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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ARDX NASDAQ:AXSM NASDAQ:CRSP NASDAQ:NUVL On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeARDXArdelyx$6.20+2.3%$4.68$3.21▼$7.18$1.46B0.684.68 million shs1.79 million shsAXSMAxsome Therapeutics$121.15+4.2%$107.04$75.56▼$139.13$5.80B0.51585,898 shs547,162 shsCRSPCRISPR Therapeutics$54.88+1.4%$55.23$30.04▼$71.13$4.92B1.82.93 million shs1.28 million shsNUVLNuvalent$74.93+1.2%$78.49$55.53▼$113.51$5.34B1.3437,023 shs359,402 shs(Almost) Everything You Need To Know About The EV MarketLooking to profit from the electric vehicle mega-trend? Enter your email address and we'll send you our list of which EV stocks show the most long-term potential.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceARDXArdelyx-0.82%+4.30%+41.26%+52.64%-4.57%AXSMAxsome Therapeutics-1.86%+4.66%+15.35%+11.86%+32.19%CRSPCRISPR Therapeutics-0.35%-6.01%-16.41%+44.08%+11.17%NUVLNuvalent-2.67%-1.28%-9.04%+2.46%-13.21%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationARDXArdelyx4.2713 of 5 stars3.52.00.04.42.82.50.6AXSMAxsome Therapeutics4.8215 of 5 stars4.51.00.04.54.14.20.6CRSPCRISPR Therapeutics3.6343 of 5 stars4.33.00.00.02.23.30.6NUVLNuvalent3.3617 of 5 stars4.51.00.00.03.33.30.0Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceARDXArdelyx 3.00Buy$11.5085.48% UpsideAXSMAxsome Therapeutics 3.07Buy$178.0046.93% UpsideCRSPCRISPR Therapeutics 2.50Moderate Buy$71.6030.47% UpsideNUVLNuvalent 3.08Buy$118.9158.69% UpsideCurrent Analyst Ratings BreakdownLatest ARDX, NUVL, AXSM, and CRSP Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails8/19/2025NUVLNuvalentPiper SandlerSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$112.008/7/2025CRSPCRISPR TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$65.00 ➝ $80.008/6/2025ARDXArdelyxPiper SandlerSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetNeutral ➝ Neutral$8.00 ➝ $9.008/6/2025CRSPCRISPR TherapeuticsBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetEqual Weight ➝ Equal Weight$42.00 ➝ $56.008/5/2025ARDXArdelyxUBS GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingSet Price Target$12.008/5/2025ARDXArdelyxRaymond James FinancialSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform$11.00 ➝ $12.008/5/2025ARDXArdelyxWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform$13.00 ➝ $14.008/5/2025AXSMAxsome TherapeuticsBank of AmericaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$173.00 ➝ $176.008/5/2025AXSMAxsome TherapeuticsRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOutperform ➝ Outperform$184.00 ➝ $189.008/5/2025CRSPCRISPR TherapeuticsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$82.008/5/2025CRSPCRISPR TherapeuticsRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetSector Perform ➝ Sector Perform$38.00 ➝ $42.00(Data available from 8/26/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookARDXArdelyx$333.61M4.48N/AN/A$0.58 per share10.69AXSMAxsome Therapeutics$385.69M15.67N/AN/A$1.46 per share82.98CRSPCRISPR Therapeutics$37.31M133.78N/AN/A$18.81 per share2.92NUVLNuvalentN/AN/AN/AN/A$13.03 per shareN/ACompare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateARDXArdelyx-$39.14M-$0.23N/A20.00N/A-14.60%-36.57%-13.42%10/30/2025 (Estimated)AXSMAxsome Therapeutics-$287.22M-$5.07N/A42.96N/A-49.88%-283.22%-33.06%11/11/2025 (Estimated)CRSPCRISPR Therapeutics-$366.25M-$5.43N/AN/AN/A-1,229.43%-20.05%-17.09%11/4/2025 (Estimated)NUVLNuvalent-$260.76M-$4.90N/AN/AN/AN/A-32.58%-30.14%11/11/2025 (Estimated)Latest ARDX, NUVL, AXSM, and CRSP EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/7/2025Q2 2025NUVLNuvalent-$1.27-$1.31-$0.04-$1.39N/AN/A8/4/2025Q2 2025ARDXArdelyx-$0.13-$0.08+$0.05-$0.08$82.69 million$97.66 million8/4/2025Q2 2025AXSMAxsome Therapeutics-$1.00-$0.92+$0.08-$0.97$140.02 million$150.04 million8/4/2025Q2 2025CRSPCRISPR Therapeutics-$1.47-$1.29+$0.18-$2.40$6.44 million$0.89 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthARDXArdelyxN/AN/AN/AN/AN/AAXSMAxsome TherapeuticsN/AN/AN/AN/AN/ACRSPCRISPR TherapeuticsN/AN/AN/AN/AN/ANUVLNuvalentN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioARDXArdelyx1.444.304.03AXSMAxsome Therapeutics1.661.571.51CRSPCRISPR TherapeuticsN/A16.6116.61NUVLNuvalentN/A13.5713.57Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipARDXArdelyx58.92%AXSMAxsome Therapeutics81.49%CRSPCRISPR Therapeutics69.20%NUVLNuvalent97.26%Insider OwnershipCompanyInsider OwnershipARDXArdelyx4.80%AXSMAxsome Therapeutics22.40%CRSPCRISPR Therapeutics4.10%NUVLNuvalent10.20%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableARDXArdelyx90240.98 million229.42 millionOptionableAXSMAxsome Therapeutics38049.90 million38.72 millionOptionableCRSPCRISPR Therapeutics46090.95 million87.22 millionOptionableNUVLNuvalent4072.11 million64.75 millionOptionableARDX, NUVL, AXSM, and CRSP HeadlinesRecent News About These CompaniesT. Rowe Price Investment Management Inc. Makes New $31.97 Million Investment in Nuvalent, Inc. $NUVLAugust 26 at 4:49 AM | marketbeat.comNuvalent, Inc. $NUVL Shares Purchased by American Century Companies Inc.August 26 at 3:50 AM | marketbeat.comNuvalent, Inc. $NUVL Shares Purchased by Wellington Management Group LLPAugust 24 at 5:15 AM | marketbeat.comNuvalent, Inc. $NUVL Shares Sold by Deutsche Bank AGAugust 24 at 3:28 AM | marketbeat.comNuvalent, Inc. $NUVL Shares Sold by Charles Schwab Investment Management Inc.August 24 at 3:18 AM | marketbeat.comCandriam S.C.A. Sells 13,966 Shares of Nuvalent, Inc. $NUVLAugust 23 at 7:05 AM | marketbeat.comAberdeen Group plc Acquires 19,987 Shares of Nuvalent, Inc. $NUVLAugust 23 at 4:34 AM | marketbeat.comNuvalent, Inc. $NUVL Shares Purchased by Russell Investments Group Ltd.August 22, 2025 | marketbeat.comNuvalent (NASDAQ:NUVL) CEO Sells $2,036,340.00 in StockAugust 21, 2025 | marketbeat.comNuvalent (NASDAQ:NUVL) Now Covered by Piper SandlerAugust 21, 2025 | marketbeat.comInsider Selling: Nuvalent (NASDAQ:NUVL) CEO Sells 27,000 Shares of StockAugust 20, 2025 | insidertrades.comPiper Sandler Initiates Coverage on Nuvalent (NASDAQ:NUVL)August 20, 2025 | americanbankingnews.comPiper Sandler Initiates Coverage of Nuvalent (NUVL) with Overweight RecommendationAugust 19, 2025 | msn.comNuvalent initiated with an Overweight at Piper SandlerAugust 19, 2025 | msn.comVanguard Group Inc. Decreases Holdings in Nuvalent, Inc. $NUVLAugust 19, 2025 | marketbeat.comLord Abbett & CO. LLC Sells 112,621 Shares of Nuvalent, Inc. (NASDAQ:NUVL)August 18, 2025 | marketbeat.comCitigroup Inc. Purchases 112,519 Shares of Nuvalent, Inc. (NASDAQ:NUVL)August 15, 2025 | marketbeat.comNuvalent to Present Pivotal Data from ARROS-1 Clinical Trial of Zidesamtinib for TKI Pre-treated Patients with Advanced ROS1-positive NSCLC at WCLC 2025 Presidential SymposiumAugust 13, 2025 | prnewswire.comWedbush Forecasts Nuvalent's Q3 Earnings (NASDAQ:NUVL)August 11, 2025 | marketbeat.comInsider Selling: Nuvalent, Inc. (NASDAQ:NUVL) Insider Sells 5,500 Shares of StockAugust 10, 2025 | marketbeat.comNuvalent, Inc. (NASDAQ:NUVL) Insider Henry E. Pelish Sells 5,500 SharesAugust 9, 2025 | insidertrades.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeARDX, NUVL, AXSM, and CRSP Company DescriptionsArdelyx NASDAQ:ARDX$6.20 +0.14 (+2.31%) Closing price 04:00 PM EasternExtended Trading$6.17 -0.03 (-0.48%) As of 07:42 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Ardelyx, Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines to treat gastrointestinal and cardiorenal therapeutic areas in the United States and internationally. The company's lead product candidate is tenapanor for the treatment of patients with irritable bowel syndrome with constipation. It also develops XPHOZAH, which is in Phase III clinical trial to reduce serum phosphorus in adults with chronic kidney disease (CKD)on dialysis, or hyperphosphatemia; RDX013, a potassium secretagogue, for the treatment of elevated serum potassium, or hyperkalemia, a problem among patients with kidney and/or heart failure; and RDX020, for adult patients with metabolic acidosis, a serious electrolyte disorder. The company has agreements with Kyowa Kirin, Fosun Pharmaceutical Industrial Development Co. Ltd., and Knight Therapeutics, Inc. for the development and commercialization of tenapanor in their respective territories. The company was formerly known as Nteryx, Inc. and changed its name to Ardelyx, Inc. in June 2008. Ardelyx, Inc. was incorporated in 2007 and is headquartered in Waltham, Massachusetts.Axsome Therapeutics NASDAQ:AXSM$121.15 +4.84 (+4.16%) Closing price 04:00 PM EasternExtended Trading$121.15 0.00 (0.00%) As of 07:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist with multimodal activity indicated for the treatment of major depressive disorder; and Sunosi (solriamfetol), a medication indicated to the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea. It is also developing AXS-05, which is in Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation; AXS-07, an investigational medicine that has completed Phase III trials for the acute treatment of migraine; AXS-12, an investigational medicine, which is in Phase III trial to treat narcolepsy; AXS-14, a selective and potent norepinephrine reuptake inhibitor that has completed Phase III trial for the treatment of fibromyalgia and other conditions; and solriamfetol, a dual-acting dopamine and norepinephrine reuptake inhibitor, which has completed a Phase 2 trial for treating attention-deficit/hyperactivity disorder, and is in phase 2 major depressive, binge eating, and shift work disorder. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.CRISPR Therapeutics NASDAQ:CRSP$54.88 +0.75 (+1.39%) Closing price 04:00 PM EasternExtended Trading$54.90 +0.02 (+0.04%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.CRISPR Therapeutics is a gene-editing company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. CRISPR/Cas9 is a revolutionary gene-editing technology that allows for precise, directed changes to genomic DNA. CRISPR Therapeutics has established a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine and rare diseases. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic collaborations with companies including Bayer, Vertex Pharmaceuticals and ViaCyte, Inc. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California and London, United Kingdom. For more information, please visit www.crisprtx.com.Nuvalent NASDAQ:NUVL$74.93 +0.88 (+1.19%) Closing price 04:00 PM EasternExtended Trading$74.95 +0.02 (+0.03%) As of 04:34 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Nuvalent, Inc., a clinical stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are NVL-520, a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; NVL-655, a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the phase 2 portion of the ALKOVE-1 Phase 1/2 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR, which is expected to initiate phase 1 trial. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts. 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