NASDAQ:ANNX Annexon (ANNX) Stock Price, News & Analysis $2.22 -0.10 (-4.11%) As of 02:28 PM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Annexon Stock (NASDAQ:ANNX) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Annexon alerts:Sign Up Key Stats Today's Range$2.21▼$2.3250-Day Range$2.14▼$2.9652-Week Range$1.28▼$7.85Volume540,643 shsAverage Volume1.55 million shsMarket Capitalization$243.41 millionP/E RatioN/ADividend YieldN/APrice Target$12.50Consensus RatingModerate Buy Company Overview Annexon, Inc., a clinical-stage biopharmaceutical company, discovers and develops medicines for treating inflammatory-related diseases. Its lead candidate is ANX005, an investigational full-length monoclonal antibody, which is in Phase 3 clinical trial for the treatment of patients with guillain-barré syndrome; completed Phase II clinical trial for treating Huntington's disease; and in Phase II clinical trial for the treatment of amyotrophic lateral sclerosis. The company is also developing ANX007, an antigen-binding fragment (Fab) that is in Phase 3 program for the treatment of patients with geographic atrophy; and ANX1502, a novel oral small molecule inhibitor, which is in Phase 1 clinical trials for autoimmune indications. In addition, it develops ANX009, a C1q-blocking Fab that is in Phase I clinical trial for treating patients with lupus nephritis. The company was incorporated in 2011 and is headquartered in Brisbane, California. Read More Annexon Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks59th Percentile Overall ScoreANNX MarketRank™: Annexon scored higher than 59% of companies evaluated by MarketBeat, and ranked 412th out of 932 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.4 / 5Analyst RatingModerate Buy Consensus RatingAnnexon has received a consensus rating of Moderate Buy. The company's average rating score is 2.75, and is based on 3 buy ratings, 1 hold rating, and no sell ratings.Amount of Analyst CoverageAnnexon has only been the subject of 2 research reports in the past 90 days.Read more about Annexon's stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Annexon are expected to decrease in the coming year, from ($0.96) to ($1.06) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Annexon is -1.72, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Annexon is -1.72, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioAnnexon has a P/B Ratio of 0.81. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about Annexon's valuation and earnings. Short Interest3.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted9.94% of the float of Annexon has been sold short.Short Interest Ratio / Days to CoverAnnexon has a short interest ratio ("days to cover") of 6.5.Change versus previous monthShort interest in Annexon has recently decreased by 8.04%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldAnnexon does not currently pay a dividend.Dividend GrowthAnnexon does not have a long track record of dividend growth. Sustainability and ESGN/AEnvironmental ScoreN/A Percentage of Shares Shorted9.94% of the float of Annexon has been sold short.Short Interest Ratio / Days to CoverAnnexon has a short interest ratio ("days to cover") of 6.5.Change versus previous monthShort interest in Annexon has recently decreased by 8.04%, indicating that investor sentiment is improving significantly. News and Social Media2.7 / 5News Sentiment0.90 News SentimentAnnexon has a news sentiment score of 0.90. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.71 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 3 news articles for Annexon this week, compared to 3 articles on an average week.Search InterestOnly 3 people have searched for ANNX on MarketBeat in the last 30 days. This is a decrease of 0% compared to the previous 30 days.MarketBeat Follows3 people have added Annexon to their MarketBeat watchlist in the last 30 days. This is an increase of 200% compared to the previous 30 days. Company Ownership2.5 / 5Insider TradingAcquiring Shares Insider Buying vs. Insider SellingIn the past three months, Annexon insiders have bought 25.96% more of their company's stock than they have sold. Specifically, they have bought $20,122.00 in company stock and sold $15,975.00 in company stock.Percentage Held by Insiders12.67% of the stock of Annexon is held by insiders. A high percentage of insider ownership can be a sign of company health.Read more about Annexon's insider trading history. Receive ANNX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Annexon and its competitors with MarketBeat's FREE daily newsletter. Email Address ANNX Stock News HeadlinesAnnexon Reports Inducement Grant to New Employee Under Nasdaq Listing Rule 5635(c)(4)August 18, 2025 | globenewswire.comJefferies Keeps Their Buy Rating on Annexon Biosciences (ANNX)August 16, 2025 | theglobeandmail.comTake a look at this picture ...A strange investment secret — discovered just a few short weeks before this image was taken — correctly predicted it all. Even crazier, this secret accurately called every major financial event in recent history … Now it's signaling something very scary is about to hit the market again …August 25 at 2:00 AM | Weiss Ratings (Ad)Annexon Biosciences (ANNX) Receives a Buy from Wells FargoAugust 16, 2025 | theglobeandmail.comAnnexon Biosciences Reports Q2 2025 Financial ResultsAugust 15, 2025 | msn.comAnnexon reports Q2 EPS (34c), consensus (36c)August 14, 2025 | msn.comAnnexon Reports Second Quarter 2025 Financial Results, Portfolio Progress and Key Anticipated MilestonesAugust 14, 2025 | globenewswire.comAnnexon Selected by EMA to Participate in Product Development Coordinator Pilot for Vonaprument (ANX007) for Dry Age-Related Macular Degeneration with Geographic AtrophyAugust 7, 2025 | globenewswire.comSee More Headlines ANNX Stock Analysis - Frequently Asked Questions How have ANNX shares performed this year? Annexon's stock was trading at $5.13 on January 1st, 2025. Since then, ANNX shares have decreased by 56.4% and is now trading at $2.2350. How were Annexon's earnings last quarter? Annexon, Inc. (NASDAQ:ANNX) posted its quarterly earnings data on Thursday, August, 14th. The company reported ($0.34) earnings per share for the quarter, beating the consensus estimate of ($0.36) by $0.02. When did Annexon IPO? Annexon (ANNX) raised $150 million in an IPO on Friday, July 24th 2020. The company issued 10,000,000 shares at $14.00-$16.00 per share. J.P. Morgan, BofA Securities and Cowen acted as the underwriters for the IPO. Who are Annexon's major shareholders? Top institutional shareholders of Annexon include Sio Capital Management LLC (3.73%), TFG Asset Management GP Ltd (2.56%), Geode Capital Management LLC (2.08%) and Ameriprise Financial Inc. (1.97%). Insiders that own company stock include Muneer A Satter, Bain Capital Life Sciences Inv, Douglas Love, Michael Overdorf, Jennifer Lew, Ted Yednock, Dean Richard Artis, William H Carson and Jamie Dananberg. View institutional ownership trends. How do I buy shares of Annexon? Shares of ANNX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Annexon own? Based on aggregate information from My MarketBeat watchlists, some other companies that Annexon investors own include NVIDIA (NVDA), MercadoLibre (MELI), Advanced Micro Devices (AMD), Meta Platforms (META), CRISPR Therapeutics (CRSP) and Energy Transfer (ET). Company Calendar Last Earnings8/14/2025Today8/25/2025Next Earnings (Estimated)11/13/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:ANNX CIK1528115 Webwww.annexonbio.com Phone650-822-5500Fax650-636-9773Employees60Year FoundedN/APrice Target and Rating Average Price Target for Annexon$12.50 High Price Target$14.00 Low Price Target$11.00 Potential Upside/Downside+459.3%Consensus RatingModerate Buy Rating Score (0-4)2.75 Research Coverage4 Analysts Profitability EPS (Trailing Twelve Months)($1.29) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$138.20 million Net MarginsN/A Pretax MarginN/A Return on Equity-70.04% Return on Assets-57.67% Debt Debt-to-Equity RatioN/A Current Ratio5.67 Quick Ratio5.67 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book Value$2.75 per share Price / Book0.81Miscellaneous Outstanding Shares109,890,000Free Float95,964,000Market Cap$245.60 million OptionableOptionable Beta1.30 Social Links 7 Stocks That Could Be Bigger Than Tesla, Nvidia, and GoogleLooking for the next FAANG stock before everyone has heard about it? 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