AC Immune (ACIU) Competitors $1.73 +0.03 (+1.76%) As of 04/30/2025 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock ACIU vs. TRVI, KROS, VECT, PHAR, VALN, ORGO, CRMD, OPT, UPB, and BCYCShould you be buying AC Immune stock or one of its competitors? The main competitors of AC Immune include Trevi Therapeutics (TRVI), Keros Therapeutics (KROS), VectivBio (VECT), Pharming Group (PHAR), Valneva (VALN), Organogenesis (ORGO), CorMedix (CRMD), Opthea (OPT), Upstream Bio (UPB), and Bicycle Therapeutics (BCYC). These companies are all part of the "pharmaceutical products" industry. AC Immune vs. Trevi Therapeutics Keros Therapeutics VectivBio Pharming Group Valneva Organogenesis CorMedix Opthea Upstream Bio Bicycle Therapeutics AC Immune (NASDAQ:ACIU) and Trevi Therapeutics (NASDAQ:TRVI) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their earnings, community ranking, valuation, media sentiment, analyst recommendations, profitability, dividends, institutional ownership and risk. Does the media favor ACIU or TRVI? In the previous week, Trevi Therapeutics had 1 more articles in the media than AC Immune. MarketBeat recorded 5 mentions for Trevi Therapeutics and 4 mentions for AC Immune. AC Immune's average media sentiment score of 1.54 beat Trevi Therapeutics' score of 1.42 indicating that AC Immune is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment AC Immune 1 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Trevi Therapeutics 4 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Is ACIU or TRVI more profitable? AC Immune's return on equity of -28.26% beat Trevi Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets AC ImmuneN/A -28.26% -18.98% Trevi Therapeutics N/A -63.31%-57.06% Do analysts prefer ACIU or TRVI? AC Immune currently has a consensus target price of $12.00, suggesting a potential upside of 593.64%. Trevi Therapeutics has a consensus target price of $17.56, suggesting a potential upside of 154.16%. Given AC Immune's higher probable upside, equities research analysts clearly believe AC Immune is more favorable than Trevi Therapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score AC Immune 0 Sell rating(s) 0 Hold rating(s) 2 Buy rating(s) 0 Strong Buy rating(s) 3.00Trevi Therapeutics 0 Sell rating(s) 0 Hold rating(s) 7 Buy rating(s) 3 Strong Buy rating(s) 3.30 Does the MarketBeat Community believe in ACIU or TRVI? AC Immune received 154 more outperform votes than Trevi Therapeutics when rated by MarketBeat users. However, 67.95% of users gave Trevi Therapeutics an outperform vote while only 62.65% of users gave AC Immune an outperform vote. CompanyUnderperformOutperformAC ImmuneOutperform Votes26062.65% Underperform Votes15537.35% Trevi TherapeuticsOutperform Votes10667.95% Underperform Votes5032.05% Which has higher valuation and earnings, ACIU or TRVI? Trevi Therapeutics has lower revenue, but higher earnings than AC Immune. Trevi Therapeutics is trading at a lower price-to-earnings ratio than AC Immune, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAC Immune$27.31M6.36-$60.41M-$0.58-2.98Trevi TherapeuticsN/AN/A-$29.07M-$0.47-14.70 Which has more risk & volatility, ACIU or TRVI? AC Immune has a beta of 1.49, suggesting that its stock price is 49% more volatile than the S&P 500. Comparatively, Trevi Therapeutics has a beta of 0.41, suggesting that its stock price is 59% less volatile than the S&P 500. Do institutionals and insiders hold more shares of ACIU or TRVI? 51.4% of AC Immune shares are held by institutional investors. Comparatively, 95.8% of Trevi Therapeutics shares are held by institutional investors. 4.6% of AC Immune shares are held by insiders. Comparatively, 24.4% of Trevi Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth. SummaryTrevi Therapeutics beats AC Immune on 9 of the 17 factors compared between the two stocks. Get AC Immune News Delivered to You Automatically Sign up to receive the latest news and ratings for ACIU and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart ACIU vs. The Competition Export to ExcelMetricAC ImmunePharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$173.71M$6.90B$5.57B$7.82BDividend YieldN/A3.06%5.11%4.22%P/E Ratio-3.767.4522.4218.48Price / Sales6.36242.72394.10103.91Price / CashN/A65.8538.1834.62Price / Book0.826.516.774.25Net Income-$60.41M$143.21M$3.22B$248.23M7 Day Performance9.49%3.97%3.26%3.29%1 Month Performance-12.63%0.37%0.02%2.42%1 Year Performance-30.24%2.60%18.01%5.54% AC Immune Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)ACIUAC Immune2.5403 of 5 stars$1.73+1.8%$12.00+593.6%-30.2%$173.71M$27.31M-3.76140News CoveragePositive NewsTRVITrevi Therapeutics3.6034 of 5 stars$6.02-0.8%$17.56+191.7%+135.8%$582.03MN/A-13.6820Upcoming EarningsNews CoveragePositive NewsKROSKeros Therapeutics3.0986 of 5 stars$14.30+1.6%$40.33+182.1%-74.4%$580.04M$3.55M-2.74100Upcoming EarningsPositive NewsVECTVectivBioN/A$16.85flatN/AN/A$573.24M$27.34M0.0030High Trading VolumePHARPharming Group2.724 of 5 stars$8.15+0.7%$30.00+268.1%-6.6%$554.45M$297.20M-31.35280Upcoming EarningsShort Interest ↓News CoveragePositive NewsGap UpVALNValneva2.5216 of 5 stars$6.63-2.4%$16.00+141.3%-14.9%$538.76M$169.58M-51.00700Upcoming EarningsShort Interest ↓ORGOOrganogenesis3.4345 of 5 stars$4.21-0.2%$5.50+30.6%+108.9%$533.95M$482.04M-70.17950Upcoming EarningsNews CoveragePositive NewsCRMDCorMedix2.4834 of 5 stars$8.14+6.1%$14.50+78.1%+74.9%$530.58M$43.47M-10.0530Upcoming EarningsPositive NewsOPTOpthea0.8095 of 5 stars$3.41+7.2%$1.33-60.9%-0.6%$524.84M$87,666.000.008Gap UpUPBUpstream BioN/A$9.71+10.6%$56.50+481.9%N/A$520.85M$2.37M0.0038News CoveragePositive NewsBCYCBicycle Therapeutics3.0187 of 5 stars$7.51+1.6%$29.14+288.1%-63.5%$519.71M$35.28M-2.28240Short Interest ↓Positive News Related Companies and Tools Related Companies Trevi Therapeutics Competitors Keros Therapeutics Competitors VectivBio Competitors Pharming Group Competitors Valneva Competitors Organogenesis Competitors CorMedix Competitors Opthea Competitors Upstream Bio Competitors Bicycle Therapeutics Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:ACIU) was last updated on 5/1/2025 by MarketBeat.com Staff From Our PartnersHow to invest in Elon Musk’s Optimus before its launchElon Musk is set to completely take over the AI industry with Optimus… A breakthrough AI-powered robot that El...InvestorPlace | SponsoredIs he more powerful than Trump? 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