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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ATAINASDAQ:ATYRNASDAQ:PVLANASDAQ:SGMT On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeATAIatai Life Sciences$2.48+6.4%$1.85$1.03▼$2.64$466.79M1.481.72 million shs3.94 million shsATYRaTyr Pharma$5.22+1.0%$3.99$1.42▼$5.98$460.15M0.881.08 million shs3.32 million shsPVLAPalvella Therapeutics$22.05+7.5%$23.80$6.20▼$29.27$226.75M-0.176,153 shs81,392 shsSGMTSagimet Biosciences$8.72+23.9%$4.06$1.73▼$9.60$215.95M2.211.06 million shs2.01 million shsReduce the RiskMarket downturns give many investors pause, and for good reason. Wondering how to offset this risk? Enter your email address to learn more about using beta to protect your portfolio.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceATAIatai Life Sciences0.00%+6.88%+13.66%+60.69%+83.46%ATYRaTyr Pharma0.00%-4.79%+48.14%+40.49%+516,999,900.00%PVLAPalvella Therapeutics0.00%-22.37%-11.71%-27.11%+2,050,999,900.00%SGMTSagimet Biosciences0.00%-18.23%+105.25%+76.44%+78.23%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationATAIatai Life Sciences3.0152 of 5 stars3.73.00.00.02.42.50.6ATYRaTyr Pharma2.6356 of 5 stars3.61.00.00.04.11.70.6PVLAPalvella Therapeutics3.9058 of 5 stars4.60.00.00.02.54.20.6SGMTSagimet Biosciences1.7916 of 5 stars3.42.00.00.01.12.50.0Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceATAIatai Life Sciences 3.33Buy$8.67249.46% UpsideATYRaTyr Pharma 3.14Buy$20.20286.97% UpsidePVLAPalvella Therapeutics 3.13Buy$46.29109.91% UpsideSGMTSagimet Biosciences 2.83Moderate Buy$23.17165.67% UpsideCurrent Analyst Ratings BreakdownLatest SGMT, ATYR, ATAI, and PVLA Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails6/20/2025ATYRaTyr PharmaWells Fargo & CompanySubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOverweight ➝ Overweight$17.00 ➝ $25.006/6/2025SGMTSagimet BiosciencesJones TradingSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$15.00 ➝ $27.006/4/2025ATYRaTyr PharmaHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$35.005/20/2025ATAIatai Life SciencesJefferies Financial GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingSet Price Target$5.005/20/2025ATAIatai Life SciencesHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$10.00 ➝ $10.005/19/2025ATYRaTyr PharmaHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$35.00 ➝ $35.005/16/2025PVLAPalvella TherapeuticsCanaccord Genuity GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$53.00 ➝ $52.005/13/2025ATAIatai Life SciencesCantor FitzgeraldSubscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeStrong-Buy4/30/2025PVLAPalvella TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$38.00 ➝ $38.004/9/2025PVLAPalvella TherapeuticsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageBuy$50.004/1/2025PVLAPalvella TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$38.00 ➝ $38.00(Data available from 6/20/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookATAIatai Life Sciences$310K1,602.72N/AN/A$0.69 per share3.59ATYRaTyr Pharma$230K2,019.91N/AN/A$0.83 per share6.29PVLAPalvella Therapeutics$42.81M5.70N/AN/A$5.58 per share3.95SGMTSagimet Biosciences$2M133.72N/AN/A$5.08 per share1.72Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateATAIatai Life Sciences-$149.27M-$0.91N/AN/AN/AN/A-102.10%-77.55%8/12/2025 (Estimated)ATYRaTyr Pharma-$64.02M-$0.81N/AN/AN/AN/A-87.09%-64.77%8/12/2025 (Estimated)PVLAPalvella Therapeutics-$17.43M-$12.10N/AN/AN/AN/A-60.29%-43.30%8/13/2025 (Estimated)SGMTSagimet Biosciences-$45.57M-$1.76N/AN/AN/AN/A-35.21%-34.09%8/13/2025 (Estimated)Latest SGMT, ATYR, ATAI, and PVLA EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/15/2025Q1 2025PVLAPalvella Therapeutics-$3.40-$0.74+$2.66-$0.74N/AN/A5/14/2025Q1 2025ATAIatai Life Sciences-$0.19-$0.15+$0.04-$0.15N/A$1.56 million5/8/2025Q1 2025SGMTSagimet Biosciences-$0.79-$0.56+$0.23-$0.56N/AN/A5/7/2025Q1 2025ATYRaTyr Pharma-$0.19-$0.17+$0.02-$0.17N/AN/ACompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthATAIatai Life SciencesN/AN/AN/AN/AN/AATYRaTyr PharmaN/AN/AN/AN/AN/APVLAPalvella TherapeuticsN/AN/AN/AN/AN/ASGMTSagimet BiosciencesN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioATAIatai Life Sciences0.084.074.07ATYRaTyr Pharma0.017.797.79PVLAPalvella TherapeuticsN/A8.848.84SGMTSagimet BiosciencesN/A20.3420.34Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipATAIatai Life Sciences28.41%ATYRaTyr Pharma61.72%PVLAPalvella Therapeutics40.11%SGMTSagimet Biosciences87.86%Insider OwnershipCompanyInsider OwnershipATAIatai Life Sciences26.80%ATYRaTyr Pharma3.70%PVLAPalvella Therapeutics20.50%SGMTSagimet Biosciences14.70%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableATAIatai Life Sciences80200.34 million146.65 millionOptionableATYRaTyr Pharma5389.00 million85.71 millionOptionablePVLAPalvella TherapeuticsN/A11.06 million8.79 millionN/ASGMTSagimet Biosciences830.67 million26.17 millionOptionableSGMT, ATYR, ATAI, and PVLA HeadlinesRecent News About These CompaniesSagimet Biosciences Inc.June 14, 2025 | wsj.comTwo Sigma Investments LP Trims Holdings in Sagimet Biosciences Inc. (NASDAQ:SGMT)June 12, 2025 | marketbeat.comSagimet Biosciences updates executive compensationJune 12, 2025 | investing.comWhat Makes Sagimet Biosciences Inc. (SGMT) a Strong Momentum Stock: Buy Now?June 11, 2025 | zacks.comAnalysts Set Sagimet Biosciences Inc. (NASDAQ:SGMT) Price Target at $23.17June 11, 2025 | americanbankingnews.comSagimet Biosciences to Host Virtual KOL Event, “A New Mechanism of Action in Treating Acne: Update on Positive Phase 3 Denifanstat Trial for the Treatment of Moderate to ...June 11, 2025 | morningstar.comWall Street Analysts Predict a 437.05% Upside in Sagimet Biosciences Inc. (SGMT): Here's What You Should KnowJune 9, 2025 | zacks.comSagimet Biosciences to Host Virtual KOL Event, “A New Mechanism of Action in Treating Acne: Update on Positive Phase 3 Denifanstat Trial for the Treatment of Moderate to Severe Acne” on June 16, 2025June 9, 2025 | globenewswire.comSagimet Biosciences Inc. (NASDAQ:SGMT) Receives Average Recommendation of "Moderate Buy" from BrokeragesJune 6, 2025 | marketbeat.comSagimet Biosciences (NASDAQ:SGMT) Price Target Raised to $27.00 at Jones TradingJune 6, 2025 | marketbeat.comSagimet Biosciences Analyst RatingsJune 5, 2025 | benzinga.comSagimet Biosciences Shares Climb on Positive Clinical Trial Results for Acne TreatmentJune 4, 2025 | marketwatch.comSagimet Biosciences shares soar on positive acne treatment trial resultsJune 4, 2025 | ca.investing.comSagimet partner Ascletis announces significant Phase III acne dataJune 4, 2025 | thepharmaletter.comSagimet Biosciences Shares Surge After Promising Phase 3 Acne Drug ResultsJune 4, 2025 | msn.comSagimet climbs as acne therapy hits main goals in late-stage trial in ChinaJune 4, 2025 | msn.comSagimet's Partner Achieves Positive Results With Oral Acne Drug In Phase 3 Trial In China, Stock JumpsJune 4, 2025 | aol.comSagimet: Positive China Partner Acne Vulgaris Data Bodes Well For TVB-3567June 4, 2025 | seekingalpha.comSagimet Biosciences Announces Positive Phase 3 Results for Denifanstat for the Treatment of Moderate-to-Severe Acne from Partner AscletisJune 4, 2025 | globenewswire.comMillennium Management LLC Buys 499,094 Shares of Sagimet Biosciences Inc. (NASDAQ:SGMT)June 1, 2025 | marketbeat.comSagimet Biosciences’ SWOT analysis: denifanstat’s potential in MASH treatmentMay 24, 2025 | investing.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeSGMT, ATYR, ATAI, and PVLA Company Descriptionsatai Life Sciences NASDAQ:ATAI$2.48 +0.15 (+6.44%) Closing price 04:00 PM EasternExtended Trading$2.48 +0.00 (+0.16%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Atai Life Sciences N.V., a clinical-stage biopharmaceutical company, develops and invests in various therapeutics to treat depression, anxiety, addiction, and other mental health disorders. Its product candidates include COMP360, a proprietary psilocybin which is in Phase 3 program; BPL-003, an intranasal formulation that is in Phase 2a and 2b clinical studies; TRD; VLS-01, an transmucosal film in Phase 1b clinical studies; and ELE-101, a serotonergic psychedelic that is in Phase 1/2a study, for the treatment of treatment resistant depression. The company also develop IBX-210, an intravenous formulation of ibogaine, and DMX-1002, an oral formulation of ibogaine indicated for the treatment of opioid use disorder; EMP-01, an oral formulation of an R-MDMA derivative being developed for the treatment of post-traumatic stress disorder; and EGX-A and EGX-B, psychedelic-like with novel, non-tryptamine structures with differentiated 5-HT receptor pharmacology. In addition, it offers RL-007, an orally bioavailable compound, which is a pro-cognitive neuromodulator for cognitive impairment associated with schizophrenia; and GRX-917, a deuterated etifoxine for the treatment of generalize anxiety disorder. Further, the company develops PCN-101, a subcutaneous formulation of R-ketamine, as a therapy for psychiatric indications initially focused on TRD; KUR-101, a formulation of deuterated mitragynine for the treatment of OUD; and RLS-01, indicated for treatment resistant depression. ATAI Life Sciences N.V. was founded in 2018 and is headquartered in Berlin, Germany with offices in New York and London.aTyr Pharma NASDAQ:ATYR$5.22 +0.05 (+0.97%) Closing price 04:00 PM EasternExtended Trading$5.26 +0.04 (+0.86%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.aTyr Pharma, Inc. engages in the discovery and development of medicines based on novel biological pathways. Its product pipeline includes ATYR1923, ATYR2810, NRP2 mAbs, and AARS-1, DARS-1. The company was founded by Paul Schimmel, Xiang-Lei Yang and Bruce Beutler on September 8, 2005 and is headquartered in San Diego, CA.Palvella Therapeutics NASDAQ:PVLA$22.05 +1.54 (+7.51%) As of 04:00 PM EasternPalvella Therapeutics Inc. is a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapies to treat patients suffering from serious, rare genetic skin diseases. Palvella Therapeutics Inc., formerly known as Pieris Pharmaceuticals Inc., is based in WAYNE, Pa.Sagimet Biosciences NASDAQ:SGMT$8.72 +1.68 (+23.86%) Closing price 04:00 PM EasternExtended Trading$8.65 -0.07 (-0.75%) As of 07:56 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Sagimet Biosciences Inc., a clinical-stage biopharmaceutical company, develops therapeutics called fatty acid synthase (FASN) inhibitors for the treatment of diseases that result from dysfunctional metabolic pathways in the United States. The company's lead drug candidate is Denifanstat, a once-daily pill and selective FASN inhibitor for the treatment of metabolic dysfunction associated steatohepatitis. It also develops TVB-3567, a FASN inhibitor for the treatment of acne; and other oncology programs. The company was formerly known as 3-V Biosciences, Inc. and changed its name to Sagimet Biosciences Inc. in August 2019. Sagimet Biosciences Inc. was incorporated in 2006 and is headquartered in San Mateo, California. 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