Illumina Q3 2023 Earnings Report

Illumina EPS Results

• Actual EPS: $0.33
• Consensus EPS: $0.13
• Beat/Miss: Beat by +$0.20
• One Year Ago EPS: $0.34

Illumina Revenue Results

• Actual Revenue: $1.12 billion
• Expected Revenue: $1.13 billion
• Beat/Miss: Missed by -$13.70 million
• YoY Revenue Growth: +0.40%

Illumina Announcement Details

• Quarter: Q3 2023
• Date: 11/9/2023
• Time: After Market Closes
• Conference Call Date: Thursday, November 9, 2023
• Conference Call Time: 5:00PM ET

Illumina (NASDAQ:ILMN) develops and manufactures genomic analysis technologies used by researchers, healthcare providers, pharmaceutical companies and other organizations. Its offerings include next-generation DNA sequencing systems, microarray platforms, consumables, laboratory services and bioinformatics software designed to help analyze genetic variation and biological functions.

The company’s sequencing instruments include systems for a range of applications and throughput levels, such as the NovaSeq, NextSeq, MiSeq and iSeq platforms. Illumina also provides software and informatics solutions, including DRAGEN, as well as workflow products and services supporting applications in oncology, reproductive health, genetic disease research, population genomics, infectious disease and drug development.

Founded in 1998 and headquartered in San Diego, California, Illumina serves customers in North America, Europe, Asia-Pacific and other international markets through direct operations, distributors and commercial partners. Jacob Thays has served as the company’s president and chief executive officer since 2023. Illumina completed the divestiture of its former cancer-detection subsidiary, GRAIL, in 2024.

Illumina Q3 2023 Earnings Call Transcript

Key Takeaways

• Q3 2023 revenues were flat at $1.12 billion and non-GAAP EPS of $0.33, reflecting continuing macroeconomic headwinds.
• 2023 guidance revised: full-year revenue now expected to decline 2%–3% with non-GAAP EPS of $0.60–0.70; NovaSeq X placement forecast cut to 330–340 units.
• NovaSeq X momentum continues with 310 orders since launch, 97 shipments in Q3 (installed base 273) and early data showing 29% YoY growth in sequencing output.
• Operational discipline delivered run-rate expense reductions of $175 million, exceeding the initial $100 million goal and bolstering non-GAAP margins.
• Board established a special committee to accelerate the GRAIL divestiture process under EU transitional measures, exploring sale, spin-off or capital-markets options.

Presentation

[Operator]

Good day, ladies and gentlemen, and welcome to the Q3 2023 Illumina Earnings Conference Call. At this time, all participants are in a listen-only mode. After the speaker's presentation, there will be a question-and-answer session. Please be advised that today's conference is being recorded. I would now like to hand the conference over to Salli Schwartz, Vice President of Investor Relations.

[Salli Schwartz, VP of Investor Relations at Illumina]

Hello, everyone, and welcome to our earnings call for the Q3 of 2023. During the call today, we will review the financial results we released after the close of the market and offer commentary on our commercial and regulatory activity, after which we will host a question-and-answer session. Our earnings release can be found in the Investor Relations section of our website at illumina.com. Participating for Illumina today will be Jacob Thaysen, Chief Executive Officer, and Joydeep Goswami, Chief Financial Officer and Chief Strategy and Corporate Development Officer. Jacob will provide an update on the state of Illumina's business, and Joydeep will review our financial results, which include GRAIL. As a reminder, GRAIL must be held and operated separately and independently from Illumina, pursuant to the transitional measures ordered by the European Commission, which prohibited our acquisition of GRAIL under the EU Merger Regulation.

[Salli Schwartz, VP of Investor Relations at Illumina]

This call is being recorded, and the audio portion will be archived in the investor section of our website. It is our intent that all forward-looking statements regarding our financial results and commercial activity made during today's call will be protected under the Private Securities Litigation Reform Act of 1995. Forward-looking statements are subject to risks and uncertainties. Actual events or results may differ materially from those projected or discussed. All forward-looking statements are based upon current available information, and Illumina assumes no obligation to update these statements. To better understand the risks and uncertainties that could cause actual results to differ, we refer you to the documents that Illumina files with the Securities and Exchange Commission, including Illumina's most recent Forms 10-Q and 10-K. With that, I'll now turn the call over to Jacob.

[Jacob Thaysen, CEO at Illumina]

Thank you, Salli. Good day, everyone, and thank you for joining today's call. As you know, I assumed the role as Illumina's CEO a little over six weeks ago. It is an honor to lead this company. I joined Illumina after more than a decade at Agilent, where I ran both the Diagnostic and Genomics Group and more recently, Agilent's largest business, the Life Sciences and Applied Markets Group. I have long admired Illumina for its role in building the genomics market, and I'm incredibly excited to be here. During my first weeks, I prioritized getting to know our employees and meeting with several of our customers. Illumina has a highly capable team, and I have been impressed with their level of passion and commitment to our work. Both our employees and our customers are driven to move genomics forward.

[Jacob Thaysen, CEO at Illumina]

Like our team, I'm passionate about genomics and the role that this field can play in healthcare and personalized medicine, particularly in the oncology space. This is a massive opportunity, and Illumina will remain the key player even as others enter the market. Illumina's infrastructure that we have built over two and a half decades, our compelling offerings that sets the global standard, and our deep commitment to innovation for the future will continue to drive the use of genomics and multi-omics around the world. Turning to our Q3 results. In Q3, Illumina delivered revenue of approximately $1.12 billion, flat year-over-year, or up 1% on a constant currency basis. This was a disappointing result. The macroeconomic environment remains challenging for our industry and for our customers, with customers increasingly cautious and constrained in their purchasing decisions.

[Jacob Thaysen, CEO at Illumina]

Despite a lower growth margin year over year, tight management of our operating expenses allowed us to deliver diluted Non-GAAP EPS of $0.33, also approximately flat year over year. While we cannot control external environment, Illumina's management team and I remain focused on supporting our customers and our own operational execution. Part of my comprehensive review of the business includes reexamining our strategic initiatives and our targets for long-term revenue growth and operating margins. We will lay out our new targets for you later next year. A key priority for me is to get clarity on the GRAIL situation. Therefore, I have requested and the board has established a special committee to expedite decisions on GRAIL. Furthermore, we have retained advisors and are preparing for sale and capital markets transactions. We expect to file a Form 10 on a confidential basis with the SEC.

[Jacob Thaysen, CEO at Illumina]

Hereafter, we will contact third parties as investment capital sources or as potential purchasers as our appeals are ongoing. I know there have been questions regarding our appeals. These appeals are not just about GRAIL. They provide Illumina with flexibility for any divestiture of GRAIL and also for future transactions. The appeals will not impact our ability to move swiftly. Make no mistake, I'm here to focus on the core business, which I will talk more about after Joydeep's remarks. Joydeep?

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Thank you, Jacob. I'll start by reviewing our consolidated financial results, followed by segment results for Core Illumina and GRAIL, and then conclude with my remarks on our current outlook for 2023. I will be discussing Non-GAAP results, which include stock-based compensation.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

... I encourage you to review the GAAP reconciliation of these non-GAAP measures, which can be found in today's release and in the supplementary data available on our website. As Jacob noted, in the Q3, consolidated revenue of $1.12 billion was flat year over year and up 1% on a constant currency basis. Consolidated revenue was down 5% from the Q2 of 2023. Although we correctly anticipated a sequential decrease in high-throughput consumables revenue due to the NovaSeq X transition, we placed fewer NovaSeq X instruments than we expected in the quarter as customers' purchase constraints led to lengthened sales cycles. Non-GAAP net income was $52 million, or $0.33 per diluted share, which included dilution from GRAIL's non-GAAP operating loss of $155 million for the quarter.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Despite our lower revenue, non-GAAP EPS exceeded our expectations, primarily due to continued execution of expense reduction in initiatives and a higher gross margin than we forecast. GAAP net loss was $754 million, or $4.77 per diluted share, which included goodwill and intangible impairments of $821 million related to the GRAIL segment. These impairments were primarily the result of a decrease in Illumina's consolidated market capitalization and a higher discount rate used for the fair value calculation of the GRAIL segment. Our non-GAAP tax rate was 39.7% for the quarter, which decreased from 43.2% in Q3 2022, with both quarters reflecting the impact of R&D capitalization requirements.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

The year-over-year decrease was primarily due to a decrease in the non-GAAP tax expense impact of R&D capitalization requirements, given increased amortization of capitalized R&D expenses. Our non-GAAP weighted average diluted share count for the quarter was approximately 158 million. Moving to segment results. Core Illumina revenue of $1.11 billion was flat year-over-year on both a reported and constant currency basis and included anticipated reductions of approximately 7 percentage points from two primary categories. One, the decrease in COVID surveillance and the effect of sanctions in Russia that together represent approximately 3.5 percentage points. And two, the year-over-year reduction in China revenue, that also is approximately 3.5 percentage points. COVID surveillance contributed approximately $4 million in total revenue in Q3 2023, compared to $28 million in Q3 2022.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Core Illumina sequencing consumables revenue of $695 million was down 4% year over year. The decrease was primarily driven by a 12% decline in sales to research customers. These customers were impacted by the NovaSeq X transition and are reducing NovaSeq 6000 consumables purchases before they have fully ramped up activity on NovaSeq X. Total sequencing consumables revenue was also impacted by the COVID, Russia, and China factor, as I noted previously, as well as the impact of macroeconomic conditions on customers' purchasing power and project planning. Strengthen sales to clinical customers partially offset the decline in research, with clinical sequencing consumables growing 10% year over year, led by continued momentum in oncology and genetic disease testing.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Turning to sequencing activity, total sequencing gigabase output on our connected high and mid-throughput instruments grew 5% from Q2 2023 and 29% year-over-year. We are encouraged by the trends we are seeing across both research and clinical high-throughput customers that have a NovaSeq X installed. As expected, these customers show higher overall growth in sequencing output than high-throughput customers that have not yet adopted the NovaSeq X, both on a quarter-over-quarter and a year-over-year basis. As a reminder, we believe this data is a useful reference that shows the general activity trends across our installed base and is directionally correlated with revenue over time. Sequencing instruments revenue for Core Illumina of $179 million grew 10% year-over-year, driven primarily by NovaSeq X, which more than offset the decline in NovaSeq 6000 shipments.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Growth in high-throughput instruments was partially offset by the expected decline in mid-throughput due to increasing capital purchase and cash flow constraints that continue to impact our customers' purchasing behaviors globally, as well as by local competition in China. For NovaSeq X, we exited Q3 with more than 310 orders since launch. Our shipments of 97 NovaSeq X instruments in Q3 brought our total installed base to 273 instruments. Core Illumina sequencing service and other revenue of $142 million was up 15% year-over-year, driven primarily by higher instrument service contract revenue on a growing installed base, as well as an increase in lab services revenue. Moving to regional results for Core Illumina. All regions continued to be impacted by two key issues. One, tighter funding and budget pressures that are impacting customer purchasing power and project planning.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

The impact of high-throughput customers transitioning to NovaSeq X as customers continue to reduce NovaSeq 6000 consumables purchases before they have fully ramped up activity on NovaSeq X. Americas revenue of $650 million grew 10% year-over-year, attributed to NovaSeq X placements, as well as clinical testing volume, driving greater consumables revenue. Clinical sequencing consumable shipments grew more than 20% year-over-year. Europe revenue of $260 million was flat year-over-year, or up 1% on a constant currency basis. Growth in sequencing consumables was driven by mid-teens growth in clinical and strength in mid-throughput consumables, offset by the decline in COVID surveillance and the negative impact of exchange rates. For sequencing instruments, growth in high throughput due to NovaSeq X placements was more than offset by a decline in mid-throughput instruments.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

EMEA revenue of $98 million declined 22% year-over-year, or 19% on a constant currency basis, which included an 11 percentage point impact from sanctions in Russia. The year-over-year decrease was also driven by softness in Japan due to the macroeconomic factors I mentioned earlier, as well as the expected slowdown in COVID surveillance. Greater China revenue of $98 million represented a 26% decrease year-over-year, or 25% on a constant currency basis, reflecting continued macroeconomic and geopolitical challenges as well as local competition in mid throughput. Moving to the rest of Core Illumina P&L.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Core Illumina non-GAAP gross margin of 66% decreased 290 basis points year-over-year, primarily driven by product mix and less fixed cost leverage on lower manufacturing volumes, as well as lower instrument margins and higher field service and installation costs due to the NovaSeq X launch, which is typical in a launch year. Core Illumina non-GAAP operating expenses of $481 million were down $33 million year-over-year and were lower than expected, primarily due to continued expense reduction initiatives. As a result of these factors, Core Illumina non-GAAP operating margin was 22.5% in Q3 2023, compared to 22.6% in Q3 2022. Despite our lower gross margin, operating margin was approximately flat year-over-year due to our proactive cost management initiatives. Transitioning to financial results for GRAIL.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

GRAIL revenue of $21 million for the quarter grew 110% year-over-year, driven primarily by adoption of Galleri. GRAIL non-GAAP operating expenses totaled $161 million and increased $12 million year-over-year, driven primarily by efforts to scale GRAIL's commercial and R&D organizations. Moving to consolidated cash flow and balance sheet items. Cash flow provided by operations was $139 million. Q3 2023 capital expenditures were $45 million, and free cash flow was $94 million. We did not repurchase any common stock in the quarter. We ended the quarter with approximately $933 million in cash, cash equivalents, and short-term investments.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

During the Q3 of 2023, the company used $750 million in cash to repay the outstanding principal of convertible notes that matured in August 2023. Moving now to 2023 guidance. We now expect full-year 2023 consolidated revenue to decline 2%-3% from 2022, including Core Illumina revenue that is down 3%-4% year-over-year. As a reminder, these ranges include anticipated reductions from COVID surveillance of approximately 200 basis points, the impact on our business from sanctions in Russia of approximately 100 basis points, reductions in our business in China, as well as a year-over-year negative impact from foreign exchange rates. GRAIL revenue is now expected to be at the low end of the range of $90 million-$110 million for 2023.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

For fiscal 2023, we now expect Core Illumina sequencing instrument revenue to decline 5%-6% year-over-year, driven by capital and cash flow constraints that have continued to impact our customers' purchasing behaviors globally, as well as the decline in our business in China. The decrease from our prior guidance is primarily driven by our lower NovaSeq X shipment expectations for 2023. We now expect to ship between 330-340 NovaSeq X instruments for the year as customers' purchasing constraints lead to lengthened sales cycles.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

We also now expect Core Illumina sequencing consumables revenue to decline 5%-6% year-over-year, driven primarily by the decrease in NovaSeq 6000 consumables as customers transition to NovaSeq X, the impact of macroeconomic conditions on customer project planning and budgets, the effect of sanctions in Russia, the slowdown in COVID surveillance, and the decline in our business in China. The decrease from our prior guidance primarily reflects a slower ramp in NovaSeq X consumables, in part due to our lower placement expectations, as well as the increasing impacts of macroeconomic constraints. We now expect Core Illumina total sequencing revenue to decline 3%-4% year-over-year. This continues to include intercompany sales to GRAIL of approximately $30 million, which are eliminated in consolidation.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

We now expect consolidated Non-GAAP operating margin of 4%-4.5%, and Core Illumina Non-GAAP operating margin of 19%-19.5%. Our revised operating margins reflect our lower revenue expectations for the year, partially offset by continued expense reduction initiatives. We now expect our Non-GAAP tax rate to be approximately 39% for 2023, due to discrete tax benefit recognized in Q3 2023, related to prior year return adjustments. Lastly, we now expect Non-GAAP earnings per diluted share in the range of $0.60-$0.70 for 2023, reflecting Non-GAAP diluted shares outstanding of approximately 159 million shares. Dilution from GRAIL's Non-GAAP operating loss is now expected to be approximately $660 million, as GRAIL continues to manage its expense base in line of its latest revenue outlook.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

I will now turn it back over to Jacob for his closing remarks. Thank you.

[Jacob Thaysen, CEO at Illumina]

Before we go to Q&A, I wanted to reiterate Illumina's commitment to supporting our customers in this difficult macroeconomic environment. While we cannot control for external factors, we can optimize our own actions to successfully navigate through this period and position the company for a return to accelerated growth on the other side. I know you're interested to hear our views for 2024. With the caveat that we haven't finished 2023, we're still looking at our budget for 2024. Our initial views is that 2024 results will look very similar to 2023. We don't expect near-term improvement to the macroeconomic environment, and geopolitical issues have been persistent. We are encouraged with the early signs we're seeing for NovaSeq X utilization and the continued rollout of the X position us very well for the ramp in consumables and overall growth when the market conditions improve.

[Jacob Thaysen, CEO at Illumina]

This is clearly a dynamic situation, and we want to be able to develop our views in depth. Therefore, for 2024, we will not provide guidance before our Q4 earnings call in February. The main reason that I joined Illumina was my strong conviction about the future of the Core Illumina business. While over the coming months, I'll continue to listen and learn, I will also be focused on several key priorities. First, we need to drive our top line as much as possible in this environment. This means continuous placement of the NovaSeq X and all of our instruments, laying the groundwork for increased consumables demand. We'll continue working closely with our customers around the world, whether they are integrating new instruments into their workflows, starting new projects, or building new tests or assays.

[Jacob Thaysen, CEO at Illumina]

Second, we need to keep driving innovation that is highly focused on our customers' priorities. These innovations include automation and sample-to-answer solutions, serve to strengthen our leadership position around the world. At the same time, we need to manage our R&D investments with discipline and rigor. We most recently launched our 25B reagent kit. This was highly anticipated by our customers, and it will unleash the full power of the NovaSeq X. Third, we need to focus on our operational excellence across geographies, functions, and processes. Earlier this year, we announced a plan to reduce our annualized run rate expenses. Our team has executed well and has been able to reduce annualized run rate expenses by approximately $175 million, ahead of our original projection of more than $100 million.

[Jacob Thaysen, CEO at Illumina]

These savings will continue to support flexibility in further investment in high growth areas and our margins. I'm committed to executing against all of these priorities with a strong sense of urgency. We are focused on delivering tangible improvements that support profitable long-term growth for Illumina and for our shareholders. I will now invite the operator to open to the line of Q&A.

[Operator]

Thank you. If you would like to signal with questions, please press star one on your touch tone telephone. If you're joining us today using a speakerphone, please make sure your mute function is turned off to allow your signal to reach our equipment. As a reminder, please limit yourself to one question so that we can accommodate as many analysts as possible. You are welcome to reenter the queue if you have additional questions. Again, that is star one if you would like to signal with questions. Our first question comes from Vijay Kumar with Evercore ISI.

[Vijay Kumar, Senior Managing Director in Healthcare Services and Technology Research at Evercore ISI]

Hey, guys. Thanks for taking my question, and Jacob, welcome to Illumina. My maybe one question is on GRAIL, maybe a two-parter here. I think the EC gave us the order asking for 2.5 years of cash outflow. What does that mean, given GRAIL's current OpEx spending, is that $1.75 billion of cash outflow? And I think relates with that, I saw you announced a special committee. Who is on the special committee? What is the focus for this committee? Is there any more details? And it sounded something different than... Just want to understand what is different, what has changed?

[Jacob Thaysen, CEO at Illumina]

Yeah, Vijay, thank you very much, and I'm really excited to be here at Illumina. And let me start with your second question, and then I'll have Joydeep step in and also talking about what those two and a half years means. But as I discussed here, coming into the company, I felt it was very important to get clarity on GRAIL. And it was very important for me to have the support for the board and to make swift decisions to move forward. And thereby, we started a special committee with three of the board members, including, and then besides me, that is the chairing of that committee.

[Jacob Thaysen, CEO at Illumina]

So I have three board members, and plus me, that will work with the management team to really walk through all the elements around the divestiture order to make sure we can make some fast decisions. We need to make decisions which path we're gonna follow. Is it gonna be a trade sale, the spin, the split, with without a sponsor? And of course, there's a lot of considerations related to that. That's really what the special committee is helping me and the rest of the management team to do. Joydeep?

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Yeah, Vijay, hey, so on the, you know, on the two and a half years of cash support or to GRAIL, we're still working with the European Commission on, you know, exactly what that means in terms of a numerical number. So I'm not at liberty to disclose those details. We will come back with that when once we have alignment. But I think as Jacob alluded to, right, this is not something that we have to provide all on our own, right? We have several options now that, you know, we have worked with the EC to come up with a, or to have a divestiture order that is in line with our expectations of flexibility.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

To use, even in the case of a spin or a split decision, we can get in a sponsor that can support all or a part of the requirement for the 2.5 years of cash support, or we can go to the markets and raise that money as well. Right, so, stay tuned on that one.

[Operator]

Our next question will come from Dan Brennan with TD Cowen.

[Dan Brennan, Managing Director in Life Science and Diagnostic Tools Research at TD Cowen]

Hey, thanks, thanks for taking the questions here, Jacob. Welcome. Maybe just, I'll ask one, obviously, that's all we have, but maybe a two-parter. So maybe, Jacob, obviously, you left a great job at Agilent before coming here, and certainly we'll be interested to get your view on the growth rate and outlook for Illumina when you're ready to give that. But I'd be interested to get your view on kind of the overall NGS market and taking the job, like, thoughts on what type of growth characteristics you think, you know, are reasonable in that market. 'Cause given, you know, the price cuts, there's just a lot of question on demand elasticity. So I guess first one is on the NGS overall market, your view there. And then, B, I just had a question on the X specifically.

[Dan Brennan, Managing Director in Life Science and Diagnostic Tools Research at TD Cowen]

You know, I understand, you know, obviously, you're lowering the placement number given customer constraints, but can you give any color on the orders or the backlog that you have as of right now? And then the final part would just be on guidance. You know, Illumina's had, you know, a series of kind of guidance reductions. A lot of peers are facing the same issues, but you guys have had a, you know, more elongated period of this. So I'm just wondering kind of what changes can be made in order to hopefully, you know, better set guidance so that, you know, the, you know, the risk of these reductions is eliminated going forward. Thanks.

[Jacob Thaysen, CEO at Illumina]

No, thanks, Dan, and I think I would have Joydeep also jumping in on some of those elements here. But let me just start by coming here into Illumina and my observation, both from when I was outside Illumina but also coming in. I think that the core business has a tremendous opportunity. I think there's a lot of opportunities in the NGS markets, and I think we are definitely through a tough period right now. I think the whole life science tools industry is seeing it, and certainly here at Illumina, we're not immune for that. But the growth rates, even though I will spend time here over the next period of time still learning the business and really understand the organization.

[Jacob Thaysen, CEO at Illumina]

So at this point of time, I don't have a final opinion about what I think is the right growth rate for the business and what we're committing to. But I will certainly come back later in 2024 and share all of that with you when I'm ready for it. But in the meantime, I think that the overall market is very healthy, and there will be a lot of growth opportunities for Illumina going forward. And I can then say that. My, some of the findings coming into the company and really digging deep into our innovation engine and what our roadmaps look like, I'm very excited for the future of this company. I think we will continue to pioneer in this area.

[Jacob Thaysen, CEO at Illumina]

So, I think on guidance, and Joydeep, join in here also, but you know, in the end, we wanted to make sure we, when we signal also from especially 2024 here, that at this point, we wanna be prudent in how we set our... It's not a guidance yet, but at least how we view 2024, as we simply don't see any change, short-term changes in the economic environment, and therefore, we felt it was important to go out now and share our observations. But Joydeep, do you wanna-

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

No, I think, I think, Jacob, that's right. You know, on the guidance piece, look, we, we made a commitment to you to, you know, to come back to you with any read on the macroeconomics we see, and, and I think we've held up to that commitment. In fact, you know, we may have been a little bit, a canary in the coal mine, signaling some of this earlier to you, especially this year, than, than others, right? One of the things, of course, you did bring up was the elongated, you know, sort of lack of growth or the reduced growth that we have had. That is true.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

I think, you know, part of what hit us at the same time as the macroeconomics going down is the transition, major transition on our platform, which has hit us as customers move from the 6,000 to the X. But there's a gap between when they run down some of their inventory on the X and then, you know, wait to fully ramp up on Y.... on the X. So you will see that, you know, balance out over time. We don't have any doubts on that. And then, you know, on the X, I want to reemphasize, and I think you will have seen this from your channel checks as well, demand and interest in the innovation and the capabilities that the X brings remains strong.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

I think we are very excited about the launch of the 25B, and I think those of you who attended ASHG would have seen our customers' interest in that and the data that's coming out of the 25B, and the improvements that we continue to make on the software really resonate with our customers. So we remain very interested in that.

[Operator]

Our next question will come from Puneet Souda with Leerink Partners.

[Puneet Souda, Senior Managing Director of Life Science Tools and Diagnostics at Leerink Partners]

Yeah. Hi, Jacob. Good to have you on board here. So, if I could ask sort of two-part question. Just, you know, with the 25B launch, can you talk a little bit about how, and maybe Joydeep can chime in and talk about how the, you know, the transformation is going to be sort of over the next couple of months. You obviously get a price uptick with the 25B, but not all customers are going to be able to, you know, essentially fill up that flow cell. So there is going to be a bit of an ebb and flow. So maybe if you could talk a little bit about that, at least qualitatively in the near term. And then a bigger competition question.

[Puneet Souda, Senior Managing Director of Life Science Tools and Diagnostics at Leerink Partners]

Jacob, you've seen the LC-MS businesses and other businesses in China. You know, what do you imagine for China for Illumina with, you know, one of the bigger competitors over there? How do you see Illumina's position in China, you know, longer term? And if I may just ask on, you know, again, on competition, one of your, one of your diagnostic customers, NIPT and MRD customer, pointed out that they're validating different platforms. So, again, what's your view on competition? Thank you.

[Jacob Thaysen, CEO at Illumina]

No, thank you very much, Puneet, and again, I'm very pleased to be here. Let me start with the China question. As you're right, I have certainly some experience of running businesses in China, very familiar with the Chinese, the China itself and how to operate businesses there. So what is, of course, more unique for Illumina than some of our, some of the other life science tools companies, is that Illumina has a Chinese competitor that have at least good enough sequencing capabilities here. But China continues to be an extremely important country for us, and we are right now working through and in China for China strategy to really be much better positioned in China going forward.

[Jacob Thaysen, CEO at Illumina]

We are committing to China, and I think we can actually do really well in China. Many of our customers in China prefer us to work with Illumina for what we stand for, both quality, but also that we are the number one brand out there. So we will continue to be very strong in China. Generally speaking, on competition, yes, you're right. I mean, there are competition out there. As you also know, I'm very familiar with being in a very competitive environment. And I think that with what Illumina has, which I think will serve us extremely well, is that we have a very strong brand. We have a very strong install base. Almost all papers coming out is based on our technology.

[Jacob Thaysen, CEO at Illumina]

And also, of course, what I see internally with the roadmap we have for the pipeline of new products coming out, our innovation capabilities will continue to position us very extremely competitive in this environment. But of course, I understand, and I'm fully aware that we will be in a very competitive situation forward. In the end, I think that just keeps us really focused on our customers, and we'll do our best for our customers. So I'm here, I'm ready to fight for it.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Yeah, maybe I'll tag on there. Let me start with the competition. We, we obviously, as Jacob said, take it seriously, but also monitor it very, very carefully across the globe through what we're seeing out in the field. So I will say outside of China, we have seen the competition and share have been what we had expected, right? Obviously, with new market entrants, you will see a little bit of a decline in share, but you know, it has been outside of China, very much according to expectations.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

On the 25B, Puneet, you know, so let me start by saying, what we have seen in this is early indicators that, when we look at sequencing activity growth, and we measured it by gigabase, we are seeing that customers who have adopted the X have seen a faster growth rate in output, in sequencing output than customers who have not adopted the X, right? So this is an encouraging sign that X is actually spurring more sequencing activity, at these customers. And again, it's still very early days. They're ramping up. They're, you know, they're validating fully on their particular workflows. With 25B, I think you're right. It'll, you know, it will spur even more capacity and experiments.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

We've heard customers that want to run very large single cell experiments, for example, be very excited about this 25B and the capabilities that it brings. So we expect that to play out. I think when you get into the dynamics of whether you're running full flow cells or not, there is a very complex interaction of things that will lead to higher prices per gigabase until you fully load your flow cells. So we can get into that offline, but we do expect those dynamics to be very similar to what you saw when you brought on NovaSeq 6000 and then some of the other S4 flow cells, et cetera.

[Jacob Thaysen, CEO at Illumina]

... But I think also, Joydeep, on just to finish up on the opportunity areas that we have seen, at least the customers that I've met here, also in the clinical space, are very excited with the new flow cell as this opens up for new assays, new products, offering that they haven't had before. So while it will take them a little while, of course, to validate and get up and running, we see many of them right now are rushing to be first to market with this.

[Operator]

Our next question will come from Dan Arias with Stifel.

[Dan Arias, Managing Director of Life Sciences and Diagnostics Research at Stifel]

Yeah, hi, guys. Thanks for the question here. Jacob, just to follow up on the special committee that will look at GRAIL. What's the general timeline that they're expected to be on with respect to reaching a decision? And then can you update us on when the GRAIL team is expecting to see a readout for the NHS Galleri study at this point? Thanks.

[Jacob Thaysen, CEO at Illumina]

Yeah. So, I can tell you that we are working as quickly as we can under the framework to look at the options here. And I can tell you, I'm as frustrated as all of you, and I look forward to get this behind us. So we are looking on very-- working on very tight timelines. At this point, I don't want to commit to anything because I want to make sure that I can deliver on my commitments on any timeline here. So, by the way, I also want to share with you that this morning we got feedback from the ECJ, that they have now put in a date for the hearing, oral hearing, which will be mid December. So it's good news in the way that things now are moving forward.

[Jacob Thaysen, CEO at Illumina]

Just on that, the appeals are important to us, obviously for the reason of GRAIL, but probably as important for ensuring that we have the flexibility for future transactions that we will look into. So, and obviously also we can get rid of the fine and so on. So that's why the appeals continue to be important.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

NHS GRAIL readout timing, I think, you know, that's as GRAIL had stated before, that's the final expectation on that is some point in 2024, and they will have a early readout as well, or a preliminary readout before that.

[Operator]

We have a question from Michael Ryskin with Bank of America.

[Mike Ryskin, Managing Director of Life Science Tools and Diagnostics Research at Bank of America]

Great. Thanks for taking the question, and welcome aboard. I guess I want to follow up on the earlier question about sort of underlying demand in the market and what gives you confidence in some of the longer-term view. And I guess I'll phrase it in terms of your update to the guide here in the Q3. I mean, you're citing some of the same macro headwinds that others are in terms of what's going on in China, in terms of broader funding concerns and budget tightness. And you're saying that's sort of weighing on consumables purchases. But at the same time, you're not getting the switchover to the Nova X, because if you're looking at the order book, you know, the orders have barely grown between Q2 and Q3

[Mike Ryskin, Managing Director of Life Science Tools and Diagnostics Research at Bank of America]

You went from 260 to 310, so orders were up 50 units in the quarter, and you placed 97. So it's not like there's a ton of demand growing for NovaSeq X, and yet the NovaSeq 6000 consumable seems to be really slowing. So I'm just trying to reconcile that. I mean, if people aren't sequencing on the NovaSeq 6000 because they're, you know, gearing up for the NovaSeq X, then you would at least see those orders grow. So how can you confidently state that some of this is that transition between instruments and not just less underlying demand in the market?

[Jacob Thaysen, CEO at Illumina]

Yeah. So let me just start again, address that we do see the demand in the market space. We also mentioned this overall that we see more gigabase growth rates. So we see definitely there's a lot of activities out there. And again, you know, there's no doubt that the long-term perspective in this market is very healthy. I think what you're seeing is that we're running through a very challenging environment that everybody else is seeing. And I think everybody also last year, when they were providing guidance, they were probably optimistic that things would swing back in the second half, and everybody got surprised, or at least that it didn't.

[Jacob Thaysen, CEO at Illumina]

So therefore, we are right now a little more prudent in how we look out in the future. So I think that's one element to it. But if you look into the specifics, I think Joydeep can provide a little more insight.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Yeah, so I, you know, I think, I think the... There's a couple of things when we look at, you know, why is it, you know, further, the slowdown is further impacted by the transition, right? So definitely, Michael, there is an element of the overall macro slowdown. But, two things I, I will tell you about, the transition, right? So we look very carefully at high throughput customers that have purchased the X versus, you know, those that have not purchased an X. And we see definitely that the 6K consumables slowdown is much more pronounced to these customers that have bought the X, right? So that gives us a very good control mechanism of isolating the impact of transition versus the broader macroeconomic trends.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

And again, you know, realize that they're still ramping up with the, with the NovaSeq X and the 25B. Really, for, for many of these customers that are early adopters, they're really the higher, users, the higher, output users for, the NovaSeq X, right? So you will see that transition coming, the ramp up on the, on the NovaSeq X consumables coming, especially after the launch of the 25B, but it will take them a few months to get up to full capacity once they've validated the, their workflows.

[Operator]

...And our next question will come from Tejas Savant with Morgan Stanley.

[Tejas Savant, Executive Director of Life Science Tools and Diagnostics Equity Research at Morgan Stanley]

Hey, guys. Good evening, and, Jacob, welcome to Illumina. I had a couple of questions for you here. Starting on the GRAIL side of things, looks like you're, you know, you're expecting this ECJ decision in mid-2024. So can you just walk us through the implications of that, in terms of what the committee can really do ahead of that timeframe? And then, beyond the ongoing sort of court cases and figuring out, you know, if, then, and how to divest this asset, how are you thinking about monetizing the data value that's embedded within GRAIL? Is that an active discussion that's being had at the board level within this committee as well? And the final part of my question really is a broader one on Core Illumina.

[Tejas Savant, Executive Director of Life Science Tools and Diagnostics Equity Research at Morgan Stanley]

Where are you in terms of, you know, the key leadership roles? Are those... Do you feel like you have a settled team yet, or could we see some sort of significant changes in the months ahead? Thank you.

[Jacob Thaysen, CEO at Illumina]

Yeah. So let me, let me start by addressing the, the GRAIL situation. And I think I've mentioned before, and that's why I put the special committee in place, is that we have the European divestiture order. And obviously, while we still run the appeals, we will do everything within the framework to move as quickly as possible. As I also mentioned in my remarks, is that as soon as we have filed the Form 10, we will go out there and start to talk to potential acquirers and so on. So also looking for the spin and so on. So we are moving as quick as we can within that framework. And we will move. Yeah, again, we will move as much as we can here.

[Jacob Thaysen, CEO at Illumina]

So there's really nothing that holds us back from the appeals really runs in parallel, so there's nothing that prevents us from moving as quick as we can within that. So I think that's, on that, if you look at the monetization of GRAIL, I don't know, Joydeep, do you have any thinking about that?

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

You know, I think mostly it's you're talking about GRAIL data here. So, you know, this is one of the options that obviously the committee will consider, and we will consider as a team, but it also really depends on the divestiture option that's chosen and, you know, what we agree going back and forth with the European Commission here. So, you know, it is one of the things that is absolutely in consideration of the various options that you know, Jacob mentioned, that the committee is going to bring up.

[Jacob Thaysen, CEO at Illumina]

Yeah. Yeah, and then the last question, I think, was on the leadership team, and I will put it more broadly saying that I will be performing a comprehensive business review over the next period of time. As again, I've been here 40 days, and I'm really impressed with the team and the talented people we have in the organization. But I will, of course, keep you updated on what my thinking is while we move forward here in 2024.

[Operator]

We have a question from Dan Leonard with UBS.

[Dan Leonard, Managing Director of Life Science Tools of Services and Diagnostics Equity Research at UBS]

Thank you, and hello, Jacob.

[Jacob Thaysen, CEO at Illumina]

Hello. How are you?

[Dan Leonard, Managing Director of Life Science Tools of Services and Diagnostics Equity Research at UBS]

Now that you're sort of transitioning to maybe a bit more of a, you know, hand-to-mouth demand cycle for the X, given that you don't have much backlog left, I was hoping you could elaborate on what the pipeline looks like, any metrics you could offer, and is it possible you could quantify, you know, how much is the sales cycle lengthening? Is it double what it used to be? Is it some different multiple? Just anything you could help us contextualize that.

[Jacob Thaysen, CEO at Illumina]

I think, Dan, again, I would like to invite, Joydeep in to, to provide a little more insights on, on where we are. But I can say, generally speaking, the sales cycles, is, is extended, quite a lot from what we're used to. Not, not only because it takes time to make the decision, but also, you know, to get it through all the levels, that there's much more scrutiny on, on all levels in, in the decision-making. And, and we've seen that. I mean, we see that in Illumina, but I think that's a general, thing that is happening in the industry right now. But Joydeep, do you wanna go a little closer?

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

I, I just wanna corroborate, Jacob, what you said, right? We see strong interest still in the X, and obviously with the launch of the 25B, that has perked up even more. And the pipeline continues to have hundreds of opportunities there, right? So we're not, we're not suffering a decline in the pipeline. We continue to, to add opportunities to the pipeline. What has been, because of the macroeconomic situation, a little bit more challenging for us, is converting those, that pipeline into orders as quickly as we had imagined, right? So that is the, the lengthening of the sales cycle that, you know, you talked about. And, you know, we expect that that will continue, for us and for others, for, a little bit of time into the future here, right? Till, till macroeconomic conditions return.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

But, you know, there's no doubt that they are not... It's not that the demand is shifting to some other technology or some other instrument. It is still very much centered on the X, and we still continue to have conversations with our customers to get them there. And once they have bought it, to really ramp them up and get them ramped up as quickly as possible so that they can pull through the consumables as quickly as possible.

[Jacob Thaysen, CEO at Illumina]

Yeah, and again, I mean, as Joydeep was saying, we have a healthy pipeline. And just as evidence that this is moving, we just here, over the last few days, received a 10 instrument order on our X from one of our biggest customers. So we're definitely seeing that there is really customers really like the X and can really see that it can be utilized very nicely.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Yeah, Jacob, that's a good point. That's a, that's a fleet expansion order, so, you know, they've had experience with the X, and they, you know, are doubling down, right? So.

[Operator]

... We have a question from Sung Ji Nam with Scotiabank.

[Sung Ji Nam, Managing Director and Senior Equity Research Analyst of Life Science Tools and Diagnostics at Scotiabank]

Hi, thanks for taking the questions, and welcome to Jacob. Just a quick one on GRAIL. Kind of what's the key driver of the, the guidance, updated guidance, being at the, the low end of the prior range? Thanks.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

I can handle this. Yeah. So, again, it's mostly two things. So they did have this particular year some challenges with their PDX revenue. This is the pharma services revenue. And then Galleri sales are, while they're growing nicely, have been lower than their initial expectations, right? So both those have impacted it.

[Jacob Thaysen, CEO at Illumina]

But still a healthy growth.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Still very, very healthy growth. We're seeing that at 100%-ish.

[Operator]

Our next question comes from Kyle Mikson with Canaccord.

[Kyle Mikson, Managing Director of Senior Equity Research Analyst of Life Science Tools and Diagnostics at Canaccord Genuity]

Hey, thanks. Welcome, Jacob. Two-part question. First on GRAIL, second on core. On the GRAIL funding, in conjunction with the divestiture, if it is a capital mortgage transaction, company's gonna need 2.5 years of cash. I think that was touched on earlier. You could provide that via equity raise or debt issuance. Could you just walk through what your exact options are to produce that capital if you don't do an equity or debt offering? And then on the core business, you guys mentioned the initial view on 2024 is that it'll look similar to 2023. Does that mean that revenue is gonna be flat year-over-year for the third year in a row? And then maybe you could just comment on, you know, orders and placements for next year. Like, could placements grow in 2024?

[Kyle Mikson, Managing Director of Senior Equity Research Analyst of Life Science Tools and Diagnostics at Canaccord Genuity]

Thank you.

[Jacob Thaysen, CEO at Illumina]

Yeah. So let me start by the second question here, and again, we will come out with a full guidance in our Q4 2023 call in February. But I'm just sharing you with the initial view we have on 2024 right now, and due to the macroeconomic environment, we want to, and we don't see that change right now. If it changes during 2024, obviously we will see more momentum in the business. But I felt it was important to share with all of you right now as and on how we see the year. There are more details behind it, but we're still working through the rest of this year, and we're still finalizing the 2023 and, of course, 2024 budget also.

[Jacob Thaysen, CEO at Illumina]

So it's too early for me to share details about the deal here. But what I can tell you, as we said before, is that we still have a strong pipeline on X particularly, and we expect, and we just seeing that the sales cycle is taking longer than we expected. But you should actually see that the consumables is starting to pick up in 2024 also.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Yeah. You know, on the GRAIL, I think I've mentioned this earlier. Look, there are several options now on the table that, you know, we could help pay for or, yeah, pay for the 2.5 years of funding requirements, right? So for example, if you went for a spin, there are options around a sponsored spin, where a sponsor could put in a fair chunk of the money, or some or all of the money that is required for that funding. The other one, which is more of a capital markets transaction, which is more of a split kind of option, where you could go and raise money in capital markets for GRAIL and an IPO market for GRAIL.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

So we're looking through and working through those various options. They're of course dependent on specific market conditions and interest in GRAIL from private placement. So we'll keep you posted on that as we go out to the market and consider those options.

[Operator]

We'll take a question from Catherine Schulte with Baird.

[Catherine Schulte, Senior Research Analyst and Director at Baird]

Hey, guys. Thanks for the questions, and welcome, Jacob. I guess just on your comments on 2024, when you say, you know, results might look similar to 2023, you know, in that case, I guess, how do you view Core Illumina op margins? Would those also look similar to 2023? Or given some of the cost reductions that you guys have talked about, do you think there's room for improvement there?

[Jacob Thaysen, CEO at Illumina]

Yeah, thanks for that. So I think right now that Illumina have a wonderful model. Actually, I think we have really strong operating growth margins. So obviously, with growth, we can really fuel that to the bottom also. But in a flat environment, and with, of course, we are seeing that more challenging. So right now we are expecting to be flat both on top line and on the bottom line.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Yeah, and I think, you know, you're right. We do expect to see an improvement in gross margins next year, obviously with, you know, more consumables mixed in there. You know, of the cost reductions that we have made this year, I just want to remind you that some of that, you know, a substantial portion of that has already been recognized this year, so they won't be incremental to next year as we go through. And then offsetting those two positives is, you know, we do expect that the variable compensation, you know, sort of rationalization and year-on-year comp on that will eat away into that goodness that you've had, and coupled with merit increases and inflation, right?

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

So, and again, we did not pay executives the stock-based compensation and you know, variable compensation this year, as our performance has not been up to par. So we do expect that that will come back into next year as we correct some of that.

[Jacob Thaysen, CEO at Illumina]

But I think on that, I think, you know, I'm at everything I see here, as I mentioned, also, the growth margins are strong in the company, but there's a lot we can do to continue to improve that. So I don't see anything that is for me, at least coming in here, see if there's any difference in the thesis about Illumina going back to what has been historically, historical margins. And we will work on that. I think historically, we have been the logic has been this will come through growth, and clearly we need growth to drive some of that, but we will also really focus on operational excellence, see to build that going forward.

[Operator]

Our next question comes from Conor McNamara with RBC Capital Markets.

[Conor McNamara, Equity Research Analyst of Life Science Tools and Diagnostics at RBC Capital Markets]

Hi, guys. Thanks for taking the question, and Jacob, welcome to San Diego. Just if I look at kind of what you've said about 2024, from, you know, from pre-pandemic levels, from 2019 to 2024, that would imply an annual growth rate on the core business of about 5%, which is roughly in line with, you know, the overall life science tools market, despite the fact that you guys have consistently spent about 20% of sales in R&D. So if I'm an investor looking at Illumina, should I think of this as an EBIT margin expansion story from here, where you bring R&D down in line with peers? Or do you think that you guys can drive a return to growth above historic life science tools growth levels?

[Jacob Thaysen, CEO at Illumina]

Yeah, that... I mean, again, I want to be careful on coming with too many comments right now. I'm 40 days into my work here, to my job here. But I think I still believe that Illumina has a better growth opportunity than many of the other life science tools company. And I will come back and give you more insights when I'm ready for it in later in 2024. But I don't think that Illumina is in a place where it's in the level of many of the other companies right now. But it's too early for me to give you a clear guidance. But yeah, so wait and see.

[Operator]

Our next question will come from Rachel Vatnsdal with JPMorgan.

[Rachel Vatnsdal, Senior Equity Research Analyst, Life Science Tools & Diagnostics at JPMorgan]

Great. Thanks for taking the questions, and welcome to Illumina, Jacob. So first up, I just wanted to ask on Core Illumina margins, follow up on some of the earlier questions. Specifically, it looks like that implied 4Q margins stepped down for Core Illumina, but also, given the lower placement number, your mix should be more skewed towards consumables than typical in 4Q. So is there anything else that we should look at from a one-time perspective or anything else on the puts and takes on that margin implied for 4Q?

[Jacob Thaysen, CEO at Illumina]

Joydeep, you want to take that?

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

Yeah. So Rachel, a couple of things, right? So you will see margins and operating margins decline. We are seeing a step down in revenue from Q3 into Q4, so that's one element of that. The second element is gross margins are impacted for several reasons, right? One, that we do see every time you see a reduction in volume, you have less absorption of fixed costs, so you have that flowing into it. The second piece is around, you know, yes, we are seeing some shift from instruments into consumables, but we are seeing a reduction because of the transition effects of NovaSeq 6000 consumables, which are highly profitable, and so you're seeing a little bit of margin, gross margin decline because of that.

[Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer at Illumina]

And then the third is we have some components of strategic deal revenue that we have coming in in Q4 versus Q3, and that is also pulling down our gross margin. So those three components are really what are impacting the gross margin component. And then the operating margin side, I think we obviously are getting some of the benefits of the cost action that we saw, but we did have some movement of R&D-specific timing investments that moved from Q3 into Q4. So that is taking up our Q4 operating expense a little bit compared to what we had in Q3.

[Operator]

Thank you. That does conclude our question and answer session. I will now hand the call back over to Jacob Thaysen for closing remarks.

[Jacob Thaysen, CEO at Illumina]

Thank you, everyone. As we finish the year and move into 2024, I want to reiterate the great foundation that we have here, both in the infrastructure that we have built and in the significant markets that we serve. It is clear to me that there is a tremendous opportunity to create value for our customers and our partners worldwide and, of course, for our shareholders. Thank you again. We're looking forward to see you at upcoming conferences and other events. Thank you.

[Operator]

Thank you. That does conclude today's conference. We do thank you for your participation. Have an excellent day.

Participants

Executives

• Jacob Thaysen, CEO
• Joydeep Goswami, CFO and Chief Strategy and Corporate Development Officer
• Salli Schwartz, VP of Investor Relations

Analysts

• Catherine Schulte, Senior Research Analyst and Director at Baird
• Conor McNamara, Equity Research Analyst of Life Science Tools and Diagnostics at RBC Capital Markets
• Dan Arias, Managing Director of Life Sciences and Diagnostics Research at Stifel
• Dan Brennan, Managing Director in Life Science and Diagnostic Tools Research at TD Cowen
• Dan Leonard, Managing Director of Life Science Tools of Services and Diagnostics Equity Research at UBS
• Kyle Mikson, Managing Director of Senior Equity Research Analyst of Life Science Tools and Diagnostics at Canaccord Genuity
• Mike Ryskin, Managing Director of Life Science Tools and Diagnostics Research at Bank of America
• Puneet Souda, Senior Managing Director of Life Science Tools and Diagnostics at Leerink Partners
• Rachel Vatnsdal, Senior Equity Research Analyst, Life Science Tools & Diagnostics at JPMorgan
• Sung Ji Nam, Managing Director and Senior Equity Research Analyst of Life Science Tools and Diagnostics at Scotiabank
• Tejas Savant, Executive Director of Life Science Tools and Diagnostics Equity Research at Morgan Stanley
• Vijay Kumar, Senior Managing Director in Healthcare Services and Technology Research at Evercore ISI