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NASDAQ:BCYC

Bicycle Therapeutics (BCYC) Stock Price, News & Analysis

Bicycle Therapeutics logo
$4.06 -0.06 (-1.46%)
As of 08/12/2026 04:00 PM Eastern

About Bicycle Therapeutics Stock (NASDAQ:BCYC)

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Key Stats

Today's Range
$4.04
$4.15
50-Day Range
$3.86
$4.41
52-Week Range
$3.74
$9.16
Volume
639,900 shs
Average Volume
276,025 shs
Market Capitalization
$283.43 million
P/E Ratio
N/A
Dividend Yield
N/A
Price Target
$13.86
Consensus Rating
Hold

Company Overview

Bicycle Therapeutics plc is a clinical-stage biotechnology company specializing in the discovery and development of novel peptide therapeutics based on its proprietary bicyclic peptide platform. The company’s core technology leverages constrained peptide structures that combine the binding specificity of biologics with the favorable tissue-penetration properties of small molecules. This approach is designed to generate highly selective drug candidates with potential applications across a range of therapeutic areas, including oncology, neuroscience and immunology.

Bicycle Therapeutics maintains a diversified pipeline of internally developed programs as well as collaborations with leading pharmaceutical partners. Its oncology portfolio includes targeted agents aimed at tumor-associated receptors and tumor-penetrating ligands designed to deliver therapeutic payloads. In parallel, the company is advancing candidates in neuroscience and immuno-oncology, seeking to address high-unmet-need conditions. Bicycle’s programs are being evaluated in preclinical and early clinical studies, and the company has established research collaborations with several global biopharmaceutical organizations to accelerate the clinical development of its lead molecules.

Headquartered in Cambridge, UK, Bicycle Therapeutics has expanded its presence with operations in the United States to support its growing clinical activities and partnerships. The company is led by an experienced management team with deep expertise in peptide chemistry, translational research and drug development. By integrating its proprietary platform with strategic alliances, Bicycle Therapeutics aims to advance a new class of precision medicines capable of reaching challenging therapeutic targets with improved safety and efficacy profiles.

AI Generated. May Contain Errors.

Bicycle Therapeutics Stock Analysis - MarketRank™

See Top-Rated MarketRank™ Stocks
69th Percentile Overall Score

BCYC MarketRank™: 

Bicycle Therapeutics scored higher than 69% of companies evaluated by MarketBeat, and ranked 306th out of 911 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

  • Consensus Rating

    Bicycle Therapeutics has received a consensus rating of Hold. The company's average rating score is 2.44, and is based on no strong buy ratings, 5 buy ratings, 3 hold ratings, and 1 sell rating.

  • Upside Potential

    Bicycle Therapeutics has a consensus price target of $13.86, representing about 241.3% upside from its current price of $4.06.

  • Amount of Analyst Coverage

    Bicycle Therapeutics has only been the subject of 3 research reports in the past 90 days.

  • Read more about Bicycle Therapeutics' stock forecast and price target.
  • Earnings Growth

    Earnings for Bicycle Therapeutics are expected to grow in the coming year, from ($2.23) to ($2.20) per share.

  • Price to Earnings Ratio vs. the Market

    The P/E ratio of Bicycle Therapeutics is -1.49, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Earnings Ratio vs. Sector

    The P/E ratio of Bicycle Therapeutics is -1.49, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Book Value per Share Ratio

    Bicycle Therapeutics has a P/B Ratio of 0.56. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.

  • Read more about Bicycle Therapeutics' valuation and earnings.
  • Percentage of Shares Shorted

    5.48% of the float of Bicycle Therapeutics has been sold short.
  • Short Interest Ratio / Days to Cover

    Bicycle Therapeutics has a short interest ratio ("days to cover") of 9.89.
  • Change versus previous month

    Short interest in Bicycle Therapeutics has recently increased by 0.03%, indicating that investor sentiment is decreasing.
  • Dividend Yield

    Bicycle Therapeutics does not currently pay a dividend.

  • Dividend Growth

    Bicycle Therapeutics does not have a long track record of dividend growth.

  • News Sentiment

    Bicycle Therapeutics has a news sentiment score of 0.86. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.66 average news sentiment score of Healthcare companies.
  • News Coverage This Week

    MarketBeat has tracked 4 news articles for Bicycle Therapeutics this week, compared to 3 articles on an average week.
  • MarketBeat Follows

    1 people have added Bicycle Therapeutics to their MarketBeat watchlist in the last 30 days.
  • Insider Buying vs. Insider Selling

    In the past three months, Bicycle Therapeutics insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $42,702.00 in company stock.

  • Percentage Held by Insiders

    22.00% of the stock of Bicycle Therapeutics is held by insiders. A high percentage of insider ownership can be a sign of company health.

  • Percentage Held by Institutions

    86.15% of the stock of Bicycle Therapeutics is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

  • Read more about Bicycle Therapeutics' insider trading history.
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BCYC Stock News Headlines

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BCYC Stock Analysis - Frequently Asked Questions

Bicycle Therapeutics' stock was trading at $7.08 at the beginning of 2026. Since then, BCYC shares have decreased by 42.7% and is now trading at $4.06.

Bicycle Therapeutics PLC Sponsored ADR (NASDAQ:BCYC) announced its quarterly earnings data on Thursday, July, 30th. The company reported ($0.72) EPS for the quarter, missing the consensus estimate of ($0.58) by $0.14. The company earned $0.63 million during the quarter, compared to analyst estimates of $4.22 million. Bicycle Therapeutics had a negative net margin of 311.11% and a negative trailing twelve-month return on equity of 33.22%.

Bicycle Therapeutics (BCYC) raised $65 million in an IPO on Thursday, May 23rd 2019. The company issued 4,333,333 shares at $14.00-$16.00 per share. Goldman Sachs, Jefferies and Piper Jaffray acted as the underwriters for the IPO and Canaccord Genuity was co-manager.

Top institutional shareholders of Bicycle Therapeutics include Marquette Asset Management LLC (0.10%), FNY Investment Advisers LLC (0.04%) and GAMMA Investing LLC (0.01%). Insiders that own company stock include Bros Advisors Lp Baker, Kevin Lee, Alistair Milnes, Michael Skynner, Jennifer Scott Perry, Alethia Young, Santiago Arroyo, Travis Alvin Thompson, Nicholas Keen, Michael Charles Ferguso Hannay, Nigel Crockett and Robert Charles Swanton.
View institutional ownership trends
.

Shares of BCYC stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

Based on aggregate information from My MarketBeat watchlists, some other companies that Bicycle Therapeutics investors own include Vale (VALE), uniQure (QURE), Clean Energy Fuels (CLNE), Paycom Software (PAYC), Curaleaf (CURLF) and

Company Calendar

Last Earnings
7/30/2026
Today
8/13/2026
Next Earnings (Estimated)
10/29/2026
Fiscal Year End
12/31/2026

Industry, Sector and Symbol

Stock Exchange
NASDAQ
Industry
Biotechnology
Sub-Industry
Biotechnology
Current Symbol
NASDAQ:BCYC
CIK
1761612
Fax
N/A
Employees
240
Year Founded
2009

Price Target and Rating

High Price Target
$36.00
Low Price Target
$7.00
Potential Upside/Downside
+241.3%
Consensus Rating
Hold
Rating Score (0-4)
2.44
Research Coverage
9 Analysts

Profitability

EPS (Trailing Twelve Months)
($2.73)
Trailing P/E Ratio
N/A
Forward P/E Ratio
N/A
P/E Growth
N/A
Net Income
-$218.96 million
Net Margins
-311.11%
Pretax Margin
-308.27%
Return on Equity
-33.22%
Return on Assets
-27.79%

Debt

Debt-to-Equity Ratio
N/A
Current Ratio
12.08
Quick Ratio
12.08

Sales & Book Value

Annual Sales
$72.86 million
Price / Sales
3.89
Cash Flow
N/A
Price / Cash Flow
N/A
Book Value
$7.31 per share
Price / Book
0.56

Miscellaneous

Outstanding Shares
69,810,000
Free Float
54,453,000
Market Cap
$283.43 million
Optionable
Optionable
Beta
1.55

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This page (NASDAQ:BCYC) was last updated on 8/13/2026 by MarketBeat.com Staff.
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