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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
AVXS AveXis	$217.83	$0.00	$65.54 ▼ $217.94	N/A	N/A	816,305 shs	222 shs
ELOX Eloxx Pharmaceuticals		$0.11	$0.00 ▼ $0.75	N/A	-1538.18	1,538 shs	N/A
PLX Protalix BioTherapeutics	$1.66 +5.1%	$1.49	$0.89 ▼ $3.10	$132.36M	-0.21	835,539 shs	690,192 shs
PRME Prime Medicine	$3.55 +10.2%	$3.50	$1.11 ▼ $5.17	$477.74M	2.39	2.53 million shs	3.10 million shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
AVXS AveXis	0.00%	0.00%	0.00%	0.00%	0.00%
ELOX Eloxx Pharmaceuticals	0.00%	0.00%	0.00%	0.00%	-99.99%
PLX Protalix BioTherapeutics	0.00%	+12.16%	+7.10%	+2.47%	+71.15%
PRME Prime Medicine	0.00%	-0.56%	-18.39%	+175.19%	-19.32%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	Dividend Strength	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
AVXS AveXis	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
ELOX Eloxx Pharmaceuticals	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
PLX Protalix BioTherapeutics	3.0027 of 5 stars	3.5	2.0	0.0	0.0	1.7	1.7	1.9
PRME Prime Medicine	2.7248 of 5 stars	3.4	1.0	0.0	0.0	1.3	5.0	0.6

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
AVXS AveXis	0.00	N/A	N/A	N/A
ELOX Eloxx Pharmaceuticals	0.00	N/A	N/A	N/A
PLX Protalix BioTherapeutics	3.00	Buy	$15.00	803.61% Upside
PRME Prime Medicine	2.75	Moderate Buy	$8.92	151.17% Upside

Current Analyst Ratings Breakdown

Latest AVXS, ELOX, PRME, and PLX Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
8/8/2025	PRME Prime Medicine	Chardan Capital Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Buy ➝ Buy	$12.00 ➝ $10.00
7/16/2025	PRME Prime Medicine	Wedbush Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Outperform	$8.00
5/27/2025	PRME Prime Medicine	Citigroup Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Neutral	$10.00 ➝ $1.50

(Data available from 8/24/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
AVXS AveXis	N/A	N/A	N/A	N/A	N/A	N/A
ELOX Eloxx Pharmaceuticals	N/A	N/A	N/A	N/A	N/A	N/A
PLX Protalix BioTherapeutics	$61.95M	2.14	$0.09 per share	17.80	$0.47 per share	3.53
PRME Prime Medicine	$4.96M	96.30	N/A	N/A	$1.37 per share	2.59

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
AVXS AveXis	N/A	N/A	0.00	∞	N/A	N/A	N/A	N/A	N/A
ELOX Eloxx Pharmaceuticals	-$36.06M	N/A	0.00	N/A	N/A	N/A	N/A	N/A	N/A
PLX Protalix BioTherapeutics	$8.31M	$0.07	N/A	5.35	N/A	-21.03%	-30.89%	-11.74%	N/A
PRME Prime Medicine	-$198.13M	-$1.56	N/A	N/A	N/A	N/A	-107.87%	-74.97%	N/A

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
AVXS AveXis	N/A	N/A	N/A	N/A	N/A
ELOX Eloxx Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
PLX Protalix BioTherapeutics	N/A	N/A	N/A	N/A	N/A
PRME Prime Medicine	$1.45	40.73%	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
AVXS AveXis	N/A	N/A	N/A
ELOX Eloxx Pharmaceuticals	N/A	N/A	N/A
PLX Protalix BioTherapeutics	N/A	1.98	1.27
PRME Prime Medicine	N/A	6.50	6.50

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
AVXS AveXis	84.14%
ELOX Eloxx Pharmaceuticals	2.90%
PLX Protalix BioTherapeutics	16.53%
PRME Prime Medicine	70.37%

Insider Ownership

Company	Insider Ownership
AVXS AveXis	18.60%
ELOX Eloxx Pharmaceuticals	20.20%
PLX Protalix BioTherapeutics	6.50%
PRME Prime Medicine	22.74%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
AVXS AveXis	N/A	N/A	N/A	Optionable
ELOX Eloxx Pharmaceuticals	30	3.14 million	2.51 million	Not Optionable
PLX Protalix BioTherapeutics	200	79.73 million	69.00 million	Optionable
PRME Prime Medicine	234	134.57 million	100.38 million	Optionable

AVXS, ELOX, PRME, and PLX Headlines

Recent News About These Companies

Analysts Set Prime Medicine, Inc. (NYSE:PRME) Target Price at $8.92

August 21 at 2:18 AM | americanbankingnews.com

Positive Signs As Multiple Insiders Buy Prime Medicine Stock

August 20, 2025 | uk.finance.yahoo.com

Prime Medicine, Inc. (NYSE:PRME) Given Consensus Rating of "Moderate Buy" by Analysts

August 19, 2025 | marketbeat.com

Analysts Set Expectations for Prime Medicine FY2025 Earnings

August 16, 2025 | marketbeat.com

Q3 EPS Estimates for Prime Medicine Cut by HC Wainwright

August 16, 2025 | marketbeat.com

HC Wainwright Cuts Earnings Estimates for Prime Medicine

August 16, 2025 | americanbankingnews.com

Chardan Capital Lowers Prime Medicine (NYSE:PRME) Price Target to $10.00

August 10, 2025 | marketbeat.com

Prime Medicine, Inc.: Strong Buy Rating Backed by Promising Pipeline and Robust Financial Position

August 8, 2025 | tipranks.com

PRME Revenue Misses by 73%

August 8, 2025 | aol.comA

Prime Medicine, Inc. (PRME) Reports Q2 Loss, Lags Revenue Estimates

August 7, 2025 | zacks.com

Prime Medicine Reports Second Quarter 2025 Financial Results and Provides Business Updates

August 7, 2025 | globenewswire.com

Prime Medicine (NYSE:PRME) Trading Down 6.7% - Here's What Happened

August 6, 2025 | marketbeat.com

Prime Medicine Holds Special Stockholder Meeting

August 5, 2025 | tipranks.com

Prime Medicine (NYSE:PRME) Shares Gap Up on Insider Buying Activity

August 5, 2025 | marketbeat.com

Friday’s Insider Trades: Key Buys and Sells in US Stocks Revealed

August 4, 2025 | investing.com

Arch Venture Partners Xii, Llc Purchases 3,030,300 Shares of Prime Medicine, Inc. (NYSE:PRME) Stock

August 2, 2025 | marketbeat.com

Prime Medicine, Inc. (NYSE:PRME) Major Shareholder Arch Venture Partners Xii, Llc Purchases 3,030,300 Shares

August 2, 2025 | insidertrades.com

Prime Medicine Halts Sales Agreement Prospectus

August 1, 2025 | theglobeandmail.com

Prime Medicine Announces Closing of Public Offering and Full Exercise of the Underwriters’ Option to Purchase Additional Shares

August 1, 2025 | finance.yahoo.com

Prime Medicine Announces Closing of Public Offering and Full Exercise of the Underwriters' Option to Purchase Additional Shares

August 1, 2025 | globenewswire.com

Prime Medicine (NYSE:PRME) Shares Gap Down - Here's Why

August 1, 2025 | marketbeat.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

AVXS, ELOX, PRME, and PLX Company Descriptions

AveXis NASDAQ:AVXS

AveXis, Inc., a clinical-stage gene therapy company, engages in developing and commercializing treatments for patients suffering from rare and life-threatening neurological genetic diseases. Its initial product candidate is AVXS-101, a gene therapy product candidate that has completed Phase I clinical trial for the treatment of spinal muscular atrophy Type 1. The company also intends to identify, acquire, develop, and commercialize gene therapy product candidates for the treatment of other rare and life-threatening neurological genetic diseases. It has strategic collaboration and license agreements with Nationwide Children's Hospital; The Research Institute at Nationwide Children's Hospital; REGENXBIO Inc.; and Asklepios Biopharmaceutical, Inc. The company was formerly known as BioLife Cell Bank, Inc. and changed its name to AveXis, Inc. in January 2014. AveXis, Inc. was founded in 2010 and is headquartered in Bannockburn, Illinois.

Eloxx Pharmaceuticals NASDAQ:ELOX

Eloxx Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on developing ribosome modulation for the treatment of rare and ultra-rare premature stop codon diseases. Its lead investigational drug product candidate is ELX-02, which is in Phase 2 clinical trial for the treatment of cystic fibrosis and nephropathic cystinosis patients with diagnosed nonsense mutations. The company also develops various preclinical programs for the treatment of alport syndrome, recessive dystrophic epidermolysis bullosa, junctional epidermolysis bullosa, and familial adenomatous polyposis, as well as various earlier discovery stage programs in oncology. Eloxx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Watertown, Massachusetts.

Protalix BioTherapeutics NYSE:PLX

$1.66 +0.08 (+5.06%)

Closing price 08/22/2025 04:00 PM Eastern

Extended Trading

$1.64 -0.02 (-1.51%)

As of 08/22/2025 07:11 PM Eastern

Protalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on its proprietary ProCellEx plant cell-based protein expression system in the United States, Australia, Canada, Israel, Brazil, Russia, Turkey, and internationally. The company offers Elelyso for the treatment of Gaucher disease; and Elfabrio for the treatment of adult patients with a confirmed diagnosis of Fabry disease. It is also developing PRX-115, a plant cell-expressed recombinant PEGylated Uricase which is in Phase I trial for the treatment of gout; and PRX-119, a plant cell-expressed PEGylated recombinant human DNase I product candidate that is in preclinical phase for the treatment of NETs-related diseases. The company has agreements and partnerships with Pfizer; Fundação Oswaldo Cruz; and Chiesi Farmaceutici S.p.A. The company was incorporated in 1993 and is headquartered in Karmiel, Israel. Protalix BioTherapeutics, Inc. is a subsidiary of Protalix Ltd.

Prime Medicine NYSE:PRME

$3.55 +0.33 (+10.25%)

Closing price 08/22/2025 04:00 PM Eastern

Extended Trading

$3.57 +0.02 (+0.56%)

As of 08/22/2025 07:40 PM Eastern

Prime Medicine, Inc., a biotechnology company, delivers genetic therapies to address the spectrum of diseases by deploying gene editing technology. The company offers Prime Editors with a Prime Editor protein, comprising a fusion between a Cas protein and a reverse transcriptase enzyme; and a pegRNA, which targets the Prime Editor to a specific genomic location and provides a template for making the desired edit to the target DNA sequence. It has a research collaboration with Cimeio Therapeutics to develop Prime Edited Shielded-Cell & Immunotherapy Pairs for genetic diseases, acute myeloid leukemia, and myelodysplastic syndrome. The company was incorporated in 2019 and is based in Cambridge, Massachusetts.

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Comparative Price Performance Over Time