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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare OTCMKTS:BLUSF NASDAQ:EIDX NASDAQ:HRTX NASDAQ:IRWD NASDAQ:LGND On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeBLUSFBELLUS Health$9.77$0.49▼$2.60$2.35B1.5539,610 shs3.45 million shsEIDXEidos Therapeutics$122.21$123.21$28.39▼$132.54$4.75B-0.16128,113 shsN/AHRTXHeron Therapeutics$1.25+0.4%$1.61$1.04▼$2.68$228.23M1.231.65 million shs206,543 shsIRWDIronwood Pharmaceuticals$1.31+2.7%$0.99$0.53▼$5.13$211.98M0.332.69 million shs198,263 shsLGNDLigand Pharmaceuticals$164.81-0.4%$147.13$93.58▼$169.49$3.23B0.96150,201 shs52,642 shsA Guide To High-Short-Interest StocksMarketBeat's analysts have just released their top five short plays for September 2025. Learn which stocks have the most short interest and how to trade them. Enter your email address to see which companies made the list.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceBLUSFBELLUS Health0.00%0.00%0.00%0.00%0.00%EIDXEidos Therapeutics0.00%0.00%0.00%0.00%0.00%HRTXHeron Therapeutics-1.59%-4.62%-6.77%-36.41%-33.69%IRWDIronwood Pharmaceuticals-2.29%+13.27%+24.27%+101.70%-71.99%LGNDLigand Pharmaceuticals-0.14%-0.21%+9.55%+47.07%+57.97%Compare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeBLUSFBELLUS Health$9.77$0.49▼$2.60$2.35B1.5539,610 shs3.45 million shsEIDXEidos Therapeutics$122.21$123.21$28.39▼$132.54$4.75B-0.16128,113 shsN/AHRTXHeron Therapeutics$1.25+0.4%$1.61$1.04▼$2.68$228.23M1.231.65 million shs206,543 shsIRWDIronwood Pharmaceuticals$1.31+2.7%$0.99$0.53▼$5.13$211.98M0.332.69 million shs198,263 shsLGNDLigand Pharmaceuticals$164.81-0.4%$147.13$93.58▼$169.49$3.23B0.96150,201 shs52,642 shsA Guide To High-Short-Interest StocksMarketBeat's analysts have just released their top five short plays for September 2025. Learn which stocks have the most short interest and how to trade them. Enter your email address to see which companies made the list.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceBLUSFBELLUS Health0.00%0.00%0.00%0.00%0.00%EIDXEidos Therapeutics0.00%0.00%0.00%0.00%0.00%HRTXHeron Therapeutics-1.59%-4.62%-6.77%-36.41%-33.69%IRWDIronwood Pharmaceuticals-2.29%+13.27%+24.27%+101.70%-71.99%LGNDLigand Pharmaceuticals-0.14%-0.21%+9.55%+47.07%+57.97%Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceBLUSFBELLUS Health 0.00N/AN/AN/AEIDXEidos Therapeutics 0.00N/AN/AN/AHRTXHeron Therapeutics 2.33Hold$4.50261.45% UpsideIRWDIronwood Pharmaceuticals 2.14Hold$4.94275.95% UpsideLGNDLigand Pharmaceuticals 3.00Buy$176.507.10% UpsideCurrent Analyst Ratings BreakdownLatest LGND, IRWD, HRTX, EIDX, and BLUSF Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails9/5/2025IRWDIronwood PharmaceuticalsZacks ResearchSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingDowngradeStrong-Buy ➝ Hold9/3/2025LGNDLigand PharmaceuticalsOppenheimerSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetOutperform$167.00 ➝ $190.009/2/2025LGNDLigand PharmaceuticalsBenchmarkSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetBuy$160.00 ➝ $175.008/28/2025LGNDLigand PharmaceuticalsHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetBuy$157.00 ➝ $206.008/12/2025HRTXHeron TherapeuticsZacks ResearchSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeStrong Sell8/8/2025HRTXHeron TherapeuticsNeedham & Company LLCSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetBuy$4.00 ➝ $3.008/8/2025LGNDLigand PharmaceuticalsRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetOutperform$155.00 ➝ $185.007/30/2025LGNDLigand PharmaceuticalsOppenheimerSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingBoost Price TargetOutperform$145.00 ➝ $162.00(Data available from 9/16/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookBLUSFBELLUS Health$30K0.00N/AN/A$0.25 per share0.00EIDXEidos Therapeutics$26.69M177.99N/AN/A$4.57 per share26.74HRTXHeron Therapeutics$144.29M1.58N/AN/A($0.22) per share-5.66IRWDIronwood Pharmaceuticals$308.52M0.69$0.05 per share26.49($1.88) per share-0.70LGNDLigand Pharmaceuticals$167.13M19.33$1.60 per share103.15$43.95 per share3.75Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateBLUSFBELLUS Health-$7.01M-$0.10N/AN/AN/A-49,910.34%-48.37%-45.25%N/AEIDXEidos Therapeutics-$37.83M-$1.03N/AN/AN/AN/A-65.21%-53.04%N/AHRTXHeron Therapeutics-$13.58M-$0.02N/AN/AN/A-0.62%N/A-0.40%11/11/2025 (Estimated)IRWDIronwood Pharmaceuticals$880K-$0.05N/A5.26N/A-2.25%-2.46%2.19%11/6/2025 (Estimated)LGNDLigand Pharmaceuticals-$4.03M-$4.00N/A44.42N/A-40.44%-9.21%-8.09%11/6/2025 (Estimated)Latest LGND, IRWD, HRTX, EIDX, and BLUSF EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/8/2025Q2 2025HRTXHeron Therapeutics-$0.01-$0.02-$0.01-$0.02$38.08 million$37.20 million8/7/2025Q2 2025IRWDIronwood Pharmaceuticals-$0.02$0.14+$0.16$0.14$62.02 million$85.24 million8/7/2025Q2 2025LGNDLigand Pharmaceuticals$1.54$1.60+$0.06$0.24$43.87 million$47.63 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthBLUSFBELLUS HealthN/AN/AN/AN/AN/AEIDXEidos TherapeuticsN/AN/AN/AN/AN/AHRTXHeron TherapeuticsN/AN/AN/AN/AN/AIRWDIronwood PharmaceuticalsN/AN/AN/AN/AN/ALGNDLigand PharmaceuticalsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioBLUSFBELLUS HealthN/A13.8713.87EIDXEidos Therapeutics0.1411.1011.10HRTXHeron TherapeuticsN/A0.820.53IRWDIronwood PharmaceuticalsN/A0.820.82LGNDLigand PharmaceuticalsN/A5.455.21Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipBLUSFBELLUS HealthN/AEIDXEidos Therapeutics31.40%HRTXHeron Therapeutics80.01%IRWDIronwood PharmaceuticalsN/ALGNDLigand Pharmaceuticals91.28%Insider OwnershipCompanyInsider OwnershipBLUSFBELLUS Health24.17%EIDXEidos Therapeutics70.10%HRTXHeron Therapeutics5.86%IRWDIronwood Pharmaceuticals12.70%LGNDLigand Pharmaceuticals7.00%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableBLUSFBELLUS Health10159.12 millionN/ANot OptionableEIDXEidos Therapeutics7038.87 millionN/ANot OptionableHRTXHeron Therapeutics300183.32 million172.57 millionOptionableIRWDIronwood Pharmaceuticals220162.43 million141.81 millionOptionableLGNDLigand Pharmaceuticals8019.60 million18.23 millionOptionableLGND, IRWD, HRTX, EIDX, and BLUSF HeadlinesRecent News About These CompaniesRhumbline Advisers Sells 1,989 Shares of Ligand Pharmaceuticals Incorporated $LGNDSeptember 15 at 4:59 AM | marketbeat.comEllsworth Advisors LLC Makes New Investment in Ligand Pharmaceuticals Incorporated $LGNDSeptember 13 at 6:52 AM | marketbeat.comLigand Pharmaceuticals Incorporated (NASDAQ:LGND) Sees Large Growth in Short InterestSeptember 11, 2025 | marketbeat.comBaird Financial Group Inc. Reduces Stock Position in Ligand Pharmaceuticals Incorporated $LGNDSeptember 10, 2025 | marketbeat.comJacobs Levy Equity Management Inc. Invests $16.53 Million in Ligand Pharmaceuticals Incorporated $LGNDSeptember 9, 2025 | marketbeat.comLigand Pharmaceuticals Incorporated $LGND Shares Bought by Clark Capital Management Group Inc.September 7, 2025 | marketbeat.comLigand Pharmaceuticals (NASDAQ:LGND) Price Target Raised to $190.00 at OppenheimerSeptember 5, 2025 | marketbeat.comInsider Selling: Ligand Pharmaceuticals (NASDAQ:LGND) Director Sells 467 Shares of StockSeptember 5, 2025 | insidertrades.comLigand Pharmaceuticals (NASDAQ:LGND) Sets New 52-Week High After Analyst UpgradeSeptember 5, 2025 | marketbeat.comLigand Pharmaceuticals (NASDAQ:LGND) Sets New 52-Week High Following Analyst UpgradeSeptember 5, 2025 | americanbankingnews.comBenchmark Forecasts Strong Price Appreciation for Ligand Pharmaceuticals (NASDAQ:LGND) StockSeptember 4, 2025 | marketbeat.comWhat Analysts Are Saying About Ligand Pharmaceuticals StockSeptember 3, 2025 | benzinga.comLigand Pharmaceuticals Incorporated $LGND Stake Reduced by Ashford Capital Management Inc.September 1, 2025 | marketbeat.comLigand Pharmaceuticals Incorporated $LGND Shares Acquired by Northern Trust CorpSeptember 1, 2025 | marketbeat.comLigand Pharmaceuticals Incorporated $LGND Shares Purchased by American Century Companies Inc.September 1, 2025 | marketbeat.comLigand Pharmaceuticals (NASDAQ:LGND) Reaches New 52-Week High Following Analyst UpgradeAugust 31, 2025 | marketbeat.comNuveen LLC Buys New Stake in Ligand Pharmaceuticals Incorporated $LGNDAugust 29, 2025 | marketbeat.comLigand Pharmaceuticals Incorporated (NASDAQ:LGND) Receives Consensus Rating of "Buy" from BrokeragesAugust 26, 2025 | marketbeat.comLigand Pharmaceuticals Incorporated $LGND Shares Bought by CW Advisors LLCAugust 24, 2025 | marketbeat.comInvesco Ltd. Purchases 8,473 Shares of Ligand Pharmaceuticals Incorporated $LGNDAugust 23, 2025 | marketbeat.comA Fresh Look at Ligand Pharmaceuticals (LGND) Valuation Following $400 Million Convertible Note Offering and Capital Structure ShiftAugust 22, 2025 | finance.yahoo.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeLGND, IRWD, HRTX, EIDX, and BLUSF Company DescriptionsBELLUS Health OTCMKTS:BLUSFBELLUS Health, Inc. is a biopharmaceutical development company, which engages in the research and development of products that provide health solutions and address critical unmet medical needs. Its products include BLU-5937, KIACTA, AMO-01, and ALZ-801. The company was founded on June 17, 1993 and is headquartered in Laval, Canada.Eidos Therapeutics NASDAQ:EIDXEidos Therapeutics, Inc., a clinical stage biopharmaceutical company, focuses on developing drugs to treat diseases caused by transthyretin (TTR) or amyloidosis (ATTR). It is developing AG10, which is in phase 3 clinical trial, is an orally-administered small molecule designed to stabilize tetrameric TTR, thereby halting at its outset the series of molecular events that give rise to ATTR. The company was founded in 2013 and is headquartered in San Francisco, California. Eidos Therapeutics, Inc. is a subsidiary of BridgeBio Pharma, Inc.Heron Therapeutics NASDAQ:HRTX$1.25 +0.01 (+0.40%) As of 11:11 AM Eastern This is a fair market value price provided by Polygon.io. Learn more.Heron Therapeutics, Inc., a commercial-stage biotechnology company, focuses on enhancing the lives of patients by developing and commercializing therapeutic that enhances medical care. The company's product candidates utilize its proprietary Biochronomer, a drug delivery technology, which delivers therapeutic levels of a range of short-acting pharmacological agents over a period from days to weeks with a single administration. It offers SUSTOL (granisetron), an extended-release injection for the prevention of acute and delayed nausea and vomiting associated with moderately emetogenic chemotherapy, or anthracycline and cyclophosphamide combination chemotherapy regimens; and CINVANTI, an intravenous formulation of aprepitant, a substance P/neurokinin-1 receptor antagonist for the prevention of acute and delayed nausea and vomiting associated with highly emetogenic cancer chemotherapy, as well as nausea and vomiting associated with moderately emetogenic cancer chemotherapy. The company is also developing ZYNRELEF, a dual-acting local anesthetic that delivers a fixed-dose combination of the local anesthetic bupivacaine and a low dose of the nonsteroidal anti-inflammatory drug meloxicam; and APONVIE, an intravenous formulation of a substance P/neurokinin-1 receptor antagonist indicated for the prevention of postoperative nausea and vomiting in adults. The company was formerly known as A.P. Pharma, Inc. and changed its name to Heron Therapeutics, Inc. in January 2014. Heron Therapeutics, Inc. was founded in 1983 and is headquartered in San Diego, California.Ironwood Pharmaceuticals NASDAQ:IRWD$1.31 +0.03 (+2.66%) As of 11:09 AM Eastern This is a fair market value price provided by Polygon.io. Learn more.Ironwood Pharmaceuticals, Inc., a healthcare company, focuses on the development and commercialization of gastrointestinal (GI) products. It markets linaclotide, a guanylate cyclase type-C (GC-C) agonist for the treatment of adults suffering from irritable bowel syndrome with constipation or chronic idiopathic constipation under the LINZESS name in the United States, Mexico, Japan, Saudi Arabia, and China, as well as under the CONSTELLA name in the Canada and European countries. The company is also developing IW-3300, a GC-C agonist for the treatment of visceral pain conditions, including interstitial cystitis/bladder pain syndrome and endometriosis; Apraglutide, a next-generation, long-acting synthetic peptide analog of glucagon-like peptide-2, as a differentiated therapeutic for rare diseases, including short bowel syndrome dependent on parenteral support and acute graft versus host disease; and CNP-104, an immune nanoparticle for the treatment of primary biliary cholangitis. The company has strategic partnerships with AbbVie Inc., AstraZeneca AB, and Astellas Pharma Inc. for the development and commercialization of linaclotide. The company was formerly known as Microbia, Inc. and changed its name to Ironwood Pharmaceuticals, Inc. in April 2008. Ironwood Pharmaceuticals, Inc. was incorporated in 1998 and is headquartered in Boston, Massachusetts.Ligand Pharmaceuticals NASDAQ:LGND$164.80 -0.72 (-0.43%) As of 11:11 AM Eastern This is a fair market value price provided by Polygon.io. Learn more.Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and Evomela, which are used to treat multiple myeloma; Rylaze, a recombinant erwinia asparaginase for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; Filspari, a dual endothelin and angiotensin II receptor antagonist in development for rare kidney diseases and non-immunosuppressive treatment indicated for immunoglobulin A nephropathy; Teriparatide injection product for osteoporosis; Vaxneuvance for the prevention of invasive disease caused by streptococcus pneumoniae serotypes; and Pneumosil, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia among children. The company also offers TZIELD, a CD3-directed antibody indicated to delay the onset of Stage 3 type 1 diabetes (T1D) in adults and children aged 8 years and older with Stage 2 T1D; Nexterone, a captisol-enabled formulation of amiodarone; Zulresso, a captisol-enabled formulation of brexanolone for the treatment of postpartum depression; and Veklury, an antiviral treatment for moderate or severe COVID-19. In addition, it provides Noxafil-IV, a captisol-enabled formulation of posaconazole for IV use; Duavee for the treatment of post-menopausal symptoms in women; Exemptia for autoimmune diseases; Vivitra for breast cancer; and Bryxta and Zybev for various indications. The company has alliances, licenses, and other business relationships with Amgen, Merck, Pfizer, Jazz, Takeda, Gilead Sciences, and Baxter International. Further, it sells Captisol materials. Ligand Pharmaceuticals Incorporated was incorporated in 1987 and is based in Jupiter, Florida. 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