NASDAQ:BCYC Bicycle Therapeutics (BCYC) Stock Price, News & Analysis $3.68 -0.05 (-1.34%) Closing price 09/25/2026 04:00 PM EasternExtended Trading$3.68 +0.00 (+0.14%) As of 09/25/2026 07:30 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Bicycle Therapeutics Stock (NASDAQ:BCYC) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Bicycle Therapeutics alerts:Sign Up Key Stats Today's Range$3.65▼$3.7350-Day Range$3.60▼$4.3952-Week Range$3.57▼$9.16Volume238,875 shsAverage Volume423,838 shsMarket Capitalization$257.57 millionP/E RatioN/ADividend YieldN/APrice Target$13.86Consensus RatingHold Company Overview Bicycle Therapeutics plc (NASDAQ:BCYC) is a clinical-stage biopharmaceutical company developing medicines based on its proprietary Bicycle technology. The platform uses small, constrained peptides designed to bind selectively to biological targets, with the goal of combining the tissue penetration and manufacturing advantages of small molecules with the target specificity often associated with larger biologic medicines. The company’s research and development activities are focused primarily on oncology. Its pipeline includes Bicycle toxin conjugates, which are designed to deliver cancer-killing payloads to tumor cells, as well as Bicycle molecules intended to modulate immune targets and support other targeted therapeutic approaches. Bicycle Therapeutics has also pursued collaborations and partnered programs to apply its platform across a range of disease areas. Bicycle Therapeutics was founded in 2009 based on research originating at the University of Cambridge and maintains operations in Cambridge, England, and the United States. The company’s programs are developed for potential use in international markets, although most remain in clinical or preclinical development and are subject to regulatory review. Kevin Lee serves as the company’s president and chief executive officer.AI Generated. May Contain Errors. Read More Bicycle Therapeutics Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks56th Percentile Overall ScoreBCYC MarketRank™: Bicycle Therapeutics scored higher than 56% of companies evaluated by MarketBeat, and ranked 436th out of 907 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.6 / 5Analyst RatingHold Consensus RatingBicycle Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.44, and is based on no strong buy ratings, 5 buy ratings, 3 hold ratings, and 1 sell rating.Upside PotentialBicycle Therapeutics has a consensus price target of $13.86, representing about 276.6% upside from its current price of $3.68.Amount of Analyst CoverageBicycle Therapeutics has only been the subject of 2 research reports in the past 90 days.Read more about Bicycle Therapeutics' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthDecreasing Earnings GrowthEarnings for Bicycle Therapeutics are expected to decrease in the coming year, from ($2.26) to ($2.27) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Bicycle Therapeutics is -1.35, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Bicycle Therapeutics is -1.35, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioBicycle Therapeutics has a P/B Ratio of 0.42. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.Read more about Bicycle Therapeutics' valuation and earnings. Short Interest1.0 / 5Short Interest LevelBearish Percentage of Shares Shorted6.10% of the float of Bicycle Therapeutics has been sold short.Short Interest Ratio / Days to CoverBicycle Therapeutics has a short interest ratio ("days to cover") of 6.68.Change versus previous monthShort interest in Bicycle Therapeutics has recently increased by 1.54%, indicating that investor sentiment is decreasing. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldBicycle Therapeutics does not currently pay a dividend.Dividend GrowthBicycle Therapeutics does not have a long track record of dividend growth. News and Social Media3.5 / 5News Sentiment0.61 News SentimentBicycle Therapeutics has a news sentiment score of 0.61. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.73 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 5 news articles for Bicycle Therapeutics this week, compared to 2 articles on an average week.Search Interest1 people have searched for BCYC on MarketBeat in the last 30 days. MarketBeat Follows2 people have added Bicycle Therapeutics to their MarketBeat watchlist in the last 30 days. Company Ownership2.1 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Bicycle Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $42,702.00 in company stock.Percentage Held by Insiders22.00% of the stock of Bicycle Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.Percentage Held by Institutions86.15% of the stock of Bicycle Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Bicycle Therapeutics' insider trading history. Receive BCYC Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Bicycle Therapeutics and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. BCYC Stock News HeadlinesBicycle Therapeutics PLC Sponsored ADR (NASDAQ:BCYC) Receives Average Rating of "Hold" from AnalystsSeptember 27 at 2:28 AM | americanbankingnews.comBicycle Therapeutics Ltd. ADRSeptember 24 at 2:58 PM | barrons.comSmall Colorado Company (Backed by Sam Altman) Could Save U.S. Power GridA small Colorado company has secured rights to technology that could prevent the U.S. public power grid from collapsing — and billionaire Sam Altman is now an investor. This under-the-radar firm is drawing serious attention from those watching the energy infrastructure space closely.September 27 at 1:00 AM | Altimetry (Ad)Critical Contrast: Intellia Therapeutics (NASDAQ:NTLA) & Bicycle Therapeutics (NASDAQ:BCYC)September 21, 2026 | americanbankingnews.comRBC Capital Keeps Their Hold Rating on Bicycle Therapeutics (BCYC)August 5, 2026 | theglobeandmail.comVisa Inks $2.4 Billion Deal to Acquire Fraud Prevention Firm BioCatchAugust 3, 2026 | pymnts.comBicycle Therapeutics Reports Recent Business Progress and Second Quarter 2026 Financial ResultsJuly 30, 2026 | finance.yahoo.comBicycle Therapeutics (NASDAQ:BCYC) Stock, Earnings Estimates, EPS, And RevenueJuly 14, 2026 | benzinga.comSee More Headlines BCYC Stock Analysis - Frequently Asked Questions How have BCYC shares performed this year? Bicycle Therapeutics' stock was trading at $7.08 on January 1st, 2026. Since then, BCYC stock has decreased by 48.0% and is now trading at $3.68. How were Bicycle Therapeutics' earnings last quarter? Bicycle Therapeutics PLC Sponsored ADR (NASDAQ:BCYC) posted its quarterly earnings data on Thursday, July, 30th. The company reported ($0.72) EPS for the quarter, missing analysts' consensus estimates of ($0.58) by $0.14. The company earned $0.63 million during the quarter, compared to the consensus estimate of $4.22 million. Bicycle Therapeutics had a negative trailing twelve-month return on equity of 33.22% and a negative net margin of 311.11%. When did Bicycle Therapeutics IPO? Bicycle Therapeutics (BCYC) raised $65 million in an initial public offering (IPO) on Thursday, May 23rd 2019. The company issued 4,333,333 shares at $14.00-$16.00 per share. Goldman Sachs, Jefferies and Piper Jaffray acted as the underwriters for the IPO and Canaccord Genuity was co-manager. Who are Bicycle Therapeutics' major shareholders? Bicycle Therapeutics' top institutional investors include Marquette Asset Management LLC (0.10%), AXQ Capital LP (0.04%), FNY Investment Advisers LLC (0.04%) and Portland Investment Counsel Inc. (0.02%). Insiders that own company stock include Bros Advisors Lp Baker, Kevin Lee, Alistair Milnes, Michael Skynner, Jennifer Scott Perry, Alethia Young, Santiago Arroyo, Travis Alvin Thompson, Nicholas Keen, Michael Charles Ferguso Hannay, Nigel Crockett and Robert Charles Swanton. View institutional ownership trends. How do I buy shares of Bicycle Therapeutics? Shares of BCYC stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Bicycle Therapeutics own? Based on aggregate information from My MarketBeat watchlists, some other companies that Bicycle Therapeutics investors own include Vale (VALE), uniQure (QURE), Clean Energy Fuels (CLNE), Paycom Software (PAYC), Curaleaf (CURLF) and Company Calendar Last Earnings7/30/2026Today9/27/2026Next Earnings (Estimated)10/29/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Red Zone (54m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 BCYC's financial health is in the Red zone, according to TradeSmith. BCYC has been in this zone for over 54 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:BCYC CIK1761612 Webwww.bicycletherapeutics.com Phone441223261503FaxN/AEmployees288Year Founded2009Price Target and Rating Average Price Target for Bicycle Therapeutics$13.86 High Price Target$36.00 Low Price Target$7.00 Potential Upside/Downside+276.6%Consensus RatingHold Rating Score (0-4)2.44 Research Coverage9 Analysts Profitability EPS (Trailing Twelve Months)($2.73) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$218.96 million Net Margins-311.11% Pretax Margin-308.27% Return on Equity-33.22% Return on Assets-27.79% Debt Debt-to-Equity RatioN/A Current Ratio12.08 Quick Ratio12.08 Sales & Book Value Annual Sales$61.21 million Price / Sales4.21 Cash FlowN/A Price / Cash FlowN/A Book Value$8.79 per share Price / Book0.42Miscellaneous Outstanding Shares69,993,000Free Float54,595,000Market Cap$257.57 million OptionableOptionable Beta1.54 Social Links 7 Stocks That Could Lead the Next Market BoomTesla, Nvidia, and Google helped shape the last era of market growth, but the next wave could come from a new group of companies. 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