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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
AXSM Axsome Therapeutics	$103.98 -1.0%	$108.00	$64.11 ▼ $139.13	$5.12B	0.46	688,230 shs	441,549 shs
BPMC Blueprint Medicines	$100.06 -1.4%	$91.23	$73.04 ▼ $121.90	$6.56B	0.83	781,125 shs	709,926 shs
MESO Mesoblast	$10.97 +1.1%	$11.46	$5.78 ▼ $22.00	$1.39B	2.5	272,143 shs	301,230 shs
SRPT Sarepta Therapeutics	$38.35 +1.2%	$53.05	$34.10 ▼ $173.25	$3.77B	0.85	1.80 million shs	4.24 million shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
AXSM Axsome Therapeutics	-1.04%	-4.03%	-2.15%	-18.97%	+38.29%
BPMC Blueprint Medicines	-1.42%	-2.85%	+14.15%	+9.47%	-2.67%
MESO Mesoblast	+1.11%	-4.94%	-7.19%	-30.14%	+34.27%
SRPT Sarepta Therapeutics	+1.19%	-4.10%	-36.55%	-64.11%	-68.94%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
AXSM Axsome Therapeutics	4.7356 of 5 stars	4.5	2.0	4.5	2.8	4.2	0.6
BPMC Blueprint Medicines	2.5596 of 5 stars	4.4	1.0	0.0	2.9	0.8	0.6
MESO Mesoblast	1.6995 of 5 stars	3.5	2.0	0.0	1.7	0.8	0.6
SRPT Sarepta Therapeutics	4.7899 of 5 stars	4.4	2.0	4.2	3.2	2.5	1.9

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
AXSM Axsome Therapeutics	3.07	Buy	$172.14	65.55% Upside
BPMC Blueprint Medicines	2.83	Moderate Buy	$126.56	26.49% Upside
MESO Mesoblast	3.00	Buy	$18.00	64.08% Upside
SRPT Sarepta Therapeutics	2.83	Moderate Buy	$122.61	219.71% Upside

Current Analyst Ratings Breakdown

Latest MESO, SRPT, BPMC, and AXSM Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
5/22/2025	AXSM Axsome Therapeutics	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$180.00 ➝ $180.00
5/22/2025	SRPT Sarepta Therapeutics	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Neutral ➝ Neutral	$40.00 ➝ $40.00
5/20/2025	SRPT Sarepta Therapeutics	JPMorgan Chase & Co. Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Overweight ➝ Overweight	$169.00 ➝ $84.00
5/14/2025	AXSM Axsome Therapeutics	Cantor Fitzgerald Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Strong-Buy
5/8/2025	SRPT Sarepta Therapeutics	UBS Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Buy	$188.00 ➝ $85.00
5/8/2025	SRPT Sarepta Therapeutics	Wells Fargo & Company Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Overweight ➝ Overweight	$115.00 ➝ $100.00
5/8/2025	SRPT Sarepta Therapeutics	Evercore ISI Subscribe to MarketBeat All Access for the recommendation accuracy rating	Downgrade	Outperform ➝ Inline	$50.00
5/7/2025	AXSM Axsome Therapeutics	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Buy ➝ Buy	$200.00 ➝ $180.00
5/7/2025	SRPT Sarepta Therapeutics	Royal Bank of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Sector Perform ➝ Sector Perform	$87.00 ➝ $58.00
5/7/2025	SRPT Sarepta Therapeutics	The Goldman Sachs Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Buy ➝ Buy	$178.00 ➝ $100.00
5/7/2025	SRPT Sarepta Therapeutics	Guggenheim Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Buy ➝ Buy	$112.00 ➝ $98.00

(Data available from 5/28/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
AXSM Axsome Therapeutics	$432.16M	11.85	N/A	N/A	$1.18 per share	88.12
BPMC Blueprint Medicines	$562.12M	11.50	N/A	N/A	$4.67 per share	21.43
MESO Mesoblast	$5.67M	247.22	N/A	N/A	$4.21 per share	2.61
SRPT Sarepta Therapeutics	$2.23B	1.69	N/A	N/A	$9.19 per share	4.17

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
AXSM Axsome Therapeutics	-$287.22M	-$5.77	N/A	36.87	N/A	-74.47%	-223.51%	-39.88%	8/4/2025 (Estimated)
BPMC Blueprint Medicines	-$67.09M	-$2.47	N/A	153.94	N/A	-13.19%	-77.49%	-20.84%	8/7/2025 (Estimated)
MESO Mesoblast	-$87.96M	N/A	0.00	N/A	N/A	N/A	N/A	N/A	7/29/2025 (Estimated)
SRPT Sarepta Therapeutics	-$535.98M	-$2.69	30.68	3.51	N/A	7.43%	11.00%	3.35%	8/6/2025 (Estimated)

Latest MESO, SRPT, BPMC, and AXSM Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue	Details
5/6/2025	Q1 2025	SRPT Sarepta Therapeutics	$2.20	-$3.42	-$5.62	-$4.60	$685.75 million	$744.86 million
5/1/2025	Q1 2025	BPMC Blueprint Medicines	-$0.42	-$0.74	-$0.32	$0.01	$158.31 million	$149.41 million

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
AXSM Axsome Therapeutics	N/A	N/A	N/A	N/A	N/A
BPMC Blueprint Medicines	N/A	N/A	N/A	N/A	N/A
MESO Mesoblast	N/A	N/A	N/A	N/A	N/A
SRPT Sarepta Therapeutics	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
AXSM Axsome Therapeutics	3.22	2.11	2.04
BPMC Blueprint Medicines	1.15	2.85	2.80
MESO Mesoblast	0.21	1.18	1.18
SRPT Sarepta Therapeutics	0.93	3.84	3.03

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
AXSM Axsome Therapeutics	81.49%
BPMC Blueprint Medicines	N/A
MESO Mesoblast	1.43%
SRPT Sarepta Therapeutics	86.68%

Insider Ownership

Company	Insider Ownership
AXSM Axsome Therapeutics	22.30%
BPMC Blueprint Medicines	4.21%
MESO Mesoblast	18.80%
SRPT Sarepta Therapeutics	7.70%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
AXSM Axsome Therapeutics	380	49.24 million	37.84 million	Optionable
BPMC Blueprint Medicines	640	64.58 million	61.22 million	Optionable
MESO Mesoblast	80	127.78 million	103.17 million	Optionable
SRPT Sarepta Therapeutics	840	98.28 million	88.17 million	Optionable

MESO, SRPT, BPMC, and AXSM Headlines

Recent News About These Companies

Was Jim Cramer Right About Sarepta Therapeutics Inc. (SRPT)?

May 27 at 10:37 AM | insidermonkey.com

UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC Has $36.39 Million Stock Holdings in Sarepta Therapeutics, Inc. (NASDAQ:SRPT)

May 27 at 4:40 AM | marketbeat.com

Two Sigma Investments LP Has $9.13 Million Holdings in Sarepta Therapeutics, Inc. (NASDAQ:SRPT)

May 27 at 4:27 AM | marketbeat.com

46,986 Shares in Sarepta Therapeutics, Inc. (NASDAQ:SRPT) Purchased by Woodline Partners LP

May 26 at 4:37 AM | marketbeat.com

HC Wainwright Reaffirms "Neutral" Rating for Sarepta Therapeutics (NASDAQ:SRPT)

May 25 at 1:51 AM | americanbankingnews.com

Sarepta Therapeutics (NASDAQ:SRPT) Receives "Neutral" Rating from HC Wainwright

May 24, 2025 | marketbeat.com

Sarepta Therapeutics Analyst Ratings and Price Targets | NASDAQ:SRPT | Benzinga

May 23, 2025 | benzinga.com

Sarepta Therapeutics Analyst Ratings and Price Targets | NASDAQ:SRPT | Benzinga

May 23, 2025 | benzinga.com

Sarepta Therapeutics (NASDAQ:SRPT) Shares Gap Up - Still a Buy?

May 23, 2025 | marketbeat.com

JPMorgan Chase & Co. Cuts Sarepta Therapeutics (NASDAQ:SRPT) Price Target to $84.00

May 23, 2025 | americanbankingnews.com

FDA advisers pan Pfizer’s PARP drug; Sarepta to resume Duchenne study

May 22, 2025 | biopharmadive.com

Sarepta Can Start Dosing Elevidys Trial, UK Regulators Say

May 22, 2025 | precisionmedicineonline.com

Sarepta Therapeutics Stock Gains After U.K. Lets Elevidys Study Continue

May 21, 2025 | marketwatch.com

Sarepta, Roche get U.K. feedback to lift clinical hold on Elevidys' Duchenne trial

May 21, 2025 | msn.com

Sarepta Therapeutics (NasdaqGS:SRPT) Continues Phase 3 Study of ELEVIDYS Gene Therapy in Duchenne

May 21, 2025 | finance.yahoo.com

Sarepta Provides Update on UK Dosing in ENVISION Study of ELEVIDYS for the treatment of Duchenne Muscular Dystrophy

May 21, 2025 | businesswire.com

Vestal Point Capital LP Makes New Investment in Sarepta Therapeutics, Inc. (NASDAQ:SRPT)

May 21, 2025 | marketbeat.com

Triglav Skladi D.O.O. Invests $1.34 Million in Sarepta Therapeutics, Inc. (NASDAQ:SRPT)

May 21, 2025 | marketbeat.com

Nuveen Asset Management LLC Increases Stake in Sarepta Therapeutics, Inc. (NASDAQ:SRPT)

May 21, 2025 | marketbeat.com

Sarepta Shares Higher After J.P. Morgan Note

May 20, 2025 | marketwatch.com

SRPT Q1 Earnings Call: Sarepta Adjusts Guidance After Safety Event and Administrative Delays

May 20, 2025 | msn.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

MESO, SRPT, BPMC, and AXSM Company Descriptions

Axsome Therapeutics NASDAQ:AXSM

$103.98 -1.09 (-1.04%)

Closing price 05/27/2025 04:00 PM Eastern

Extended Trading

$107.30 +3.32 (+3.19%)

As of 05/27/2025 05:15 PM Eastern

Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist with multimodal activity indicated for the treatment of major depressive disorder; and Sunosi (solriamfetol), a medication indicated to the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea. It is also developing AXS-05, which is in Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation; AXS-07, an investigational medicine that has completed Phase III trials for the acute treatment of migraine; AXS-12, an investigational medicine, which is in Phase III trial to treat narcolepsy; AXS-14, a selective and potent norepinephrine reuptake inhibitor that has completed Phase III trial for the treatment of fibromyalgia and other conditions; and solriamfetol, a dual-acting dopamine and norepinephrine reuptake inhibitor, which has completed a Phase 2 trial for treating attention-deficit/hyperactivity disorder, and is in phase 2 major depressive, binge eating, and shift work disorder. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.

Blueprint Medicines NASDAQ:BPMC

$100.06 -1.44 (-1.42%)

Closing price 05/27/2025 04:00 PM Eastern

Extended Trading

$100.08 +0.02 (+0.02%)

As of 05/27/2025 05:50 PM Eastern

Blueprint Medicines Corporation, a precision therapy company, develops medicines for genomically defined cancers and blood disorders in the United States and internationally. The company is developing AYVAKIT for the treatment of systemic mastocytosis (SM) and gastrointestinal stromal tumors; BLU-263, an orally available, potent, and KIT inhibitor for the treatment of indolent SM, and other mast cell disorders. It is also developing GAVRETO for the treatment of RET fusion-positive non-small cell lung cancer, altered thyroid carcinoma, and medullary thyroid carcinoma; BLU-945 for the treatment of epidermal growth factor receptor driven non-small-cell lung carcinoma (NSCLC); and BLU-451 to treat NSCLC in patients with epidermal growth factor receptor gene (EGFR) exon 20 insertion mutations. In addition, the company is developing BLU-782, for the treatment of fibrodysplasia ossificans progressive; BLU- 222 to treat patients with cyclin E aberrant cancers; and BLU-852 for the treatment of advanced cancers. It has collaboration and license agreements with Clementia Pharmaceuticals, Inc.; Proteovant Therapeutics; CStone Pharmaceuticals; Genentech, Inc.; Hoffmann-La Roche Inc.; and Zai Lab (Shanghai) Co., Ltd. The company was formerly known as Hoyle Pharmaceuticals, Inc. and changed its name to Blueprint Medicines Corporation in June 2011. Blueprint Medicines Corporation was incorporated in 2008 and is headquartered in Cambridge, Massachusetts.

Mesoblast NASDAQ:MESO

$10.97 +0.12 (+1.11%)

Closing price 05/27/2025 04:00 PM Eastern

Extended Trading

$11.00 +0.03 (+0.27%)

As of 05/27/2025 07:55 PM Eastern

Mesoblast Limited engages in the development of regenerative medicine products in Australia, the United States, Singapore, and Switzerland. The company offers products in the areas of cardiovascular, spine orthopedic disorder, oncology, hematology, and immune-mediated and inflammatory diseases. Its proprietary regenerative medicine technology platform is based on specialized cells known as mesenchymal lineage cells. The company offers Remestemcel-L that is in Phase III clinical trials for the treatment of systemic inflammatory diseases, including steroid refractory acute graft versus host disease, acute respiratory distress syndrome, and biologic refractory inflammatory bowel disease; and Remestemcel-L, which is in Phase III clinical trials to treat chronic heart failure and chronic low back pain due to degenerative disc disease. It is also developing MPC-300-IV to treat biologic refractory rheumatoid arthritis diabetic nephropathy; and MPC-25-IC for the treatment or prevention of acute myocardial infarction. It has strategic partnerships with Tasly Pharmaceutical Group to offer MPC-150-IM for heart failure and MPC-25-IC for heart attacks in China; JCR Pharmaceuticals Co. Ltd. to treat wound healing in patients with epidermolysis bullosa; and Grünenthal to develops and commercializes cell therapy for the treatment of chronic low back pain. The company was incorporated in 2004 and is headquartered in Melbourne, Australia.

Sarepta Therapeutics NASDAQ:SRPT

$38.35 +0.45 (+1.19%)

Closing price 05/27/2025 04:00 PM Eastern

Extended Trading

$38.58 +0.23 (+0.59%)

As of 05/27/2025 07:59 PM Eastern

Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, gene therapies, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 injection to treat duchenne muscular dystrophy (duchenne) in patients with confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; VYONDYS 53 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping; AMONDYS 45 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene; and ELEVIDYS, an adeno-associated virus based gene therapy for the treatment of ambulatory pediatric patients aged 4 through 5 years with duchenne with a confirmed mutation in the duchenne gene. The company is also developing SRP-5051, a peptide conjugated PMO that binds exon 51 of dystrophin pre-mRNA; and SRP-9003, a limb-girdle muscular dystrophies gene therapy program. It has collaboration and license agreements with F. Hoffman-La Roche Ltd; Nationwide Children's Hospital; Genevant Sciences; University of Florida; Dyno Therapeutics; Hansa Biopharma; Duke University; Genethon; and StrideBio. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.

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Comparative Price Performance Over Time