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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:AKBA NASDAQ:MRNS NASDAQ:PBYI NASDAQ:URGN On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAKBAAkebia Therapeutics$2.96+5.7%$3.38$1.24▼$4.08$784.83M1.024.11 million shs3.13 million shsMRNSMarinus Pharmaceuticals$0.55-0.2%$0.55$0.22▼$1.97$30.32M1.031.94 million shs260 shsPBYIPuma Biotechnology$4.52+4.1%$4.25$2.32▼$6.07$227.68M1.38483,423 shs315,682 shsURGNUrogen Pharma$18.87+4.3%$18.46$3.42▼$21.71$872.93M1.11.52 million shs767,447 shsThese 7 Stocks Will Be Magnificent in 2025Discover the next wave of investment opportunities with our report, 7 Stocks That Will Be Magnificent in 2025. Explore companies poised to replicate the growth, innovation, and value creation of the tech giants dominating today's markets.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAKBAAkebia Therapeutics-1.06%-4.44%-9.97%-21.35%+104.38%MRNSMarinus Pharmaceuticals0.00%0.00%0.00%0.00%-64.57%PBYIPuma Biotechnology-3.98%-4.41%-13.37%+27.65%+66.92%URGNUrogen Pharma+0.17%-5.29%-6.70%+21.72%+40.97%Compare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAKBAAkebia Therapeutics$2.96+5.7%$3.38$1.24▼$4.08$784.83M1.024.11 million shs3.13 million shsMRNSMarinus Pharmaceuticals$0.55-0.2%$0.55$0.22▼$1.97$30.32M1.031.94 million shs260 shsPBYIPuma Biotechnology$4.52+4.1%$4.25$2.32▼$6.07$227.68M1.38483,423 shs315,682 shsURGNUrogen Pharma$18.87+4.3%$18.46$3.42▼$21.71$872.93M1.11.52 million shs767,447 shsThese 7 Stocks Will Be Magnificent in 2025Discover the next wave of investment opportunities with our report, 7 Stocks That Will Be Magnificent in 2025. Explore companies poised to replicate the growth, innovation, and value creation of the tech giants dominating today's markets.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAKBAAkebia Therapeutics-1.06%-4.44%-9.97%-21.35%+104.38%MRNSMarinus Pharmaceuticals0.00%0.00%0.00%0.00%-64.57%PBYIPuma Biotechnology-3.98%-4.41%-13.37%+27.65%+66.92%URGNUrogen Pharma+0.17%-5.29%-6.70%+21.72%+40.97%Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceAKBAAkebia Therapeutics 3.00Buy$6.75128.04% UpsideMRNSMarinus Pharmaceuticals 2.44Hold$3.92613.29% UpsidePBYIPuma Biotechnology 3.00Buy$7.0054.87% UpsideURGNUrogen Pharma 3.00Buy$32.0069.58% UpsideCurrent Analyst Ratings BreakdownLatest AKBA, URGN, PBYI, and MRNS Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails8/18/2025URGNUrogen PharmaPiper SandlerSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageOverweight$36.008/13/2025AKBAAkebia TherapeuticsZacks ResearchSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingDowngradeStrong-Buy ➝ Hold8/11/2025URGNUrogen PharmaHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetBuy$50.00 ➝ $40.008/5/2025URGNUrogen PharmaD. Boral CapitalSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$25.007/8/2025URGNUrogen PharmaHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$50.007/7/2025URGNUrogen PharmaD. Boral CapitalSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$25.00(Data available from 9/18/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookAKBAAkebia Therapeutics$203.73M3.85N/AN/A($0.23) per share-12.87MRNSMarinus Pharmaceuticals$30.99M0.98N/AN/A$0.31 per share1.77PBYIPuma Biotechnology$238.06M0.96$0.85 per share5.30$1.88 per share2.40URGNUrogen Pharma$90.40M9.66N/AN/A($0.21) per share-89.86Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateAKBAAkebia Therapeutics-$69.41M-$0.17N/AN/AN/A-17.91%N/A-13.47%11/6/2025 (Estimated)MRNSMarinus Pharmaceuticals-$141.40M-$2.47N/AN/AN/A-446.48%-7,831.35%-120.74%N/APBYIPuma Biotechnology$30.28M$0.984.6111.89N/A20.38%53.15%23.51%11/6/2025 (Estimated)URGNUrogen Pharma-$126.87M-$3.32N/AN/AN/A-164.44%-97,487.15%-59.38%11/5/2025 (Estimated)Latest AKBA, URGN, PBYI, and MRNS EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/7/2025Q2 2025URGNUrogen Pharma-$0.82-$1.05-$0.23-$1.05$23.06 million$24.22 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthAKBAAkebia TherapeuticsN/AN/AN/AN/AN/AMRNSMarinus PharmaceuticalsN/AN/AN/AN/AN/APBYIPuma BiotechnologyN/AN/AN/AN/AN/AURGNUrogen PharmaN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioAKBAAkebia Therapeutics1.611.981.84MRNSMarinus PharmaceuticalsN/A1.661.47PBYIPuma Biotechnology0.101.731.62URGNUrogen PharmaN/A4.143.99Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipAKBAAkebia Therapeutics33.92%MRNSMarinus Pharmaceuticals98.80%PBYIPuma Biotechnology61.29%URGNUrogen Pharma91.29%Insider OwnershipCompanyInsider OwnershipAKBAAkebia Therapeutics3.00%MRNSMarinus Pharmaceuticals5.46%PBYIPuma Biotechnology23.30%URGNUrogen Pharma4.70%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableAKBAAkebia Therapeutics430265.15 million257.19 millionOptionableMRNSMarinus Pharmaceuticals11055.22 million52.20 millionOptionablePBYIPuma Biotechnology20050.37 million38.64 millionOptionableURGNUrogen Pharma20046.26 million44.09 millionOptionableAKBA, URGN, PBYI, and MRNS HeadlinesRecent News About These CompaniesUrogen Pharma $URGN Shares Purchased by UBS AM A Distinct Business Unit of UBS Asset Management Americas LLCSeptember 16 at 3:06 AM | marketbeat.comUrogen Pharma (NASDAQ:URGN) Raised to Hold at Wall Street ZenSeptember 15 at 2:07 AM | marketbeat.comUrogen Pharma (NASDAQ:URGN) Upgraded by Wall Street Zen to "Hold" RatingSeptember 14, 2025 | americanbankingnews.comTrexquant Investment LP Sells 157,097 Shares of Urogen Pharma $URGNSeptember 13, 2025 | marketbeat.comUrogen Pharma (NASDAQ:URGN) Stock Price Down 8% on Insider SellingSeptember 12, 2025 | marketbeat.comUrogen Pharma (NASDAQ:URGN) Insider Mark Schoenberg Sells 871 SharesSeptember 11, 2025 | marketbeat.comUrogen Pharma (NASDAQ:URGN) General Counsel Jason Drew Smith Sells 1,520 SharesSeptember 11, 2025 | marketbeat.comUrogen Pharma (NASDAQ:URGN) Reaches New 12-Month High - Should You Buy?September 11, 2025 | marketbeat.comUrogen Pharma (NASDAQ:URGN) Shares Down 8% Following Insider SellingSeptember 11, 2025 | americanbankingnews.comUrogen Pharma (NASDAQ:URGN) Shares Up 10.6% - What's Next?September 10, 2025 | marketbeat.comUrogen Pharma (NASDAQ:URGN) Insider Sells $16,644.81 in StockSeptember 10, 2025 | insidertrades.comUroGen Pharma announces inducement grants under Nasdaq listing ruleSeptember 9, 2025 | msn.comUroGen Pharma Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)September 8, 2025 | globenewswire.comUrogen Pharma $URGN Holdings Boosted by Parkman Healthcare Partners LLCSeptember 8, 2025 | marketbeat.comUrogen Pharma $URGN Stock Position Decreased by Adage Capital Partners GP L.L.C.September 8, 2025 | marketbeat.comUrogen Pharma (NASDAQ:URGN) Receives Consensus Rating of "Buy" from AnalystsSeptember 8, 2025 | marketbeat.comUrogen Pharma (NASDAQ:URGN) Given Consensus Rating of "Buy" by AnalystsSeptember 7, 2025 | americanbankingnews.comVestal Point Capital LP Boosts Position in Urogen Pharma $URGNSeptember 4, 2025 | marketbeat.comRA Capital Management L.P. Acquires Shares of 3,206,271 Urogen Pharma $URGNSeptember 4, 2025 | marketbeat.comNuveen LLC Invests $1.03 Million in Urogen Pharma $URGNSeptember 3, 2025 | marketbeat.comPartners Capital Investment Group LLP Invests $170,000 in Urogen Pharma $URGNAugust 24, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeAKBA, URGN, PBYI, and MRNS Company DescriptionsAkebia Therapeutics NASDAQ:AKBA$2.96 +0.16 (+5.71%) Closing price 04:00 PM EasternExtended Trading$2.96 +0.00 (+0.17%) As of 05:27 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Akebia Therapeutics, Inc., a biopharmaceutical company, focuses on the development and commercialization of therapeutics for patients with kidney diseases. The company's lead product investigational product candidate is Vafseo (vadadustat), an oral hypoxia-inducible factor prolyl hydroxylase, which is in Phase III development for the treatment of anemia due to chronic kidney disease (CKD) in dialysis-dependent and non-dialysis dependent patients. It offers Auryxia, a ferric citrate that is used to control the serum phosphorus levels in adult patients with DD-CKD on dialysis; and the treatment of iron deficiency anemia in adult patients with CKD not on dialysis. The company's product pipeline includes AKB-9090, a drug targeting critical-care indications; and AKB-10108, a drug targeting conditions related to premature birth. It has collaboration agreements with Mitsubishi Tanabe Pharma Corporation for the development and commercialization of vadadustat in Japan and other Asian countries, as well as research and license agreement with Janssen Pharmaceutica NV for the development and commercialization of hypoxia-inducible factor prolyl hydroxylase targeted compounds worldwide. Akebia Therapeutics, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.Marinus Pharmaceuticals NASDAQ:MRNSMarinus Pharmaceuticals, Inc., a pharmaceutical company, focuses on development and commercialization of therapeutic products for patients suffering from rare genetic epilepsies and other seizure disorders. It offers ZTALMY (ganaxolone), an oral suspension for the treatment of seizures associated with cyclin-dependent kinase-like 5 deficiency disorder for adult and pediatric patient populations in acute and chronic care, and in-patient and self-administered settings. The company's ZTALMY product candidate acts at synaptic and extrasynaptic GABAA receptors, a target for its anti-seizure, antidepressant, and anxiolytic potential. It is developing ganaxolone for treating genetic epilepsy disorders, such as PCDH19-related epilepsy, and tuberous sclerosis complex. Marinus Pharmaceuticals, Inc. has license agreement with Purdue Neuroscience Company and CyDex Pharmaceuticals, Inc.; and collaboration agreement with Orion Corporation and Tenacia Biotechnology (Shanghai) Co., Ltd. Marinus Pharmaceuticals, Inc. was incorporated in 2003 and is headquartered in Radnor, Pennsylvania.Puma Biotechnology NASDAQ:PBYI$4.52 +0.18 (+4.15%) Closing price 04:00 PM EasternExtended Trading$4.51 -0.01 (-0.22%) As of 04:20 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. The company offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. It also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. The company sells its products through specialty pharmacy and distributor networks. It has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds; and Takeda Pharmaceutical Company Limited for the research, development, and commercialization of alisertib, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. The company was founded in 2010 and is headquartered in Los Angeles, California.Urogen Pharma NASDAQ:URGN$18.87 +0.77 (+4.25%) Closing price 04:00 PM EasternExtended Trading$18.54 -0.34 (-1.78%) As of 05:22 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.UroGen Pharma Ltd., a biotechnology company, engages in the development and commercialization of solutions for urothelial and specialty cancers. It offers RTGel, a novel proprietary polymeric biocompatible, reverse thermal gelation hydrogel technology to improve therapeutic profiles of existing drugs; and Jelmyto for pyelocalyceal solution. The company's lead product candidate is UGN-102 for the treatment of several forms of non-muscle invasive urothelial cancer that include low-grade upper tract urothelial cancer and low-grade intermediate risk non-muscle invasive bladder cancer (NMIBC). It is also developing UGN-301 for the treatment of high-grade NMIBC. The company has license agreement with Agenus Inc. to develop, make, use, sell, import, and commercialize products of Agenus for the treatment of cancers of the urinary tract via intravesical delivery; strategic research collaboration agreement with MD Anderson focusing on the sequential use of UGN-201 and UGN-301 for the treatment of NMIBC; and licensing and supply agreement with medac Gesellschaft für klinische Spezialpräparate m.b.H. to develop UGN-103 in low-grade intermediate risk NMIBC and UGN-104 in low-grade upper tract urothelial carcinoma. UroGen Pharma Ltd. was incorporated in 2004 and is based in Princeton, New Jersey. 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