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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:AUPHNASDAQ:EPZMNASDAQ:KRTXNASDAQ:PRNBNASDAQ:RARX On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAUPHAurinia Pharmaceuticals$7.57+1.0%$8.06$5.20▼$10.67$1.03B1.161.37 million shs1.01 million shsEPZMEpizyme$1.47$1.47$0.41▼$5.80$247.44M-0.413.23 million shs7,960 shsKRTXKaruna Therapeutics$329.83$327.01$158.38▼$329.99$12.58B1.18832,048 shs5 shsPRNBPrincipia Biopharma$100.05$100.05$25.35▼$101.89$3.32B0.86729,676 shsN/ARARXRa Pharmaceuticals$47.99$47.99$19.64▼$48.02$2.27B1.051.16 million shs30,200 shs13 Stocks Institutional Investors Won't Stop BuyingWhich stocks are hedge funds and endowments buying in today's market? Enter your email address and we'll send you MarketBeat's list of thirteen stocks that institutional investors are buying now.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAUPHAurinia Pharmaceuticals0.00%-12.43%-5.31%-3.12%+38.32%EPZMEpizyme0.00%0.00%0.00%0.00%0.00%KRTXKaruna Therapeutics0.00%0.00%0.00%0.00%0.00%PRNBPrincipia Biopharma0.00%0.00%0.00%0.00%0.00%RARXRa Pharmaceuticals0.00%0.00%0.00%0.00%0.00%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationAUPHAurinia Pharmaceuticals3.1101 of 5 stars3.51.00.00.02.50.82.5EPZMEpizymeN/AN/AN/AN/AN/AN/AN/AN/AKRTXKaruna TherapeuticsN/AN/AN/AN/AN/AN/AN/AN/APRNBPrincipia BiopharmaN/AN/AN/AN/AN/AN/AN/AN/ARARXRa PharmaceuticalsN/AN/AN/AN/AN/AN/AN/AN/ACompare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceAUPHAurinia Pharmaceuticals 3.00Buy$11.5052.00% UpsideEPZMEpizyme 0.00N/AN/AN/AKRTXKaruna Therapeutics 0.00N/AN/AN/APRNBPrincipia Biopharma 0.00N/AN/AN/ARARXRa Pharmaceuticals 0.00N/AN/AN/ACurrent Analyst Ratings BreakdownCompare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookAUPHAurinia Pharmaceuticals$235.13M4.35$0.31 per share24.61$2.68 per share2.82EPZMEpizyme$37.43M6.61N/AN/A($0.54) per share-2.72KRTXKaruna Therapeutics$654K19,239.07N/AN/A$33.24 per share9.92PRNBPrincipia Biopharma$35.16M94.50N/AN/A$10.95 per share9.14RARXRa Pharmaceuticals$3M757.11N/AN/A$5.56 per share8.63Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateAUPHAurinia Pharmaceuticals$5.75M$0.2827.0213.51N/A16.11%14.27%9.93%7/30/2025 (Estimated)EPZMEpizyme-$251.12M-$1.72N/AN/AN/A-391.90%-2,459.33%-69.74%N/AKRTXKaruna Therapeutics-$433.68M-$11.72N/AN/AN/AN/A-31.63%-30.38%N/APRNBPrincipia Biopharma-$53.79M-$2.09N/AN/AN/AN/A-23.08%-21.11%N/ARARXRa Pharmaceuticals-$102.69M-$2.31N/AN/AN/AN/A-44.61%-41.60%N/ALatest PRNB, KRTX, EPZM, AUPH, and RARX EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/12/2025Q1 2025AUPHAurinia Pharmaceuticals$0.08$0.16+$0.08$0.16$61.06 million$62.47 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthAUPHAurinia PharmaceuticalsN/AN/AN/AN/AN/AEPZMEpizymeN/AN/AN/AN/AN/AKRTXKaruna TherapeuticsN/AN/AN/AN/AN/APRNBPrincipia BiopharmaN/AN/AN/AN/AN/ARARXRa PharmaceuticalsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioAUPHAurinia Pharmaceuticals0.165.935.26EPZMEpizymeN/A5.355.19KRTXKaruna TherapeuticsN/A19.3119.31PRNBPrincipia BiopharmaN/A17.0117.01RARXRa Pharmaceuticals0.0114.7814.79Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipAUPHAurinia Pharmaceuticals36.83%EPZMEpizyme76.45%KRTXKaruna TherapeuticsN/APRNBPrincipia Biopharma95.54%RARXRa PharmaceuticalsN/AInsider OwnershipCompanyInsider OwnershipAUPHAurinia Pharmaceuticals12.20%EPZMEpizyme23.40%KRTXKaruna Therapeutics13.20%PRNBPrincipia Biopharma16.01%RARXRa Pharmaceuticals4.30%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableAUPHAurinia Pharmaceuticals300135.10 million118.62 millionOptionableEPZMEpizyme250168.33 million128.97 millionOptionableKRTXKaruna Therapeutics33938.15 million33.16 millionOptionablePRNBPrincipia Biopharma6533.21 millionN/ANot OptionableRARXRa Pharmaceuticals7247.33 millionN/AOptionablePRNB, KRTX, EPZM, AUPH, and RARX HeadlinesRecent News About These CompaniesAntibiotic Use Increases the Risk of Rheumatoid ArthritisOctober 13, 2024 | emjreviews.comETelix buys radiopharmacy network for $230M up front to expand US capacitySeptember 24, 2024 | endpts.comERheumatoid Arthritis and RA-ILD Linked to Increased Lung Cancer RiskSeptember 21, 2024 | rheumatologyadvisor.comRDeepCure links with Leeds Institute to bring AI-based RA drug to clinicAugust 20, 2024 | msn.comWhat Are the Treatment Options for Rheumatoid Arthritis?August 15, 2024 | healthline.comHTriple Therapy and TNF Inhibitor Treatments Differently Modify Lipid Profiles in RAAugust 9, 2024 | rheumatologyadvisor.comRRheumatoid Arthritis and RA-Associated Interstitial Lung Disease Linked to Higher Lung Cancer RiskAugust 9, 2024 | medscape.comMHigher Medication Adherence Linked to Reduced Adverse Outcomes in RAJuly 24, 2024 | rheumatologyadvisor.comRAbatacept Slows Atherosclerosis Progression Among High-Risk RA PatientsMay 28, 2024 | rheumatologyadvisor.comRDrug Insight: Tumor Necrosis Factor Converting Enzyme as a Pharmaceutical Target for Rheumatoid ArthritisFebruary 4, 2024 | medscape.comMRA: Discount Continues To Leave Some OpportunityJanuary 23, 2024 | seekingalpha.comFusion Pharma marks in-house radiopharma manufacturing success, details PhII/III trial studyJanuary 5, 2024 | endpts.comEAmon-Ra St. Brown pays off friendly wager he quips was made 'outside the facility'November 9, 2023 | freep.comFDetroit Lions game balls and goats: Amon-Ra St. Brown delivers; DBs need to be betterNovember 7, 2023 | freep.comFDetroit Lions No. 1 WR Amon-Ra St. Brown doubtful to play against Carolina PanthersOctober 27, 2023 | freep.comFImperial Petroleum, ARS Pharmaceuticals Stock, and More See Action From Activist InvestorsSeptember 8, 2023 | barrons.comAnthera Pharmaceuticals (ANTH) Stock Dropping After Pricing Public OfferingMay 29, 2023 | thestreet.comCourt rules for drugmakers in 340B fight over contract pharmaciesJanuary 31, 2023 | biopharmadive.comBUPDATE 1-AstraZeneca to buy U.S.-based CinCor Pharma in $1.8 bln dealJanuary 10, 2023 | msn.comAstraZeneca to buy CinCor Pharma in $1.8 billion dealJanuary 9, 2023 | poandpo.comPNew MarketBeat Followers Over TimeMedia Sentiment Over TimePRNB, KRTX, EPZM, AUPH, and RARX Company DescriptionsAurinia Pharmaceuticals NASDAQ:AUPH$7.57 +0.08 (+1.01%) Closing price 07/3/2025 03:58 PM EasternExtended Trading$7.56 0.00 (-0.01%) As of 07/3/2025 04:49 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Aurinia Pharmaceuticals Inc., a commercial-stage biopharmaceutical company, focuses on developing and commercializing therapies to treat various diseases with unmet medical need in the United States. It offers LUPKYNIS for the treatment of adult patients with active lupus nephritis. It has a collaboration and license agreement with Otsuka Pharmaceutical Co., Ltd. The company was incorporated in 1993 and is headquartered in Edmonton, Canada.Epizyme NASDAQ:EPZMEpizyme, Inc., a commercial-stage biopharmaceutical company, discovers, develops, and commercializes novel epigenetic medicines for patients with cancer and other diseases in the United States. The company offers Tazemetostat for the treatment of metastatic or locally advanced epithelioid sarcoma for adults and pediatric patients. It also develops R-CHOP in front-line patients with high risk diffuse large B-cell lymphoma; and PARP inhibitor in patients with PARPi-resistant solid tumors, such as castration-resistant prostate cancer, small cell lung cancer, and others. In addition, the company develops Tazemetostat in patients with INI1-negative tumors in adults and pediatrics; PRMT5 inhibitor for patients with solid tumors; and PRMT1 inhibitor. It has collaboration agreements with Roche Molecular Systems, Inc.; Lymphoma Academic Research Organization; Eisai Co. Ltd.; HUTCHMED (China) Limited; and Roche Sequencing Solutions, Inc. The company was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.Karuna Therapeutics NASDAQ:KRTXKaruna Therapeutics, Inc., a clinical-stage biopharmaceutical company, creates and delivers transformative medicines for people living with psychiatric and neurological conditions. Its lead product candidate includes KarXT, an oral modulator of muscarinic receptors for the treatment of acute psychosis in patients with schizophrenia; and for the treatment of central nervous system disorders, such as negative and cognitive symptoms of schizophrenia and psychosis, as well as for the treatment of various peripheral tissues and dementia-related psychosis, including Alzheimer's disease. The company also focuses on developing other muscarinic-targeted drug candidates; and intends to develop lead candidature TRPC4/5 and KAR-2618 for the treatment of depressive disorder. Karuna Therapeutics, Inc. has a license agreement with Eli Lilly and Company, and Zai Lab (Shanghai) Co., Ltd; patent license agreement with PureTech Health LLC; and drug discovery partnership with Charles River Laboratories, as well as drug discovery collaboration with PsychoGenics, Inc. The company was formerly known as Karuna Pharmaceuticals, Inc. and changed its name to Karuna Therapeutics, Inc. in March 2019. Karuna Therapeutics, Inc. was incorporated in 2009 and is headquartered in Boston, Massachusetts.Principia Biopharma NASDAQ:PRNBPrincipia Biopharma Inc., a late-stage biopharmaceutical company, focuses on developing novel therapies for immunology and oncology. The company is developing PRN1008, an inhibitor that is in Phase III clinical trial for the treatment of pemphigus, a chronic skin disease, as well as in Phase II clinical trial to treat immune thrombocytopenic purpura. It is also developing PRN2246/SAR442168, an inhibitor, which has completed Phase I clinical trial for treating multiple sclerosis (MS) and other central nervous system (CNS) diseases; PRN1371, a drug candidate that is in Phase I clinical trial for the treatment of solid tumors; and oral small molecule inhibitors of the immunoproteasome. The company has a collaboration agreement with Genzyme Corporation to develop relapsing and progressive MS and other diseases of the CNS. Principia Biopharma Inc. was incorporated in 2008 and is headquartered in South San Francisco, California.Ra Pharmaceuticals NASDAQ:RARXRa Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops therapeutics for the treatment of diseases caused by excessive or uncontrolled activation of the complement system. The company's peptide chemistry platform enables the production of synthetic macrocyclic peptides that combine the diversity and specificity of antibodies with the pharmacological properties of small molecules. Its lead product candidate is Zilucoplan, an injection into the tissue under the skin that has completed Phase II clinical trial for the treatment of generalized myasthenia gravis (gMG); has completed Phase II clinical trial for treating paroxysmal nocturnal hemoglobinuria (PNH); and has completed Phase Ib clinical trial to treat patients with renal impairment. The company's pre-clinical programs include Factor D inhibition for treating C3 glomerulonephritis and dense deposit disease; and inhibitors of other complement factors for renal, autoimmune, and central nervous system diseases. It has collaboration and license agreement with Merck & Co., Inc. to identify orally available cyclic peptides for non-complement program targets, and provide research and development services. Ra Pharmaceuticals, Inc. was founded in 2008 and is headquartered in Cambridge, Massachusetts. 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