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Fractyl Health (GUTS) Competitors

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$4.16 +0.13 (+3.23%)
As of 02:53 PM Eastern
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GUTS vs. ADCT, EVMN, ALEC, AKBA, and PLX

Should you buy Fractyl Health stock or one of its competitors? Fractyl Health's main competitors and comparable companies include ADC Therapeutics (ADCT), Evommune (EVMN), Alector (ALEC), Akebia Therapeutics (AKBA), and Protalix BioTherapeutics (PLX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Fractyl Health compare to ADC Therapeutics?

Fractyl Health (NASDAQ:GUTS) and ADC Therapeutics (NYSE:ADCT) are both small-cap healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their dividends, valuation, profitability, institutional ownership, risk, analyst recommendations, earnings and media sentiment.

Fractyl Health has a beta of 2.42, suggesting that its stock price is 142% more volatile than the broader market. Comparatively, ADC Therapeutics has a beta of 1.86, suggesting that its stock price is 86% more volatile than the broader market.

Fractyl Health has higher earnings, but lower revenue than ADC Therapeutics. ADC Therapeutics is trading at a lower price-to-earnings ratio than Fractyl Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fractyl HealthN/AN/A-$140.95M-$10.56N/A
ADC Therapeutics$81.36M2.64-$142.62M-$0.66N/A

In the previous week, Fractyl Health had 2 more articles in the media than ADC Therapeutics. MarketBeat recorded 12 mentions for Fractyl Health and 10 mentions for ADC Therapeutics. Fractyl Health's average media sentiment score of 0.14 beat ADC Therapeutics' score of 0.06 indicating that Fractyl Health is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fractyl Health
1 Very Positive mention(s)
0 Positive mention(s)
10 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
ADC Therapeutics
1 Very Positive mention(s)
1 Positive mention(s)
6 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Fractyl Health has a net margin of 0.00% compared to ADC Therapeutics' net margin of -121.77%. ADC Therapeutics' return on equity of 0.00% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Fractyl HealthN/A -1,362.10% -84.89%
ADC Therapeutics -121.77%N/A -32.74%

Fractyl Health presently has a consensus price target of $66.00, suggesting a potential upside of 1,537.72%. ADC Therapeutics has a consensus price target of $5.00, suggesting a potential upside of 196.74%. Given Fractyl Health's stronger consensus rating and higher possible upside, analysts clearly believe Fractyl Health is more favorable than ADC Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
ADC Therapeutics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33

41.1% of ADC Therapeutics shares are held by institutional investors. 8.4% of Fractyl Health shares are held by insiders. Comparatively, 5.1% of ADC Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Summary

Fractyl Health beats ADC Therapeutics on 8 of the 13 factors compared between the two stocks.

How does Fractyl Health compare to Evommune?

Evommune (NYSE:EVMN) and Fractyl Health (NASDAQ:GUTS) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their media sentiment, profitability, analyst recommendations, dividends, earnings, risk, valuation and institutional ownership.

Evommune presently has a consensus target price of $30.80, suggesting a potential upside of 425.15%. Fractyl Health has a consensus target price of $66.00, suggesting a potential upside of 1,537.72%. Given Fractyl Health's higher probable upside, analysts clearly believe Fractyl Health is more favorable than Evommune.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Evommune
1 Sell rating(s)
4 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.69
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

In the previous week, Fractyl Health had 10 more articles in the media than Evommune. MarketBeat recorded 12 mentions for Fractyl Health and 2 mentions for Evommune. Fractyl Health's average media sentiment score of 0.14 beat Evommune's score of 0.00 indicating that Fractyl Health is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Evommune
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Fractyl Health
1 Very Positive mention(s)
0 Positive mention(s)
10 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Evommune's return on equity of -62.63% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
EvommuneN/A -62.63% -40.55%
Fractyl Health N/A -1,362.10%-84.89%

Evommune has higher revenue and earnings than Fractyl Health. Evommune is trading at a lower price-to-earnings ratio than Fractyl Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Evommune$10M21.29-$68.87M-$11.03N/A
Fractyl HealthN/AN/A-$140.95M-$10.56N/A

Summary

Evommune beats Fractyl Health on 7 of the 12 factors compared between the two stocks.

How does Fractyl Health compare to Alector?

Alector (NASDAQ:ALEC) and Fractyl Health (NASDAQ:GUTS) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their dividends, analyst recommendations, profitability, earnings, risk, media sentiment, institutional ownership and valuation.

85.8% of Alector shares are held by institutional investors. 8.3% of Alector shares are held by company insiders. Comparatively, 8.4% of Fractyl Health shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

In the previous week, Fractyl Health had 6 more articles in the media than Alector. MarketBeat recorded 12 mentions for Fractyl Health and 6 mentions for Alector. Alector's average media sentiment score of 0.66 beat Fractyl Health's score of 0.14 indicating that Alector is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Alector
0 Very Positive mention(s)
1 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Fractyl Health
1 Very Positive mention(s)
0 Positive mention(s)
10 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Fractyl Health has a net margin of 0.00% compared to Alector's net margin of -850.13%. Alector's return on equity of -531.03% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Alector-850.13% -531.03% -44.00%
Fractyl Health N/A -1,362.10%-84.89%

Alector currently has a consensus target price of $3.40, indicating a potential upside of 81.82%. Fractyl Health has a consensus target price of $66.00, indicating a potential upside of 1,537.72%. Given Fractyl Health's stronger consensus rating and higher possible upside, analysts plainly believe Fractyl Health is more favorable than Alector.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alector
2 Sell rating(s)
4 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.11
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

Alector has a beta of 0.62, suggesting that its stock price is 38% less volatile than the broader market. Comparatively, Fractyl Health has a beta of 2.42, suggesting that its stock price is 142% more volatile than the broader market.

Fractyl Health has lower revenue, but higher earnings than Alector. Alector is trading at a lower price-to-earnings ratio than Fractyl Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Alector$21.05M9.92-$142.93M-$1.10N/A
Fractyl HealthN/AN/A-$140.95M-$10.56N/A

Summary

Fractyl Health beats Alector on 7 of the 13 factors compared between the two stocks.

How does Fractyl Health compare to Akebia Therapeutics?

Fractyl Health (NASDAQ:GUTS) and Akebia Therapeutics (NASDAQ:AKBA) are both small-cap healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their earnings, analyst recommendations, institutional ownership, profitability, valuation, media sentiment, dividends and risk.

Fractyl Health has a beta of 2.42, meaning that its share price is 142% more volatile than the broader market. Comparatively, Akebia Therapeutics has a beta of 0.18, meaning that its share price is 82% less volatile than the broader market.

Fractyl Health presently has a consensus price target of $66.00, suggesting a potential upside of 1,537.72%. Akebia Therapeutics has a consensus price target of $3.90, suggesting a potential upside of 406.49%. Given Fractyl Health's higher probable upside, equities analysts plainly believe Fractyl Health is more favorable than Akebia Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Akebia Therapeutics
1 Sell rating(s)
2 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.43

33.9% of Akebia Therapeutics shares are owned by institutional investors. 8.4% of Fractyl Health shares are owned by insiders. Comparatively, 4.3% of Akebia Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Akebia Therapeutics has higher revenue and earnings than Fractyl Health. Akebia Therapeutics is trading at a lower price-to-earnings ratio than Fractyl Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fractyl HealthN/AN/A-$140.95M-$10.56N/A
Akebia Therapeutics$236.20M0.90-$5.34M-$0.11N/A

In the previous week, Fractyl Health had 8 more articles in the media than Akebia Therapeutics. MarketBeat recorded 12 mentions for Fractyl Health and 4 mentions for Akebia Therapeutics. Akebia Therapeutics' average media sentiment score of 0.47 beat Fractyl Health's score of 0.14 indicating that Akebia Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fractyl Health
1 Very Positive mention(s)
0 Positive mention(s)
10 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Akebia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Fractyl Health has a net margin of 0.00% compared to Akebia Therapeutics' net margin of -13.54%. Akebia Therapeutics' return on equity of -88.88% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Fractyl HealthN/A -1,362.10% -84.89%
Akebia Therapeutics -13.54%-88.88%-7.74%

Summary

Akebia Therapeutics beats Fractyl Health on 9 of the 14 factors compared between the two stocks.

How does Fractyl Health compare to Protalix BioTherapeutics?

Protalix BioTherapeutics (NYSE:PLX) and Fractyl Health (NASDAQ:GUTS) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two businesses based on the strength of their institutional ownership, valuation, earnings, risk, dividends, analyst recommendations, profitability and media sentiment.

In the previous week, Fractyl Health had 12 more articles in the media than Protalix BioTherapeutics. MarketBeat recorded 12 mentions for Fractyl Health and 0 mentions for Protalix BioTherapeutics. Fractyl Health's average media sentiment score of 0.14 beat Protalix BioTherapeutics' score of 0.00 indicating that Fractyl Health is being referred to more favorably in the news media.

Company Overall Sentiment
Protalix BioTherapeutics Neutral
Fractyl Health Neutral

Protalix BioTherapeutics has a beta of -0.09, suggesting that its share price is 109% less volatile than the broader market. Comparatively, Fractyl Health has a beta of 2.42, suggesting that its share price is 142% more volatile than the broader market.

Fractyl Health has a net margin of 0.00% compared to Protalix BioTherapeutics' net margin of -21.03%. Protalix BioTherapeutics' return on equity of -30.89% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Protalix BioTherapeutics-21.03% -30.89% -11.74%
Fractyl Health N/A -1,362.10%-84.89%

Protalix BioTherapeutics presently has a consensus target price of $12.00, suggesting a potential upside of 336.36%. Fractyl Health has a consensus target price of $66.00, suggesting a potential upside of 1,537.72%. Given Fractyl Health's higher possible upside, analysts plainly believe Fractyl Health is more favorable than Protalix BioTherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protalix BioTherapeutics
0 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
3.00
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

Protalix BioTherapeutics has higher revenue and earnings than Fractyl Health. Fractyl Health is trading at a lower price-to-earnings ratio than Protalix BioTherapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protalix BioTherapeutics$80.62M2.75$8.31M$0.2311.96
Fractyl HealthN/AN/A-$140.95M-$10.56N/A

16.5% of Protalix BioTherapeutics shares are owned by institutional investors. 6.7% of Protalix BioTherapeutics shares are owned by insiders. Comparatively, 8.4% of Fractyl Health shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Summary

Fractyl Health beats Protalix BioTherapeutics on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding GUTS and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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GUTS vs. The Competition

MetricFractyl HealthBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$54.46M$3.91B$7.28B$12.93B
Dividend YieldN/A3.65%2.51%22.89%
P/E Ratio-0.3812.99275.4025.27
Price / SalesN/A1,152.92562.9078.90
Price / CashN/A118.5077.1653.04
Price / Book4.8716.6110.555.93
Net Income-$140.95M-$22.69M$3.50B$380.91M
7 Day Performance-10.62%-6.02%-3.94%-4.21%
1 Month Performance-44.81%-13.82%-8.33%-7.05%
1 Year Performance-75.06%6.88%2.44%-4.87%

Fractyl Health Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
GUTS
Fractyl Health
2.7303 of 5 stars
$4.16
+3.2%
$66.00
+1,486.5%
-74.9%$55.16MN/AN/A73
ADCT
ADC Therapeutics
1.826 of 5 stars
$1.82
+14.2%
$5.00
+175.5%
-63.6%$231.72M$79.58MN/A191
EVMN
Evommune
2.342 of 5 stars
$6.40
-0.2%
$33.33
+420.8%
N/A$230.88M$13MN/A48
ALEC
Alector
2.1781 of 5 stars
$2.08
+2.7%
$3.40
+63.9%
-38.5%$229.46M$13.86MN/A103
AKBA
Akebia Therapeutics
2.3062 of 5 stars
$0.82
+0.5%
$3.90
+376.2%
-72.3%$226.95M$236.20MN/A194

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This page (NASDAQ:GUTS) was last updated on 10/14/2026 by MarketBeat.com Staff.
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