT THERAPEUTICS INC$11,477,454$5,680,512 â–²98.0%366,8091.6%COMTFXTeleflex$11,339,028$947,790 â–²9.1%94,8001.6%MedicalBMRNBioMarin Pharmaceutical$10,971,827$2,172,718 â–¼-16.5%194,2261.6%MedicalCCRNCross Country Healthcare$10,324,894$277,977 â–²2.8%1,098,3931.5%Business ServicesTARAProtara Therapeutics$10,262,861$1,325,658 â–²14.8%1,969,8391.5%MedicalGPCRStructure Therapeutics$10,078,283$365,983 â–²3.8%209,0931.4%MedicalBHVNBiohaven$9,846,814$683,889 â–¼-6.5%1,163,9261.4%MedicalMONOPAR THERAPEUTICS INC$9,506,394$9,506,394 â–²New Holding173,5061.4%COM NEWEYPTEyepoint Pharmaceuticals$9,303,809$9,303,809 â–²New Holding721,7851.3%MedicalCRNXCrinetics Pharmaceuticals$9,075,896$4,541,671 â–²100.2%249,8871.3%MedicalEWTXEdgewise Therapeutics$8,473,059$992,408 â–²13.3%268,9861.2%MedicalCMPSCompass Pathways$8,331,083$8,331,083 â–²New Holding1,506,5251.2%MedicalOCULOcular Therapeutix$8,204,017$8,204,017 â–²New Holding968,5971.2%MedicalAQSTAquestive Therapeutics$7,979,981$3,858,637 â–²93.6%1,922,8871.1%MedicalRLMDRelmada Therapeutics$6,716,400$6,716,400 â–²New Holding965,0001.0%MedicalORUKA THERAPEUTICS INC$6,498,929$704,849 â–²12.2%132,4960.9%COMZENAS BIOPHARMA INC$6,485,322$6,485,322 â–²New Holding331,7300.9%COMBRIGHT MINDS BIOSCIENCES INC$6,281,477$306,474 â–²5.1%86,0830.9%COM NEWQDELQuidelOrtho$5,898,551$5,898,551 â–²New Holding359,0110.8%MedicalZBHZimmer Biomet$5,661,467$29,208,280 â–¼-83.8%62,6130.8%MedicalREPLReplimune Group$5,508,275$5,508,275 â–²New Holding720,0360.8%MedicalOGNOrganon & Co.$5,186,789$15,309,584 â–¼-74.7%865,9080.7%MedicalONKURE THERAPEUTICS INC$4,466,915$4,466,915 â–²New Holding1,078,9650.6%COM CL AIRONDisc Medicine$4,169,080$487,031 â–²13.2%65,2030.6%MedicalPMVPPMV Pharmaceuticals$3,814,959$545,640 â–²16.7%3,076,5800.5%MedicalIMNMImmunome$3,610,956$3,610,956 â–²New Holding165,1100.5%MedicalIARTIntegra LifeSciences$3,609,179$3,609,179 â–²New Holding383,1400.5%MedicalSVRASavara$3,351,8280.0%613,8880.5%MedicalCNCCentene$3,274,000$5,708,219 â–¼-63.6%100,0000.5%MedicalPRQRProQR Therapeutics$3,166,638$339,335 â–¼-9.7%1,954,7150.5%MedicalSHOULDER INNOVATIONS INC$3,060,614$251,805 â–¼-7.6%210,6410.4%COMMON STOCKOVIDOvid Therapeutics$2,780,286$388,753 â–¼-12.3%1,252,3810.4%MedicalKYMRKymera Therapeutics$2,684,8530.0%32,2350.4%MedicalALIGOS THERAPEUTICS INC$2,431,371$64,641 â–¼-2.6%327,2370.3%COM NEWCNTXContext Therapeutics$2,404,956$1,110,131 â–¼-31.6%917,9220.3%MedicalAN2 THERAPEUTICS INC$2,247,624$2,247,624 â–²New Holding657,2000.3%COMSERINA THERAPEUTICS INC$1,940,000$1,940,000 â–²New Holding1,000,0000.3%COM SHSIBIO INC$1,718,109$312,109 â–²22.2%904,2680.2%COM NEWADAGIO MED HLDGS INC$1,481,7300.0%1,288,4610.2%COMXILIO THERAPEUTICS INC$1,282,222$1,282,222 â–²New Holding152,4640.2%COMBRIDGEBIO ONCOLOGY THERAPEUT$1,169,1210.0%130,6280.2%COM NEWHYPRHyperfine$1,080,000$1,080,000 â–¼-50.0%1,000,0000.2%MedicalSENSEONICS HLDGS INC$771,1210.0%115,7840.1%COMFHTXFoghorn Therapeutics$587,4090.0%122,8890.1%MedicalTERNTerns Pharmaceuticals$532,4720.0%10,1000.1%MedicalENTAEnanta Pharmaceuticals$505,2000.0%40,0000.1%MedicalTELATELA Bio$394,5060.0%636,3000.1%MedicalNMTCNeuroOne Medical Technologies$385,621$499,621 â–¼-56.4%496,6140.1%MedicalBOUNDLESS BIO INC$180,0470.0%163,6790.0%COMNYXHNyxoah$148,4500.0%50,8390.0%MedicalMODULAR MED INC$138,283$138,283 â–²New Holding26,1900.0%COM NEWELTXElicio Therapeutics$125,073$3,048,788 â–¼-96.1%11,7000.0%MedicalERASErasca$80,900$80,900 â–²New Holding5,0000.0%MedicalOSCROscar Health$34,410$34,410 â–²New Holding3,0000.0%FinanceRCKTWRocket Pharmaceuticals$7,0200.0%400,0000.0%MedicalHUMAWHumacyte$4,5720.0%49,9980.0%MedicalSLPSimulations Plus$2,364$2,364 â–²New Holding2000.0%Computer and TechnologyCICigna Group$0$47,395,432 â–¼-100.0%00.0%MedicalRYTMRhythm Pharmaceuticals$0$28,440,528 â–¼-100.0%00.0%MedicalKVUEKenvue$0$25,278,875 â–¼-100.0%00.0%Consumer StaplesBRIGHTSPRING HEALTH SVCS INC$0$11,534,975 â–¼-100.0%00.0%COMCRLCharles River Laboratories International$0$10,968,408 â–¼-100.0%00.0%MedicalMCKMcKesson$0$5,249,856 â–¼-100.0%00.0%MedicalFULCFulcrum Therapeutics$0$4,320,420 â–¼-100.0%00.0%MedicalVTYXVentyx Biosciences$0$3,501,392 â–¼-100.0%00.0%MedicalALKSAlkermes$0$2,667,977 â–¼-100.0%00.0%MedicalIDYAIDEAYA Biosciences$0$2,617,986 â–¼-100.0%00.0%MedicalOUTLOOK THERAPEUTICS INC$0$1,778,132 â–¼-100.0%00.0%COMXLOXilio Therapeutics$0$1,366,531 â–¼-100.0%00.0%MedicalAVALO THERAPEUTICS INC$0$1,310,662 â–¼-100.0%00.0%COM NEWMODDModular Medical$0$286,119 â–¼-100.0%00.0%MedicalNEXTCURE INC$0$155,239 â–¼-100.0%00.0%COM NEWShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. 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