NASDAQ:GUTS Fractyl Health (GUTS) Stock Price, News & Analysis $1.13 -0.02 (-1.74%) Closing price 04:00 PM EasternExtended Trading$1.15 +0.02 (+1.77%) As of 04:31 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsInsider TradesNews and TrendsOwnershipSEC Filings About Fractyl Health Stock (NASDAQ:GUTS) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Fractyl Health alerts:Sign Up Key Stats Today's Range$1.12▼$1.2550-Day Range$1.15▼$9.4152-Week Range$1.11▼$29.34Volume506,813 shsAverage Volume335,511 shsMarket Capitalization$14.98 millionP/E RatioN/ADividend YieldN/APrice Target$50.25Consensus RatingHold Company Overview Fractyl Health, Inc. is a clinical-stage biotechnology company focused on developing therapies for metabolic diseases, including type 2 diabetes and obesity. The company’s approach is based on targeting the biology of the gastrointestinal system and developing treatments intended to address underlying disease mechanisms rather than relying solely on chronic medication. Fractyl Health’s lead product candidate is Revita, an investigational, minimally invasive endoscopic procedure designed to resurface the duodenal lining. The company has studied Revita in patients with type 2 diabetes and is evaluating its potential to improve metabolic control. Fractyl is also developing a gene therapy platform intended to enable durable, potentially long-term production of metabolic hormones such as GLP-1, with the goal of creating a one-time treatment approach for obesity and related metabolic conditions. Founded in 2015 and headquartered in Lexington, Massachusetts, Fractyl Health conducts clinical-stage research and development for its metabolic disease programs. The company was co-founded and is led by Harith Rajagopalan, M.D., Ph.D., who serves as chief executive officer. Fractyl Health became a publicly traded company in 2024 and trades on the Nasdaq under the symbol GUTS.AI Generated. May Contain Errors. Read More Fractyl Health Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks61st Percentile Overall ScoreGUTS MarketRank™: 3.05408271474 of 5 starsFractyl Health scored higher than 61% of companies evaluated by MarketBeat, and ranked 348th out of 903 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.6 / 5Analyst RatingHold Consensus RatingFractyl Health has received a consensus rating of Hold. The company's average rating score is 2.40, and is based on no strong buy ratings, 3 buy ratings, 1 hold rating, and 1 sell rating.Upside PotentialFractyl Health has a consensus price target of $50.25, representing about 4,158.5% upside from its current price of $1.18.Amount of Analyst CoverageFractyl Health has only been the subject of 2 research reports in the past 90 days.Read more about Fractyl Health's stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Fractyl Health are expected to grow in the coming year, from ($5.88) to ($4.85) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Fractyl Health is -0.11, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Fractyl Health is -0.11, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioFractyl Health has a P/B Ratio of 1.42. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.Read more about Fractyl Health's valuation and earnings. Short Interest4.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted17.70% of the float of Fractyl Health has been sold short.Short Interest Ratio / Days to CoverFractyl Health has a short interest ratio ("days to cover") of 1.2, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Fractyl Health has recently decreased by 20.25%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldFractyl Health does not currently pay a dividend.Dividend GrowthFractyl Health does not have a long track record of dividend growth. News and Social Media3.2 / 5News Sentiment0.15 News SentimentFractyl Health has a news sentiment score of 0.15. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.47 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 19 news articles for Fractyl Health this week, compared to 5 articles on an average week.Search Interest20 people have searched for GUTS on MarketBeat in the last 30 days. This is an increase of 150% compared to the previous 30 days.MarketBeat Follows6 people have added Fractyl Health to their MarketBeat watchlist in the last 30 days. Company Ownership0.3 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Fractyl Health insiders have not sold or bought any company stock.Percentage Held by Insiders8.36% of the stock of Fractyl Health is held by insiders.Percentage Held by InstitutionsFractyl Health has minimal institutional ownership at this time.Read more about Fractyl Health's insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. GUTS Stock News HeadlinesFractyl Health, Inc. Announces Executive Changes4 hours ago | marketscreener.comMFractyl Health (GUTS) Stock Sees Fair Value Cut After Mixed Revita Analyst Reactions4 hours ago | finance.yahoo.comYou haven't downloaded this yetBill Poulos's Top 10 Stocks to Buy This Quarter report is still available free, but not for long. Every quarter he swaps in a brand-new list, and once the new edition launches, this one disappears. Investors who want a current snapshot of his picks should grab a copy now and save it before the switch happens.October 22 at 1:00 AM | Profits Run (Ad)Fractyl Health Sharpens Focus on Revita Following Positive Pivotal Results, Advancing Toward Planned FDA De Novo Submission in Post-GLP-1 Weight MaintenanceOctober 22 at 7:00 AM | globenewswire.comMorgan Stanley Has Lowered Expectations for Fractyl Health (NASDAQ:GUTS) Stock PriceOctober 21 at 1:48 AM | americanbankingnews.comPomerantz Law Firm Announces the Filing of a Class Action Against Fractyl Health, Inc. and Certain Officers – GUTSOctober 20 at 3:00 PM | globenewswire.comGUTS CLASS ACTION DEADLINE TONIGHT: Faruqi & Faruqi, LLP Reminds Fractyl (NASDAQ: GUTS) Investors of Securities Class Action Lawsuit Deadline on October 20, 2026October 20 at 9:24 AM | businesswire.comINVESTOR ACTION NOTICE: Moore Law PLLC Encourages Investors in Fractyl Health, Inc. to Contact Law FirmOctober 19 at 7:18 PM | prnewswire.comSee More Headlines GUTS Stock Analysis - Frequently Asked Questions How have GUTS shares performed this year? Fractyl Health's stock was trading at $26.40 at the beginning of the year. Since then, GUTS stock has decreased by 95.5% and is now trading at $1.18. How were Fractyl Health's earnings last quarter? Fractyl Health, Inc. (NASDAQ:GUTS) released its quarterly earnings data on Monday, August, 10th. The company reported ($1.44) earnings per share for the quarter, beating the consensus estimate of ($1.62) by $0.18. Read the conference call transcript. When did Fractyl Health's stock split? Fractyl Health shares reverse split on the morning of Monday, October 5th 2026.A 1-12 reverse split was announced. The number of shares owned by shareholders was adjusted after the closing bell on Sunday, October 4th 2026. An investor that had 100 shares of stock prior to the reverse split would have 8 shares after the split. When did Fractyl Health IPO? Fractyl Health (GUTS) raised $110 million in an initial public offering on Friday, February 2nd 2024. The company issued 7,333,333 shares at a price of $14.00-$16.00 per share. How do I buy shares of Fractyl Health? Shares of GUTS stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Fractyl Health own? Based on aggregate information from My MarketBeat watchlists, some other companies that Fractyl Health investors own include NVIDIA (NVDA), D-Wave Quantum (QBTS), SoFi Technologies (SOFI), Archer Aviation (ACHR), IonQ (IONQ), Tesla (TSLA) and Advanced Micro Devices (AMD). Company Calendar Last Earnings8/10/2026Today10/22/2026Next Earnings (Estimated)11/11/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Red Zone (6d) 1-Year History Oct 25 Jan 26 Apr 26 Jul 26 Oct 26 For the last 6 days, GUTS's financial health has been in the Red zone, according to TradeSmith. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:GUTS Previous SymbolNASDAQ:GUTS CIK1572616 Webfractyl.com Phone781-902-8800FaxN/AEmployees73Year Founded2010Price Target and Rating Average Price Target for Fractyl Health$50.25 High Price Target$96.00 Low Price Target$4.00 Potential Upside/Downside+4,231.9%Consensus RatingHold Rating Score (0-4)2.40 Research Coverage5 Analysts Profitability EPS (Trailing Twelve Months)($10.56) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$140.95 million Net MarginsN/A Pretax MarginN/A Return on Equity-1,362.10% Return on Assets-84.89% Debt Debt-to-Equity Ratio1.41 Current Ratio3.15 Quick Ratio3.15 Sales & Book Value Annual Sales$90 thousand Price / Sales170.91 Cash FlowN/A Price / Cash FlowN/A Book Value$0.83 per share Price / Book1.40Miscellaneous Outstanding Shares13,260,000Free Float12,151,000Market Cap$15.38 million OptionableN/A Beta2.42 Social Links The 7 Hottest IPO Stories of 2026MarketBeat just released its list of the 7 hottest IPOs expected to hit Wall Street in 2026. See which companies are preparing to go public and why investors are watching closely.Get This Free Report This page (NASDAQ:GUTS) was last updated on 10/22/2026 by MarketBeat.com Staff. From Our PartnersYour Social Security check is scheduled for a 22% cutThe U.S. now borrows money just to pay interest on money it already borrowed, a pattern economists call a debt...American Alternative | SponsoredFinancial legend: “This is bad, really bad...”Dr. Martin D. 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