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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ARCTNASDAQ:ORKANASDAQ:SLDBNASDAQ:VIGL On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeARCTArcturus Therapeutics$11.24-5.3%$11.69$8.04▼$45.00$303.92M2.36450,897 shs83,313 shsORKAOruka Therapeutics$9.43-2.0%$9.93$5.49▼$31.13$352.84M0.25228,938 shs23,705 shsSLDBSolid Biosciences$2.62-6.1%$3.68$2.45▼$10.46$205.77M2.321.02 million shs450,107 shsVIGLVigil Neuroscience$2.47-2.2%$1.94$1.31▼$6.06$115.05M1.9475,799 shs11,727 shsMetaverse Stocks And Why You Can't Ignore ThemThinking about investing in Meta, Roblox, or Unity? Enter your email to learn what streetwise investors need to know about the metaverse and public markets before making an investment.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceARCTArcturus Therapeutics+2.33%+5.52%+22.27%-25.22%-58.70%ORKAOruka Therapeutics-1.33%+3.55%+25.26%-18.96%+961,999,900.00%SLDBSolid Biosciences-3.79%-17.21%+3.33%-20.96%-71.38%VIGLVigil Neuroscience-0.40%+4.56%+69.13%-6.32%-30.96%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationARCTArcturus Therapeutics2.8611 of 5 stars4.60.00.00.02.62.50.6ORKAOruka Therapeutics3.2756 of 5 stars3.60.00.00.03.24.20.6SLDBSolid Biosciences3.9859 of 5 stars3.74.00.00.03.83.31.3VIGLVigil Neuroscience3.5212 of 5 stars3.64.00.00.02.82.51.3Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceARCTArcturus Therapeutics 3.13Buy$58.80423.36% UpsideORKAOruka Therapeutics 3.22Buy$39.86322.89% UpsideSLDBSolid Biosciences 3.33Buy$15.67497.96% UpsideVIGLVigil Neuroscience 3.20Buy$16.25559.23% UpsideCurrent Analyst Ratings BreakdownLatest VIGL, SLDB, ARCT, and ORKA Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails5/13/2025ARCTArcturus TherapeuticsCanaccord Genuity GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$68.00 ➝ $66.005/5/2025VIGLVigil NeuroscienceWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform$13.00 ➝ $13.004/24/2025VIGLVigil NeuroscienceWilliam BlairSubscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeStrong-Buy4/10/2025ARCTArcturus TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$60.00 ➝ $60.003/14/2025VIGLVigil NeuroscienceWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOutperform ➝ Outperform$24.00 ➝ $13.003/14/2025VIGLVigil NeuroscienceHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$17.00 ➝ $14.003/13/2025SLDBSolid BiosciencesJPMorgan Chase & Co.Subscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOverweight ➝ Overweight$12.00 ➝ $11.003/10/2025ARCTArcturus TherapeuticsBTIG ResearchSubscribe to MarketBeat All Access for the recommendation accuracy ratingSet Price TargetBuy ➝ Buy$48.003/10/2025ARCTArcturus TherapeuticsCanaccord Genuity GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$74.00 ➝ $68.003/10/2025SLDBSolid BiosciencesHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$16.00 ➝ $20.003/7/2025ARCTArcturus TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$63.00 ➝ $60.00(Data available from 5/14/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookARCTArcturus Therapeutics$138.39M2.20N/AN/A$10.42 per share1.08ORKAOruka TherapeuticsN/AN/AN/AN/AN/AN/ASLDBSolid Biosciences$8.09M25.10N/AN/A$6.27 per share0.42VIGLVigil NeuroscienceN/AN/AN/AN/A$3.24 per shareN/ACompare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateARCTArcturus Therapeutics-$29.73M-$3.01N/AN/AN/A-36.39%-22.39%-14.81%N/AORKAOruka Therapeutics-$5.34M-$5.79N/AN/AN/AN/A-24.96%-21.22%5/15/2025 (Estimated)SLDBSolid Biosciences-$96.01M-$3.04N/AN/AN/AN/A-58.75%-47.84%5/21/2025 (Estimated)VIGLVigil Neuroscience-$82.64M-$2.05N/AN/AN/AN/A-83.89%-65.34%N/ALatest VIGL, SLDB, ARCT, and ORKA EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/21/2025Q1 2025SLDBSolid Biosciences-$0.53N/AN/AN/AN/AN/A5/15/2025Q1 2025ORKAOruka Therapeutics-$0.57N/AN/AN/AN/AN/A5/12/2025Q1 2025ARCTArcturus Therapeutics-$1.58-$0.52+$1.06-$0.52$25.64 million$29.38 million5/7/2025Q1 2025VIGLVigil Neuroscience-$0.53-$0.49+$0.04-$0.49N/AN/A3/13/2025Q4 2024VIGLVigil Neuroscience-$0.49-$0.57-$0.08-$0.57N/AN/A3/6/2025Q4 2024ARCTArcturus Therapeutics-$0.33-$1.11-$0.78-$1.11$44.64 million$22.77 million3/6/2025Q4 2024ORKAOruka Therapeutics-$0.68-$0.49+$0.19-$0.49N/AN/ACompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthARCTArcturus Therapeutics$0.716.36%N/AN/A N/AORKAOruka TherapeuticsN/AN/AN/AN/AN/ASLDBSolid BiosciencesN/AN/AN/AN/AN/AVIGLVigil NeuroscienceN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioARCTArcturus TherapeuticsN/A4.764.76ORKAOruka TherapeuticsN/A22.8922.89SLDBSolid BiosciencesN/A7.857.85VIGLVigil NeuroscienceN/A3.723.72Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipARCTArcturus Therapeutics94.54%ORKAOruka Therapeutics56.44%SLDBSolid Biosciences81.46%VIGLVigil Neuroscience83.64%Insider OwnershipCompanyInsider OwnershipARCTArcturus Therapeutics16.60%ORKAOruka Therapeutics22.67%SLDBSolid Biosciences1.90%VIGLVigil Neuroscience18.01%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableARCTArcturus Therapeutics18027.12 million22.94 millionOptionableORKAOruka TherapeuticsN/A37.44 million27.07 millionN/ASLDBSolid Biosciences10077.50 million35.05 millionOptionableVIGLVigil Neuroscience4046.67 million27.38 millionNot OptionableVIGL, SLDB, ARCT, and ORKA HeadlinesRecent News About These CompaniesHC Wainwright Expects Higher Earnings for Vigil NeuroscienceMay 13 at 1:13 AM | marketbeat.comQ2 EPS Estimate for Vigil Neuroscience Increased by AnalystMay 13 at 1:13 AM | marketbeat.comHC Wainwright Issues Optimistic Forecast for VIGL EarningsMay 13 at 1:04 AM | americanbankingnews.comWedbush Lifts Earnings Estimates for Vigil NeuroscienceMay 13 at 1:04 AM | americanbankingnews.comVigil Neuroscience, Inc.: Vigil Neuroscience Reports First Quarter 2025 Financial Results and Provides Recent Business UpdatesMay 7, 2025 | finanznachrichten.deWedbush Reaffirms Outperform Rating for Vigil Neuroscience (NASDAQ:VIGL)May 7, 2025 | marketbeat.comVigil Neuroscience Reports First Quarter 2025 Financial Results and Provides Recent Business UpdatesMay 7, 2025 | globenewswire.comMarshall Wace LLP Acquires 122,853 Shares of Vigil Neuroscience, Inc. (NASDAQ:VIGL)May 6, 2025 | marketbeat.comVigil Neuroscience Inc.May 6, 2025 | barrons.comBoothbay Fund Management LLC Makes New $249,000 Investment in Vigil Neuroscience, Inc. (NASDAQ:VIGL)May 5, 2025 | marketbeat.comRenaissance Technologies LLC Has $624,000 Holdings in Vigil Neuroscience, Inc. (NASDAQ:VIGL)May 5, 2025 | marketbeat.com683 Capital Management LLC Purchases 180,420 Shares of Vigil Neuroscience, Inc. (NASDAQ:VIGL)May 4, 2025 | marketbeat.comVigil Neuroscience (VIGL) Projected to Post Earnings on TuesdayMay 1, 2025 | marketbeat.comWhy Vigil Neuroscience, Inc.’s (VIGL) Stock Is Up 5.73%April 30, 2025 | aaii.comVigil Neuroscience Stock Short Interest Report | NASDAQ:VIGL | BenzingaApril 30, 2025 | benzinga.comVigil Neuroscience (NASDAQ:VIGL) Upgraded by William Blair to "Strong-Buy" RatingApril 28, 2025 | marketbeat.comVigil presents data on oral small molecule program including VG-3927April 3, 2025 | markets.businessinsider.comWilliam Blair Remains a Buy on Vigil Neuroscience Inc (VIGL)April 3, 2025 | markets.businessinsider.comVigil Neuroscience Presents Data on its Small Molecule TREM2 Agonist VG-3927 in Two Oral Presentations at AD/PD™ 2025 International ConferenceApril 2, 2025 | globenewswire.comVigil Neuroscience Reports 2024 Results and Clinical ProgressApril 2, 2025 | tipranks.comVigil Neuroscience files to sell 5.38M shares of common stock for holdersApril 1, 2025 | markets.businessinsider.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeVIGL, SLDB, ARCT, and ORKA Company DescriptionsArcturus Therapeutics NASDAQ:ARCT$11.24 -0.63 (-5.27%) As of 10:53 AM Eastern This is a fair market value price provided by Polygon.io. Learn more.Arcturus Therapeutics Holdings Inc., a late-stage clinical messenger RNA medicines and vaccine company, focuses on the development of infectious disease vaccines and other products within liver and respiratory rare diseases. Its technology platforms include LUNAR lipid-mediated delivery and STARR mRNA. The company is developing ARCT-810 (LUNAR-OTC), a mRNA-based therapeutic candidate, which is in Phase 2 clinical trial for treating ornithine transcarbamylase deficiency; and ARCT-154 (LUNAR-COV19), a mRNA vaccine candidate that is in Phase 3 arm of a Phase 1/2/3 study in Vietnam for the treatment of COVID-19, as well as ARCT-032 (LUNAR-CF), a mRNA therapeutic candidate for cystic fibrosis. Its product pipeline includes, ARCT-2301 for bivalent: ancestral/omicron which is in Phase 3; ARCT-2303 for monovalent that is in Phase 3; ARCT-2138 for quadrivalent which is in Phase 1; and LUNAR-FLU which is in pre-clinical trial. Arcturus Therapeutics Holdings Inc. was founded in 2013 and is headquartered in San Diego, California.Oruka Therapeutics NASDAQ:ORKA$9.43 -0.20 (-2.03%) As of 10:53 AM Eastern This is a fair market value price provided by Polygon.io. Learn more.Oruka Therapeutics, Inc. is a biotechnology company, which focuses on developing novel monoclonal antibody therapeutics for PsO and other I&I indications. Its pipeline includes ORKA-001 and ORKA-002. The company is headquartered in Menlo Park, CA.Solid Biosciences NASDAQ:SLDB$2.62 -0.17 (-6.09%) As of 10:53 AM Eastern This is a fair market value price provided by Polygon.io. Learn more.Solid Biosciences Inc., a life science company, develops therapies for neuromuscular and cardiac diseases in the United States. The company's lead product candidate is SGT-003, a gene transfer candidate for the treatment of Duchenne muscular dystrophy; and SGT-501 to treat Catecholaminergic polymorphic ventricular tachycardia. It is also developing AVB-401 for the treatment of BAG3-mediated dilated cardiomyopathy; SGT-601 to treat a rare cardiac disease characterized by mutations in the gene that codes for cardiac troponin T protein, which helps coordinate contraction of the heart muscle; SGT-701 for treatment of rare inherited disease characterized by mutations in the RBM20 gene, a cardiac splicing factor that regulates alternative splicing, and codes for RNA binding motif protein 20; and AVB-202-TT to treat Friedreich's ataxia, as well as other drugs for the treatment of cardiac and other diseases. In addition, the company is involved in developing platform technologies, including capsid libraries and dual gene expression, a technology for packaging multiple transgenes into one capsid. The company has collaboration and license agreement with Ultragenyx Pharmaceutical Inc. to develop and commercialize new gene therapies for Duchenne; and a license agreement with the University of Washington, University of Missouri, and University of Florida. Solid Biosciences Inc. was incorporated in 2013 and is headquartered in Charlestown, Massachusetts.Vigil Neuroscience NASDAQ:VIGL$2.46 -0.06 (-2.18%) As of 10:53 AM Eastern This is a fair market value price provided by Polygon.io. Learn more.Vigil Neuroscience, Inc., a clinical-stage biotechnology company, focuses on developing treatments for rare and common neurodegenerative diseases by restoring the vigilance of microglia, the sentinel immune cells of the brain. Its lead candidate is VGL101(Iluzanebart), a human monoclonal antibody agonist targeting human triggering receptor expressed on myeloid cells 2 and is in a Phase 2 trial in patients with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), a rare and fatal neurodegenerative disease. The company is also developing VG-3927, an orally-available small molecule TREM2 agonist to treat common neurodegenerative diseases associated with microglial dysfunction, with an initial focus on Alzheimer's disease in genetically defined subpopulations, which is being evaluated in a Phase 1 clinical trial. It has license agreement with Amgen Inc. to commercially develop, manufacture, use, distribute, and sell therapeutic products containing compounds that bind to TREM2. The company was incorporated in 2020 and is headquartered in Watertown, Massachusetts. 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