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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
$0.74
-0.8%
$0.88
$0.66
$3.02
$33.49M2.851.09 million shs623,818 shs
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
$2.63
-5.4%
$2.30
$1.30
$7.37
$10M0.15164,178 shs155,805 shs
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
$2.83
+4.4%
$2.40
$1.70
$20.00
$36.61M0.4131,212 shs59,581 shs
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
$0.70
+4.9%
$0.69
$0.62
$1.70
$34.72M-0.15421,246 shs361,509 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
-0.80%-13.80%-10.36%-20.15%-42.77%
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
-5.40%+4.78%+19.55%+42.16%+1,326.25%
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
+4.43%+11.86%+18.91%+31.63%+282,999,900.00%
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
+4.94%-0.83%+1.97%-20.45%-21.00%
CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
1.8782 of 5 stars
3.53.00.00.00.61.70.0
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
N/AN/AN/AN/AN/AN/AN/AN/A
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
3.1862 of 5 stars
3.60.00.00.02.72.51.3
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
2.7284 of 5 stars
3.72.00.00.01.92.50.6
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
3.00
Buy$9.001,109.68% Upside
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
0.00
N/AN/AN/A
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
3.14
Buy$32.331,042.52% Upside
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
3.33
Buy$3.00326.68% Upside

Current Analyst Ratings Breakdown

Latest NLSP, ITRM, OKUR, and XLO Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
8/13/2025
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
Zacks Research
Subscribe to MarketBeat All Access for the recommendation accuracy rating
DowngradeStrong-Buy ➝ Hold
8/6/2025
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
Leerink Partnrs
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeStrong-Buy
8/6/2025
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
Leerink Partners
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$2.00
(Data available from 8/23/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
N/AN/AN/AN/A($0.09) per shareN/A
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
N/AN/AN/AN/A($0.37) per shareN/A
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
N/AN/AN/AN/A$5.79 per shareN/A
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
$6.34M5.75N/AN/A$0.14 per share5.02
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
-$24.77M-$0.85N/AN/AN/AN/A-65.01%N/A
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
-$1.98MN/A0.00N/AN/AN/AN/AN/A
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
-$52.67M-$4.80N/AN/AN/AN/A-60.52%-55.43%11/6/2025 (Estimated)
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
-$58.24M-$0.76N/AN/AN/A-374.79%-399.15%-58.68%11/6/2025 (Estimated)

Latest NLSP, ITRM, OKUR, and XLO Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
8/14/2025Q2 2025
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
-$0.08-$0.16-$0.08-$0.16$8.21 million$8.21 million
8/12/2025Q2 2025
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
-$1.23-$1.14+$0.09-$1.14N/AN/A
8/5/2025Q2 2025
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
-$0.13-$0.16-$0.03-$0.16N/AN/A
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
N/AN/AN/AN/AN/A
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
N/AN/AN/AN/AN/A
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
N/AN/AN/AN/AN/A
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
N/A
2.69
2.52
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
N/A
2.69
2.69
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
N/A
11.13
11.13
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
N/A
2.32
1.96

Institutional Ownership

CompanyInstitutional Ownership
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
9.21%
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
N/A
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
90.98%
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
54.29%

Insider Ownership

CompanyInsider Ownership
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
2.40%
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
16.40%
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
2.30%
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
5.20%
CompanyEmployeesShares OutstandingFree FloatOptionable
Iterum Therapeutics PLC stock logo
ITRM
Iterum Therapeutics
1044.66 million43.59 millionNot Optionable
NLS Pharmaceutics Ltd. stock logo
NLSP
NLS Pharmaceutics
63.60 million3.01 millionNot Optionable
OnKure Therapeutics, Inc. stock logo
OKUR
OnKure Therapeutics
N/A13.51 million13.20 millionN/A
Xilio Therapeutics, Inc. stock logo
XLO
Xilio Therapeutics
7051.83 million49.13 millionNot Optionable

Recent News About These Companies

Leerink Partnrs Brokers Decrease Earnings Estimates for XLO
Xilio Revenue Jumps 246 Percent in Q2

New MarketBeat Followers Over Time

Media Sentiment Over Time

Iterum Therapeutics stock logo

Iterum Therapeutics NASDAQ:ITRM

$0.74 -0.01 (-0.80%)
Closing price 08/22/2025 04:00 PM Eastern
Extended Trading
$0.76 +0.02 (+2.42%)
As of 08/22/2025 07:52 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Iterum Therapeutics plc, a clinical-stage pharmaceutical company, engages in developing and commercializing anti-infectives in Ireland, Bermuda, and the United States. It is developing sulopenem, a novel anti-infective compound with oral and intravenous formulations that is in Phase III clinical trials for the treatment of uncomplicated urinary tract infections, complicated urinary tract infections, and complicated intra-abdominal infections. The company was incorporated in 2015 and is headquartered in Dublin, Ireland.

NLS Pharmaceutics stock logo

NLS Pharmaceutics NASDAQ:NLSP

$2.63 -0.15 (-5.40%)
Closing price 08/22/2025 04:00 PM Eastern
Extended Trading
$2.65 +0.02 (+0.76%)
As of 08/22/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

NLS Pharmaceutics AG, a clinical-stage biopharmaceutical company, engages in the discovery and development of therapies for patients with rare and complex central nervous system disorders. The company is focusing on the development of treatments for narcolepsy, idiopathic hypersomnia, and other rare sleep disorders, as well as neurodevelopmental disorders, such as attention deficit hyperactivity disorder (ADHD). Its lead product candidates include Quilience to treat excessive daytime sleepiness and cataplexy; and Nolazol for the treatment of ADHD. The company also developing NLS-4, a selective dopamine reuptake inhibitor to prevent rare sleep disorders; NLS-3, a repurposed reverse ester of methylphenidate for treatment of ADHD; NLS-8, a melatonin ML1A receptor agonist, improved scopolamine-induced amnesia; NLS-11, a norepinephrine and dopamine reuptake inhibitor and muscarinic M1, M2, M3 receptor antagonist; and NLS-12, a norepinephrine and dopamine reuptake inhibitor and muscarinic M4 receptor antagonist. NLS Pharmaceutics AG was incorporated in 2015 and is based in Zurich, Switzerland.

OnKure Therapeutics stock logo

OnKure Therapeutics NASDAQ:OKUR

$2.83 +0.12 (+4.43%)
Closing price 08/22/2025 04:00 PM Eastern
Extended Trading
$2.82 -0.01 (-0.35%)
As of 08/22/2025 07:57 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

OnKure Therapeutics, Inc. engages in discovering and developing precision medicines that target biologically validated drivers of cancers underserved by available therapies. The company uses a structure and computational chemistry driven drug design platform, committed to improving clinical outcomes for patients by building a robust pipeline of small molecule drugs designed to selectively target specific mutations thought to be key drivers of cancer. It is headquartered in Boulder, CO.

Xilio Therapeutics stock logo

Xilio Therapeutics NASDAQ:XLO

$0.70 +0.03 (+4.94%)
Closing price 08/22/2025 04:00 PM Eastern
Extended Trading
$0.70 -0.01 (-0.73%)
As of 08/22/2025 07:57 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of tumor-activated immuno-oncology therapies. The company's checkpoint inhibitor program includes XTX101, an investigational Fc-enhanced, tumor-activated anti-CTLA-4 mAb that is in Phase 2 clinical trial for patients with advanced solid tumors. It also develops cytokine programs, which comprises XTX202, a tumor-activated beta-gamma biased IL-2, currently under Phase 2 clinal trials; and XTX301, an investigational tumor-activated, engineered IL-12 molecule, currently under Phase 1 studies. The company was founded in 2016 and is headquartered in Waltham, Massachusetts.