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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:IOVA NASDAQ:PHAR NASDAQ:SOPH NASDAQ:TRVI On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeIOVAIovance Biotherapeutics$2.42-1.2%$2.33$1.64▼$12.51$886.54M0.8815.98 million shs9.10 million shsPHARPharming Group$13.97+4.3%$11.15$6.73▼$17.08$918.17M0.0214,522 shs4,343 shsSOPHSOPHiA GENETICS$3.33-1.5%$3.33$2.58▼$4.92$228.42M196,623 shs42,811 shsTRVITrevi Therapeutics$8.00+7.8%$6.87$2.36▼$8.78$903.58M0.581.42 million shs9.49 million shsAnalysts Agree—These Gold Picks Outshine the RestUnlock the timeless value of gold with our exclusive 2025 Gold Forecasting Report. Explore why gold remains the ultimate investment for safeguarding wealth against inflation, economic shifts, and global uncertainties. Whether you're planning for future generations or seeking a reliable asset in turbulent times, this report is your essential guide to making informed decisions.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceIOVAIovance Biotherapeutics-1.22%-4.35%-17.97%+32.24%-78.77%PHARPharming Group+3.07%+14.32%+39.70%+31.79%+72.04%SOPHSOPHiA GENETICS-1.48%-6.98%-0.89%+16.03%-7.76%TRVITrevi Therapeutics+7.82%+7.82%+4.71%+25.79%+174.91%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationIOVAIovance Biotherapeutics4.6098 of 5 stars4.24.00.04.21.62.50.6PHARPharming Group2.3774 of 5 stars3.53.00.00.03.00.00.6SOPHSOPHiA GENETICS2.7423 of 5 stars3.55.00.00.02.10.00.6TRVITrevi Therapeutics2.7032 of 5 stars4.61.00.00.01.52.50.0Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceIOVAIovance Biotherapeutics 2.36Hold$11.90391.74% UpsidePHARPharming Group 3.00Buy$30.00114.75% UpsideSOPHSOPHiA GENETICS 3.00Buy$8.00140.24% UpsideTRVITrevi Therapeutics 3.20Buy$20.11151.39% UpsideCurrent Analyst Ratings BreakdownLatest SOPH, PHAR, IOVA, and TRVI Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails8/21/2025TRVITrevi TherapeuticsMorgan StanleySubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$18.008/19/2025IOVAIovance BiotherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$20.008/12/2025IOVAIovance BiotherapeuticsZacks ResearchSubscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeHold8/8/2025IOVAIovance BiotherapeuticsWells Fargo & CompanySubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOverweight ➝ Overweight$18.00 ➝ $14.008/8/2025IOVAIovance BiotherapeuticsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$25.00 ➝ $20.008/8/2025TRVITrevi TherapeuticsRaymond James FinancialSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetStrong-Buy ➝ Strong-Buy$29.00 ➝ $27.008/8/2025TRVITrevi TherapeuticsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$24.00 ➝ $22.007/23/2025IOVAIovance BiotherapeuticsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$25.007/15/2025IOVAIovance BiotherapeuticsThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingDowngradeNeutral ➝ Sell7/1/2025TRVITrevi TherapeuticsCantor FitzgeraldSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$25.006/2/2025TRVITrevi TherapeuticsOppenheimerSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform(Data available from 8/28/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookIOVAIovance Biotherapeutics$164.07M5.34N/AN/A$1.93 per share1.25PHARPharming Group$297.20M3.22$0.08 per share180.78$3.50 per share3.99SOPHSOPHiA GENETICS$65.17M3.45N/AN/A$1.13 per share2.95TRVITrevi TherapeuticsN/AN/AN/AN/A$1.63 per shareN/ACompare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateIOVAIovance Biotherapeutics-$372.18M-$1.23N/AN/AN/A-161.44%-52.87%-41.31%11/6/2025 (Estimated)PHARPharming Group-$11.84M-$0.13N/A465.67N/A-2.19%-3.31%-1.78%10/23/2025 (Estimated)SOPHSOPHiA GENETICS-$62.49M-$0.44N/AN/AN/A-40.99%-30.69%-17.39%11/4/2025 (Estimated)TRVITrevi Therapeutics-$47.91M-$0.42N/AN/AN/AN/A-41.44%-38.21%11/5/2025 (Estimated)Latest SOPH, PHAR, IOVA, and TRVI EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/7/2025Q2 2025IOVAIovance Biotherapeutics-$0.29-$0.33-$0.04-$0.33$67.14 million$59.95 million8/7/2025Q2 2025TRVITrevi Therapeutics-$0.10-$0.09+$0.01-$0.09N/AN/A8/5/2025Q2 2025SOPHSOPHiA GENETICS-$0.25$0.33+$0.58$0.33$17.49 million$18.32 million7/31/2025Q2 2025PHARPharming Group-$0.10$0.06+$0.16$0.06$70.36 million$93.20 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthIOVAIovance BiotherapeuticsN/AN/AN/AN/AN/APHARPharming GroupN/AN/AN/AN/AN/ASOPHSOPHiA GENETICSN/AN/AN/AN/AN/ATRVITrevi TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioIOVAIovance BiotherapeuticsN/A3.272.89PHARPharming Group0.382.792.07SOPHSOPHiA GENETICS0.623.393.21TRVITrevi TherapeuticsN/A22.4222.42Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipIOVAIovance Biotherapeutics77.03%PHARPharming Group0.03%SOPHSOPHiA GENETICS31.59%TRVITrevi Therapeutics95.76%Insider OwnershipCompanyInsider OwnershipIOVAIovance Biotherapeutics10.30%PHARPharming Group2.07%SOPHSOPHiA GENETICS4.88%TRVITrevi Therapeutics18.30%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableIOVAIovance Biotherapeutics500361.85 million324.58 millionOptionablePHARPharming Group28068.51 million67.10 millionNot OptionableSOPHSOPHiA GENETICS52067.58 million64.28 millionNot OptionableTRVITrevi Therapeutics20121.78 million99.49 millionOptionableSOPH, PHAR, IOVA, and TRVI HeadlinesRecent News About These CompaniesTrevi Therapeutics to Participate in Upcoming September Conferences1 hour ago | prnewswire.comTrevi Therapeutics (NASDAQ:TRVI) Now Covered by Morgan StanleyAugust 24, 2025 | americanbankingnews.comTrevi Therapeutics (NASDAQ:TRVI) Coverage Initiated by Analysts at Morgan StanleyAugust 23, 2025 | marketbeat.comMorgan Stanley Initiates Coverage of Trevi Therapeutics (TRVI) with Overweight RecommendationAugust 22, 2025 | msn.comTrevi Therapeutics, Inc. (NASDAQ:TRVI) Receives $20.38 Average Price Target from AnalystsAugust 20, 2025 | americanbankingnews.comB. Riley Boosts Earnings Estimates for Trevi TherapeuticsAugust 19, 2025 | marketbeat.comB. Riley Increases Earnings Estimates for Trevi TherapeuticsAugust 19, 2025 | americanbankingnews.comTrevi Therapeutics, Inc. (NASDAQ:TRVI) Shares Sold by XTX Topco LtdAugust 17, 2025 | marketbeat.comTrevi Therapeutics, Inc. (NASDAQ:TRVI) Receives Consensus Rating of "Buy" from AnalystsAugust 16, 2025 | marketbeat.comPersistent Asset Partners Ltd Makes New $260,000 Investment in Trevi Therapeutics, Inc. (NASDAQ:TRVI)August 13, 2025 | marketbeat.comInformed Momentum Co LLC Invests $3.47 Million in Trevi Therapeutics, Inc. (NASDAQ:TRVI)August 13, 2025 | marketbeat.comAnalysts Offer Insights on Healthcare Companies: Trevi Therapeutics (TRVI), DENTSPLY SIRONA (XRAY) and Arrowhead Pharmaceuticals (ARWR)August 13, 2025 | theglobeandmail.comTrevi Therapeutics: Optimism Amid Earnings Call InsightsAugust 13, 2025 | msn.comHC Wainwright Analysts Increase Earnings Estimates for TRVIAugust 12, 2025 | marketbeat.comTrevi Therapeutics (NASDAQ:TRVI) Posts Quarterly Earnings Results, Beats Estimates By $0.01 EPSAugust 11, 2025 | marketbeat.comRaymond James Financial Issues Pessimistic Forecast for Trevi Therapeutics (NASDAQ:TRVI) Stock PriceAugust 10, 2025 | marketbeat.comTrevi Therapeutics (NASDAQ:TRVI) Is In A Good Position To Deliver On Growth PlansAugust 10, 2025 | finance.yahoo.comNeedham & Company LLC Lowers Trevi Therapeutics (NASDAQ:TRVI) Price Target to $22.00August 9, 2025 | marketbeat.comTrevi Therapeutics, Inc. (TRVI) Q2 2025 Earnings Call TranscriptAugust 8, 2025 | seekingalpha.comTrevi Therapeutics Reports Second Quarter 2025 Financial Results and Provides Business UpdatesAugust 7, 2025 | prnewswire.com41,987 Shares in Trevi Therapeutics, Inc. (NASDAQ:TRVI) Bought by BIT Capital GmbHAugust 4, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over Time Top HeadlinesView All HeadlinesBuffett Makes Big Moves Outside of UNH: A Buy and Sell BreakdownBy Leo Miller | August 18, 20253 Companies That Will Profit From Trump's Semiconductor TariffsBy Jordan Chussler | August 14, 2025Trump GLP-1 Pilot Program Could Boost Novo Nordisk & Eli LillyBy Jordan Chussler | August 9, 20253 Biotech Catalysts Present Major OpportunityBy Nathan Reiff | August 25, 2025JNJ Stock Surge Signals Confidence in New Growth PathBy Jeffrey Neal Johnson | August 25, 2025SOPH, PHAR, IOVA, and TRVI Company DescriptionsIovance Biotherapeutics NASDAQ:IOVA$2.42 -0.03 (-1.22%) Closing price 08/27/2025 04:00 PM EasternExtended Trading$2.42 0.00 (0.00%) As of 07:25 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Iovance Biotherapeutics, Inc., a commercial-stage biotechnology company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States. The company offers Amtagvi, a tumor-derived autologous T cell immunotherapy used to treat adult patients with unresectable or metastatic melanoma; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic renal cell carcinoma. It also develops lifileucel in combination with pembrolizumab to treat frontline advanced melanoma patients; LN-145 for the treatment of non-small cell lung cancer (NSCLC) and solid tumor cancers; IOV-4001, which is in Phase 1/2 IOV-GM1-201 clinical trial, for the treatment of NSCLC; and lifileucel for gynecological cancers. The company has collaborations and licensing agreements with WuXi Advanced Therapies, Inc.; National Institutes of Health; the National Cancer Institute; H. Lee Moffitt Cancer Center; The University of Texas M.D. Anderson Cancer Center; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.Pharming Group NASDAQ:PHAR$13.97 +0.57 (+4.25%) Closing price 08/27/2025 03:46 PM EasternExtended Trading$14.31 +0.34 (+2.43%) As of 07:48 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Pharming Group N.V., a biopharmaceutical company, develops and commercializes protein replacement therapies and precision medicines for the treatment of rare diseases in the United States, Europe, and internationally. The company offers RUCONEST, a recombinant C1 esterase inhibitor for the treatment of acute attacks in adult and adolescent patients with acute hereditary angioedema (HAE); and Joenja (leniolisib), an oral small molecule PI3K? inhibitor for the treatment of activated phosphoinositide 3-kinase delta syndrome. It also develops OTL-105, an investigational ex-vivo autologous hematopoietic stem cell gene therapy for the treatment of HAE. The company has a development collaboration and license agreement with Novartis; and a strategic collaboration agreement with Orchard Therapeutics plc for research, development, manufacturing, and commercialization of OTL-105. Pharming Group N.V. was incorporated in 1988 and is headquartered in Leiden, the Netherlands.SOPHiA GENETICS NASDAQ:SOPH$3.33 -0.05 (-1.48%) Closing price 08/27/2025 04:00 PM EasternExtended Trading$3.34 +0.02 (+0.45%) As of 08/27/2025 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.SOPHiA GENETICS SA operates as a cloud-native software technology company in the healthcare space. The company offers SOPHiA DDM platform, a cloud-native software platform for analyzing data and generating insights from multimodal data sets and diagnostic modalities. Its SOPHiA DDM platform and related solutions, applications, products, and services are used by hospitals, laboratories, and biopharmaceutical companies through its own sales force as well as distributors and industry collaborators in Switzerland, France, Italy, rest of Europe, North America, the United States, Latin America, and the Asia-pacific. SOPHiA GENETICS SA was incorporated in 2011 and is headquartered in Rolle, Switzerland.Trevi Therapeutics NASDAQ:TRVI$8.00 +0.58 (+7.82%) Closing price 08/27/2025 04:00 PM EasternExtended Trading$8.15 +0.15 (+1.94%) As of 07:52 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Trevi Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapy Haduvio for the treatment of chronic cough in idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC) conditions targeting the central and peripheral nervous systems. The company is developing Haduvio, an oral extended-release formulation of nalbuphine, which is in phase 2b Cough Reduction in IPF with nalbuphine ER (CORAL) clinical trial for treatment of chronic cough in patients with IPF; phase 2a Refractory Chronic Cough Improvement Via NAL ER (RIVER) clinical trial for reducing chronic cough in RCC patients; phase 2 clinical trial in patients with pruritus; phase 2b/3 clinical trial in patients with prurigo nodularis. It has a license agreement with Endo Pharmaceuticals Inc. to develop and commercialize products incorporating nalbuphine hydrochloride in any formulation. The company was incorporated in 2011 and is headquartered in New Haven, Connecticut. 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