NASDAQ:BCYC Bicycle Therapeutics (BCYC) Stock Price, News & Analysis $4.53 -0.17 (-3.52%) As of 02:06 PM Eastern This is a fair market value price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Bicycle Therapeutics Stock (NASDAQ:BCYC) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Bicycle Therapeutics alerts:Sign Up Key Stats Today's Range$4.45▼$4.6250-Day Range$4.31▼$5.3352-Week Range$4.24▼$9.36Volume183,138 shsAverage Volume399,043 shsMarket Capitalization$315.89 millionP/E RatioN/ADividend YieldN/APrice Target$14.00Consensus RatingHold Company Overview Bicycle Therapeutics plc is a clinical-stage biotechnology company specializing in the discovery and development of novel peptide therapeutics based on its proprietary bicyclic peptide platform. The company’s core technology leverages constrained peptide structures that combine the binding specificity of biologics with the favorable tissue-penetration properties of small molecules. This approach is designed to generate highly selective drug candidates with potential applications across a range of therapeutic areas, including oncology, neuroscience and immunology. Bicycle Therapeutics maintains a diversified pipeline of internally developed programs as well as collaborations with leading pharmaceutical partners. Its oncology portfolio includes targeted agents aimed at tumor-associated receptors and tumor-penetrating ligands designed to deliver therapeutic payloads. In parallel, the company is advancing candidates in neuroscience and immuno-oncology, seeking to address high-unmet-need conditions. Bicycle’s programs are being evaluated in preclinical and early clinical studies, and the company has established research collaborations with several global biopharmaceutical organizations to accelerate the clinical development of its lead molecules. Headquartered in Cambridge, UK, Bicycle Therapeutics has expanded its presence with operations in the United States to support its growing clinical activities and partnerships. The company is led by an experienced management team with deep expertise in peptide chemistry, translational research and drug development. By integrating its proprietary platform with strategic alliances, Bicycle Therapeutics aims to advance a new class of precision medicines capable of reaching challenging therapeutic targets with improved safety and efficacy profiles.AI Generated. May Contain Errors. Read More Bicycle Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks71st Percentile Overall ScoreBCYC MarketRank™: Bicycle Therapeutics scored higher than 71% of companies evaluated by MarketBeat, and ranked 245th out of 868 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.2 / 5Analyst RatingHold Consensus RatingBicycle Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.44, and is based on no strong buy ratings, 5 buy ratings, 3 hold ratings, and 1 sell rating.Upside PotentialBicycle Therapeutics has a consensus price target of $14.00, representing about 212.9% upside from its current price of $4.47.Amount of Analyst CoverageBicycle Therapeutics has been the subject of 7 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Bicycle Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Bicycle Therapeutics are expected to decrease in the coming year, from ($1.98) to ($2.07) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Bicycle Therapeutics is -1.42, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Bicycle Therapeutics is -1.42, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioBicycle Therapeutics has a P/B Ratio of 0.51. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about Bicycle Therapeutics' valuation and earnings. Short Interest3.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted5.03% of the float of Bicycle Therapeutics has been sold short.Short Interest Ratio / Days to CoverBicycle Therapeutics has a short interest ratio ("days to cover") of 7.57.Change versus previous monthShort interest in Bicycle Therapeutics has recently decreased by 7.68%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldBicycle Therapeutics does not currently pay a dividend.Dividend GrowthBicycle Therapeutics does not have a long track record of dividend growth. News and Social Media2.5 / 5News Sentiment0.93 News SentimentBicycle Therapeutics has a news sentiment score of 0.93. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Medical companies.News Coverage This WeekMarketBeat has tracked 2 news articles for Bicycle Therapeutics this week, compared to 2 articles on an average week.MarketBeat Follows1 people have added Bicycle Therapeutics to their MarketBeat watchlist in the last 30 days. Company Ownership1.7 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Bicycle Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $49,363.00 in company stock.Percentage Held by Insiders8.50% of the stock of Bicycle Therapeutics is held by insiders.Percentage Held by Institutions86.15% of the stock of Bicycle Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Bicycle Therapeutics' insider trading history. 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Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. BCYC Stock News HeadlinesAnalysts Offer Insights on Healthcare Companies: Bicycle Therapeutics (BCYC) and Option Care Health (OPCH)May 31 at 5:52 PM | theglobeandmail.comBicycle Therapeutics PLC Sponsored ADR (NASDAQ:BCYC) Given Consensus Recommendation of "Hold" by BrokeragesMay 25, 2026 | americanbankingnews.comLouis Navellier: My #1 AI stock for 2026 (name & ticker inside)Louis Navellier's Stock Grader system helped him flag Nvidia before its 82,000% run and has identified the top S&P 500 stock for 12 years running—and today, he's giving away his #1 AI stock pick for 2026, free. This company's sales are up 28% year over year, it holds over 30,000 patents in wireless and video technology, and it just earned an A-rating in his proprietary Stock Grader system that has cost him $9 million to build and maintain.June 1 at 1:00 AM | InvestorPlace (Ad)Bicycle Therapeutics Provides Update on Nuzefatide Pevedotin and EphA2 Pipeline at the AACR Annual Meeting 2026April 20, 2026 | businesswire.comRBC Capital lowers its price target on Bicycle Therapeutics plc (BCYC) to $7 from $11April 4, 2026 | msn.comBicycle Therapeutics Plc Sponsored ADRApril 3, 2026 | cnn.comBicycle Therapeutics plc - Depositary Receipt (BCYC) price target decreased by 29.27% to 13.17March 28, 2026 | msn.com12 Best Get Rich Quick Stocks to Buy According to Hedge FundsMarch 14, 2026 | msn.comSee More Headlines BCYC Stock Analysis - Frequently Asked Questions How have BCYC shares performed this year? Bicycle Therapeutics' stock was trading at $7.08 on January 1st, 2026. Since then, BCYC stock has decreased by 36.8% and is now trading at $4.4740. How were Bicycle Therapeutics' earnings last quarter? Bicycle Therapeutics PLC Sponsored ADR (NASDAQ:BCYC) issued its quarterly earnings data on Thursday, April, 30th. The company reported ($0.87) earnings per share (EPS) for the quarter, missing the consensus estimate of ($0.62) by $0.25. The firm had revenue of $0.89 million for the quarter, compared to analyst estimates of $7.50 million. Bicycle Therapeutics had a negative trailing twelve-month return on equity of 35.74% and a negative net margin of 344.95%. When did Bicycle Therapeutics IPO? Bicycle Therapeutics (BCYC) raised $65 million in an IPO on Thursday, May 23rd 2019. The company issued 4,333,333 shares at a price of $14.00-$16.00 per share. Goldman Sachs, Jefferies and Piper Jaffray acted as the underwriters for the IPO and Canaccord Genuity was co-manager. Who are Bicycle Therapeutics' major shareholders? Bicycle Therapeutics' top institutional investors include Siren L.L.C. (2.24%), Principal Financial Group Inc. (1.69%), Renaissance Technologies LLC (1.40%) and Rangeley Capital LLC (0.33%). Insiders that own company stock include Bros Advisors Lp Baker, Kevin Lee, Alistair Milnes, Michael Skynner, Jennifer Scott Perry, Alethia Young, Santiago Arroyo, Travis Alvin Thompson, Nicholas Keen, Michael Charles Ferguso Hannay, Nigel Crockett and Robert Charles Swanton. View institutional ownership trends. How do I buy shares of Bicycle Therapeutics? Shares of BCYC stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Bicycle Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Bicycle Therapeutics investors own include Vale (VALE), uniQure (QURE), Clean Energy Fuels (CLNE), Paycom Software (PAYC), Curaleaf (CURLF) and Company Calendar Last Earnings4/30/2026Today6/01/2026Next Earnings (Estimated)8/14/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Red Zone (50m+) 1-Year History Jun 25 Sep 25 Dec 25 Mar 26 Jun 26 BCYC's financial health is in the Red zone, according to TradeSmith. BCYC has been in this zone for over 50 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry MED - BIOMED/GENE Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:BCYC CIK1761612 Webwww.bicycletherapeutics.com Phone441223261503FaxN/AEmployees240Year Founded2009Price Target and Rating Average Price Target for Bicycle Therapeutics$14.00 High Price Target$36.00 Low Price Target$7.00 Potential Upside/Downside+209.4%Consensus RatingHold Rating Score (0-4)2.44 Research Coverage9 Analysts Profitability EPS (Trailing Twelve Months)($3.15) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$218.96 million Net Margins-344.95% Pretax Margin-342.73% Return on Equity-35.74% Return on Assets-29.54% Debt Debt-to-Equity RatioN/A Current Ratio12.66 Quick Ratio12.66 Sales & Book Value Annual Sales$72.86 million Price / Sales4.34 Cash FlowN/A Price / Cash FlowN/A Book Value$8.79 per share Price / Book0.51Miscellaneous Outstanding Shares69,810,000Free Float63,877,000Market Cap$315.89 million OptionableOptionable Beta1.54 Social Links 7 Stocks That Will Be Magnificent in 2026Discover the next wave of investment opportunities with our report, 7 Stocks That Will Be Magnificent in 2026. Explore companies poised to replicate the growth, innovation, and value creation of the tech giants dominating today's markets.Get This Free Report This page (NASDAQ:BCYC) was last updated on 6/1/2026 by MarketBeat.com Staff. From Our PartnersThe 1934 playbookIn 1934, a legal government maneuver transferred billions in wealth overnight. 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