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Fractyl Health (GUTS) Competitors

Fractyl Health logo
$0.69 -0.02 (-2.75%)
As of 09/3/2026 04:00 PM Eastern

GUTS vs. QTTB, PRLD, OCGN, RZLT, and EPRX

Should you buy Fractyl Health stock or one of its competitors? Fractyl Health's main competitors and comparable companies include Q32 Bio (QTTB), Prelude Therapeutics (PRLD), Ocugen (OCGN), Rezolute (RZLT), and Eupraxia Pharmaceuticals (EPRX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Fractyl Health compare to Q32 Bio?

Fractyl Health (NASDAQ:GUTS) and Q32 Bio (NASDAQ:QTTB) are both small-cap healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their analyst recommendations, earnings, dividends, institutional ownership, valuation, risk, media sentiment and profitability.

31.3% of Q32 Bio shares are owned by institutional investors. 8.4% of Fractyl Health shares are owned by company insiders. Comparatively, 34.5% of Q32 Bio shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Q32 Bio's return on equity of 50.17% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Fractyl HealthN/A -1,362.10% -84.89%
Q32 Bio N/A 50.17%29.49%

Fractyl Health has a beta of 2.34, indicating that its share price is 134% more volatile than the broader market. Comparatively, Q32 Bio has a beta of 0.21, indicating that its share price is 79% less volatile than the broader market.

Q32 Bio has higher revenue and earnings than Fractyl Health. Fractyl Health is trading at a lower price-to-earnings ratio than Q32 Bio, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fractyl Health$90K1,215.60-$140.95M-$0.88N/A
Q32 Bio$53.74M7.09$29.82M$3.004.27

In the previous week, Fractyl Health had 20 more articles in the media than Q32 Bio. MarketBeat recorded 23 mentions for Fractyl Health and 3 mentions for Q32 Bio. Q32 Bio's average media sentiment score of 0.43 beat Fractyl Health's score of 0.08 indicating that Q32 Bio is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fractyl Health
2 Very Positive mention(s)
1 Positive mention(s)
18 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Q32 Bio
2 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Fractyl Health presently has a consensus price target of $5.50, suggesting a potential upside of 700.23%. Q32 Bio has a consensus price target of $31.00, suggesting a potential upside of 142.19%. Given Fractyl Health's higher possible upside, equities analysts clearly believe Fractyl Health is more favorable than Q32 Bio.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Q32 Bio
0 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.71

Summary

Q32 Bio beats Fractyl Health on 11 of the 15 factors compared between the two stocks.

How does Fractyl Health compare to Prelude Therapeutics?

Fractyl Health (NASDAQ:GUTS) and Prelude Therapeutics (NASDAQ:PRLD) are both small-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, earnings, institutional ownership, media sentiment, valuation, dividends, risk and profitability.

Prelude Therapeutics' return on equity of -75.35% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Fractyl HealthN/A -1,362.10% -84.89%
Prelude Therapeutics N/A -75.35%-44.39%

Fractyl Health currently has a consensus target price of $5.50, suggesting a potential upside of 700.23%. Prelude Therapeutics has a consensus target price of $7.67, suggesting a potential upside of 46.03%. Given Fractyl Health's higher possible upside, equities research analysts plainly believe Fractyl Health is more favorable than Prelude Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Prelude Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40

Prelude Therapeutics has higher revenue and earnings than Fractyl Health. Prelude Therapeutics is trading at a lower price-to-earnings ratio than Fractyl Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fractyl Health$90K1,215.60-$140.95M-$0.88N/A
Prelude Therapeutics$12.14M34.51-$99.50M-$0.73N/A

In the previous week, Fractyl Health had 21 more articles in the media than Prelude Therapeutics. MarketBeat recorded 23 mentions for Fractyl Health and 2 mentions for Prelude Therapeutics. Fractyl Health's average media sentiment score of 0.08 beat Prelude Therapeutics' score of -0.17 indicating that Fractyl Health is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fractyl Health
2 Very Positive mention(s)
1 Positive mention(s)
18 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Prelude Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Fractyl Health has a beta of 2.34, indicating that its stock price is 134% more volatile than the broader market. Comparatively, Prelude Therapeutics has a beta of 0.97, indicating that its stock price is 3% less volatile than the broader market.

79.7% of Prelude Therapeutics shares are owned by institutional investors. 8.4% of Fractyl Health shares are owned by insiders. Comparatively, 49.2% of Prelude Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

Summary

Prelude Therapeutics beats Fractyl Health on 7 of the 13 factors compared between the two stocks.

How does Fractyl Health compare to Ocugen?

Fractyl Health (NASDAQ:GUTS) and Ocugen (NASDAQ:OCGN) are both small-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their earnings, profitability, institutional ownership, valuation, media sentiment, dividends, analyst recommendations and risk.

In the previous week, Fractyl Health had 16 more articles in the media than Ocugen. MarketBeat recorded 23 mentions for Fractyl Health and 7 mentions for Ocugen. Ocugen's average media sentiment score of 0.66 beat Fractyl Health's score of 0.08 indicating that Ocugen is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fractyl Health
2 Very Positive mention(s)
1 Positive mention(s)
18 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Ocugen
3 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Ocugen has higher revenue and earnings than Fractyl Health. Ocugen is trading at a lower price-to-earnings ratio than Fractyl Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fractyl Health$90K1,215.60-$140.95M-$0.88N/A
Ocugen$4.41M103.81-$67.85M-$0.26N/A

Fractyl Health has a beta of 2.34, meaning that its stock price is 134% more volatile than the broader market. Comparatively, Ocugen has a beta of 2.2, meaning that its stock price is 120% more volatile than the broader market.

10.3% of Ocugen shares are owned by institutional investors. 8.4% of Fractyl Health shares are owned by insiders. Comparatively, 4.0% of Ocugen shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Fractyl Health's return on equity of -1,362.10% beat Ocugen's return on equity.

Company Net Margins Return on Equity Return on Assets
Fractyl HealthN/A -1,362.10% -84.89%
Ocugen N/A -127,987.80%-115.95%

Fractyl Health presently has a consensus price target of $5.50, suggesting a potential upside of 700.23%. Ocugen has a consensus price target of $9.50, suggesting a potential upside of 603.70%. Given Fractyl Health's higher probable upside, equities research analysts plainly believe Fractyl Health is more favorable than Ocugen.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Ocugen
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.60

Summary

Fractyl Health beats Ocugen on 8 of the 15 factors compared between the two stocks.

How does Fractyl Health compare to Rezolute?

Fractyl Health (NASDAQ:GUTS) and Rezolute (NASDAQ:RZLT) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their earnings, media sentiment, dividends, profitability, institutional ownership, analyst recommendations, risk and valuation.

Rezolute has lower revenue, but higher earnings than Fractyl Health. Rezolute is trading at a lower price-to-earnings ratio than Fractyl Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fractyl Health$90K1,215.60-$140.95M-$0.88N/A
RezoluteN/AN/A-$74.41M-$0.82N/A

Fractyl Health has a beta of 2.34, meaning that its stock price is 134% more volatile than the broader market. Comparatively, Rezolute has a beta of 0.6, meaning that its stock price is 40% less volatile than the broader market.

Fractyl Health currently has a consensus target price of $5.50, suggesting a potential upside of 700.23%. Rezolute has a consensus target price of $9.38, suggesting a potential upside of 106.50%. Given Fractyl Health's higher possible upside, research analysts clearly believe Fractyl Health is more favorable than Rezolute.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Rezolute
1 Sell rating(s)
3 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.58

Rezolute's return on equity of -58.82% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Fractyl HealthN/A -1,362.10% -84.89%
Rezolute N/A -58.82%-54.48%

83.0% of Rezolute shares are held by institutional investors. 8.4% of Fractyl Health shares are held by company insiders. Comparatively, 14.8% of Rezolute shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

In the previous week, Fractyl Health had 22 more articles in the media than Rezolute. MarketBeat recorded 23 mentions for Fractyl Health and 1 mentions for Rezolute. Fractyl Health's average media sentiment score of 0.08 beat Rezolute's score of 0.00 indicating that Fractyl Health is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fractyl Health
2 Very Positive mention(s)
1 Positive mention(s)
18 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Rezolute
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Rezolute beats Fractyl Health on 8 of the 14 factors compared between the two stocks.

How does Fractyl Health compare to Eupraxia Pharmaceuticals?

Fractyl Health (NASDAQ:GUTS) and Eupraxia Pharmaceuticals (NASDAQ:EPRX) are both small-cap healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their dividends, media sentiment, risk, institutional ownership, earnings, analyst recommendations, profitability and valuation.

Fractyl Health has a beta of 2.34, indicating that its share price is 134% more volatile than the broader market. Comparatively, Eupraxia Pharmaceuticals has a beta of 1.07, indicating that its share price is 7% more volatile than the broader market.

In the previous week, Fractyl Health had 18 more articles in the media than Eupraxia Pharmaceuticals. MarketBeat recorded 23 mentions for Fractyl Health and 5 mentions for Eupraxia Pharmaceuticals. Eupraxia Pharmaceuticals' average media sentiment score of 1.12 beat Fractyl Health's score of 0.08 indicating that Eupraxia Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Fractyl Health
2 Very Positive mention(s)
1 Positive mention(s)
18 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Eupraxia Pharmaceuticals
3 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Fractyl Health currently has a consensus price target of $5.50, indicating a potential upside of 700.23%. Eupraxia Pharmaceuticals has a consensus price target of $18.00, indicating a potential upside of 140.00%. Given Fractyl Health's higher possible upside, research analysts clearly believe Fractyl Health is more favorable than Eupraxia Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Fractyl Health
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.40
Eupraxia Pharmaceuticals
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
2 Strong Buy rating(s)
2.89

Eupraxia Pharmaceuticals has lower revenue, but higher earnings than Fractyl Health. Eupraxia Pharmaceuticals is trading at a lower price-to-earnings ratio than Fractyl Health, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Fractyl Health$90K1,215.60-$140.95M-$0.88N/A
Eupraxia PharmaceuticalsN/AN/A-$38.58M-$1.02N/A

Eupraxia Pharmaceuticals' return on equity of -63.97% beat Fractyl Health's return on equity.

Company Net Margins Return on Equity Return on Assets
Fractyl HealthN/A -1,362.10% -84.89%
Eupraxia Pharmaceuticals N/A -63.97%-43.32%

Summary

Eupraxia Pharmaceuticals beats Fractyl Health on 7 of the 13 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding GUTS and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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GUTS vs. The Competition

MetricFractyl HealthBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$112.49M$4.03B$7.26B$12.73B
Dividend YieldN/A3.60%2.53%8.86%
P/E Ratio-0.7812.66273.2925.38
Price / Sales1,215.601,309.08613.4592.55
Price / CashN/A106.8777.8252.26
Price / Book-68.7316.2912.896.14
Net Income-$140.95M-$22.72M$3.47B$349.01M
7 Day Performance4.29%0.34%0.60%-0.27%
1 Month Performance0.34%8.52%5.73%0.68%
1 Year Performance-23.62%52.66%25.35%14.84%

Fractyl Health Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
GUTS
Fractyl Health
3.987 of 5 stars
$0.69
-2.7%
$5.50
+700.2%
-26.4%$112.49M$90KN/A102
QTTB
Q32 Bio
3.2291 of 5 stars
$15.49
-4.1%
$31.00
+100.1%
+648.5%$461.14M$53.74M5.1639
PRLD
Prelude Therapeutics
1.7048 of 5 stars
$5.77
-9.0%
$7.67
+32.9%
+330.3%$460.45M$12.14MN/A120
OCGN
Ocugen
1.8794 of 5 stars
$1.34
-2.2%
$9.50
+609.0%
+28.6%$454.37M$4.41MN/A80
RZLT
Rezolute
2.0306 of 5 stars
$4.67
-6.2%
$9.38
+100.7%
-37.3%$449.67MN/AN/A40

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This page (NASDAQ:GUTS) was last updated on 9/4/2026 by MarketBeat.com Staff.
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